AR029211A1 - Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprenden - Google Patents
Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprendenInfo
- Publication number
- AR029211A1 AR029211A1 ARP000106795A ARP000106795A AR029211A1 AR 029211 A1 AR029211 A1 AR 029211A1 AR P000106795 A ARP000106795 A AR P000106795A AR P000106795 A ARP000106795 A AR P000106795A AR 029211 A1 AR029211 A1 AR 029211A1
- Authority
- AR
- Argentina
- Prior art keywords
- manufacture
- pharmaceutical compositions
- derivatives
- oxazoles
- understand
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000002916 oxazoles Chemical class 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 150000007978 oxazole derivatives Chemical class 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Derivados de oxazoles que comprenden compuestos de la formula 1 o una de sus sales farmacéuticamente aceptables y que tienen potente actividad contra las bacterias grampositivas y gramnegativas, en donde: A es una estructura 2, 3, 4 o 5; B es (a) 6; (b) es 7 o (c) es 8; W es NHC(=X) R1 o Y -het, con la condicion de que cuando A es una estructura 5, W no es -Y-het; X es O o S con la condicion de que cuando X es o, B no es la subseccion (b). Y es NH, O o S; Z es S (=O) (=N-R5);Además se describe el uso de las mismas para la manufactura de un medicamento para el tratamiento médico de infecciones microbianas en un mamífero y composiciones farmacéuticas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17191699P | 1999-12-21 | 1999-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR029211A1 true AR029211A1 (es) | 2003-06-18 |
Family
ID=22625632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000106795A AR029211A1 (es) | 1999-12-21 | 2000-12-20 | Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprenden |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20010046987A1 (es) |
| EP (1) | EP1242417A1 (es) |
| JP (1) | JP2003518117A (es) |
| KR (1) | KR20020067557A (es) |
| CN (1) | CN1221548C (es) |
| AR (1) | AR029211A1 (es) |
| AU (1) | AU782078B2 (es) |
| BR (1) | BR0016605A (es) |
| CA (1) | CA2389482A1 (es) |
| CO (1) | CO5251427A1 (es) |
| CZ (1) | CZ20022142A3 (es) |
| EA (1) | EA005567B1 (es) |
| HU (1) | HUP0203869A2 (es) |
| IL (1) | IL150348A0 (es) |
| MX (1) | MXPA02006233A (es) |
| NO (1) | NO20022973L (es) |
| NZ (1) | NZ519725A (es) |
| PE (1) | PE20010931A1 (es) |
| PL (1) | PL356478A1 (es) |
| SK (1) | SK7572002A3 (es) |
| WO (1) | WO2001046185A1 (es) |
| ZA (1) | ZA200204166B (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| GB0108764D0 (en) * | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
| GB0108793D0 (en) * | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
| JP2004531518A (ja) * | 2001-04-07 | 2004-10-14 | アストラゼネカ アクチボラグ | スルホンイミド基を含有する、抗生物質としてのオキサゾリジノン |
| GB0108794D0 (en) * | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compound |
| DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| US7141588B2 (en) | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| AR038536A1 (es) | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| TW200403240A (en) | 2002-06-28 | 2004-03-01 | Upjohn Co | Difluorothioacetamides of oxazolidinones as antibacterial agents |
| US6875784B2 (en) | 2002-10-09 | 2005-04-05 | Pharmacia & Upjohn Company | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives |
| DE10300111A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| CA2521685A1 (en) * | 2003-04-09 | 2004-10-21 | Pharmacia & Upjohn Company Llc | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues |
| US7304050B2 (en) | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| US7265140B2 (en) * | 2003-09-23 | 2007-09-04 | Pfizer Inc | Acyloxymethylcarbamate prodrugs of oxazolidinones |
| DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| WO2006056877A2 (en) * | 2004-11-29 | 2006-06-01 | Pharmacia & Upjohn Company Llc | Diazepine oxazolidinones as antibacterial agents |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| EP1685841A1 (en) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
| DK1899331T3 (da) | 2005-06-29 | 2010-03-08 | Pharmacia & Upjohn Co Llc | Homomorpholinoxazolidnoner som antibakterielle midler |
| DE102005045518A1 (de) * | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| DE102005047558A1 (de) * | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| PT1934208E (pt) | 2005-10-04 | 2011-06-01 | Bayer Schering Pharma Ag | Nova forma polimorfa de 5-cloro-n-({(5s)-2-oxo-3-[4-(3- oxo-4-morfolinil)-fenil]-1,3-oxazolidin-5-il}-metil)-2- tiofenocarboxamida |
| DE102007028319A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| WO2021184339A1 (en) | 2020-03-20 | 2021-09-23 | Merck Sharp & Dohme Corp. | Oxazolidinone compound and methods of use thereof as an antibacterial agent |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| MY115155A (en) * | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| CN1046520C (zh) * | 1994-11-15 | 1999-11-17 | 法玛西雅厄普约翰美国公司 | 二环噁嗪及噻嗪噁唑烷酮抗菌剂 |
| AU716493B2 (en) * | 1995-09-01 | 2000-02-24 | Pharmacia & Upjohn Company | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings |
| ES2242280T3 (es) * | 1997-05-30 | 2005-11-01 | PHARMACIA & UPJOHN COMPANY LLC | Agentes antibacterianos de oxazolidinona que contienen funcionalidad tiocarbonilo. |
-
2000
- 2000-12-12 BR BR0016605-7A patent/BR0016605A/pt not_active IP Right Cessation
- 2000-12-12 EP EP00983792A patent/EP1242417A1/en not_active Withdrawn
- 2000-12-12 EA EA200200699A patent/EA005567B1/ru not_active IP Right Cessation
- 2000-12-12 CN CNB008160449A patent/CN1221548C/zh not_active Expired - Fee Related
- 2000-12-12 CZ CZ20022142A patent/CZ20022142A3/cs unknown
- 2000-12-12 KR KR1020027007958A patent/KR20020067557A/ko not_active Withdrawn
- 2000-12-12 AU AU20502/01A patent/AU782078B2/en not_active Ceased
- 2000-12-12 HU HU0203869A patent/HUP0203869A2/hu unknown
- 2000-12-12 PL PL00356478A patent/PL356478A1/xx not_active Application Discontinuation
- 2000-12-12 JP JP2001547095A patent/JP2003518117A/ja active Pending
- 2000-12-12 IL IL15034800A patent/IL150348A0/xx unknown
- 2000-12-12 CA CA002389482A patent/CA2389482A1/en not_active Abandoned
- 2000-12-12 MX MXPA02006233A patent/MXPA02006233A/es unknown
- 2000-12-12 SK SK757-2002A patent/SK7572002A3/sk unknown
- 2000-12-12 WO PCT/US2000/032451 patent/WO2001046185A1/en not_active Ceased
- 2000-12-12 NZ NZ519725A patent/NZ519725A/en unknown
- 2000-12-14 US US09/736,858 patent/US20010046987A1/en not_active Abandoned
- 2000-12-19 PE PE2000001363A patent/PE20010931A1/es not_active Application Discontinuation
- 2000-12-20 CO CO00096639A patent/CO5251427A1/es not_active Application Discontinuation
- 2000-12-20 AR ARP000106795A patent/AR029211A1/es unknown
-
2002
- 2002-05-24 ZA ZA200204166A patent/ZA200204166B/xx unknown
- 2002-06-20 NO NO20022973A patent/NO20022973L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20022973L (no) | 2002-08-20 |
| CN1391572A (zh) | 2003-01-15 |
| WO2001046185A1 (en) | 2001-06-28 |
| CA2389482A1 (en) | 2001-06-28 |
| SK7572002A3 (en) | 2002-12-03 |
| EA200200699A1 (ru) | 2003-02-27 |
| CZ20022142A3 (cs) | 2002-11-13 |
| IL150348A0 (en) | 2002-12-01 |
| JP2003518117A (ja) | 2003-06-03 |
| NZ519725A (en) | 2004-05-28 |
| EA005567B1 (ru) | 2005-04-28 |
| US20010046987A1 (en) | 2001-11-29 |
| CO5251427A1 (es) | 2003-02-28 |
| KR20020067557A (ko) | 2002-08-22 |
| CN1221548C (zh) | 2005-10-05 |
| PL356478A1 (en) | 2004-06-28 |
| PE20010931A1 (es) | 2001-08-29 |
| NO20022973D0 (no) | 2002-06-20 |
| AU2050201A (en) | 2001-07-03 |
| MXPA02006233A (es) | 2002-12-05 |
| ZA200204166B (en) | 2003-10-29 |
| AU782078B2 (en) | 2005-06-30 |
| EP1242417A1 (en) | 2002-09-25 |
| HUP0203869A2 (hu) | 2003-07-28 |
| BR0016605A (pt) | 2003-02-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR029211A1 (es) | Derivados de oxazoles, el uso de los mismos para la manufactura de un medicamento y composiciones farmaceuticas que los comprenden | |
| CU23423B7 (es) | Oxazolidinonas sustituidas y su uso en el campo de la coagulación sanguínea | |
| GEP20063799B (en) | Tropane derivatives useful in therapy | |
| AR029226A1 (es) | Tioamidas, composiciones farmaceuticas y el uso de la misma para la fabricacion de compuestos medicinales | |
| AR020001A1 (es) | COMPUESTOS ACTIVADORES DE hPPARGAMMA Y hPPARALFA, COMPOSICIONES FARMACEUTICAS QUE LOS COMPRENDEN, METODO PARA EL TRATAMIENTO Y/O PREVENCION DE UNAENFERMEDAD MEDIADA POR LOS MISMOS, Y SU USO PARA LA ELABORACION DE UN MEDICAMENTO | |
| NO20085078L (no) | Nye forbindelser | |
| MY127126A (en) | Imidazolo-5-yl-2-anilino-pyrimidines as agents for the inhibition of the cell proliferation | |
| CO5170471A1 (es) | Tabletas de liberacion modificada que incluyen amoxilina y clavulanato de potasio | |
| AR050838A1 (es) | Formulacion farmaceutica. para el tratamiento de una infeccion optica | |
| AR004510A1 (es) | Composiciones que comprenden amoxicilina y clavulanato, procedimientos para su preparacion y el uso de las composiciones para la fabricacion de unmedicamento | |
| ES2092890T3 (es) | Aplicacion del riluzol en el tratamiento de la enfermedad de parkinson y de los sindromes de parkinson. | |
| NO20065904L (no) | Terapeutiske forbindelser | |
| AR019853A1 (es) | Derivado del acido 3-aril-2-hidroxipropionico, proceso e intermediario para su preparacion, formulaciones farmaceuticas, uso de dicho compuesto en laelaboracion de un medicamento, metodo para la profilaxis y/o tratamiento de trastornos clinicos asociados con la resistencia a la insulina, y formulaci | |
| PA8485601A1 (es) | Azalidas de 13 miembros y su uso como agentes antibioticos. | |
| RU2002100058A (ru) | Кристаллические производные 1-метилкарбапенема | |
| ES2098947T3 (es) | Derivados de beta,beta-dimetil-4-piperidinoetanamina como inhibidores de la biosintesis del colesterol. | |
| SE0300908D0 (sv) | Azaindole derivatives, preparations thereof, uses thereof and compositions containing them | |
| AR032138A1 (es) | Derivados de 6-hidroxi-indazol, una composicion oftalmica, y el uso de dichos derivados para la manufactura de un medicamento para el tratamiento de glaucoma | |
| NO304113B1 (no) | Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament | |
| GEP20084437B (en) | Novel lincomycin derivatives possessing antimicrobial activity | |
| AR029412A1 (es) | Forma cristalina | |
| SE0301701D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| UY29085A1 (es) | Derivados de pirimidina 4-sulfonamido sustituidos, compuestos intermedios para su preparación, procedimientos de preparación, composiciones medicinales conteniéndolos y aplicaci0nes | |
| NO20060146L (no) | Benzimidazolderivater, sammensetninger som inneholder slike, fremstilling derav og anvendelse derav | |
| EA202092579A1 (ru) | Оксозамещенное соединение |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |