NO308301B1 - FremgangsmÕte for fremstilling av enantiomer-rene cykloalkanoindol- og azaindol- og pyrimido[1,2a]- indolkarboksylsyrer og deres aktiverte derivater, mellomprodukter samt anvendelse av disse - Google Patents

FremgangsmÕte for fremstilling av enantiomer-rene cykloalkanoindol- og azaindol- og pyrimido[1,2a]- indolkarboksylsyrer og deres aktiverte derivater, mellomprodukter samt anvendelse av disse

Info

Publication number: NO308301B1
Authority: NO; Norway
Prior art keywords: cycloalkanoindole; azaindole; pyrimido; intermediates; preparation
Prior art date: 1996-04-04

Application number

NO971513A

Other languages

English (en)

Norwegian (no)

Other versions

NO971513L (no

NO971513D0 (no

Inventor

Jan-Bernd Lenfers

Peter Fey

Paul Naab

Kai Van Laak

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-04

Filing date

1997-04-03

Publication date

2000-08-28

1997-04-03 Application filed by Bayer Ag filed Critical Bayer Ag

1997-04-03 Publication of NO971513D0 publication Critical patent/NO971513D0/no

1997-10-06 Publication of NO971513L publication Critical patent/NO971513L/no

2000-08-28 Publication of NO308301B1 publication Critical patent/NO308301B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/65—Halogen-containing esters of unsaturated acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO971513A 1996-04-04 1997-04-03 FremgangsmÕte for fremstilling av enantiomer-rene cykloalkanoindol- og azaindol- og pyrimido[1,2a]- indolkarboksylsyrer og deres aktiverte derivater, mellomprodukter samt anvendelse av disse NO308301B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19613549A DE19613549A1 (de)	1996-04-04	1996-04-04	Verfahren zur Herstellung von enantiomerenreinen Cycloalkano-indol- und azaindol-carbonsäuren und deren aktivierte Derivate

Publications (3)

Publication Number	Publication Date
NO971513D0 NO971513D0 (no)	1997-04-03
NO971513L NO971513L (no)	1997-10-06
NO308301B1 true NO308301B1 (no)	2000-08-28

Family

ID=7790501

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO971513A NO308301B1 (no)	1996-04-04	1997-04-03	FremgangsmÕte for fremstilling av enantiomer-rene cykloalkanoindol- og azaindol- og pyrimido[1,2a]- indolkarboksylsyrer og deres aktiverte derivater, mellomprodukter samt anvendelse av disse
NO20003784A NO20003784D0 (no)	1996-04-04	2000-07-24	FremgangsmÕte for fremstilling av enansiomert rene cykloalkanoindolkarboksylsyre og azaindolkarboksylsyrer og pyrimido 1,2a indolkarboksylsyrer og derivater derav

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20003784A NO20003784D0 (no)	1996-04-04	2000-07-24	FremgangsmÕte for fremstilling av enansiomert rene cykloalkanoindolkarboksylsyre og azaindolkarboksylsyrer og pyrimido 1,2a indolkarboksylsyrer og derivater derav

Country Status (27)

Country	Link
US (1)	US5952498A (es)
EP (1)	EP0799829B1 (es)
JP (2)	JP4235268B2 (es)
KR (1)	KR970069988A (es)
CN (2)	CN1067394C (es)
AR (2)	AR006544A1 (es)
AT (1)	ATE246193T1 (es)
AU (1)	AU722592B2 (es)
BR (1)	BR9701672A (es)
CA (1)	CA2201435C (es)
CZ (1)	CZ102197A3 (es)
DE (2)	DE19613549A1 (es)
DZ (1)	DZ2202A1 (es)
EE (1)	EE9700079A (es)
ES (1)	ES2202506T3 (es)
HR (1)	HRP970178A2 (es)
HU (1)	HU218494B (es)
ID (1)	ID16794A (es)
IL (1)	IL120591A (es)
MA (1)	MA24130A1 (es)
NO (2)	NO308301B1 (es)
NZ (1)	NZ314498A (es)
PL (1)	PL319269A1 (es)
SG (1)	SG60050A1 (es)
SK (1)	SK42897A3 (es)
TN (1)	TNSN97060A1 (es)
ZA (1)	ZA972831B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4435477A1 (de) *	1994-10-04	1996-04-11	Bayer Ag	Cycloalkano-indol- und -azaindol-derivate
AU2001244635A1 (en) *	2000-03-30	2001-10-15	Yamanouchi Pharmaceutical Co..Ltd.	Hydrazide derivatives
WO2005051382A1 (ja) *	2003-11-28	2005-06-09	Astellas Pharma Inc.	脂質低下作用増強剤
NZ549721A (en)	2004-03-05	2010-08-27	Univ Pennsylvania	Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side-effects
AU2005230397B2 (en) *	2004-04-09	2010-04-08	Elanco Animal Health Ireland Limited	Intermittent dosing regimen for the treatment of overweight with MTP-inhibitors
JP2009511634A (ja) *	2005-10-18	2009-03-19	エージェリオンファーマシューティカルズ	哺乳動物において高脂血症に関連する障害を治療する方法
US20080051427A1 (en) *	2006-05-18	2008-02-28	Fritz Schuckler	Pharmaceutical Compositions and Methods of Using Same
JP2010513534A (ja) *	2006-12-21	2010-04-30	エージェリオンファーマシューティカルズ，インコーポレイテッド	Ｍｔｐインヒビターおよびコレステロール吸収インヒビターを含む組み合わせを用いて肥満症を処置する方法
WO2008124384A2 (en) *	2007-04-03	2008-10-16	Aegerion Pharmaceuticals, Inc.	Combinations of mtp inhibitors with cholesterol absorption inhibitors or interferon for treating hepatitis c
CA2899247C (en)	2013-03-14	2023-04-04	Osteoqc Inc.	Alkyl-amine harmine derivatives for promoting bone growth
AU2019321434B2 (en)	2018-08-14	2025-05-08	Ossifi Therapeutics Llc	Pyrrolo - dipyridine compounds
BR112021002655A2 (pt)	2018-08-14	2021-05-04	Osteoqc Inc.	compostos flúor ss-carbolina
US20230285376A1 (en)	2020-07-29	2023-09-14	Amryt Pharmaceuticals Inc.	Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3900261A1 (de) *	1988-05-31	1989-12-07	Bayer Ag	Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate
DE4200954A1 (de) *	1991-04-26	1992-10-29	Bayer Ag	Heterocyclisch substituierte phenylessigsaeurederivate
DE4208051A1 (de) *	1992-03-13	1993-09-16	Bayer Ag	Substituierte phenylessigsaeureamide
DE4302956A1 (de) *	1993-02-03	1994-08-04	Bayer Ag	Substituierte Imidazo(4,5-b)pyridine und Benzimidazole
DE4435477A1 (de) *	1994-10-04	1996-04-11	Bayer Ag	Cycloalkano-indol- und -azaindol-derivate

1996
- 1996-04-04 DE DE19613549A patent/DE19613549A1/de not_active Withdrawn
1997
- 1997-03-24 EP EP97104941A patent/EP0799829B1/de not_active Expired - Lifetime
- 1997-03-24 AT AT97104941T patent/ATE246193T1/de not_active IP Right Cessation
- 1997-03-24 DE DE59710487T patent/DE59710487D1/de not_active Expired - Lifetime
- 1997-03-24 ES ES97104941T patent/ES2202506T3/es not_active Expired - Lifetime
- 1997-03-27 NZ NZ314498A patent/NZ314498A/en unknown
- 1997-03-27 AU AU16602/97A patent/AU722592B2/en not_active Ceased
- 1997-03-28 HR HR19613549.4A patent/HRP970178A2/xx not_active Application Discontinuation
- 1997-03-31 US US08/829,566 patent/US5952498A/en not_active Expired - Lifetime
- 1997-03-31 ID IDP971060A patent/ID16794A/id unknown
- 1997-04-01 CA CA002201435A patent/CA2201435C/en not_active Expired - Fee Related
- 1997-04-01 JP JP09635197A patent/JP4235268B2/ja not_active Expired - Fee Related
- 1997-04-01 SG SG1997001028A patent/SG60050A1/en unknown
- 1997-04-01 MA MA24543A patent/MA24130A1/fr unknown
- 1997-04-02 DZ DZ970049A patent/DZ2202A1/fr active
- 1997-04-02 IL IL12059197A patent/IL120591A/xx not_active IP Right Cessation
- 1997-04-02 TN TNTNSN97060A patent/TNSN97060A1/fr unknown
- 1997-04-03 HU HU9700698A patent/HU218494B/hu not_active IP Right Cessation
- 1997-04-03 NO NO971513A patent/NO308301B1/no not_active IP Right Cessation
- 1997-04-03 PL PL97319269A patent/PL319269A1/xx unknown
- 1997-04-03 KR KR1019970012291A patent/KR970069988A/ko not_active Withdrawn
- 1997-04-03 EE EE9700079A patent/EE9700079A/xx unknown
- 1997-04-03 SK SK428-97A patent/SK42897A3/sk unknown
- 1997-04-03 ZA ZA9702831A patent/ZA972831B/xx unknown
- 1997-04-03 CZ CZ971021A patent/CZ102197A3/cs unknown
- 1997-04-04 AR ARP970101366A patent/AR006544A1/es unknown
- 1997-04-04 CN CN97110276A patent/CN1067394C/zh not_active Expired - Fee Related
- 1997-04-04 BR BR9701672A patent/BR9701672A/pt active Search and Examination
1998
- 1998-03-06 AR ARP980101029A patent/AR012048A2/es unknown
2000
- 2000-07-24 NO NO20003784A patent/NO20003784D0/no not_active Application Discontinuation
- 2000-10-12 CN CN00133103A patent/CN1330065A/zh active Pending
2008
- 2008-01-31 JP JP2008021569A patent/JP2008169218A/ja active Pending

Also Published As

Publication number	Publication date
CA2201435C (en)	2006-12-12
ATE246193T1 (de)	2003-08-15
DZ2202A1 (fr)	2002-12-03
HU218494B (hu)	2000-09-28
EE9700079A (et)	1997-10-15
SK42897A3 (en)	1997-10-08
PL319269A1 (en)	1997-10-13
AU1660297A (en)	1997-10-09
ES2202506T3 (es)	2004-04-01
NO971513L (no)	1997-10-06
HRP970178A2 (en)	1998-04-30
EP0799829A1 (de)	1997-10-08
NO971513D0 (no)	1997-04-03
JPH1045759A (ja)	1998-02-17
HUP9700698A1 (hu)	1998-01-28
BR9701672A (pt)	1998-11-03
ZA972831B (en)	1997-10-31
JP4235268B2 (ja)	2009-03-11
MX9702446A (es)	1997-10-31
IL120591A (en)	2000-11-21
KR970069988A (ko)	1997-11-07
CN1067394C (zh)	2001-06-20
MA24130A1 (fr)	1997-10-01
TNSN97060A1 (fr)	2005-03-15
DE59710487D1 (de)	2003-09-04
CA2201435A1 (en)	1997-10-04
JP2008169218A (ja)	2008-07-24
NO20003784D0 (no)	2000-07-24
AR006544A1 (es)	1999-09-08
EP0799829B1 (de)	2003-07-30
AU722592B2 (en)	2000-08-10
NZ314498A (en)	1999-09-29
CN1330065A (zh)	2002-01-09
DE19613549A1 (de)	1997-10-09
ID16794A (id)	1997-11-13
US5952498A (en)	1999-09-14
HU9700698D0 (en)	1997-05-28
IL120591A0 (en)	1997-08-14
NO20003784L (no)	1997-10-06
CZ102197A3 (en)	1997-10-15
SG60050A1 (en)	1999-02-22
AR012048A2 (es)	2000-09-27
CN1184109A (zh)	1998-06-10

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Legal Events

Date	Code	Title	Description
2002-12-09	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN OCTOBER 2002