MX2012008999A - Composicion farmaceutica para el tratamiento y/o prevencion del cancer. - Google Patents
Composicion farmaceutica para el tratamiento y/o prevencion del cancer.Info
- Publication number
- MX2012008999A MX2012008999A MX2012008999A MX2012008999A MX2012008999A MX 2012008999 A MX2012008999 A MX 2012008999A MX 2012008999 A MX2012008999 A MX 2012008999A MX 2012008999 A MX2012008999 A MX 2012008999A MX 2012008999 A MX2012008999 A MX 2012008999A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- antibody
- amino acid
- prevention
- acid sequence
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 6
- 201000011510 cancer Diseases 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102100029949 Caprin-1 Human genes 0.000 abstract 1
- 101710072528 Caprin-1 Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
De acuerdo con la invención actual, se identifica una proteína de antigeno de cáncer que se expresa específicamente en las superficies de células de cáncer y de esta manera se proporciona el uso de un anticuerpo que dirige la proteína de antígeno de cáncer como un agente para tratar y/o prevenir el cáncer. Específicamente, la invención actual proporciona una composición farmacéutica para tratar y/o prevenir un cáncer, que comprende un anticuerpo o un fragmento del mismo como un ingrediente activo que tiene reactividad inmunología con un péptido parcial de CAPRIN-1, que se representa por cualquiera de las secuencias de numeración uniforme de SEQ ID NOS: 2 hasta 30, en donde el polipéptido tiene la secuencia de aminoácidos que tiene 80% o más de identidad de secuencia con la secuencia de aminoácidos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010023451 | 2010-02-04 | ||
| PCT/JP2011/052403 WO2011096528A1 (ja) | 2010-02-04 | 2011-02-04 | 癌の治療及び／又は予防用医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012008999A true MX2012008999A (es) | 2012-08-31 |
| MX340014B MX340014B (es) | 2016-06-22 |
Family
ID=44355522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012008999A MX340014B (es) | 2010-02-04 | 2011-02-04 | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9115200B2 (es) |
| EP (1) | EP2532365B1 (es) |
| JP (1) | JP5742714B2 (es) |
| KR (1) | KR101842893B1 (es) |
| CN (1) | CN102821788B (es) |
| BR (1) | BR112012018947B8 (es) |
| CA (1) | CA2788715C (es) |
| DK (1) | DK2532365T3 (es) |
| ES (1) | ES2583627T3 (es) |
| HU (1) | HUE030103T2 (es) |
| MX (1) | MX340014B (es) |
| PL (1) | PL2532365T3 (es) |
| PT (1) | PT2532365T (es) |
| RU (1) | RU2607366C2 (es) |
| WO (1) | WO2011096528A1 (es) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2732980C (en) * | 2008-08-05 | 2017-08-15 | Toray Industries, Inc. | Caprin-1 as a target for diagnosing cancer |
| PL2322221T3 (pl) | 2008-08-05 | 2015-01-30 | Toray Industries | Kompozycja farmaceutyczna do leczenia i zapobiegania raka |
| PT2532366T (pt) | 2010-02-04 | 2016-12-20 | Toray Industries | Composição farmacêutica para o tratamento e/ou prevenção de cancro |
| DK2532680T3 (da) | 2010-02-04 | 2015-07-20 | Toray Industries | Medicinsk sammensætning til behandling og/eller forebyggelse af cancer |
| EP2532365B1 (en) | 2010-02-04 | 2016-05-04 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| CN102822335B (zh) | 2010-02-04 | 2015-09-30 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| ES2691738T3 (es) | 2010-02-04 | 2018-11-28 | Toray Industries, Inc. | Agente farmacéutico para el tratamiento y/o la prevención de cáncer |
| MX340016B (es) | 2010-02-04 | 2016-06-22 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| CN103717238B (zh) | 2011-08-04 | 2016-10-12 | 东丽株式会社 | 胰癌的治疗和/或预防用药物组合物 |
| HUE033628T2 (en) | 2011-08-04 | 2017-12-28 | Toray Industries | Method for detecting pancreatic cancer |
| US9180188B2 (en) | 2011-08-04 | 2015-11-10 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| PL2740794T3 (pl) | 2011-08-04 | 2018-09-28 | Toray Industries, Inc. | Kompozycja farmaceutyczna do leczenia i/lub profilaktyki nowotworów |
| CA2844038C (en) | 2011-08-04 | 2019-05-07 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| US9273128B2 (en) | 2011-08-04 | 2016-03-01 | Toray Industries, Inc | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| CN103764825B (zh) | 2011-08-04 | 2015-09-02 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| DK2818482T3 (da) * | 2012-02-21 | 2019-07-15 | Toray Industries | Farmaceutisk sammensætning til behandling af cancer |
| ES2739380T3 (es) * | 2012-02-21 | 2020-01-30 | Toray Industries | Composición farmacéutica para el tratamiento del cáncer |
| ES2643241T3 (es) | 2012-02-21 | 2017-11-21 | Toray Industries, Inc. | Composición medicinal para tratar y/o prevenir el cáncer |
| MX363136B (es) | 2012-02-21 | 2019-03-12 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| RU2640245C2 (ru) * | 2012-03-30 | 2017-12-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или предотвращения рака печени |
| JP6107655B2 (ja) * | 2012-03-30 | 2017-04-05 | 東レ株式会社 | 胆嚢癌の治療及び／又は予防用医薬組成物 |
| CN104471404B (zh) * | 2012-07-19 | 2017-03-01 | 东丽株式会社 | 癌的检测方法 |
| HUE043162T2 (hu) * | 2012-07-19 | 2019-08-28 | Toray Industries | Eljárás rák detektálására |
| CA2918989C (en) | 2013-08-09 | 2021-11-02 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| CN109069629B (zh) * | 2016-03-28 | 2023-02-24 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| CA3029902A1 (en) | 2016-07-07 | 2018-01-11 | The Board Of Trustees Of The Leland Stanford Junior University | Antibody adjuvant conjugates |
| EP3533466A4 (en) * | 2016-10-28 | 2020-06-10 | Toray Industries, Inc. | PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND / OR PREVENTION |
| EP3777888A4 (en) * | 2018-03-30 | 2021-12-01 | Toray Industries, Inc. | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND / OR PREVENTION OF CANCER |
| EP3924379A4 (en) | 2019-02-15 | 2022-12-21 | Integral Molecular, Inc. | COMMON LIGHT CHAIN ANTIBODIES AND THEIR USES |
| MX2021009831A (es) | 2019-02-15 | 2021-09-10 | Integral Molecular Inc | Anticuerpos claudina 6 y usos de los mismos. |
| CA3130794A1 (en) | 2019-03-15 | 2020-09-24 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
| BR112022018163A2 (pt) | 2020-03-12 | 2022-10-25 | Toray Industries | Medicamento para tratamento e/ou prevenção de câncer, agentes que aumentam a eficácia de droga de uma composição farmacêutica e método para tratar e/ou prevenir câncer |
| CA3175279A1 (en) | 2020-03-12 | 2021-09-16 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| KR20220152309A (ko) * | 2020-03-12 | 2022-11-15 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
| WO2021182573A1 (ja) | 2020-03-12 | 2021-09-16 | 東レ株式会社 | 癌の治療及び／又は予防のための医薬品 |
| KR20220153615A (ko) | 2020-03-12 | 2022-11-18 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
| US11768197B1 (en) * | 2021-06-19 | 2023-09-26 | Eggschain, Inc. | Rapid fertility and health indicator |
| EP4360648A4 (en) | 2021-06-23 | 2025-10-08 | Toray Industries | MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER |
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| AU2022316644A1 (en) | 2021-07-27 | 2024-02-29 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
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| US20250281630A1 (en) | 2021-09-03 | 2025-09-11 | Toray Industries, Inc. | Pharmaceutical composition for cancer treatment and/or prevention |
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| KR20250052368A (ko) | 2022-08-24 | 2025-04-18 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
| AU2023329563A1 (en) | 2022-08-24 | 2025-02-27 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| EP4578457A1 (en) | 2022-08-24 | 2025-07-02 | Toray Industries, Inc. | Pharmaceutical for treating and/or preventing cancer |
| CN119768184A (zh) | 2022-08-30 | 2025-04-04 | 东丽株式会社 | 用于癌的治疗和/或预防的药品 |
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| KR20250114330A (ko) | 2022-11-30 | 2025-07-29 | 인테그럴 몰큘러 인코포레이티드 | 클라우딘 6을 표적하는 항체 및 이의 이중특이적 형식 |
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- 2011-02-04 CA CA2788715A patent/CA2788715C/en active Active
- 2011-02-04 ES ES11739876.8T patent/ES2583627T3/es active Active
- 2011-02-04 PL PL11739876.8T patent/PL2532365T3/pl unknown
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- 2011-02-04 DK DK11739876.8T patent/DK2532365T3/en active
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- 2011-02-04 US US13/576,969 patent/US9115200B2/en active Active
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- 2011-02-04 CN CN201180017346.7A patent/CN102821788B/zh active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2532365B1 (en) | 2016-05-04 |
| BR112012018947B8 (pt) | 2020-06-02 |
| MX340014B (es) | 2016-06-22 |
| ES2583627T3 (es) | 2016-09-21 |
| AU2011211693A1 (en) | 2012-08-23 |
| EP2532365A1 (en) | 2012-12-12 |
| HUE030103T2 (en) | 2017-04-28 |
| CA2788715A1 (en) | 2011-08-11 |
| US9115200B2 (en) | 2015-08-25 |
| KR101842893B1 (ko) | 2018-03-28 |
| EP2532365A4 (en) | 2013-12-04 |
| JP5742714B2 (ja) | 2015-07-01 |
| DK2532365T3 (en) | 2016-08-15 |
| US20120301476A1 (en) | 2012-11-29 |
| RU2012137498A (ru) | 2014-03-10 |
| BR112012018947A8 (pt) | 2017-12-19 |
| PL2532365T3 (pl) | 2016-12-30 |
| CA2788715C (en) | 2021-06-08 |
| CN102821788B (zh) | 2016-11-16 |
| BR112012018947A2 (pt) | 2017-06-27 |
| KR20120123500A (ko) | 2012-11-08 |
| PT2532365T (pt) | 2016-07-28 |
| RU2607366C2 (ru) | 2017-01-10 |
| CN102821788A (zh) | 2012-12-12 |
| JPWO2011096528A1 (ja) | 2013-06-13 |
| WO2011096528A1 (ja) | 2011-08-11 |
| BR112012018947B1 (pt) | 2020-04-28 |
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