MX2012008998A - Composicion farmaceutica para el tratamiento y/o prevencion del cancer. - Google Patents
Composicion farmaceutica para el tratamiento y/o prevencion del cancer.Info
- Publication number
- MX2012008998A MX2012008998A MX2012008998A MX2012008998A MX2012008998A MX 2012008998 A MX2012008998 A MX 2012008998A MX 2012008998 A MX2012008998 A MX 2012008998A MX 2012008998 A MX2012008998 A MX 2012008998A MX 2012008998 A MX2012008998 A MX 2012008998A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- antibody
- amino acid
- prevention
- acid sequence
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 6
- 201000011510 cancer Diseases 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102100029949 Caprin-1 Human genes 0.000 abstract 1
- 101710072528 Caprin-1 Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
De acuerdo con la invención actual, se identifica una proteína de antigeno de cáncer que se expresa específicamente en las superficies de células de cáncer y de esta manera se proporciona el uso de un anticuerpo que dirige la proteína de antígeno de cáncer como un agente para tratar y/o prevenir el cáncer. Específicamente, la invención actual proporciona una composición farmacéutica para tratar y/o prevenir un cáncer, que comprende un anticuerpo o un fragmento del mismo como un ingrediente activo que tiene reactividad inmunología con un péptido parcial de CAPRIN-1, en donde CAPRIN-1 se representa por cualquiera de las secuencias de numeración uniforme de SEQ ID NOS: 2 hasta 30, y en donde el polipéptido parcial comprende la secuencia de aminoácidos representada por SEQ ID NO: 37 o una secuencia de aminoácidos que tiene 80% o más de identidad de secuencia con la secuencia de aminoácidos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010023454 | 2010-02-04 | ||
| JP2010183162 | 2010-08-18 | ||
| PCT/JP2011/052413 WO2011096534A1 (ja) | 2010-02-04 | 2011-02-04 | 癌の治療及び／又は予防用医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012008998A true MX2012008998A (es) | 2012-08-31 |
| MX340015B MX340015B (es) | 2016-06-22 |
Family
ID=44355528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012008998A MX340015B (es) | 2010-02-04 | 2011-02-04 | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8828398B2 (es) |
| EP (1) | EP2532743B1 (es) |
| JP (1) | JP5906739B2 (es) |
| KR (1) | KR101805520B1 (es) |
| CN (1) | CN102822335B (es) |
| AU (1) | AU2011211699B2 (es) |
| BR (1) | BR112012018949A2 (es) |
| CA (1) | CA2788718C (es) |
| ES (1) | ES2540858T3 (es) |
| MX (1) | MX340015B (es) |
| PL (1) | PL2532743T3 (es) |
| PT (1) | PT2532743E (es) |
| RU (1) | RU2603742C2 (es) |
| WO (1) | WO2011096534A1 (es) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2733492T3 (pl) * | 2008-08-05 | 2016-08-31 | Toray Industries | Sposób wykrywania nowotworów |
| US9416192B2 (en) | 2008-08-05 | 2016-08-16 | Toray Industries, Inc. | Pharmaceutical composition for treatment and prevention of cancers |
| JP5923985B2 (ja) | 2010-02-04 | 2016-05-25 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| RU2603742C2 (ru) | 2010-02-04 | 2016-11-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
| MX340014B (es) | 2010-02-04 | 2016-06-22 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
| EP2532367B1 (en) | 2010-02-04 | 2018-08-29 | Toray Industries, Inc. | Pharmaceutical agent for treatment and/or prevention of cancer |
| BR112012019098B8 (pt) | 2010-02-04 | 2021-08-17 | Toray Industries | anticorpo, composição farmacêutica, combinação farmacêutica e usos de um anticorpo, de uma composição farmacêutica e de uma combinação farmacêutica |
| CN102821789B (zh) | 2010-02-04 | 2016-03-02 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| ES2865068T3 (es) | 2011-01-14 | 2021-10-14 | Univ California | Anticuerpos terapéuticos contra la proteína ROR-1 y métodos para usarlos |
| JP6065591B2 (ja) | 2011-08-04 | 2017-01-25 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| WO2013018892A1 (ja) | 2011-08-04 | 2013-02-07 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| PL2740798T3 (pl) | 2011-08-04 | 2017-07-31 | Toray Industries, Inc. | Kompozycja leku do leczenia i/lub zapobiegania nowotworom |
| HUE033149T2 (en) | 2011-08-04 | 2017-11-28 | Toray Industries | A pharmaceutical composition for the treatment and / or prevention of cancer |
| KR102041832B1 (ko) | 2011-08-04 | 2019-11-08 | 도레이 카부시키가이샤 | 췌장암의 치료 및/또는 예방용 의약 조성물 |
| JP6094220B2 (ja) | 2011-08-04 | 2017-03-15 | 東レ株式会社 | 膵臓癌の検出方法 |
| DK2740794T3 (en) | 2011-08-04 | 2018-06-14 | Toray Industries | PHARMACEUTICAL COMPOSITION FOR TREATMENT AND / OR CANCER PREVENTION |
| JP6187255B2 (ja) * | 2012-02-21 | 2017-08-30 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| KR102009236B1 (ko) | 2012-02-21 | 2019-08-09 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방용 의약 조성물 |
| DK2818483T3 (en) | 2012-02-21 | 2017-10-23 | Toray Industries | Medical composition for the treatment and / or prevention of cancer |
| WO2013125630A1 (ja) | 2012-02-21 | 2013-08-29 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| ES2656620T3 (es) * | 2012-03-30 | 2018-02-27 | Toray Industries, Inc. | Composición farmacéutica para el tratamiento y/o la prevención del cáncer de hígado |
| HUE036425T2 (hu) | 2012-03-30 | 2018-07-30 | Toray Industries | Gyógyászati készítmény epehólyagrák kezelésére és/vagy megelõzésére |
| PL2876446T3 (pl) | 2012-07-19 | 2019-06-28 | Toray Industries, Inc. | Sposób wykrywania nowotworu |
| AU2013291051C1 (en) | 2012-07-19 | 2019-07-04 | Toray Industries, Inc. | Cancer detection method |
| EP3031826B1 (en) | 2013-08-09 | 2018-10-10 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| CN115317603A (zh) | 2016-07-07 | 2022-11-11 | 小利兰·斯坦福大学托管委员会 | 抗体佐剂缀合物 |
| US12274745B2 (en) | 2016-10-28 | 2025-04-15 | Toray Industries, Inc. | Conjugate of CAPRIN-1 antibody linked to immune activator for cancer treatment |
| KR101872193B1 (ko) | 2017-02-06 | 2018-08-03 | (주)엘에프라이팅 | 안정기함 |
| BR112020019935A2 (pt) | 2018-03-30 | 2021-01-26 | Toray Industries, Inc. | medicamento para o tratamento e/ou prevenção do câncer, agentes que aumentam a eficácia de um fármaco e método de tratamento e/ou prevenção do câncer |
| EP3937984A1 (en) | 2019-03-15 | 2022-01-19 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
| JPWO2021182574A1 (es) | 2020-03-12 | 2021-09-16 | ||
| JP7715041B2 (ja) * | 2020-03-12 | 2025-07-30 | 東レ株式会社 | 癌の治療及び／又は予防のための医薬品 |
| EP4119159A4 (en) | 2020-03-12 | 2024-03-27 | Toray Industries, Inc. | MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER |
| US20230139178A1 (en) * | 2020-03-12 | 2023-05-04 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| US20230129035A1 (en) | 2020-03-12 | 2023-04-27 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| KR20240024074A (ko) | 2021-06-23 | 2024-02-23 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
| MX2023014500A (es) | 2021-06-23 | 2024-01-25 | Toray Industries | Medicamento para el tratamiento y/o prevencion de cancer. |
| US20240301092A1 (en) * | 2021-06-29 | 2024-09-12 | Tega Therapeutics, Inc. | Heparin from modified mst cells and methods of making and using |
| AU2022320304A1 (en) | 2021-07-27 | 2024-02-29 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| EP4378477A4 (en) | 2021-07-27 | 2025-08-13 | Toray Industries | MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER |
| AU2022319362A1 (en) | 2021-07-27 | 2024-02-29 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| CA3230737A1 (en) | 2021-09-03 | 2023-03-09 | Toray Industries, Inc. | Pharmaceutical composition for cancer treatment and/or prevention |
| AU2023298568A1 (en) | 2022-06-30 | 2025-01-09 | Toray Industries, Inc. | Pharmaceutical composition for cancer treatment and/or prevention |
| AU2023329563A1 (en) | 2022-08-24 | 2025-02-27 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| CN119768182A (zh) | 2022-08-24 | 2025-04-04 | 东丽株式会社 | 用于癌的治疗和/或预防的药品 |
| JPWO2024043258A1 (es) | 2022-08-24 | 2024-02-29 | ||
| WO2024048541A1 (ja) | 2022-08-30 | 2024-03-07 | 東レ株式会社 | 癌の治療及び／又は予防のための医薬品 |
| AU2023334696A1 (en) | 2022-08-30 | 2025-02-27 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
| JPWO2024135809A1 (es) | 2022-12-23 | 2024-06-27 | ||
| WO2025058000A1 (ja) * | 2023-09-13 | 2025-03-20 | 東レ株式会社 | 癌の治療、予防及び／又は診断用医薬組成物 |
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-
2011
- 2011-02-04 RU RU2012137502/10A patent/RU2603742C2/ru active
- 2011-02-04 KR KR1020127022758A patent/KR101805520B1/ko active Active
- 2011-02-04 CA CA2788718A patent/CA2788718C/en active Active
- 2011-02-04 PL PL11739882T patent/PL2532743T3/pl unknown
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- 2011-02-04 EP EP11739882.6A patent/EP2532743B1/en active Active
- 2011-02-04 CN CN201180016730.5A patent/CN102822335B/zh active Active
- 2011-02-04 US US13/576,953 patent/US8828398B2/en active Active
- 2011-02-04 ES ES11739882.6T patent/ES2540858T3/es active Active
- 2011-02-04 PT PT117398826T patent/PT2532743E/pt unknown
- 2011-02-04 BR BR112012018949-2A patent/BR112012018949A2/pt not_active Application Discontinuation
- 2011-02-04 WO PCT/JP2011/052413 patent/WO2011096534A1/ja not_active Ceased
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Also Published As
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|---|---|
| BR112012018949A2 (pt) | 2020-09-01 |
| EP2532743B1 (en) | 2015-04-15 |
| CN102822335B (zh) | 2015-09-30 |
| PT2532743E (pt) | 2015-08-04 |
| AU2011211699B2 (en) | 2015-01-22 |
| US20140341919A1 (en) | 2014-11-20 |
| MX340015B (es) | 2016-06-22 |
| US20120301471A1 (en) | 2012-11-29 |
| US9416191B2 (en) | 2016-08-16 |
| RU2012137502A (ru) | 2014-03-10 |
| CA2788718A1 (en) | 2011-08-11 |
| RU2603742C2 (ru) | 2016-11-27 |
| PL2532743T3 (pl) | 2015-09-30 |
| ES2540858T3 (es) | 2015-07-14 |
| WO2011096534A1 (ja) | 2011-08-11 |
| KR20130004277A (ko) | 2013-01-09 |
| AU2011211699A1 (en) | 2012-08-23 |
| KR101805520B1 (ko) | 2017-12-07 |
| JPWO2011096534A1 (ja) | 2013-06-13 |
| EP2532743A4 (en) | 2013-09-11 |
| EP2532743A1 (en) | 2012-12-12 |
| CN102822335A (zh) | 2012-12-12 |
| JP5906739B2 (ja) | 2016-04-20 |
| CA2788718C (en) | 2019-05-21 |
| US8828398B2 (en) | 2014-09-09 |
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