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MX2012000948A - Anillo vaginal gradiente multicapas. - Google Patents

Anillo vaginal gradiente multicapas.

Info

Publication number
MX2012000948A
MX2012000948A MX2012000948A MX2012000948A MX2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A MX 2012000948 A MX2012000948 A MX 2012000948A
Authority
MX
Mexico
Prior art keywords
pharmaceutically active
layers
vaginal ring
disclosed
active ingredient
Prior art date
Application number
MX2012000948A
Other languages
English (en)
Inventor
Bruce Variano
Jeffrey Speck
Maria Teresa Sallent
Simone Evans
Original Assignee
Population Council Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Population Council Inc filed Critical Population Council Inc
Publication of MX2012000948A publication Critical patent/MX2012000948A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Se describen anillos vaginales multicapas 2 que comprenden elastómeros de silicona e ingredientes farmacéuticamente activos. Los anillos comprenden un cierto número de capas, al menos una de las cuales contiene un ingrediente farmacéuticamente activo, y cada una de las cuales es un elastómero de silicona. Preferentemente, las múltiples capas se producen a partir de estas capas de diferentes composiciones, que incluyen una capa interior 4, una capa intermedia 5, y una capa exterior 6. Sin embargo, después de la extrusión y de la curación simultánea, el anillo 2 incluye un cuerpo contiguo el cual comprende un cuerpo continuo de silicona que proporciona la libre difusión del ingrediente farmacéuticamente activo desde la(s) capa(s) interior(es) 4 hacia la(s) capa(s) exterior(es) 6. También se describen los métodos para producir estos anillos vaginales y el uso de los mismos.
MX2012000948A 2009-07-21 2010-04-07 Anillo vaginal gradiente multicapas. MX2012000948A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27139109P 2009-07-21 2009-07-21
PCT/US2010/030183 WO2011011099A1 (en) 2009-07-21 2010-04-07 Multi-layered gradient vaginal ring

Publications (1)

Publication Number Publication Date
MX2012000948A true MX2012000948A (es) 2012-02-28

Family

ID=42236498

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012000948A MX2012000948A (es) 2009-07-21 2010-04-07 Anillo vaginal gradiente multicapas.

Country Status (14)

Country Link
US (1) US8753667B2 (es)
EP (1) EP2456421B1 (es)
JP (1) JP5690826B2 (es)
CN (1) CN102497855B (es)
AU (1) AU2010274946B2 (es)
BR (1) BR112012001353B8 (es)
CA (1) CA2767967C (es)
CO (1) CO6491080A2 (es)
DK (1) DK2456421T3 (es)
ES (1) ES2626156T3 (es)
IN (1) IN2012DN00711A (es)
MX (1) MX2012000948A (es)
WO (1) WO2011011099A1 (es)
ZA (1) ZA201200809B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
DE202011110355U1 (de) * 2011-03-09 2014-01-15 Arstat, Inc. Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
FR3005417B1 (fr) * 2013-05-10 2015-05-22 Blaise Francois Figuereo Anneau vaginal tri-reservoir, a retro-largage compatible avec les caracteristiques des molecules actives qu'il contient
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015198104A1 (es) 2014-06-28 2015-12-30 Laboratorios Andromaco S.A. Pesario de cerclaje que contiene progesterona de liberación prolongada, sostenida y continua, útil para la prevención de parto prematuro
US9943146B2 (en) 2015-05-27 2018-04-17 Qalo Llc Compression molded silicone ring
EP3316724B1 (en) * 2015-07-14 2019-09-11 Qalo LLC Compression molding a silicone ring
CA3008941C (en) * 2015-12-21 2024-01-02 Bayer Oy Method for manufacturing a drug delivery device and a drug delivery device manufactured according to the method
EP3272333A1 (en) 2016-07-22 2018-01-24 Chemo Research, S.L. Vaginal composition comprising a combination of estrogen and vitamin d
CN106913412B (zh) * 2017-03-01 2023-09-22 上海市嘉定区妇幼保健院 易放易取式子宫托
EP3803866A4 (en) 2018-05-24 2022-03-16 Nureva Inc. METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
US11690807B2 (en) 2018-05-24 2023-07-04 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
AU2019275409B2 (en) 2018-05-24 2024-08-15 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
EP4057994A4 (en) * 2019-11-12 2023-12-06 Poly-Med Inc. Contraceptive medical devices
DE102021100916A1 (de) 2021-01-18 2022-07-21 Carl Freudenberg Kg Verfahren zur Herstellung eines Bauteils, Werkzeug zur Durchführung des Verfahrens und Bauteil, das durch das Verfahren hergestellt ist
EP4329734A4 (en) 2021-04-26 2025-04-02 Celanese EVA Performance Polymers LLC Implantable device for the delayed release of a macromolecular drug compound

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL152819B (nl) 1949-04-07 Swift & Co Werkwijze voor het continu bereiden van mono-ammoniumdiwaterstoffosfaatdeeltjes en zo verkregen deeltjes.
US2863846A (en) 1950-05-04 1958-12-09 Dow Corning Organo silyl-silica filled siloxane elastomers and process for producing same
US2890188A (en) 1951-12-17 1959-06-09 Dow Corning Siloxane elastomers compounded with hydroxylated silanes
NL91756C (es) 1953-11-19
GB804199A (en) 1955-12-22 1958-11-12 Midland Silicones Ltd Organosiloxane compositions
GB798669A (en) 1956-12-12 1958-07-23 Midland Silicones Ltd Improvements in or relating to organosiloxane elastomer foams
US2927907A (en) 1957-01-07 1960-03-08 Dow Corning Siloxane elastomers
US3022951A (en) 1957-05-14 1962-02-27 Ibm Full adder
US3035016A (en) 1959-03-16 1962-05-15 Dow Corning Acyloxy siloxanes and a method of using the
US3545439A (en) 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US4155991A (en) 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
IL48277A (en) 1974-10-18 1978-03-10 Schering Ag Vaginal ring
US3995633A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal Medicament dispensing device
US3995634A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal cavity dispensing means and method
US4237885A (en) 1978-10-23 1980-12-09 Alza Corporation Delivery system with mated members for storing and releasing a plurality of beneficial agents
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
DE3040978A1 (de) 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
EP0180264A1 (en) 1984-10-12 1986-05-07 Akzo N.V. Release system for two or more active substances
FR2598652B1 (fr) 1986-05-16 1988-08-05 Figuereo Blaise Machine d'extrusion simultanee de plusieurs matieres
US4922928A (en) 1988-08-17 1990-05-08 Michael Burnhill Vaginal device
US6544546B1 (en) 1995-07-04 2003-04-08 Akzo Nobel, N.V. Ring-shaped devices
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
IL123813A0 (en) 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6951654B2 (en) 2001-03-27 2005-10-04 Galen (Chemicals) Limited Intravaginal drug delivery devices for the administration of an antimicrobial agent
US7833545B2 (en) 2003-04-29 2010-11-16 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
TWI336627B (en) * 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US7824383B2 (en) 2006-06-16 2010-11-02 Family Health International Vaginal drug delivery system and method

Also Published As

Publication number Publication date
US20120148655A1 (en) 2012-06-14
BR112012001353B8 (pt) 2021-05-25
AU2010274946A1 (en) 2012-03-01
CO6491080A2 (es) 2012-07-31
AU2010274946B2 (en) 2013-09-12
US8753667B2 (en) 2014-06-17
CA2767967A1 (en) 2011-01-27
CN102497855B (zh) 2013-12-25
EP2456421A1 (en) 2012-05-30
IN2012DN00711A (es) 2015-06-19
CN102497855A (zh) 2012-06-13
CA2767967C (en) 2014-10-21
EP2456421B1 (en) 2017-04-05
BR112012001353A2 (pt) 2016-04-05
DK2456421T3 (en) 2017-06-06
BR112012001353B1 (pt) 2020-04-14
JP2012533401A (ja) 2012-12-27
WO2011011099A1 (en) 2011-01-27
ES2626156T3 (es) 2017-07-24
ZA201200809B (en) 2012-10-31
JP5690826B2 (ja) 2015-03-25
HK1169614A1 (en) 2013-02-01

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