NO970373D0 - Benzoksazoler og pyridinderivater anvendelige ved behandling av type-II-diabetes - Google Patents
Benzoksazoler og pyridinderivater anvendelige ved behandling av type-II-diabetesInfo
- Publication number
- NO970373D0 NO970373D0 NO970373A NO970373A NO970373D0 NO 970373 D0 NO970373 D0 NO 970373D0 NO 970373 A NO970373 A NO 970373A NO 970373 A NO970373 A NO 970373A NO 970373 D0 NO970373 D0 NO 970373D0
- Authority
- NO
- Norway
- Prior art keywords
- benzoxazoles
- diabetes
- treatment
- type
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
| GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
| GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
| PCT/GB1995/001323 WO1996004261A1 (en) | 1994-07-29 | 1995-06-07 | Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes |
| PCT/EP1995/003038 WO1996004260A1 (en) | 1994-07-29 | 1995-07-28 | Benzoxazoles and pyridine derivatives useful in the treatment of the type ii diabetes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970373D0 true NO970373D0 (no) | 1997-01-28 |
| NO970373L NO970373L (no) | 1997-03-18 |
| NO307827B1 NO307827B1 (no) | 2000-06-05 |
Family
ID=27267309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO970373A NO307827B1 (no) | 1994-07-29 | 1997-01-28 | Benzoksazol- og pyridinderivater, anvendelse av dem og farmasøytisk preparat inneholdende dem |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0772605A1 (no) |
| AP (1) | AP776A (no) |
| BR (1) | BR9508468A (no) |
| CA (1) | CA2196079A1 (no) |
| CZ (1) | CZ25497A3 (no) |
| DZ (1) | DZ1916A1 (no) |
| FI (1) | FI970357A7 (no) |
| HU (1) | HUT76637A (no) |
| IL (3) | IL125525A (no) |
| MA (1) | MA23632A1 (no) |
| MX (1) | MX9700763A (no) |
| NO (1) | NO307827B1 (no) |
| OA (1) | OA10470A (no) |
| PL (1) | PL318766A1 (no) |
| SK (1) | SK12297A3 (no) |
| WO (2) | WO1996004261A1 (no) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
| ATE252074T1 (de) * | 1996-04-04 | 2003-11-15 | Sankyo Co | Phenylalkylcarbonsäure-derivate |
| US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
| US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
| BR9813019A (pt) | 1997-10-02 | 2000-09-05 | Sankyo Co | Derivados do ácido amidocarboxìlico, agentes para diminuir a glicose do sangue, redutor de lipìdio, para melhorar a resistência à insulina, anti-inflamatório, para imuno regulagem, para inibir a aldose reductase, para inibir a 5-lipoxigenase, para a geração de supressor de peróxido de lipìdio, para ativar a ppar, para minorar a osteoporose, e, composições para a terapia ou prevenção da diabete melito, da hiperlipemia, da obesidade, da tolerância à glicose prejudicada, da resistência à insulina que não a igt, do fìgado gorduroso, de complicações diabéticas, da arterioesclerose, da diabete melito gestacional, da sìndrome do ovário policìstico, da artroesteìte, da artrite reumática, de doenças alérgicas, da asma, do câncer, de doenças auto imunes, da pancreatite, e de cataratas |
| AU749505B2 (en) * | 1997-10-27 | 2002-06-27 | Dr. Reddy's Laboratories Limited | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
| US6265401B1 (en) * | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
| US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| AU752059B2 (en) | 1997-10-27 | 2002-09-05 | Dr. Reddy's Laboratories Limited | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
| US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| WO1999016758A1 (en) * | 1997-10-27 | 1999-04-08 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| WO1999019313A1 (en) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
| CN100357281C (zh) * | 1998-05-27 | 2007-12-26 | 雷迪实验室有限公司 | 双环化合物、其制备方法和包含它们的药物组合物 |
| CA2344309A1 (en) | 1998-09-17 | 2000-03-23 | Scott A. Biller | Method for treating diabetes employing an ap2 inhibitor and combination |
| US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
| WO2000023425A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6353018B1 (en) | 1998-10-21 | 2002-03-05 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
| EP1123297A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| WO2000023416A1 (en) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | New compounds, their preparation and use |
| EP1123269A1 (en) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| AU6325599A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
| US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
| US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
| JP2002528535A (ja) | 1998-10-29 | 2002-09-03 | ドクター・レディーズ・リサーチ・ファウンデーション | 新規抗糖尿病剤製造の改良方法 |
| WO2000063189A1 (en) * | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Crystalline r- guanidines, arginine or (l) -arginine (2s) -2- ethoxy -3-{4- [2-(10h -phenoxazin -10-yl)ethoxy]phenyl}propanoate |
| US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| EP1171431A1 (en) * | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Compounds, their preparation and use |
| US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
| US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
| PL351312A1 (en) * | 1999-04-20 | 2003-04-07 | Novo Nordisk As | New compounds, their preparation and use |
| WO2000063209A1 (en) * | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
| CZ20013832A3 (cs) * | 1999-04-28 | 2002-04-17 | Dr. Reddy's Research Foundation | Substituované bicyklické heterocyklické sloučeniny, způsob jejich přípravy a jejich pouľití jako antiobezitních a hypocholesterolemických činidel |
| DK1206457T3 (da) | 1999-08-27 | 2004-02-16 | Lilly Co Eli | Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER |
| CZ304346B6 (cs) * | 2000-01-19 | 2014-03-19 | Cadila Healthcare Ltd. | Substituovaný pyrrolový derivát s hypolipidemickou hypocholesteremickou aktivitou, způsob jeho přípravy a farmaceutický přípravek obsahující tyto sloučeniny |
| US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
| US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
| IL150259A0 (en) * | 2000-01-28 | 2002-12-01 | Novo Nordisk As | Alkylnyl-substituted propionic acid derivatives and their use against diabetes and obesity |
| US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
| WO2001087861A2 (en) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of treatment using benzoxazinones as peroxisome proliferator activated receptor gamma modulators |
| AU2001263083A1 (en) * | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4h-benzo(1,4)oxazin-3-ones |
| US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
| US6599899B2 (en) | 2000-05-12 | 2003-07-29 | Ortho-Mcneil Pharmaceutical, Inc. | Benzoxazinones as peroxisome proliferator activated receptor gamma modulators and method of treatment |
| US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
| US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
| US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
| WO2003059378A2 (en) | 2001-12-29 | 2003-07-24 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
| US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
| US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
| US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
| JPWO2008139879A1 (ja) * | 2007-04-26 | 2010-07-29 | ファルマフロンティア株式会社 | Ｇ蛋白質共役型レセプター抑制剤および医薬 |
| KR101733414B1 (ko) | 2011-01-31 | 2017-05-10 | 카딜라 핼쓰캐어 리미티드 | 지방이상증의 치료 |
| WO2014174524A1 (en) | 2013-04-22 | 2014-10-30 | Cadila Healthcare Limited | A novel composition for nonalcoholic fatty liver disease (nafld) |
| MX2015016403A (es) | 2013-05-30 | 2016-04-11 | Cadila Healthcare Ltd | Proceso para la preparacion de pirroles que tienen actividad hipolipidemica e hipocolesterolemica. |
| TW201636015A (zh) | 2013-07-05 | 2016-10-16 | 卡地拉保健有限公司 | 協同性組成物 |
| IN2013MU02470A (no) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
| WO2015033357A2 (en) | 2013-09-06 | 2015-03-12 | Cadila Healthcare Limited | An improved process for the preparation of pyrrole derivatives |
| WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
| MX382765B (es) | 2016-12-09 | 2025-03-13 | Zydus Lifesciences Ltd | Tratamiento para la colangitis biliar primaria. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| KR950702545A (ko) * | 1992-07-03 | 1995-07-29 | 데이빗 로버츠 | 약제로서의 헤테로시클릭 화합물(Heterocyclic compounds as pharmaceutical) |
-
1995
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/en not_active Ceased
- 1995-06-07 BR BR9508468A patent/BR9508468A/pt unknown
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/fr active
- 1995-07-27 MA MA23972A patent/MA23632A1/fr unknown
- 1995-07-27 IL IL12552595A patent/IL125525A/xx unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/xx unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 PL PL95318766A patent/PL318766A1/xx unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/hu unknown
- 1995-07-28 CA CA002196079A patent/CA2196079A1/en not_active Abandoned
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/cs unknown
- 1995-07-28 FI FI970357A patent/FI970357A7/fi unknown
- 1995-07-28 SK SK122-97A patent/SK12297A3/sk unknown
- 1995-07-28 MX MX9700763A patent/MX9700763A/es unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/en not_active Withdrawn
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/en not_active Ceased
-
1997
- 1997-01-28 NO NO970373A patent/NO307827B1/no not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL125525A0 (en) | 1999-03-12 |
| FI970357L (fi) | 1997-03-26 |
| HUT76637A (en) | 1997-10-28 |
| IL114759A (en) | 1999-10-28 |
| EP0772605A1 (en) | 1997-05-14 |
| WO1996004260A1 (en) | 1996-02-15 |
| AP776A (en) | 1999-10-28 |
| OA10470A (en) | 2002-04-08 |
| AP9700918A0 (en) | 1997-01-31 |
| PL318766A1 (en) | 1997-07-07 |
| DZ1916A1 (fr) | 2002-02-17 |
| NO970373L (no) | 1997-03-18 |
| SK12297A3 (en) | 1997-08-06 |
| CA2196079A1 (en) | 1996-02-15 |
| NO307827B1 (no) | 2000-06-05 |
| FI970357A7 (fi) | 1997-03-26 |
| MX9700763A (es) | 1997-05-31 |
| WO1996004261A1 (en) | 1996-02-15 |
| MA23632A1 (fr) | 1996-04-01 |
| BR9508468A (pt) | 1997-11-25 |
| IL114759A0 (en) | 1995-12-31 |
| FI970357A0 (fi) | 1997-01-28 |
| CZ25497A3 (en) | 1997-09-17 |
| IL125525A (en) | 2000-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JANUARY 2003 |