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NO20081369L - Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika - Google Patents

Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika

Info

Publication number
NO20081369L
NO20081369L NO20081369A NO20081369A NO20081369L NO 20081369 L NO20081369 L NO 20081369L NO 20081369 A NO20081369 A NO 20081369A NO 20081369 A NO20081369 A NO 20081369A NO 20081369 L NO20081369 L NO 20081369L
Authority
NO
Norway
Prior art keywords
disorders
phenyl
processes
pyridinyl
pharmaceuticals
Prior art date
Application number
NO20081369A
Other languages
English (en)
Inventor
Patrick Bernardelli
Stefanie Keil
Matthias Urmann
Wolfgang Wendler
Maike Glien
Karen Chandross
Lan Lee
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35788653&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20081369(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20081369L publication Critical patent/NO20081369L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
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  • Obesity (AREA)
  • Cardiology (AREA)
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Abstract

Oppfinnelsen angår fenyl-l,2,4-oksadiazolonderivater i alle deres stereoisomere former og blandinger i et hvilket som helst forhold og deres fysiologisk akseptable salter og tautomere former som viser PPAR5-agonistaktivitet. Det som er beskrevet er forbindelser med formel (I) hvori radikalene er som definert, og deres fysiologisk akseptable salter og fremgangsmåter for deres fremstillinger. Forbindelsene er egnet for behandling og/eller hindring av forstyrrelser vedrørende fettsyremetabolisme og glukoseutnyttingsforstyrrelser, så vel som forstyrrelser hvori insulinresistens er involvert og demyelinerende og andre neurodegenerative forstyrrelser i det sentrale og periferale nervesystemet.
NO20081369A 2005-09-29 2008-03-14 Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika NO20081369L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05021277 2005-09-29
PCT/EP2006/009303 WO2007039177A2 (en) 2005-09-29 2006-09-26 Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
NO20081369L true NO20081369L (no) 2008-05-28

Family

ID=35788653

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081369A NO20081369L (no) 2005-09-29 2008-03-14 Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika

Country Status (23)

Country Link
US (1) US7709481B2 (no)
EP (1) EP1931337B1 (no)
JP (1) JP2009509988A (no)
KR (1) KR20080048504A (no)
CN (1) CN101272784A (no)
AR (1) AR056095A1 (no)
AU (1) AU2006299091A1 (no)
BR (1) BRPI0617207A2 (no)
CA (1) CA2624102A1 (no)
CR (1) CR9785A (no)
DO (1) DOP2006000203A (no)
EC (1) ECSP088322A (no)
IL (1) IL190231A0 (no)
MA (1) MA29805B1 (no)
NO (1) NO20081369L (no)
NZ (1) NZ566877A (no)
PE (1) PE20070620A1 (no)
RU (1) RU2008112198A (no)
TN (1) TNSN08148A1 (no)
TW (1) TW200806658A (no)
UY (1) UY29831A1 (no)
WO (1) WO2007039177A2 (no)
ZA (1) ZA200801629B (no)

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JP2012511525A (ja) 2008-12-11 2012-05-24 バイエル・クロップサイエンス・アーゲー 植物保護剤としてのチアゾリルオキシムエーテルおよびヒドラゾン
EP2198710A1 (de) 2008-12-19 2010-06-23 Bayer CropScience AG Verwendung von 5-Pyridin-4yl-(1,3)Thiazole zur Bekämpfung phytopathogener Pilze
CN102459222B (zh) * 2009-06-05 2014-06-04 辉瑞大药厂 用作gpr119 调节剂的l-(哌啶-4-基)-吡唑衍生物
WO2011041154A1 (en) 2009-10-01 2011-04-07 Metabolex, Inc. Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
CN107875155A (zh) 2009-10-08 2018-04-06 赛诺菲 苯基噁二唑衍生物在制备治疗变应性或炎性疾病的药物中的用途
CN102971314B (zh) 2010-04-28 2016-03-23 拜耳知识产权有限责任公司 酮基杂芳基哌啶和酮基杂芳基哌嗪衍生物作为杀菌剂
CN109674753A (zh) 2010-06-23 2019-04-26 希玛贝治疗股份有限公司 固态分散体
EP2532233A1 (en) 2011-06-07 2012-12-12 Bayer CropScience AG Active compound combinations
CN104640869B (zh) 2012-04-26 2017-12-12 百时美施贵宝公司 作为用于治疗血小板聚集的蛋白酶激活受体4(par4)抑制剂的咪唑并噻二唑和咪唑并哒嗪衍生物
CN104583218B (zh) 2012-04-26 2018-04-24 百时美施贵宝公司 作为蛋白酶活化受体4(par4)抑制剂用于治疗血小板聚集的咪唑并噻二唑和咪唑并吡嗪的衍生物
JP6181744B2 (ja) 2012-04-26 2017-08-16 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 血小板凝集を治療するためのプロテアーゼ活性化受容体４（ｐａｒ４）阻害剤としてのイミダゾチアジアゾール誘導体
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