AP2037A - Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases - Google Patents

Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases

Info

Publication number: AP2037A
Authority: AP; ARIPO
Prior art keywords: treatment; drug resistant; quinoline derivatives; substituted quinoline; mycobacterial diseases
Prior art date: 2004-05-28

Application number

AP2006003828A

Other languages

English (en)

Other versions

AP2006003828A0 (en

Inventor

Koenraad Jozef Lodewijkmarcel Andries

Gestel Jozef Frans Elisabetha Van

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-28

Filing date

2005-05-24

Publication date

2009-10-09

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34929150&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2037(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-05-24 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2006-12-31 Publication of AP2006003828A0 publication Critical patent/AP2006003828A0/xx

2009-10-09 Application granted granted Critical

2009-10-09 Publication of AP2037A publication Critical patent/AP2037A/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AP2006003828A 2004-05-28 2005-05-24 Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases AP2037A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP04102402		2004-05-28
PCT/EP2005/052371 WO2005117875A1 (en)	2004-05-28	2005-05-24	Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases

Publications (2)

Publication Number	Publication Date
AP2006003828A0 AP2006003828A0 (en)	2006-12-31
AP2037A true AP2037A (en)	2009-10-09

Family

ID=34929150

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2006003828A AP2037A (en)	2004-05-28	2005-05-24	Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases

Country Status (34)

Country	Link
US (2)	US20070249667A1 (ru)
EP (1)	EP1753427B1 (ru)
JP (2)	JP5081617B2 (ru)
KR (2)	KR101371653B1 (ru)
CN (2)	CN102908347A (ru)
AP (1)	AP2037A (ru)
AR (1)	AR049127A1 (ru)
AT (1)	ATE390925T1 (ru)
AU (1)	AU2005249231B2 (ru)
BR (1)	BRPI0510414B1 (ru)
CA (1)	CA2566544C (ru)
CL (1)	CL2009001980A1 (ru)
CY (1)	CY1110388T1 (ru)
DE (1)	DE602005005810T2 (ru)
DK (1)	DK1753427T3 (ru)
EA (1)	EA010651B1 (ru)
ES (1)	ES2306146T3 (ru)
HR (1)	HRP20080307T3 (ru)
IL (1)	IL179630A (ru)
JO (1)	JO2524B1 (ru)
ME (1)	ME01105B (ru)
MX (1)	MXPA06013888A (ru)
MY (1)	MY140611A (ru)
NO (1)	NO338624B1 (ru)
NZ (1)	NZ550840A (ru)
PA (1)	PA8635201A1 (ru)
PL (1)	PL1753427T3 (ru)
PT (1)	PT1753427E (ru)
RS (1)	RS50585B (ru)
SI (1)	SI1753427T1 (ru)
TW (1)	TWI363625B (ru)
UA (1)	UA90267C2 (ru)
WO (1)	WO2005117875A1 (ru)
ZA (1)	ZA200609899B (ru)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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ATE390925T1 (de) *	2004-05-28	2008-04-15	Janssen Pharmaceutica Nv	Verwendung von substituierten chinolin-derivaten zur behandlung von arzneimittelresistenten mycobakteriellen erkrankungen
KR101301573B1 (ko) *	2004-12-24	2013-09-04	얀센 파마슈티카 엔.브이.	잠재성 튜버큐로시스의 치료법
EE05697B1 (et) *	2005-06-08	2014-02-17	Janssen Pharmaceutica N.V.	Kinoliini derivaadid kui antibakteriaalsed toimeained
JP5349730B2 (ja) *	2005-06-09	2013-11-20	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	抗バクテリア剤としてのキノリン誘導体
JO2752B1 (en) *	2005-06-28	2014-03-15	شركة جانسين فارماسوتيكا ان. في	Quinoline derivatives acting as antibacterial agents
NZ564340A (en) *	2005-06-28	2011-02-25	Janssen Pharmaceutica Nv	Quinoline derivatives as antibacterial agents
JO3270B1 (ar) *	2005-06-28	2018-09-16	Janssen Pharmaceutica Nv	مشتقات كوينولين بصفة عوامل مضادة للبكتيريا
US8686002B2 (en)	2005-08-21	2014-04-01	AbbVie Deutschland GmbH & Co. KG	Heterocyclic compounds and their use as binding partners for 5-HT5 receptors
UA97813C2 (ru) *	2006-12-05	2012-03-26	Янссен Фармацевтика Н.В.	Фумаратная соль (альфа s, бета r)-6-бром-альфа-[2-(диметиламино)этил]-2-метокси-альфа-1-нафталенил-бета-фенил-3-хинолинэтанола
JO2683B1 (en) *	2006-12-06	2013-03-03	جانسين فارماسوتيكا ان. في	Quinoline antibacterial derivatives
JO3271B1 (ar) *	2006-12-06	2018-09-16	Janssen Pharmaceutica Nv	مشتقات الكوينولين المضادة للجراثيم
JO2685B1 (en)	2006-12-06	2013-03-03	جانسين فارماسوتيكا ان في	Quinoline antibacterial derivatives
JO2725B1 (en) *	2006-12-06	2013-09-15	جانسين فارماسوتيكا ان. في	Quinoline antibacterial derivatives
JO2684B1 (en) *	2006-12-06	2013-03-03	جانسين فارماسوتيكا ان في	Quinoline antibacterial derivatives
JO2970B1 (en) *	2006-12-06	2016-03-15	جانسين فارماسوتيكا ان. في	Quinoline antibacterial derivatives
MD4009C2 (ru) *	2008-07-15	2010-08-31	Институт Химии Академии Наук Молдовы	Использование 1-метил-4-(N-метиламинобутил-4)-β-карболина в качестве противотуберкулезного средства
RU2404971C2 (ru) *	2008-12-02	2010-11-27	ЗАО "Фарм-Синтез"	Новые производные хинолина, способ их получения, их применение для лечения микобактериальных инфекций, фармацевтическая композиция на их основе
JP2013504591A (ja) *	2009-09-11	2013-02-07	バーテックスファーマシューティカルズインコーポレイテッド	Ｎ−ベンジル−３−（４−クロロフェニル）−２−［メチル−［２−オキソ−２−（３，４，５−トリメトキシフェニル）アセチル］アミノ］−ｎ−［３−（４−ピリジル）−１−［２−（４−ピリジル）エチル］プロピル］プロパンアミドの組成物およびその使用
CN102249935B (zh)	2010-05-17	2015-05-20	中国人民解放军军事医学科学院毒物药物研究所	芳香2-丁醇类化合物及其医药用途
WO2013160435A1 (en)	2012-04-27	2013-10-31	Janssen Pharmaceutica Nv	Antibacterial quinoline derivatives
WO2013160431A1 (en)	2012-04-27	2013-10-31	Janssen Pharmaceutica Nv	Antibacterial quinoline derivatives
CN105330595B (zh) *	2014-07-14	2019-12-10	上海嘉坦医药科技有限公司	吡啶衍生物及其作为抗分支杆菌的应用
CA2954872C (en) *	2014-07-14	2019-08-13	Cisen Pharmaceutical Co., Ltd.	Pyridine derivatives and anti-mycobacterial use thereof
US20180000810A1 (en)	2015-01-27	2018-01-04	Janssen Pharmaceutica Nv	Dispersible compositions
CN106279017A (zh) *	2015-05-21	2017-01-04	重庆圣华曦药业股份有限公司	贝达喹啉晶型、组合物及其制备方法
US10196360B2 (en)	2015-10-20	2019-02-05	Zhejiang Hisun Pharmaceutical Co., Ltd.	Crystal forms of bedaquiline fumarate and preparation methods therefor
WO2017121323A1 (zh) *	2016-01-13	2017-07-20	辰欣药业股份有限公司	一种吡啶衍生物类化合物的制备方法及其中间体和晶型
US10508097B2 (en) *	2016-03-07	2019-12-17	The Global Alliance For Tb Drug Development, Inc.	Antibacterial compounds and uses thereof
CN107243008B (zh) *	2017-04-13	2021-03-30	中国科学院广州生物医药与健康研究院	吡唑并[1,5-a]吡啶类化合物的新应用及一种治疗脓肿分枝杆菌感染的组合物
EP3677687A4 (en) *	2017-09-01	2021-05-26	The Kitasato Institute	NEW COMPOSITION WITH THERAPEUTIC EFFECT AGAINST INFECTIONS DUE TO THE MYCOBACTERIUM-AVIUM COMPLEX AND THE PROCESS FOR THEIR PRODUCTION
WO2020047596A1 (en) *	2018-09-04	2020-03-12	Monash University	Antibacterial compounds and methods of use
CN113271930A (zh)	2019-01-09	2021-08-17	詹森药业有限公司	治疗非结核分枝杆菌疾病的组合
WO2021107876A1 (en) *	2019-11-26	2021-06-03	Nanyang Technological University	Compounds for treating tuberculosis
CN110804016B (zh) *	2019-12-05	2022-11-04	福建省微生物研究所	抗结核分枝杆菌的二芳基喹啉衍生物
EP4243800A1 (en)	2020-11-12	2023-09-20	JANSSEN Pharmaceutica NV	Combination of bedaquiline, ethambutol and a macrolide in the treatment of nontuberculous mycobacterial diseases
WO2023217279A1 (zh) *	2022-05-13	2023-11-16	广州嘉越医药科技有限公司	一种吡啶衍生物、中间体、制备方法和应用
WO2023227123A1 (zh) *	2022-05-27	2023-11-30	广州嘉越医药科技有限公司	吡啶衍生物的用途
WO2023232838A1 (en)	2022-05-31	2023-12-07	Janssen Pharmaceutica Nv	Bedaquiline for use in the treatment of leprosy
CN120225518A (zh) *	2022-11-15	2025-06-27	伊莱利利公司	Ahr激动剂
WO2025068448A1 (en)	2023-09-28	2025-04-03	Janssen Pharmaceutica Nv	Atp synthase inhibitors for use in the treatment of non-tuberculosis mycobacteria

Citations (1)

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WO2004011436A1 (en) *	2002-07-25	2004-02-05	Janssen Pharmaceutica N.V.	Quinoline derivatives and their use as mycobacterial inhibitors

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CA2270123A1 (en) *	1996-10-28	1998-05-07	Department Of The Army, U.S. Government	Compounds, compositions and methods for treating antibiotic-resistant infections
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ATE390925T1 (de) *	2004-05-28	2008-04-15	Janssen Pharmaceutica Nv	Verwendung von substituierten chinolin-derivaten zur behandlung von arzneimittelresistenten mycobakteriellen erkrankungen
EE05697B1 (et) *	2005-06-08	2014-02-17	Janssen Pharmaceutica N.V.	Kinoliini derivaadid kui antibakteriaalsed toimeained

2005
- 2005-05-24 AT AT05743054T patent/ATE390925T1/de active
- 2005-05-24 SI SI200530294T patent/SI1753427T1/sl unknown
- 2005-05-24 JP JP2007513922A patent/JP5081617B2/ja not_active Expired - Lifetime
- 2005-05-24 EP EP05743054A patent/EP1753427B1/en not_active Expired - Lifetime
- 2005-05-24 HR HR20080307T patent/HRP20080307T3/xx unknown
- 2005-05-24 NZ NZ550840A patent/NZ550840A/en not_active IP Right Cessation
- 2005-05-24 WO PCT/EP2005/052371 patent/WO2005117875A1/en not_active Ceased
- 2005-05-24 DK DK05743054T patent/DK1753427T3/da active
- 2005-05-24 CN CN2012103943126A patent/CN102908347A/zh active Pending
- 2005-05-24 CA CA2566544A patent/CA2566544C/en not_active Expired - Lifetime
- 2005-05-24 US US11/569,681 patent/US20070249667A1/en not_active Abandoned
- 2005-05-24 KR KR1020067024974A patent/KR101371653B1/ko not_active Expired - Lifetime
- 2005-05-24 KR KR1020137002606A patent/KR20130024969A/ko not_active Ceased
- 2005-05-24 ME MEP-2008-89A patent/ME01105B/me unknown
- 2005-05-24 CN CN2005800170162A patent/CN1976704B/zh not_active Expired - Fee Related
- 2005-05-24 RS RSP-2008/0291A patent/RS50585B/sr unknown
- 2005-05-24 UA UAA200611048A patent/UA90267C2/ru unknown
- 2005-05-24 EA EA200602260A patent/EA010651B1/ru active Protection Beyond IP Right Term
- 2005-05-24 JO JO200574A patent/JO2524B1/en active
- 2005-05-24 AU AU2005249231A patent/AU2005249231B2/en not_active Expired
- 2005-05-24 MX MXPA06013888A patent/MXPA06013888A/es active IP Right Grant
- 2005-05-24 PL PL05743054T patent/PL1753427T3/pl unknown
- 2005-05-24 DE DE602005005810T patent/DE602005005810T2/de not_active Expired - Lifetime
- 2005-05-24 PT PT05743054T patent/PT1753427E/pt unknown
- 2005-05-24 BR BRPI0510414-9A patent/BRPI0510414B1/pt not_active IP Right Cessation
- 2005-05-24 ES ES05743054T patent/ES2306146T3/es not_active Expired - Lifetime
- 2005-05-24 AP AP2006003828A patent/AP2037A/xx active
- 2005-05-27 MY MYPI20052432A patent/MY140611A/en unknown
- 2005-05-27 PA PA20058635201A patent/PA8635201A1/es unknown
- 2005-05-27 TW TW094117334A patent/TWI363625B/zh not_active IP Right Cessation
- 2005-05-27 AR ARP050102200A patent/AR049127A1/es unknown
2006
- 2006-11-27 IL IL179630A patent/IL179630A/en active IP Right Grant
- 2006-11-27 ZA ZA200609899A patent/ZA200609899B/xx unknown
- 2006-12-28 NO NO20066041A patent/NO338624B1/no unknown
2008
- 2008-07-02 CY CY20081100696T patent/CY1110388T1/el unknown
2009
- 2009-10-20 CL CL2009001980A patent/CL2009001980A1/es unknown
2010
- 2010-03-08 US US12/719,221 patent/US20100168133A1/en not_active Abandoned
2012
- 2012-07-06 JP JP2012152373A patent/JP5675718B2/ja not_active Expired - Lifetime

Patent Citations (1)

* Cited by examiner, † Cited by third party
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WO2004011436A1 (en) *	2002-07-25	2004-02-05	Janssen Pharmaceutica N.V.	Quinoline derivatives and their use as mycobacterial inhibitors

Also Published As

Publication number	Publication date
DK1753427T3 (da)	2008-07-21
EP1753427B1 (en)	2008-04-02
UA90267C2 (ru)	2010-04-26
MXPA06013888A (es)	2007-01-26
CN102908347A (zh)	2013-02-06
CA2566544A1 (en)	2005-12-15
KR20130024969A (ko)	2013-03-08
EA200602260A1 (ru)	2007-04-27
CY1110388T1 (el)	2015-04-29
MY140611A (en)	2009-12-31
ATE390925T1 (de)	2008-04-15
EA010651B1 (ru)	2008-10-30
EP1753427A1 (en)	2007-02-21
BRPI0510414A (pt)	2007-10-23
US20100168133A1 (en)	2010-07-01
PA8635201A1 (es)	2006-05-16
CN1976704B (zh)	2012-12-05
AR049127A1 (es)	2006-06-28
NO20066041L (no)	2007-02-27
DE602005005810D1 (de)	2008-05-15
CA2566544C (en)	2012-04-17
JP5081617B2 (ja)	2012-11-28
ME01105B (me)	2013-03-20
TW200608974A (en)	2006-03-16
CN1976704A (zh)	2007-06-06
JP2012229239A (ja)	2012-11-22
AU2005249231B2 (en)	2010-11-11
IL179630A0 (en)	2007-07-04
TWI363625B (en)	2012-05-11
AP2006003828A0 (en)	2006-12-31
JP5675718B2 (ja)	2015-02-25
SI1753427T1 (sl)	2008-10-31
PL1753427T3 (pl)	2008-09-30
ZA200609899B (en)	2009-01-28
BRPI0510414B1 (pt)	2022-04-05
HRP20080307T3 (hr)	2008-07-31
WO2005117875A1 (en)	2005-12-15
JO2524B1 (en)	2010-03-17
IL179630A (en)	2011-05-31
HK1106136A1 (en)	2008-03-07
JP2008500992A (ja)	2008-01-17
DE602005005810T2 (de)	2009-04-09
AU2005249231A1 (en)	2005-12-15
KR20070017393A (ko)	2007-02-09
US20070249667A1 (en)	2007-10-25
RS50585B (sr)	2010-05-07
CL2009001980A1 (es)	2010-04-16
ES2306146T3 (es)	2008-11-01
NZ550840A (en)	2010-01-29
KR101371653B1 (ko)	2014-03-07
PT1753427E (pt)	2008-07-04
NO338624B1 (no)	2016-09-19

Publication	Publication Date	Title
AP2037A (en)	2009-10-09	Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
HUE050998T2 (hu)	2021-01-28	Gyógyszerek fibrotikus betegségek kezelésére
PL1888548T3 (pl)	2013-01-31	Pochodna chinoliny do leczenia schorzeń siatkówki
HUS1500058I1 (hu)	2016-01-28	Benzoxazint tartalmazó gyógyszer-kombináció légúti betegségek kezelésére
GB0312832D0 (en)	2003-07-09	2-amino-pyridine derivatives useful for the treatment of diseases
IL184123A0 (en)	2008-12-29	Quinoline derivatives for the treatment of latent tuberculosis
IL184934A0 (en)	2007-12-03	4-oxoquinazoline-3-yl-benzamide derivatives for the treatment of cytokine diseases
IL176629A0 (en)	2006-10-31	Sulfonamide derivatives for the treatment of diseases
AP2006003669A0 (en)	2006-06-30	Sulfonamide derivatives for the treatment of diseases
IL184124A0 (en)	2007-10-31	Medicaments for the treatment or prevention of fibrotic diseases
ZA200705160B (en)	2008-09-25	Quinoline derivatives for the treatment of latent tuberculosis
ZA200606780B (en)	2008-08-27	Compounds for the treatment of diseases
GB0425054D0 (en)	2004-12-15	Formamide derivatives for the treatment of diseases
GB0408297D0 (en)	2004-05-19	Indole derivatives for the treatment of diseases
GB0312840D0 (en)	2003-07-09	2-amino-pyridine derivatives useful for the treatment of diseases
GB0312842D0 (en)	2003-07-09	2-amino-pyridine derivatives useful for the treatment of diseases
GB0406387D0 (en)	2004-04-21	Sulfonamide derivatives for the treatment of diseases
IL176564A0 (en)	2006-10-31	Sulfonamide derivatives for the treatment of diseases
GB0406388D0 (en)	2004-04-21	Sulfonamide derivatives for the treatment of diseases
IL177531A0 (en)	2006-12-10	Compounds for the treatment of diseases
GB0420867D0 (en)	2004-10-20	Compounds for the treatment of diseases
GB0425073D0 (en)	2004-12-15	Compounds for the treatment of diseases
GB0425064D0 (en)	2004-12-15	Compounds useful for the treatment of diseases
AP2006003743A0 (en)	2006-10-31	Compounds useful for the treatment of diseases