NO20091260L - Kombinasjonsbehandling for diabetes mellitus - Google Patents
Kombinasjonsbehandling for diabetes mellitusInfo
- Publication number
- NO20091260L NO20091260L NO20091260A NO20091260A NO20091260L NO 20091260 L NO20091260 L NO 20091260L NO 20091260 A NO20091260 A NO 20091260A NO 20091260 A NO20091260 A NO 20091260A NO 20091260 L NO20091260 L NO 20091260L
- Authority
- NO
- Norway
- Prior art keywords
- diabetes mellitus
- combination therapy
- type
- hexahydrophenanthridine
- pyridin
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- NQMAAFUKIUCXHK-MZMPZRCHSA-N (2r,4ar,10br)-6-(2,6-dimethoxypyridin-3-yl)-9-ethoxy-8-methoxy-1,2,3,4,4a,10b-hexahydrophenanthridin-2-ol Chemical compound N([C@@H]1CC[C@@H](O)C[C@@H]1C=1C=C(C(=CC=11)OC)OCC)=C1C1=CC=C(OC)N=C1OC NQMAAFUKIUCXHK-MZMPZRCHSA-N 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Oppfinnelsen vedrører kombinasjoner av (2R,4aR,10bR)-6-(2,6-dimetoksy-pyridin-3-yl)- 9-etoksy-8-metoksy-1,2,3,4,4a,10b-heksahydrofenantridin-2-ol med andre aktive forbindelser for behandlingen av diabetes mellitus type 2 og/eller type 1.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06120305 | 2006-09-07 | ||
| PCT/EP2007/059253 WO2008028914A1 (en) | 2006-09-07 | 2007-09-04 | Combination treatment for diabetes mellitus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20091260L true NO20091260L (no) | 2009-03-26 |
Family
ID=38441474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20091260A NO20091260L (no) | 2006-09-07 | 2009-03-26 | Kombinasjonsbehandling for diabetes mellitus |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20100179131A1 (no) |
| EP (2) | EP2063890A1 (no) |
| JP (1) | JP2010502670A (no) |
| KR (1) | KR20090047546A (no) |
| CN (1) | CN101511364B (no) |
| AU (1) | AU2007293885A1 (no) |
| BR (1) | BRPI0716134A2 (no) |
| CA (1) | CA2662084A1 (no) |
| EA (1) | EA200900392A1 (no) |
| IL (1) | IL196869A0 (no) |
| ME (1) | MEP8509A (no) |
| MX (1) | MX2009002282A (no) |
| NO (1) | NO20091260L (no) |
| NZ (1) | NZ574710A (no) |
| UA (1) | UA100497C2 (no) |
| WO (1) | WO2008028914A1 (no) |
| ZA (1) | ZA200900501B (no) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2349324T3 (en) | 2008-10-17 | 2017-12-11 | Sanofi Aventis Deutschland | COMBINATION OF AN INSULIN AND A GLP-1 AGONIST |
| KR101836070B1 (ko) | 2009-11-13 | 2018-03-09 | 사노피-아벤티스 도이칠란트 게엠베하 | Glp-1 작용제, 인슐린 및 메티오닌을 포함하는 약제학적 조성물 |
| AU2009238272B2 (en) * | 2009-11-13 | 2014-05-08 | Sanofi-Aventis Deutschland Gmbh | Method of treatment of diabetes type 2 comprising add-on therapy to metformin |
| ES2965209T3 (es) | 2009-11-13 | 2024-04-11 | Sanofi Aventis Deutschland | Composición farmacéutica que comprende desPro36exendina-4(1-39)-Lys6-NH2 y metionina |
| JP5980466B2 (ja) * | 2009-11-13 | 2016-08-31 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | インスリングラルギン及びメトホルミンへの付加療法を含む2型糖尿病の治療方法 |
| AU2009238271B8 (en) * | 2009-11-13 | 2014-05-15 | Sanofi-Aventis Deutschland Gmbh | Method of treatment of diabetes type 2 comprising add-on therapy to insulin glargine and metformin |
| CN101747426B (zh) * | 2009-12-18 | 2013-01-16 | 深圳翰宇药业股份有限公司 | 一种合成普兰林肽的方法 |
| CN101798301A (zh) * | 2010-04-13 | 2010-08-11 | 漆又毛 | 吡咯烷基嘧啶甲磺酰胺衍生物及制备方法 |
| CN103179978A (zh) | 2010-08-30 | 2013-06-26 | 赛诺菲-安万特德国有限公司 | Ave0010用于制造供治疗2型糖尿病用的药物的用途 |
| TWI462739B (zh) * | 2010-11-02 | 2014-12-01 | Univ Kaohsiung Medical | Sildenafil-同族物四級銨哌嗪鹽類之製備及醫療用途 |
| TR201101809A1 (tr) * | 2010-12-21 | 2012-07-23 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Vildagliptin ve glimepirid kombinasyonları. |
| TR201107482A1 (tr) * | 2010-12-21 | 2012-07-23 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Vildagliptin ve gliklazidin iki tabakalı kombinasyon kompozisyonu. |
| EP2468268B1 (en) * | 2010-12-21 | 2017-12-13 | Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi | Combination composition of vildagliptin and gliclazide |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| ES2550357T3 (es) | 2011-08-29 | 2015-11-06 | Sanofi-Aventis Deutschland Gmbh | Combinación farmacéutica para su uso en el control glucémico en pacientes de diabetes de tipo 2 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| WO2014124860A1 (en) | 2013-02-14 | 2014-08-21 | Boehringer Ingelheim International Gmbh | Specific pde4b-inhibitors for the treatment of diabetes mellitus |
| US10132302B2 (en) * | 2013-07-22 | 2018-11-20 | Baxter International Inc. | Infusion pump including reverse loading protection |
| TWI668010B (zh) * | 2014-05-07 | 2019-08-11 | 丹麥商諾佛 儂迪克股份有限公司 | 使用glp-1及抗il-21治療糖尿病 |
| EP3151855B1 (en) * | 2014-06-08 | 2021-11-24 | REMD Biotherapeutics, Inc. | Methods for treating type 1 diabetes using glucagon receptor antagonistic antibodies |
| HRP20230470T1 (hr) | 2014-12-12 | 2023-07-21 | Sanofi-Aventis Deutschland Gmbh | Formulacija fiksnog omjera inzulin glargin/liksisenatid |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
| WO2018037109A1 (en) * | 2016-08-26 | 2018-03-01 | Takeda Gmbh | Treatment of nonalcoholic fatty liver disease |
| GB202306663D0 (en) * | 2023-05-05 | 2023-06-21 | Union Therapeutics As | Combination therapy |
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| US6417208B1 (en) | 1999-02-05 | 2002-07-09 | Albert Einstein College Of Medicine Of Yeshiva University | Method of identification of inhibitors of PDE1C |
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| SE9904413D0 (sv) | 1999-12-03 | 1999-12-03 | Astra Ab | Comminuted form |
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| UA74912C2 (en) | 2001-07-06 | 2006-02-15 | Merck & Co Inc | Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes |
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| BR0213817A (pt) | 2001-11-02 | 2004-10-19 | Pfizer Prod Inc | Tratamento de sìndrome de resistência à insulina e diabete do tipo 2 com inibidores da pde9 |
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| MXPA06014236A (es) | 2004-06-07 | 2007-02-14 | Pfizer Prod Inc | Inhibicion de la fosfodiesterasa 10 como tratamiento para las afecciones relacionadas con el sindrome metabolico y con la obesidad. |
| AU2006215444A1 (en) * | 2005-02-21 | 2006-08-24 | Sanofi-Aventis | Use of rimonabant for the preparation of medicaments that can be used in the prevention and treatment of type 2 diabetes |
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-
2007
- 2007-09-04 AU AU2007293885A patent/AU2007293885A1/en not_active Abandoned
- 2007-09-04 UA UAA200902891A patent/UA100497C2/ru unknown
- 2007-09-04 EP EP07803217A patent/EP2063890A1/en not_active Withdrawn
- 2007-09-04 WO PCT/EP2007/059253 patent/WO2008028914A1/en not_active Ceased
- 2007-09-04 BR BRPI0716134-4A2A patent/BRPI0716134A2/pt not_active IP Right Cessation
- 2007-09-04 MX MX2009002282A patent/MX2009002282A/es not_active Application Discontinuation
- 2007-09-04 ME MEP-85/09A patent/MEP8509A/xx unknown
- 2007-09-04 CN CN2007800332683A patent/CN101511364B/zh not_active Expired - Fee Related
- 2007-09-04 EP EP10005207A patent/EP2213289A1/en not_active Withdrawn
- 2007-09-04 JP JP2009527131A patent/JP2010502670A/ja active Pending
- 2007-09-04 CA CA002662084A patent/CA2662084A1/en not_active Abandoned
- 2007-09-04 KR KR1020097006219A patent/KR20090047546A/ko not_active Ceased
- 2007-09-04 US US12/310,547 patent/US20100179131A1/en not_active Abandoned
- 2007-09-04 NZ NZ574710A patent/NZ574710A/en not_active IP Right Cessation
- 2007-09-04 EA EA200900392A patent/EA200900392A1/ru unknown
-
2009
- 2009-01-22 ZA ZA2009/00501A patent/ZA200900501B/en unknown
- 2009-02-03 IL IL196869A patent/IL196869A0/en unknown
- 2009-03-26 NO NO20091260A patent/NO20091260L/no not_active Application Discontinuation
-
2012
- 2012-02-01 US US13/363,485 patent/US20120129817A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101511364A (zh) | 2009-08-19 |
| NZ574710A (en) | 2012-02-24 |
| EP2213289A1 (en) | 2010-08-04 |
| EP2063890A1 (en) | 2009-06-03 |
| US20100179131A1 (en) | 2010-07-15 |
| US20120129817A1 (en) | 2012-05-24 |
| WO2008028914A1 (en) | 2008-03-13 |
| CA2662084A1 (en) | 2008-03-13 |
| MEP8509A (en) | 2011-12-20 |
| AU2007293885A1 (en) | 2008-03-13 |
| KR20090047546A (ko) | 2009-05-12 |
| ZA200900501B (en) | 2010-02-24 |
| BRPI0716134A2 (pt) | 2013-09-17 |
| EA200900392A1 (ru) | 2010-06-30 |
| IL196869A0 (en) | 2009-11-18 |
| UA100497C2 (ru) | 2013-01-10 |
| MX2009002282A (es) | 2009-03-20 |
| JP2010502670A (ja) | 2010-01-28 |
| CN101511364B (zh) | 2012-08-15 |
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