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AR011709A1 - Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal - Google Patents

Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal

Info

Publication number
AR011709A1
AR011709A1 ARP980101575A ARP980101575A AR011709A1 AR 011709 A1 AR011709 A1 AR 011709A1 AR P980101575 A ARP980101575 A AR P980101575A AR P980101575 A ARP980101575 A AR P980101575A AR 011709 A1 AR011709 A1 AR 011709A1
Authority
AR
Argentina
Prior art keywords
vaginal administration
ring
preference
application system
drug application
Prior art date
Application number
ARP980101575A
Other languages
English (en)
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8228203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR011709(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organon Nv filed Critical Organon Nv
Publication of AR011709A1 publication Critical patent/AR011709A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion se relaciona con un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracionvaginal, para la liberacion simultánea de un compuesto esteroide progestogénico en una relacionfis iologica fija en un lapso prolongado. El sistema deaplicacion de drogas comprende al menos un comportamiento de comprende un nucleo polimérico termoplástico que contiene la mezcla de los compuestosprogestogénico y estrogénico y una pielpolméri ca termoplástica, estando el compuesto porgestogénico disuelto inicialmente en el material poliméricocentral en un grado relativamente bajo de supersaturacion.
ARP980101575A 1997-04-11 1998-04-07 Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal AR011709A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201098 1997-04-11

Publications (1)

Publication Number Publication Date
AR011709A1 true AR011709A1 (es) 2000-08-30

Family

ID=8228203

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980101575A AR011709A1 (es) 1997-04-11 1998-04-07 Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal

Country Status (26)

Country Link
US (1) US5989581A (es)
EP (1) EP0876815B1 (es)
JP (2) JP4982670B2 (es)
KR (1) KR100492676B1 (es)
CN (1) CN1163222C (es)
AR (1) AR011709A1 (es)
AT (1) ATE211646T1 (es)
AU (1) AU726934B2 (es)
BR (1) BR9801027B1 (es)
CA (1) CA2233753C (es)
CZ (1) CZ294099B6 (es)
DE (1) DE69803112T2 (es)
DK (1) DK0876815T3 (es)
ES (1) ES2171283T3 (es)
HU (1) HU222343B1 (es)
ID (1) ID21259A (es)
IL (2) IL123813A0 (es)
NO (1) NO320394B1 (es)
NZ (1) NZ330145A (es)
PL (1) PL192449B1 (es)
PT (1) PT876815E (es)
RU (1) RU2206325C2 (es)
SG (1) SG65061A1 (es)
TR (1) TR199800648A1 (es)
TW (1) TW358031B (es)
ZA (1) ZA982911B (es)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW358031B (en) * 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances
US6039968A (en) 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6361780B1 (en) * 1998-11-12 2002-03-26 Cardiac Pacemakers, Inc. Microporous drug delivery system
US6217895B1 (en) 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6371970B1 (en) 1999-07-30 2002-04-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US7369463B1 (en) 2000-02-21 2008-05-06 N.V. Organon Electronic alarm timer for use with a medical regimen
US6375972B1 (en) * 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US20040115268A1 (en) * 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
US7187980B2 (en) * 2001-11-09 2007-03-06 Oscor Inc. Cardiac lead with steroid eluting ring
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
KR20100120243A (ko) * 2002-05-07 2010-11-12 피시비다 유에스 인코포레이티드 약물 전달 장치를 형성하는 공정
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
HRP20050396A2 (en) 2002-11-07 2005-06-30 Akzo Nobel N.V. Indoles useful in the treatment of androgen-receptor related diseases
US7357046B2 (en) * 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
ATE373108T1 (de) * 2002-12-16 2007-09-15 Organon Nv Behälter ,vorrichtung und verfahren zur prüfung des auflösens von pharmazeutischen zusammensetzungen
JP4898431B2 (ja) * 2003-04-29 2012-03-14 ザ ジェネラル ホスピタル コーポレイション 複数薬物の持続放出のための方法およびデバイス
TWI336627B (en) * 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
EP1709060A1 (en) * 2004-01-15 2006-10-11 Warner Chilcott Company Inc. Di-steroidal prodrugs of estradiol
US7067504B2 (en) * 2004-01-15 2006-06-27 Warner Chilcott Company, Inc. Di-steroidal prodrugs of ethinyl estradiol
JP2007530500A (ja) * 2004-03-24 2007-11-01 ナームローゼ・フエンノートチヤツプ・オルガノン ポリエチレン酢酸ビニル共重合体に基づく薬物送達システム
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators
TW200602317A (en) 2004-04-23 2006-01-16 Akzo Nobel Nv Novel androgens
CN101137347A (zh) * 2004-11-16 2008-03-05 列日大学 包含水凝胶基质和微载体的活性物质递送系统
CN100366242C (zh) * 2005-01-13 2008-02-06 杭州容立医药科技有限公司 防滑脱阴道药物释放体系及其制造工艺和在制药中的应用
JP2008543499A (ja) * 2005-06-20 2008-12-04 アビームーア メディカル インコーポレイテッド 自動調整尿道内装置およびその使用法
TW200744610A (en) * 2005-06-21 2007-12-16 Organon Nv New regimens for controlled drug delivery devices for contraception
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
EP2390260B1 (en) 2005-07-12 2014-09-17 Warner Chilcott Company, LLC Ester derivative of ethinyl estradiol
CN101228177A (zh) * 2005-07-12 2008-07-23 沃纳奇尔科特公司 雌二醇的3-酯前药
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
CA2618349C (en) * 2005-08-11 2016-05-31 Massachusetts Institute Of Technology Intravesical drug delivery device and method
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
US7989442B2 (en) 2006-09-27 2011-08-02 N.V. Organon Progesterone receptor modulators
AU2007324467A1 (en) * 2006-11-22 2008-05-29 N.V. Organon Vaginal delivery system for mirtazapine
TW200840595A (en) * 2006-12-12 2008-10-16 Organon Nv Oral contraceptive spray
US8063037B2 (en) 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
TW200930343A (en) * 2007-09-21 2009-07-16 Organon Nv Drug delivery system
JP5560200B2 (ja) * 2007-12-11 2014-07-23 マサチューセッツ インスチテュート オブ テクノロジー 膀胱および他の身体の小嚢又は管腔を治療するための埋め込み型薬物供給デバイス
KR101794899B1 (ko) * 2008-08-09 2017-11-07 메사츄세츠 인스티튜트 어브 테크놀로지 남성 비뇨생식기 및 주위 조직을 치료하는 방법 및 체내이식형 약물 전달 장치
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
WO2010054296A2 (en) * 2008-11-07 2010-05-14 Combinent Biomedical Systems, Inc. Devices and methods for treating and/or preventing diseases
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
CA2755828A1 (en) 2009-03-17 2010-09-23 Intervet International B.V. Zoo-technical drug delivery device
MX2011010607A (es) 2009-04-07 2012-04-02 Catholic Healthcare West Sistema y metodo de estimulacion electrica uterina.
US8568374B2 (en) * 2009-05-04 2013-10-29 Merck Sharp & Dohme B.V. Intrauterine system
EP4108216A1 (en) 2009-06-03 2022-12-28 Forsight Vision5, Inc. Anterior segment drug delivery
AU2010265863C1 (en) 2009-06-26 2012-11-01 Taris Biomedical Llc Implantable drug delivery devices and methods of making the same
MX2012000948A (es) 2009-07-21 2012-02-28 Population Council Inc Anillo vaginal gradiente multicapas.
US9017312B2 (en) * 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US20110236462A1 (en) * 2010-03-28 2011-09-29 Shaked Ze Ev Intravaginal drug delivery device
WO2011156674A2 (en) 2010-06-10 2011-12-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
EP3378391B1 (en) 2010-10-27 2020-12-02 Dignity Health Uterine electrical stimulation system
US9872983B2 (en) 2010-10-27 2018-01-23 Dignity Health Uterine electrical stimulation system and method
US9114111B2 (en) 2011-01-10 2015-08-25 Allergan, Inc. Methods for sustained treatment of bladder pain and irritative voiding
KR101263916B1 (ko) 2011-01-11 2013-05-13 이장희 성 호르몬 방출 장치 및 이를 이용한 동물 피임 및 발정 유도 방법
JP6043730B2 (ja) * 2011-02-04 2016-12-14 タリス バイオメディカル エルエルシー 低溶解性薬物の制御された放出のための植込み型装置
CN103796708A (zh) * 2011-07-20 2014-05-14 帕特里克.F.凯瑟 用于递送药物的阴道内装置
WO2013029194A1 (es) 2011-08-26 2013-03-07 Universidad De Santiago De Chile Uso de los anti-inflamatorios no esteroidales meloxicam y piroxicam, por via intravaginal, para la interrupción del proceso ovulatorio en la mujer
TR201808748T4 (tr) 2012-09-03 2018-07-23 Ecosea Farming S A Hidrobiyolojik türlerin kültürü ve/veya korunmasına yönelik rezervuar-kafes daldırma sistemi.
HK1207588A1 (en) 2012-11-22 2016-02-05 Bayer Pharma Aktiengesellschaft Use and application regimen of a pharmaceutical composition containing levonorgestrel and a cox inhibitor for on-demand contraception
DK2964088T3 (da) 2013-03-08 2023-06-06 Li Galli B V I O Vaginalt lægemiddeladministrations- og/eller diagnosesystem
DK2968880T3 (da) 2013-03-15 2025-05-19 Taris Biomedical Llc Lægemiddelafgivelsesindretninger med lægemiddelpermeabel komponent
LT3035991T (lt) 2013-08-19 2020-11-10 Taris Biomedical Llc Daugiablokiai vaistų vartojimo įtaisai
WO2015035003A1 (en) 2013-09-05 2015-03-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) * 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
US10918515B2 (en) 2015-03-31 2021-02-16 Merck Sharp & Dohme B.V. Vaginal ring applicator
WO2016168141A1 (en) 2015-04-13 2016-10-20 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
WO2016172704A1 (en) 2015-04-23 2016-10-27 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
CA2985717A1 (en) 2015-05-13 2016-11-17 Bayer Oy A long acting drug delivery device and its use in contraception
EP3272333A1 (en) 2016-07-22 2018-01-24 Chemo Research, S.L. Vaginal composition comprising a combination of estrogen and vitamin d
EP3395335A1 (en) 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginal ring for the simultaneous release of two active ingredients
DE102017113166A1 (de) * 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
US11103460B2 (en) 2017-08-07 2021-08-31 Board Of Regents, The University Of Texas System Fabrication methods for nanodelivery systems for long term controlled delivery of active pharmaceutical ingredients
WO2019222856A1 (en) 2018-05-24 2019-11-28 Nureva Inc. Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
CA3087238A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
BR112020023982A2 (pt) 2018-05-24 2021-02-23 Celanese Eva Performance Polymers Llc dispositivo implantável para liberação prolongada de um composto de fármaco macromolecular
MX2021006426A (es) * 2018-12-11 2021-09-14 Lupin Inc Sistema de suministro de farmaco para combinaciones de estrogeno de dosis ultra-baja y metodos y usos del mismo.
US20230404911A1 (en) * 2018-12-11 2023-12-21 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
US10632066B1 (en) 2019-02-01 2020-04-28 The Population Council, Inc. Method of providing birth control
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
US11529308B2 (en) 2019-06-21 2022-12-20 The Population Council, Inc. System for providing birth control
US11439588B2 (en) 2019-10-12 2022-09-13 National Research Institute For Family Planning Vaginal sustained-release drug delivery system for luteal support, method for preparation and use thereof
CN114980861A (zh) 2019-11-27 2022-08-30 橡冠科学研究院 缓释药物递送装置
USD935018S1 (en) 2020-04-07 2021-11-02 The Population Council, Inc. Contraceptive
BR112023022439A2 (pt) 2021-04-26 2023-12-26 Celanese Eva Performance Polymers Llc Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular
IL314036A (en) 2022-01-06 2024-09-01 Oak Crest Inst Of Science Subdermal implant for sustained drug delivery
EP4215181A1 (en) * 2022-01-21 2023-07-26 Sever Pharma Solutions An intravaginal ring
EP4626399A1 (en) 2022-12-02 2025-10-08 VaRi Bioscience GmbH Estriol vaginal ring
AU2024256750A1 (en) 2023-04-19 2025-10-23 Oak Crest Institute Of Science Vaginal drug delivery device

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
ZA857643B (en) * 1984-10-12 1986-05-28 Akzo Nv Release system for two or more active substances
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
ES2054784T3 (es) * 1987-08-08 1994-08-16 Akzo Nv Un metodo para la fabricacion de un implante.
JPH03123727A (ja) * 1989-10-04 1991-05-27 Nitto Denko Corp 経皮吸収製剤
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
NZ262679A (en) * 1993-02-22 1997-08-22 Vivorx Pharmaceuticals Inc Compositions for in vivo delivery of pharmaceutical agents where the agents are contained in a polymeric shell
US5543150A (en) * 1993-09-15 1996-08-06 Columbia Laboratories, Inc. Method of progesterone delivery and affect thereof
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
FR2717688B1 (fr) * 1994-03-28 1996-07-05 Lhd Lab Hygiene Dietetique Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base d'EVA.
EP0836473B1 (en) * 1995-07-04 2001-10-31 Akzo Nobel N.V. Ring-shaped devices
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
TW358031B (en) * 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances

Also Published As

Publication number Publication date
HU222343B1 (hu) 2003-06-28
DE69803112T2 (de) 2002-07-18
ZA982911B (en) 1998-10-09
NO981638D0 (no) 1998-04-08
BR9801027B1 (pt) 2009-01-13
ID21259A (id) 1999-05-12
PT876815E (pt) 2002-07-31
NO981638L (no) 1998-10-12
ES2171283T3 (es) 2002-09-01
EP0876815B1 (en) 2002-01-09
IL123813A0 (en) 1998-10-30
CA2233753C (en) 2001-12-25
CA2233753A1 (en) 1998-10-11
EP0876815A1 (en) 1998-11-11
RU2206325C2 (ru) 2003-06-20
CZ110298A3 (cs) 1998-10-14
US5989581A (en) 1999-11-23
HU9800863D0 (en) 1998-05-28
KR100492676B1 (ko) 2005-10-19
BR9801027A (pt) 2000-01-11
DK0876815T3 (da) 2002-04-22
CN1163222C (zh) 2004-08-25
PL325774A1 (en) 1998-10-12
SG65061A1 (en) 1999-05-25
CN1196930A (zh) 1998-10-28
DE69803112D1 (de) 2002-02-14
HK1016886A1 (en) 1999-11-12
NZ330145A (en) 1999-05-28
IL123813A (en) 2001-11-25
TR199800648A1 (xx) 1998-10-21
AU726934B2 (en) 2000-11-23
CZ294099B6 (cs) 2004-10-13
JP2009256378A (ja) 2009-11-05
KR19980081290A (ko) 1998-11-25
TW358031B (en) 1999-05-11
HUP9800863A3 (en) 2000-06-28
AU6075198A (en) 1998-10-15
JPH10287549A (ja) 1998-10-27
NO320394B1 (no) 2005-11-28
PL192449B1 (pl) 2006-10-31
JP4982670B2 (ja) 2012-07-25
ATE211646T1 (de) 2002-01-15
HUP9800863A2 (hu) 1999-02-01

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