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AR005152A1 - Amidas tricíclicas útiles para la inhibición de la función de la proteina-g, sus sales , una composición farmacéutica que las contienen y el uso de las mismas para la fabricación de un medicamento para el tratamiento de enfermedades proliferativas - Google Patents

Amidas tricíclicas útiles para la inhibición de la función de la proteina-g, sus sales , una composición farmacéutica que las contienen y el uso de las mismas para la fabricación de un medicamento para el tratamiento de enfermedades proliferativas

Info

Publication number
AR005152A1
AR005152A1 ARP960105785A ARP960105785A AR005152A1 AR 005152 A1 AR005152 A1 AR 005152A1 AR P960105785 A ARP960105785 A AR P960105785A AR P960105785 A ARP960105785 A AR P960105785A AR 005152 A1 AR005152 A1 AR 005152A1
Authority
AR
Argentina
Prior art keywords
inhibition
protein
manufacture
treatment
pharmaceutical composition
Prior art date
Application number
ARP960105785A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AR005152A1 publication Critical patent/AR005152A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Se revelan compuestos derivados de amidas triciclicas, tales como formulas A, B, C, D, E, F, utiles para la inhibicion de la funcion de la proteina -G ypara el tratamiento delas enfermedades proliferativas, una composicion farmaceutica quelas contienen, y el uso de las mismas para la fabricacion deun medicamento.
ARP960105785A 1995-12-22 1996-12-19 Amidas tricíclicas útiles para la inhibición de la función de la proteina-g, sus sales , una composición farmacéutica que las contienen y el uso de las mismas para la fabricación de un medicamento para el tratamiento de enfermedades proliferativas AR005152A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57795195A 1995-12-22 1995-12-22
US61576096A 1996-03-13 1996-03-13

Publications (1)

Publication Number Publication Date
AR005152A1 true AR005152A1 (es) 1999-04-14

Family

ID=27077386

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105785A AR005152A1 (es) 1995-12-22 1996-12-19 Amidas tricíclicas útiles para la inhibición de la función de la proteina-g, sus sales , una composición farmacéutica que las contienen y el uso de las mismas para la fabricación de un medicamento para el tratamiento de enfermedades proliferativas

Country Status (23)

Country Link
EP (2) EP1380581A1 (es)
JP (1) JP3193725B2 (es)
KR (1) KR100295224B1 (es)
CN (1) CN1326847C (es)
AR (1) AR005152A1 (es)
AT (1) ATE309238T1 (es)
AU (1) AU730194B2 (es)
BR (1) BR9612203A (es)
CA (2) CA2240846C (es)
CZ (1) CZ292791B6 (es)
DE (1) DE69635424T2 (es)
DK (1) DK1019392T3 (es)
ES (1) ES2248826T3 (es)
HU (1) HU228352B1 (es)
IL (1) IL125062A (es)
MX (1) MX9804956A (es)
MY (1) MY119007A (es)
NO (1) NO318232B1 (es)
NZ (1) NZ326035A (es)
PL (1) PL185597B1 (es)
SK (1) SK86198A3 (es)
TW (1) TW350844B (es)
WO (1) WO1997023478A1 (es)

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IL117798A (en) * 1995-04-07 2001-11-25 Schering Plough Corp Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them

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NZ326035A (en) 2000-01-28
CZ292791B6 (cs) 2003-12-17
CZ193898A3 (cs) 1998-10-14
MY119007A (en) 2005-03-31
KR100295224B1 (ko) 2001-09-17
WO1997023478A1 (en) 1997-07-03
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JP3193725B2 (ja) 2001-07-30
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CA2358394A1 (en) 1997-07-03
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CA2240846A1 (en) 1997-07-03
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