NO20091783L - Middel for a forebygge/behandle kreft - Google Patents
Middel for a forebygge/behandle kreftInfo
- Publication number
- NO20091783L NO20091783L NO20091783A NO20091783A NO20091783L NO 20091783 L NO20091783 L NO 20091783L NO 20091783 A NO20091783 A NO 20091783A NO 20091783 A NO20091783 A NO 20091783A NO 20091783 L NO20091783 L NO 20091783L
- Authority
- NO
- Norway
- Prior art keywords
- cancer cells
- remedy
- preventing
- treating cancer
- seq
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 5
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 239000002254 cytotoxic agent Substances 0.000 abstract 1
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 1
- 239000003966 growth inhibitor Substances 0.000 abstract 1
- 230000009215 host defense mechanism Effects 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Pregnancy & Childbirth (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Sammendrag Et humant monoklonalt antistoff mot et protein som innbefatter den samme eller i det vesentlige den samme aminosyresekvensen som aminosyresekvensen representert ved SEQ ID NR: I eller SEQ ID NR: 3, dens delvise peptid, eller et salt derav, er anvendelig som et middel for hindring/behandling av kreft, etc., en apoptoseinduserer for kreftceller, en vekstinhiberer for kreftceller, et cytotoksisk middel mot kreftceller gjennom en vertsforsvarsmekanisme mediert av Fc-regionen til et antistoff, osv.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2006/320429 WO2007043635A1 (ja) | 2005-10-07 | 2006-10-06 | 癌の予防・治療剤 |
| ARP070101453A AR060362A1 (es) | 2005-10-07 | 2007-04-04 | Agente para prevenir / tratar el cancer |
| JP2007100876 | 2007-04-06 | ||
| PCT/JP2007/069908 WO2008044754A1 (en) | 2006-10-06 | 2007-10-04 | Prophylactic or therapeutic agent for cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20091783L true NO20091783L (no) | 2009-07-01 |
Family
ID=44083820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20091783A NO20091783L (no) | 2006-10-06 | 2009-05-05 | Middel for a forebygge/behandle kreft |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20100008928A1 (no) |
| EP (1) | EP2067791A4 (no) |
| JP (1) | JPWO2008044754A1 (no) |
| KR (1) | KR20090078339A (no) |
| CN (1) | CN101541834A (no) |
| AR (1) | AR063153A1 (no) |
| AU (1) | AU2007307536A1 (no) |
| BR (1) | BRPI0717024A2 (no) |
| CA (1) | CA2666249A1 (no) |
| CL (1) | CL2007002879A1 (no) |
| CO (1) | CO6190538A2 (no) |
| EC (1) | ECSP099276A (no) |
| IL (1) | IL197389A0 (no) |
| MA (1) | MA30816B1 (no) |
| MX (1) | MX2009003126A (no) |
| NO (1) | NO20091783L (no) |
| PE (1) | PE20081456A1 (no) |
| RU (1) | RU2009117237A (no) |
| TN (1) | TN2009000090A1 (no) |
| TW (1) | TW200823235A (no) |
| WO (1) | WO2008044754A1 (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012092374A2 (en) * | 2010-12-31 | 2012-07-05 | Short Jay M | Express humanization of antibodies |
| DK2740794T3 (en) * | 2011-08-04 | 2018-06-14 | Toray Industries | PHARMACEUTICAL COMPOSITION FOR TREATMENT AND / OR CANCER PREVENTION |
| EP3202419A1 (en) * | 2012-06-06 | 2017-08-09 | OncoMed Pharmaceuticals, Inc. | Pvrig binding agents that modulate the hippo pathway and uses thereof |
| WO2014069682A1 (ko) * | 2012-10-29 | 2014-05-08 | 인제대학교 산학협력단 | 암 표적 항체 및 이를 포함하는 암 예방 또는 치료용 조성물 |
| WO2014069681A1 (ko) * | 2012-10-29 | 2014-05-08 | 인제대학교 산학협력단 | 암 표적 항체 및 이를 포함하는 암 예방 또는 치료용 조성물 |
| WO2016134335A2 (en) | 2015-02-19 | 2016-08-25 | Compugen Ltd. | Pvrig polypeptides and methods of treatment |
| PL3653221T3 (pl) | 2015-02-19 | 2022-12-19 | Compugen Ltd. | Przeciwciała anty-pvrig i sposoby ich zastosowania |
| JO3620B1 (ar) * | 2015-08-05 | 2020-08-27 | Amgen Res Munich Gmbh | مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم |
| KR102585976B1 (ko) | 2016-08-17 | 2023-10-05 | 컴퓨젠 엘티디. | 항-tigit 항체, 항-pvrig 항체 및 이들의 조합 |
| RU2765410C2 (ru) | 2016-11-30 | 2022-01-28 | Онкомед Фармасьютикалс, Инк. | Способы лечения рака, включающие связывающие tigit агенты |
| US11225523B2 (en) | 2017-06-01 | 2022-01-18 | Compugen Ltd. | Triple combination antibody therapies |
| AU2019306628B2 (en) | 2018-07-20 | 2024-11-14 | Surface Oncology, LLC | Anti-CD112R compositions and methods |
| CN118878685A (zh) * | 2019-01-13 | 2024-11-01 | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 特异性针对人类连接蛋白-2的抗体 |
| CN113527486B (zh) * | 2020-04-21 | 2025-12-02 | 迈威(上海)生物科技股份有限公司 | 一种抗Nectin-4的抗体及其应用 |
| BR112023014128A2 (pt) | 2021-01-15 | 2023-10-31 | Seagen Inc | Conjugados de anticorpo-fármaco imunomodulatórios |
| JP2024506300A (ja) | 2021-02-03 | 2024-02-13 | シージェン インコーポレイテッド | 免疫刺激化合物及びコンジュゲート体 |
| WO2023161943A1 (en) * | 2022-02-28 | 2023-08-31 | Nectin Therapeutics Ltd. | Humanized antibodies against nectin-2 and drug conjugates thereof |
| CA3252067A1 (en) | 2022-05-06 | 2023-11-09 | Seagen Inc. | Immunomodulatory Antibody-Drug Conjugates |
| CA3262320A1 (en) | 2022-08-03 | 2024-02-08 | Regents Of The University Of Minnesota | Anti-PD-L1 Conjugates - Immunostimulating Drugs |
| EP4321522A1 (en) | 2022-08-12 | 2024-02-14 | Seagen Inc. | Cytotoxic compounds and conjugates thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE69133476T2 (de) | 1990-08-29 | 2006-01-05 | GenPharm International, Inc., Palo Alto | Transgene Mäuse fähig zur Produktion heterologer Antikörper |
| WO1999063063A1 (en) | 1998-06-03 | 1999-12-09 | Northwestern University | Cellular proteins which mediate herpesvirus entry |
| US20030129685A1 (en) * | 1998-10-28 | 2003-07-10 | Jian Ni | 12 human secreted proteins |
| DE19852800C1 (de) | 1998-11-16 | 2000-04-13 | Univ Albert Ludwigs Freiburg | Verfahren zur Herstellung von Antikörpern gegen ein Polypeptid, von dem die kodierende Nukleinsäure bekannt ist |
| US20030022279A1 (en) * | 1999-06-14 | 2003-01-30 | Fraser Christopher C. | Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses |
| WO2002000677A1 (en) | 2000-06-07 | 2002-01-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| MXPA03002479A (es) | 2000-10-05 | 2004-05-24 | Immunex Corp | Polipeptidos de nectina, polinucleotidos, metodos para elaborarlos y uso de los mismos. |
| EP1402058A4 (en) | 2001-06-05 | 2006-02-01 | Exelixis Inc | DGKS AS P53 PATH MODIFICATORS AND METHOD OF USE |
| CA2449303C (en) | 2001-06-06 | 2014-10-14 | Regeneron Pharmaceuticals, Inc. | Method for targeting transcriptionally active loci |
| US20030084468A1 (en) | 2001-09-05 | 2003-05-01 | Economides Aris N. | Methods of expressing transgenes |
| CA2481507A1 (en) * | 2002-04-16 | 2003-10-30 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US20070224201A1 (en) | 2002-10-02 | 2007-09-27 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| JPWO2005097204A1 (ja) * | 2004-04-09 | 2008-02-28 | 武田薬品工業株式会社 | 癌の予防・治療剤 |
-
2007
- 2007-10-04 EP EP07829644A patent/EP2067791A4/en not_active Withdrawn
- 2007-10-04 MX MX2009003126A patent/MX2009003126A/es not_active Application Discontinuation
- 2007-10-04 CN CNA2007800371476A patent/CN101541834A/zh active Pending
- 2007-10-04 WO PCT/JP2007/069908 patent/WO2008044754A1/ja not_active Ceased
- 2007-10-04 US US12/444,382 patent/US20100008928A1/en not_active Abandoned
- 2007-10-04 KR KR1020097009036A patent/KR20090078339A/ko not_active Withdrawn
- 2007-10-04 AU AU2007307536A patent/AU2007307536A1/en not_active Abandoned
- 2007-10-04 CA CA002666249A patent/CA2666249A1/en not_active Abandoned
- 2007-10-04 PE PE2007001348A patent/PE20081456A1/es not_active Application Discontinuation
- 2007-10-04 RU RU2009117237/10A patent/RU2009117237A/ru not_active Application Discontinuation
- 2007-10-04 JP JP2008538759A patent/JPWO2008044754A1/ja not_active Withdrawn
- 2007-10-04 BR BRPI0717024-6A2A patent/BRPI0717024A2/pt not_active IP Right Cessation
- 2007-10-05 TW TW096137411A patent/TW200823235A/zh unknown
- 2007-10-05 CL CL200702879A patent/CL2007002879A1/es unknown
- 2007-10-09 AR ARP070104425A patent/AR063153A1/es unknown
-
2009
- 2009-03-03 IL IL197389A patent/IL197389A0/en unknown
- 2009-03-16 TN TN2009000090A patent/TN2009000090A1/fr unknown
- 2009-04-23 EC EC2009009276A patent/ECSP099276A/es unknown
- 2009-04-27 MA MA31823A patent/MA30816B1/fr unknown
- 2009-05-04 CO CO09044621A patent/CO6190538A2/es not_active Application Discontinuation
- 2009-05-05 NO NO20091783A patent/NO20091783L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2008044754A1 (ja) | 2010-02-18 |
| MA30816B1 (fr) | 2009-10-01 |
| BRPI0717024A2 (pt) | 2014-03-11 |
| CL2007002879A1 (es) | 2008-06-27 |
| WO2008044754A1 (en) | 2008-04-17 |
| EP2067791A1 (en) | 2009-06-10 |
| PE20081456A1 (es) | 2008-11-27 |
| IL197389A0 (en) | 2011-08-01 |
| CO6190538A2 (es) | 2010-08-19 |
| EP2067791A4 (en) | 2009-11-25 |
| TN2009000090A1 (en) | 2010-08-19 |
| RU2009117237A (ru) | 2010-11-20 |
| MX2009003126A (es) | 2009-04-06 |
| CN101541834A (zh) | 2009-09-23 |
| US20100008928A1 (en) | 2010-01-14 |
| ECSP099276A (es) | 2009-06-30 |
| KR20090078339A (ko) | 2009-07-17 |
| AU2007307536A1 (en) | 2008-04-17 |
| AU2007307536A2 (en) | 2009-04-30 |
| AR063153A1 (es) | 2008-12-30 |
| TW200823235A (en) | 2008-06-01 |
| CA2666249A1 (en) | 2008-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |