NO942720L - 1,5-benzobiazepinderivater og medisinsk anvendelse av disse - Google Patents

1,5-benzobiazepinderivater og medisinsk anvendelse av disse

Info

Publication number: NO942720L
Authority: NO; Norway
Prior art keywords: benzobiazepine; derivatives; medical use; medical; benzobiazepine derivatives
Prior art date: 1992-01-21

Application number

NO942720A

Other languages

English (en)

Other versions

NO942720D0 (no

NO305952B1 (no

Inventor

Harry Finch

David Gordon Trist

Giorgio Tarzia

Aldo Feriani

Original Assignee

Glaxo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-21

Filing date

1994-07-20

Publication date

1994-07-20

1994-07-20 Application filed by Glaxo Spa filed Critical Glaxo Spa

1994-07-20 Publication of NO942720L publication Critical patent/NO942720L/no

1994-07-20 Publication of NO942720D0 publication Critical patent/NO942720D0/no

1999-08-23 Publication of NO305952B1 publication Critical patent/NO305952B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO942720A 1992-01-21 1994-07-20 1,5-benzodiazepinderivater, anvendelse derav og farmasoeytiske preparater NO305952B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929201180A GB9201180D0 (en)	1992-01-21	1992-01-21	Chemical compounds
PCT/EP1993/000098 WO1993014074A1 (en)	1992-01-21	1993-01-19	1,5-benzodiazepine derivatives and their use in medicine

Publications (3)

Publication Number	Publication Date
NO942720L true NO942720L (no)	1994-07-20
NO942720D0 NO942720D0 (no)	1994-07-20
NO305952B1 NO305952B1 (no)	1999-08-23

Family

ID=10708914

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO942720A NO305952B1 (no)	1992-01-21	1994-07-20	1,5-benzodiazepinderivater, anvendelse derav og farmasoeytiske preparater

Country Status (29)

Country	Link
US (2)	US5580895A (no)
JP (1)	JP3253723B2 (no)
KR (1)	KR100263625B1 (no)
CN (1)	CN1049217C (no)
AP (1)	AP369A (no)
AU (2)	AU3450193A (no)
BG (1)	BG61876B1 (no)
CA (1)	CA2087672C (no)
CZ (1)	CZ283950B6 (no)
FI (1)	FI111632B (no)
GB (1)	GB9201180D0 (no)
GE (1)	GEP20001968B (no)
HU (2)	HU221297B1 (no)
IL (1)	IL104447A (no)
IS (1)	IS3970A (no)
MX (1)	MX9300261A (no)
MY (1)	MY131307A (no)
NO (1)	NO305952B1 (no)
NZ (1)	NZ245715A (no)
OA (1)	OA09964A (no)
PH (1)	PH30894A (no)
PL (1)	PL175340B1 (no)
RO (1)	RO114128B1 (no)
RU (1)	RU2124009C1 (no)
SK (1)	SK280173B6 (no)
TW (1)	TW226013B (no)
UA (1)	UA29416C2 (no)
WO (1)	WO1993014074A1 (no)
ZA (1)	ZA93375B (no)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9225492D0 (en) *	1992-12-05	1993-01-27	Glaxo Group Ltd	Amine derivatives
WO1994024151A1 (en) *	1993-04-15	1994-10-27	Glaxo Inc.	1,5 benzodiazepine derivatives having cck and/or gastrin antagonistic activity
GB9307833D0 (en) *	1993-04-15	1993-06-02	Glaxo Inc	Modulators of cholecystokinin and gastrin
GB9308431D0 (en) *	1993-04-23	1993-06-09	Glaxo Spa	Chemical compounds
GB9308421D0 (en) *	1993-04-23	1993-06-09	Glaxo Spa	Chemical compounds
GB2280182A (en) *	1993-07-20	1995-01-25	Glaxo Spa	Benzodiazepine derivatives
GB9314977D0 (en) *	1993-07-20	1993-09-01	Glaxo Spa	Chemical compounds
GB9314981D0 (en) *	1993-07-20	1993-09-01	Glaxo Spa	Chemical compounds
GB9315018D0 (en) *	1993-07-20	1993-09-01	Glaxo Spa	Chemical compounds
US5739129A (en) *	1994-04-14	1998-04-14	Glaxo Wellcome Inc.	CCK or gastrin modulating 5-heterocyclic-1, 5 benzodiazepines
JPH09511223A (ja) *	1994-04-14	1997-11-11	グラクソ、ウェルカム、インコーポレーテッド	Ｃｃｋまたはガストリンを調節する５−ヘテロシクロ−１，５−ベンゾジアゼピン
PE27497A1 (es) *	1994-04-15	1997-08-07	Glaxo Inc	Derivados de 1,5 benzodiazepina
GB9420748D0 (en) *	1994-10-14	1994-11-30	Glaxo Inc	1,5 benzodiazepine derivatives
US5780464A (en) *	1994-10-14	1998-07-14	Glaxo Wellcome Inc.	Enteric coated compositions of 1,5-benzodiazepine derivatives having CCK antagonistic or agonistic activity
CA2239293A1 (en)	1995-12-11	1997-06-19	New England Medical Center Hosptials, Inc.	Assay for and uses of peptide hormone receptor ligands
US5750353A (en) *	1995-12-11	1998-05-12	New England Medical Center Hospitals, Inc.	Assay for non-peptide agonists to peptide hormone receptors
DE69724644T4 (de) *	1996-12-10	2006-08-10	Zeria Pharmaceutical Co., Ltd.	1,5-benzodiazepin-derivate
RU2321583C2 (ru) *	2001-01-22	2008-04-10	Мемори Фармасьютиклз Корпорейшн	Применение производных анилина в качестве ингибиторов фосфодиэстеразы 4
JP4613157B2 (ja) *	2003-01-14	2011-01-12	サイトキネティクス・インコーポレーテッド	化合物、組成物および方法
GB0307918D0 (en) *	2003-04-05	2003-05-14	Astrazeneca Ab	Therapeutic use
RU2377987C2 (ru) *	2003-11-18	2010-01-10	Бёрингер Ингельхайм Интернациональ Гмбх	Твердая лекарственная форма
PL216049B1 (pl)	2004-06-17	2014-02-28	Cytokinetics Inc	Pochodne mocznika, kompozycje zawierajace pochodne mocznika oraz zastosowanie pochodnych mocznika do wytwarzania leku do leczenia niewydolnosci serca
US7538223B2 (en)	2005-08-04	2009-05-26	Cytokinetics, Inc.	Compounds, compositions and methods
US7825120B2 (en)	2005-12-15	2010-11-02	Cytokinetics, Inc.	Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas
US20070161617A1 (en)	2005-12-15	2007-07-12	Morgan Bradley P	Certain chemical entities, compositions and methods
WO2007078815A2 (en)	2005-12-16	2007-07-12	Cytokinetics, Inc.	Certain chemical entities, compositions, and methods
JP5178526B2 (ja)	2005-12-19	2013-04-10	サイトキネティクス・インコーポレーテッド	化合物、組成物および方法
CU20090172A6 (es)	2009-10-09	2011-10-05	Facultad De Quimica Universidad De La Habana	Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular
JP6014904B2 (ja)	2011-07-29	2016-10-26	国立大学法人徳島大学	Ｅｒａｐ１由来ペプチド及びその使用
CN103435562B (zh) *	2013-08-26	2016-02-24	华东理工大学	6-取代苯并二氮卓-2,4-二酮类化合物及其用途
CN108200760B (zh)	2015-07-22	2022-04-01	英安塔制药有限公司	作为rsv抑制剂的苯并二氮杂䓬衍生物
EP3402799B1 (en)	2016-01-15	2022-05-04	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as rsv inhibitors
ES2923521T3 (es)	2017-02-16	2022-09-28	Enanta Pharm Inc	Procesos para la preparación de derivados de benzodiazepina
WO2018226801A1 (en) *	2017-06-07	2018-12-13	Enanta Pharmaceuticals, Inc.	Aryldiazepine derivatives as rsv inhibitors
US11091501B2 (en)	2017-06-30	2021-08-17	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as RSV inhibitors
WO2019006291A1 (en)	2017-06-30	2019-01-03	Enanta Pharmaceuticals, Inc.	HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
JP7198811B2 (ja)	2017-09-29	2023-01-04	エナンタファーマシューティカルズインコーポレイテッド	Ｒｓｖ阻害剤としての組み合わせ医薬剤
WO2019094920A1 (en)	2017-11-13	2019-05-16	Enanta Pharmaceuticals, Inc.	Azepin-2-one derivatives as rsv inhibitors
WO2019199908A1 (en)	2018-04-11	2019-10-17	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as rsv inhibitors
US20220098256A1 (en)	2018-11-30	2022-03-31	Tokushima University	Therapeutic agent for breast cancer comprising big3-phb2 interaction-inhibiting peptide derived from phb2
CN113710276B (zh)	2019-03-18	2024-03-29	英安塔制药有限公司	苯二氮䓬衍生物作为rsv抑制剂
US11179400B2 (en)	2019-04-09	2021-11-23	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as RSV inhibitors
US11505558B1 (en)	2019-10-04	2022-11-22	Enanta Pharmaceuticals, Inc.	Antiviral heterocyclic compounds
UY39032A (es)	2020-01-24	2021-07-30	Enanta Pharm Inc	Compuestos heterocíclicos como agentes antivirales
WO2022010882A1 (en)	2020-07-07	2022-01-13	Enanta Pharmaceuticals, Inc,	Dihydroquinoxaline and dihydropyridopyrazine derivatives as rsv inhibitors
US11945824B2 (en)	2020-10-19	2024-04-02	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as anti-viral agents
AR129003A1 (es)	2022-04-07	2024-07-03	Enanta Pharm Inc	Compuestos heterocíclicos antivirales
US12162857B2 (en)	2022-04-27	2024-12-10	Enanta Pharmaceuticals, Inc.	Antiviral compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3984398A (en) *	1966-12-14	1976-10-05	Roussel-Uclaf	1,5-Benzodiazepine-2,4-diones
US4207228A (en) *	1977-09-21	1980-06-10	The B. F. Goodrich Company	UV-Light-stabilized compositions containing substituted 1,5-diazacycloalkanes, novel compounds and synthesis thereof
JPS60158190A (ja) *	1984-01-30	1985-08-19	Eisai Co Ltd	ヒダントイン誘導体およびその製法ならびにそれを含有する医薬
US4647561A (en) *	1985-08-05	1987-03-03	E. R. Squibb & Sons, Inc.	1,5-benzodiazepine compounds
FR2641280B1 (fr) *	1988-12-29	1994-01-21	Roussel Uclaf	Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments

1992
- 1992-01-21 GB GB929201180A patent/GB9201180D0/en active Pending
- 1992-01-21 GE GEAP19922651A patent/GEP20001968B/en unknown
1993
- 1993-01-15 US US08/256,359 patent/US5580895A/en not_active Expired - Fee Related
- 1993-01-19 RO RO94-01216A patent/RO114128B1/ro unknown
- 1993-01-19 KR KR1019940702491A patent/KR100263625B1/ko not_active Expired - Fee Related
- 1993-01-19 RU RU94037768A patent/RU2124009C1/ru active
- 1993-01-19 PL PL93304684A patent/PL175340B1/pl unknown
- 1993-01-19 SK SK864-94A patent/SK280173B6/sk unknown
- 1993-01-19 HU HU9402150A patent/HU221297B1/hu not_active IP Right Cessation
- 1993-01-19 UA UA94005364A patent/UA29416C2/uk unknown
- 1993-01-19 WO PCT/EP1993/000098 patent/WO1993014074A1/en not_active Ceased
- 1993-01-19 AU AU34501/93A patent/AU3450193A/en not_active Abandoned
- 1993-01-19 CZ CZ941736A patent/CZ283950B6/cs not_active IP Right Cessation
- 1993-01-20 NZ NZ245715A patent/NZ245715A/en unknown
- 1993-01-20 CA CA002087672A patent/CA2087672C/en not_active Expired - Fee Related
- 1993-01-20 AP APAP/P/1993/000478A patent/AP369A/en active
- 1993-01-20 PH PH45583A patent/PH30894A/en unknown
- 1993-01-20 IS IS3970A patent/IS3970A/is unknown
- 1993-01-20 IL IL104447A patent/IL104447A/en not_active IP Right Cessation
- 1993-01-20 JP JP02483193A patent/JP3253723B2/ja not_active Expired - Fee Related
- 1993-01-20 AU AU31935/93A patent/AU661749B2/en not_active Ceased
- 1993-01-20 MY MYPI93000093A patent/MY131307A/en unknown
- 1993-01-20 MX MX9300261A patent/MX9300261A/es not_active IP Right Cessation
- 1993-01-20 ZA ZA93375A patent/ZA93375B/xx unknown
- 1993-01-21 CN CN93101143A patent/CN1049217C/zh not_active Expired - Fee Related
- 1993-02-02 TW TW082100666A patent/TW226013B/zh active
1994
- 1994-06-27 BG BG98881A patent/BG61876B1/bg unknown
- 1994-07-18 OA OA60539A patent/OA09964A/en unknown
- 1994-07-19 FI FI943421A patent/FI111632B/fi active
- 1994-07-20 NO NO942720A patent/NO305952B1/no unknown
1995
- 1995-06-16 HU HU95P/P00242P patent/HU211295A9/hu unknown
1996
- 1996-07-01 US US08/674,259 patent/US5637697A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
BG61876B1 (bg)	1998-08-31
OA09964A (en)	1995-12-11
WO1993014074A1 (en)	1993-07-22
CA2087672C (en)	2003-08-05
MY131307A (en)	2007-08-30
RO114128B1 (ro)	1999-01-29
HU9402150D0 (en)	1994-09-28
GEP20001968B (en)	2000-03-05
IS3970A (is)	1993-07-22
CN1049217C (zh)	2000-02-09
FI111632B (fi)	2003-08-29
IL104447A0 (en)	1993-05-13
US5637697A (en)	1997-06-10
MX9300261A (es)	1994-03-31
AU3193593A (en)	1993-07-22
AP9300478A0 (en)	1993-01-31
BG98881A (bg)	1995-03-31
HUT67375A (en)	1995-03-28
AU661749B2 (en)	1995-08-03
SK280173B6 (sk)	1999-09-10
HU221297B1 (en)	2002-09-28
RU94037768A (ru)	1996-08-10
IL104447A (en)	1998-02-22
HU211295A9 (en)	1995-11-28
ZA93375B (en)	1994-07-18
NZ245715A (en)	1995-07-26
PL175340B1 (pl)	1998-12-31
AP369A (en)	1994-11-06
PH30894A (en)	1997-12-23
TW226013B (no)	1994-07-01
SK86494A3 (en)	1995-03-08
JPH07118244A (ja)	1995-05-09
CZ173694A3 (en)	1995-09-13
JP3253723B2 (ja)	2002-02-04
CZ283950B6 (cs)	1998-07-15
NO942720D0 (no)	1994-07-20
RU2124009C1 (ru)	1998-12-27
KR100263625B1 (ko)	2000-11-01
FI943421L (fi)	1994-07-19
CN1074678A (zh)	1993-07-28
FI943421A0 (fi)	1994-07-19
GB9201180D0 (en)	1992-03-11
CA2087672A1 (en)	1993-07-22
NO305952B1 (no)	1999-08-23
UA29416C2 (uk)	2000-11-15
US5580895A (en)	1996-12-03
AU3450193A (en)	1993-08-03

Publication	Publication Date	Title
NO942720D0 (no)	1994-07-20	1,5-benzobiazepinderivater og medisinsk anvendelse av disse
FI961939A7 (fi)	1996-05-07	Antitromboottiset amidinofenyylialaniini- ja amidinopyridyylialaniinijohdannaiset
NO961425D0 (no)	1996-04-11	1N-alkyl-N-arylpyrimidinaminer og derivater derav
NO953991D0 (no)	1995-10-06	Ultrasomisk og elektro-kirurgisk håndstykke av piezotype
IS3720A7 (is)	1991-12-21	Afleiður dialkoxy-pyridinyl-benzimidazole, aðferðvið lögun þeirra og lyfjafræðileg notkun
DE59208263D1 (de)	1997-04-30	3-Aryl-4-hydroxy-delta3-dihydrofuranon- und 3-Aryl-4-hydroxy-delta3-dihydrothiophenon-Derivate
NO943511L (no)	1995-03-23	Farmasöytiske preparater og anvendelse derav
DE69415163D1 (de)	1999-01-21	ZUZAMMENSETUNG ENTHALTEND 1,1,1,2,3,4,4,5,5,5,-DECAFLUORPENTAN UND n-PROPANOL
IS4481A (is)	1997-05-12	Díhýdrópyramídín og notkun þeirra
FI961599A7 (fi)	1996-06-07	1N-alkyyli-N-aryylipyrimidiiniamiineja ja niiden johdannaisia
FI952179A7 (fi)	1995-05-05	Uusia 3,3-difenyylipropyyliamiineja, niiden käyttö ja valmistus
NO975439D0 (no)	1997-11-26	Ketonderivater og medisinsk anvendelse derav
FI934004A7 (fi)	1994-03-16	7-isoindolinyylikinoloni- ja naftyridonijohdannaiset
EP0482649A3 (en)	1992-11-19	Cm-chitin derivatives and use thereof
FI931234A0 (fi)	1993-03-19	Foerfarande foer oevervakning av en patients tillstaond
NO922934D0 (no)	1992-07-23	Cykloheksan- og tetrahydropyranderivater
FI923458A7 (fi)	1992-07-31	4,5-sykloalkano-3-bentsatsepin-7-olijohdannaiset ja niiden käyttö
IS4140A (is)	1994-09-21	Notkun á ferróseni og/eða ferrósenafleiðum
NO921086L (no)	1992-10-06	Fremgangsmaate for fremstilling og anvendelse av substituerte 2',3'-didesoksy-5-trifluormetyluridiner
NO303392B1 (no)	1998-07-06	Polyetere, samt fremstilling og anvendelse av disse
ZA913171B (en)	1992-02-26	1,5-benzothiazepinone derivatives,their preparations and pharmaceutical use
NO985572D0 (no)	1998-11-27	Substituerte amidinobenzenderivater og medisinske preparater derav
DE69226430D1 (de)	1998-09-03	Fungizide 4-thioxooxazolidin-2-one und 4-iminooxazolidin-2-one
NO905221D0 (no)	1990-12-03	Steriliseringsblandinger og anvendelse derav.
NO179907C (no)	1997-01-08	Benzokinoksaliner og farmasöytiske preparater inneholdende de samme