NO20081368L - Derivater av 2-amintiazoler og 2-aminooksazoler, fremgangsmate for fremstilling derav samt deres anvendelse som farmasoytika - Google Patents
Derivater av 2-amintiazoler og 2-aminooksazoler, fremgangsmate for fremstilling derav samt deres anvendelse som farmasoytikaInfo
- Publication number
- NO20081368L NO20081368L NO20081368A NO20081368A NO20081368L NO 20081368 L NO20081368 L NO 20081368L NO 20081368 A NO20081368 A NO 20081368A NO 20081368 A NO20081368 A NO 20081368A NO 20081368 L NO20081368 L NO 20081368L
- Authority
- NO
- Norway
- Prior art keywords
- disorders
- aminoozazoles
- aminothiazoles
- derivatives
- processes
- Prior art date
Links
- RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical class NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000003210 demyelinating effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000004129 fatty acid metabolism Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Oppfinnelsen angår derivater av 2-aminotiazoler og 2-aminooksazoler i alle deres stereoisomere former, enantiomere former og blandinger i et hvilket som helst forhold og deres fysiologisk akseptable salter og tautomere former som viser PPAR5-agonist-aktivitet. Det som er beskrevet er forbindelser med formel I hvori radikalene er som definert og deres fysiologisk akseptable salter og fremgangsmåter for deres fremstilling. Forbindelsene er egnet for behandling og/eller hindring av forstyrrelser vedrørende fettsyremetabolismen og glukoseutnyttingsforstyrrelser, så vel som forstyrrelser hvori insulinresistens er involvert og demyelinerende og andre neurodegenerative forstyrrelser vedrørende det sentrale og periferale nervesystemet.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05021279 | 2005-09-29 | ||
| PCT/EP2006/009302 WO2007039176A1 (en) | 2005-09-29 | 2006-09-26 | Derivatives of 2 -aminthiazoles and 2-aminooxazoles, processes for their preparation and their use as pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20081368L true NO20081368L (no) | 2008-06-18 |
Family
ID=35764446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20081368A NO20081368L (no) | 2005-09-29 | 2008-03-14 | Derivater av 2-amintiazoler og 2-aminooksazoler, fremgangsmate for fremstilling derav samt deres anvendelse som farmasoytika |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7655679B2 (no) |
| EP (1) | EP1931659B1 (no) |
| JP (1) | JP2009509987A (no) |
| KR (1) | KR20080048510A (no) |
| CN (1) | CN101277953A (no) |
| AR (1) | AR056542A1 (no) |
| AT (1) | ATE480536T1 (no) |
| AU (1) | AU2006299090A1 (no) |
| BR (1) | BRPI0616477A2 (no) |
| CA (1) | CA2624100A1 (no) |
| DE (1) | DE602006016830D1 (no) |
| IL (1) | IL190230A0 (no) |
| MA (1) | MA29806B1 (no) |
| MY (1) | MY148883A (no) |
| NO (1) | NO20081368L (no) |
| NZ (1) | NZ566876A (no) |
| RU (1) | RU2008112199A (no) |
| TW (1) | TW200732328A (no) |
| UY (1) | UY29832A1 (no) |
| WO (1) | WO2007039176A1 (no) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE521605T1 (de) | 2007-11-20 | 2011-09-15 | Sumitomo Chemical Co | Pyridinverbindung, schädlingsbekämpfungsmittel und verfahren zur bekämpfung von schädlingen |
| US9073881B2 (en) | 2011-09-23 | 2015-07-07 | Hoffmann-La Roche Inc. | Benzoic acid derivatives |
| WO2013066839A2 (en) * | 2011-10-31 | 2013-05-10 | Glaxosmithkline Llc | Compounds and methods |
| EP3976053A4 (en) * | 2019-05-31 | 2022-11-23 | Avolynt | COMPOSITIONS AND METHODS FOR TREATMENT OF METABOLIC DISEASES |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641796A (en) | 1994-11-01 | 1997-06-24 | Eli Lilly And Company | Oral hypoglycemic agents |
| GB9919413D0 (en) | 1999-08-18 | 1999-10-20 | Zeneca Ltd | Chemical compounds |
| JP4383177B2 (ja) * | 2002-03-01 | 2009-12-16 | スミスクライン ビーチャム コーポレーション | ｈＰＰＡＲ活性化剤 |
| US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
| EP1586573B1 (en) | 2004-04-01 | 2007-02-07 | Sanofi-Aventis Deutschland GmbH | Oxadiazolones, processes for their preparation and their use as pharmaceuticals |
-
2006
- 2006-09-26 KR KR1020087007472A patent/KR20080048510A/ko not_active Withdrawn
- 2006-09-26 BR BRPI0616477-3A patent/BRPI0616477A2/pt not_active IP Right Cessation
- 2006-09-26 WO PCT/EP2006/009302 patent/WO2007039176A1/en not_active Ceased
- 2006-09-26 AU AU2006299090A patent/AU2006299090A1/en not_active Abandoned
- 2006-09-26 EP EP06792250A patent/EP1931659B1/en active Active
- 2006-09-26 NZ NZ566876A patent/NZ566876A/en not_active IP Right Cessation
- 2006-09-26 DE DE602006016830T patent/DE602006016830D1/de active Active
- 2006-09-26 JP JP2008532646A patent/JP2009509987A/ja not_active Abandoned
- 2006-09-26 CA CA002624100A patent/CA2624100A1/en not_active Abandoned
- 2006-09-26 CN CNA2006800360458A patent/CN101277953A/zh active Pending
- 2006-09-26 RU RU2008112199/04A patent/RU2008112199A/ru not_active Application Discontinuation
- 2006-09-26 AT AT06792250T patent/ATE480536T1/de not_active IP Right Cessation
- 2006-09-27 TW TW095135659A patent/TW200732328A/zh unknown
- 2006-09-27 AR ARP060104224A patent/AR056542A1/es not_active Application Discontinuation
- 2006-09-27 MY MYPI20064226A patent/MY148883A/en unknown
- 2006-09-29 UY UY29832A patent/UY29832A1/es not_active Application Discontinuation
-
2008
- 2008-03-14 NO NO20081368A patent/NO20081368L/no not_active Application Discontinuation
- 2008-03-17 IL IL190230A patent/IL190230A0/en unknown
- 2008-03-24 MA MA30782A patent/MA29806B1/fr unknown
- 2008-03-26 US US12/055,771 patent/US7655679B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006299090A1 (en) | 2007-04-12 |
| US20080227834A1 (en) | 2008-09-18 |
| ATE480536T1 (de) | 2010-09-15 |
| CN101277953A (zh) | 2008-10-01 |
| EP1931659B1 (en) | 2010-09-08 |
| JP2009509987A (ja) | 2009-03-12 |
| RU2008112199A (ru) | 2009-10-10 |
| NZ566876A (en) | 2010-05-28 |
| DE602006016830D1 (de) | 2010-10-21 |
| AR056542A1 (es) | 2007-10-10 |
| BRPI0616477A2 (pt) | 2011-06-21 |
| MY148883A (en) | 2013-06-14 |
| UY29832A1 (es) | 2007-04-30 |
| CA2624100A1 (en) | 2007-04-12 |
| EP1931659A1 (en) | 2008-06-18 |
| MA29806B1 (fr) | 2008-09-01 |
| WO2007039176A1 (en) | 2007-04-12 |
| IL190230A0 (en) | 2008-11-03 |
| KR20080048510A (ko) | 2008-06-02 |
| TW200732328A (en) | 2007-09-01 |
| US7655679B2 (en) | 2010-02-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |