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FI900024A7 - Pyrrolylfenyl-substituerade hydroxamsyraderivat. - Google Patents

Pyrrolylfenyl-substituerade hydroxamsyraderivat. Download PDF

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Publication number
FI900024A7
FI900024A7 FI900024A FI900024A FI900024A7 FI 900024 A7 FI900024 A7 FI 900024A7 FI 900024 A FI900024 A FI 900024A FI 900024 A FI900024 A FI 900024A FI 900024 A7 FI900024 A7 FI 900024A7
Authority
FI
Finland
Prior art keywords
pyrrolilphenyl
substituerade
acid derivatives
hydroxam
hydroxam acid
Prior art date
Application number
FI900024A
Other languages
English (en)
Other versions
FI900024A0 (fi
Inventor
Jan W F Wasley
Karl Olaf Gelotte
Harold Meckler
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI900024A0 publication Critical patent/FI900024A0/fi
Publication of FI900024A7 publication Critical patent/FI900024A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FI900024A 1989-01-05 1990-01-03 Pyrrolylfenyl-substituerade hydroxamsyraderivat. FI900024A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29390889A 1989-01-05 1989-01-05

Publications (2)

Publication Number Publication Date
FI900024A0 FI900024A0 (fi) 1990-01-03
FI900024A7 true FI900024A7 (fi) 1990-07-06

Family

ID=23131076

Family Applications (1)

Application Number Title Priority Date Filing Date
FI900024A FI900024A7 (fi) 1989-01-05 1990-01-03 Pyrrolylfenyl-substituerade hydroxamsyraderivat.

Country Status (12)

Country Link
EP (1) EP0378991A1 (fi)
JP (1) JPH02270861A (fi)
KR (1) KR900011724A (fi)
AU (1) AU4765090A (fi)
CA (1) CA2007085A1 (fi)
DD (1) DD291551A5 (fi)
FI (1) FI900024A7 (fi)
HU (1) HUT53608A (fi)
IL (1) IL92915A0 (fi)
NO (1) NO900025L (fi)
PT (1) PT92762A (fi)
ZA (1) ZA9050B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5140047A (en) * 1991-05-03 1992-08-18 Smithkline Beecham Corporation Lipoxygenase inhibitors
ES2104424T3 (es) * 1993-11-26 1997-10-01 Pfizer Compuestos de isoxazolina como agentes antiinflamatorios.
WO1995024192A1 (en) * 1994-03-09 1995-09-14 Pfizer Inc. Isoxazoline compounds as 5-lipoxygenase inhibitors
AU726204B2 (en) * 1997-02-27 2000-11-02 Wyeth Holdings Corporation N-hydroxy-2-(alkyl, aryl or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
US6172057B1 (en) 1997-02-27 2001-01-09 American Cyanamid Company N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
EP1284260A4 (en) * 2000-05-22 2004-03-31 Takeda Chemical Industries Ltd TYROSIN PHOSPHATASE INHIBITORS
AU2001280167A1 (en) * 2000-08-31 2002-03-13 Wakunaga Pharmaceutical Co.,Ltd Novel propenohydroxamic acid derivatives
US7169801B2 (en) 2003-03-17 2007-01-30 Takeda San Diego, Inc. Histone deacetylase inhibitors
US20050159470A1 (en) * 2003-12-19 2005-07-21 Syrrx, Inc. Histone deacetylase inhibitors
CN101360723A (zh) 2005-09-16 2009-02-04 武田药品工业株式会社 制备嘧啶二酮衍生物的方法
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0082109A3 (de) * 1981-10-28 1985-04-17 Ciba-Geigy Ag Substituierte 2-Hydroxy-phenylessigsäuren und Derivate davon
FR2551063A1 (fr) * 1983-08-22 1985-03-01 Inst Nat Sante Rech Med Nouveaux dimethyl-2,5 pyrroles, leur procede de preparation et leur application en therapeutique
DE3686733T2 (de) * 1985-03-16 1993-02-11 Wellcome Found Aryl-derivate.
US4792560A (en) * 1985-04-03 1988-12-20 Rorer Pharmaceutical Corporation Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways
GB8531838D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives

Also Published As

Publication number Publication date
PT92762A (pt) 1990-07-31
EP0378991A1 (en) 1990-07-25
KR900011724A (ko) 1990-08-02
CA2007085A1 (en) 1990-07-05
HU900040D0 (en) 1990-03-28
AU4765090A (en) 1990-07-12
ZA9050B (en) 1990-08-29
IL92915A0 (en) 1990-09-17
DD291551A5 (de) 1991-07-04
FI900024A0 (fi) 1990-01-03
HUT53608A (en) 1990-11-28
NO900025L (no) 1990-07-06
JPH02270861A (ja) 1990-11-05
NO900025D0 (no) 1990-01-04

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: CIBA-GEIGY AG