NO903832L - Aminosyrederivater. - Google Patents

Aminosyrederivater.

Info

Publication number: NO903832L
Authority: NO; Norway
Prior art keywords: amino acid; acid derivative; derivative; amino; acid
Prior art date: 1989-09-04

Application number

NO90903832A

Other languages

English (en)

Other versions

NO903832D0 (no

Inventor

Quirico Branca

Werner Neidhart

Henri Ramuz

Heinz Stadler

Wolfgang Wostl

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-04

Filing date

1990-09-03

Publication date

1991-03-05

1990-09-03 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1990-09-03 Publication of NO903832D0 publication Critical patent/NO903832D0/no

1991-03-05 Publication of NO903832L publication Critical patent/NO903832L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/25—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrrole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Thiazole And Isothizaole Compounds (AREA)

NO90903832A 1989-09-04 1990-09-03 Aminosyrederivater. NO903832L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH319289		1989-09-04
CH233690		1990-07-12

Publications (2)

Publication Number	Publication Date
NO903832D0 NO903832D0 (no)	1990-09-03
NO903832L true NO903832L (no)	1991-03-05

Family

ID=25690187

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO90903832A NO903832L (no)	1989-09-04	1990-09-03	Aminosyrederivater.

Country Status (14)

Country	Link
US (1)	US5688946A (no)
EP (1)	EP0416373A3 (no)
JP (1)	JPH0399047A (no)
KR (1)	KR910006224A (no)
AU (1)	AU646640B2 (no)
CA (1)	CA2023099A1 (no)
FI (1)	FI904360A7 (no)
HU (1)	HUT58060A (no)
IE (1)	IE903197A1 (no)
IL (1)	IL95503A0 (no)
MC (1)	MC2151A1 (no)
NO (1)	NO903832L (no)
NZ (1)	NZ235057A (no)
PT (1)	PT95192A (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE68045B1 (en) *	1990-05-11	1996-05-15	Abbott Lab	Renin inhibitors
US5275950A (en) *	1990-05-11	1994-01-04	Abbott Laboratories	Process for the preparation of a renin inhibiting compound
US5278161A (en) *	1990-06-28	1994-01-11	Hoffmann-La Roche Inc.	Amino acid derivatives useful as renin inhibitors
DE4040056A1 (de) *	1990-12-14	1992-06-17	Merck Patent Gmbh	Saeureamide
TW198712B (no) *	1991-04-17	1993-01-21	Hoffmann La Roche
US5268361A (en) *	1991-06-07	1993-12-07	Sri International	Hydroxyazido derivatives and related compounds as renin inhibitors
CA2095671A1 (en) *	1992-06-04	1993-12-05	Quirico Branca	Amino acid derivatives
US5559256A (en) *	1992-07-20	1996-09-24	E. R. Squibb & Sons, Inc.	Aminediol protease inhibitors
US5317039A (en) *	1992-07-20	1994-05-31	G. D. Searle & Co.	Cyclopropyl-alanine aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
US5268391A (en) *	1992-07-20	1993-12-07	C. D. Searle & Co.	Propargyl-terminated cycloalkylalkyl-P2-site substituted aryl/alkylsulfonyl-terminated alanine amino-diol compounds for treatment of hypertension
US5246969A (en) *	1992-07-20	1993-09-21	G. D. Searle & Co.	Di-propargyl-containing aryl/alkylsulfonyl-terminated alanine amino-diol compounds for treatment of hypertension
US5314920A (en) *	1992-07-20	1994-05-24	G. D. Searle & Co.	Ethynyl-alanine aryl/alkylsulfonyl-terminated amino-diol compounds for treatment of hypertension
US5212185A (en) *	1992-08-14	1993-05-18	G. D. Searle & Co.	Piperidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
US5312838A (en) *	1992-09-21	1994-05-17	G. D. Searle & Co.	β-alanineamide aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
ES2100109B1 (es) *	1993-07-14	1998-02-16	Squibb & Sons Inc	Inhibidores de proteasas de aminodiol.
US5414018A (en) *	1993-09-24	1995-05-09	G. D. Searle & Co.	Alkylaminoalkyl-terminated sulfide/sulfonyl-containing propargyl amino-diol compounds for treatment of hypertension
US5416119A (en) *	1993-10-25	1995-05-16	G. D. Searle & Co.	Alkylaminoalkyl-terminated sulfide/sulfonyl-containing cycloalkyl-alanine amino-diol compounds for treatment of hypertension
US5432201A (en) *	1993-11-22	1995-07-11	G. D. Searle & Co.	Alkylaminoalkyl-sulfonyl-terminated β-alanineamide amino-diol compounds for treatment of hypertension
IL140499A0 (en)	1998-07-06	2002-02-10	Guilford Pharm Inc	Nalladase inhibitors useful as pharmaceutical compounds and compositions
JP2002538151A (ja) *	1999-03-02	2002-11-12	ベーリンガーインゲルハイムファーマシューティカルズインコーポレイテッド	カテプシンの可逆的インヒビターとして有用な化合物
JP2002201168A (ja) *	2000-12-28	2002-07-16	Kaken Pharmaceut Co Ltd	シクロヘキサン誘導体
WO2002062850A2 (en) *	2001-02-02	2002-08-15	Millennium Pharmaceuticals, Inc.	Hybrid antibodies and uses thereof
US7186855B2 (en)	2001-06-11	2007-03-06	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en)	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en)	2001-06-11	2004-11-16	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
UA108742C2 (uk)	2009-09-23	2015-06-10		Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
WO2015049239A1 (en) *	2013-10-04	2015-04-09	Solvay Specialty Polymers Italy S.P.A.	Process for the synthesis of fluoralkyl sulfonate salts
KR20190068537A (ko) *	2016-09-18	2019-06-18	에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨	Yap1과 oct4의 상호작용을 표적으로 하는 yap1 저해제
GB202217507D0 (en) *	2022-11-23	2023-01-04	Imperial College Innovations Ltd	Natural killer cells

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4652551A (en) *	1984-06-22	1987-03-24	Abbott Laboratories	Renin inhibiting compounds
US4845079A (en) *	1985-01-23	1989-07-04	Luly Jay R	Peptidylaminodiols
WO1987004349A1 (en) *	1986-01-16	1987-07-30	Joseph Dellaria	Peptide analogs
NZ218937A (en) *	1986-01-16	1990-03-27	Abbott Lab	Functionalised peptidyl aminodiols and -triols as renin inhibitors and pharmaceutical compositions
US4726941A (en) *	1986-01-23	1988-02-23	Regents Of The University Of Minnesota	Acylated cyanamide composition for treating ethanol ingestion
US5032577A (en) *	1986-12-31	1991-07-16	Abbott Laboratories	Peptidylaminodiols
DE3856166T2 (de) *	1987-09-29	1998-08-06	Banyu Pharma Co Ltd	N-Acylaminosäurederivate und deren Verwendung
EP0313847A3 (en) *	1987-10-01	1989-11-29	G.D. Searle & Co.	Non-peptidyl alpha-succinamidoacyl aminodiols as anti-hypertensive agents
CA1328333C (en) *	1988-03-04	1994-04-05	Quirico Branca	Amino acid derivatives
TW225540B (no) *	1990-06-28	1994-06-21	Shionogi & Co
ZA917693B (en) *	1990-09-27	1992-05-27	Merck & Co Inc	Fibrinogen receptor antagonists

1990
- 1990-08-10 CA CA002023099A patent/CA2023099A1/en not_active Abandoned
- 1990-08-22 EP EP19900116088 patent/EP0416373A3/de not_active Withdrawn
- 1990-08-27 AU AU61360/90A patent/AU646640B2/en not_active Ceased
- 1990-08-27 NZ NZ235057A patent/NZ235057A/en unknown
- 1990-08-28 IL IL95503A patent/IL95503A0/xx unknown
- 1990-08-29 HU HU905676A patent/HUT58060A/hu unknown
- 1990-08-30 MC MC902146A patent/MC2151A1/fr unknown
- 1990-08-31 JP JP2228473A patent/JPH0399047A/ja active Pending
- 1990-09-03 NO NO90903832A patent/NO903832L/no unknown
- 1990-09-03 IE IE319790A patent/IE903197A1/en unknown
- 1990-09-03 PT PT95192A patent/PT95192A/pt not_active Application Discontinuation
- 1990-09-04 FI FI904360A patent/FI904360A7/fi not_active IP Right Cessation
- 1990-09-04 KR KR1019900013893A patent/KR910006224A/ko not_active Withdrawn
1994
- 1994-07-19 US US08/277,111 patent/US5688946A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5688946A (en)	1997-11-18
JPH0399047A (ja)	1991-04-24
AU646640B2 (en)	1994-03-03
FI904360A0 (fi)	1990-09-04
IE903197A1 (en)	1991-03-13
HU905676D0 (en)	1991-03-28
AU6136090A (en)	1991-03-07
NZ235057A (en)	1994-12-22
MC2151A1 (fr)	1992-03-10
KR910006224A (ko)	1991-04-27
CA2023099A1 (en)	1991-03-05
IL95503A0 (en)	1991-06-30
EP0416373A2 (de)	1991-03-13
PT95192A (pt)	1991-05-22
NO903832D0 (no)	1990-09-03
FI904360A7 (fi)	1991-03-05
EP0416373A3 (en)	1992-05-27
HUT58060A (en)	1992-01-28

Publication	Publication Date	Title
NO901399L (no)	1990-10-01	Aminosyrederivater.
FI905983L (fi)	1991-06-12	Aminosyraderivat.
NO892407L (no)	1989-12-14	Aminosyrederivater.
NO903832D0 (no)	1990-09-03	Aminosyrederivater.
NO901033D0 (no)	1990-03-05	Aminosyrederivater.
DE59008394D1 (de)	1995-03-16	Aminosäureamid-Derivate.
FI891006A7 (fi)	1989-09-05	Aminosyraderivat.
FI920420A7 (fi)	1992-08-02	Aminosyraderivat.
FI913236L (fi)	1992-01-05	9-purinylfosfonsyraderivat.
DE122005000012I1 (de)	2005-06-23	N-(Pyrrolo(2-3-d)pyrimidin-3-ylacyl)-Glutamins{urederivate.
NO884434D0 (no)	1988-10-05	Aminosyrederivater.
DE3787657D1 (de)	1993-11-11	Aminosäure-Derivate.
NO901533D0 (no)	1990-04-04	Aminosyrederivater.
FI892362L (fi)	1989-12-02	Buten- eller propensyraderivat.
FI900024A7 (fi)	1990-07-06	Pyrrolylfenyl-substituerade hydroxamsyraderivat.
NO912537D0 (no)	1991-06-27	Aminosyrederivater.
NO890635D0 (no)	1989-02-15	Reninhemmende aminosyrederivater.
FI891761L (fi)	1989-10-15	Aminosyraderivat.
FI906104L (fi)	1991-06-14	Naftylsulfonylalkansyraderivat.
DE69018816D1 (de)	1995-05-24	Aminosäurederivate.
NO901519D0 (no)	1990-04-03	Aminosyrederivater.
DE59002430D1 (de)	1993-09-30	Cyclopropanoylaminosäureamid-Derivate.
FI925068L (fi)	1993-05-20	Aminosyraderivat
ATE105549T1 (de)	1994-05-15	Aminosaeure-derivate.
ATE95518T1 (de)	1993-10-15	Aminosaeure-derivate.