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NO20080133L - Azolopyridin-2-on derivater som lipase og fosfolipaseinhibitorer - Google Patents

Azolopyridin-2-on derivater som lipase og fosfolipaseinhibitorer

Info

Publication number
NO20080133L
NO20080133L NO20080133A NO20080133A NO20080133L NO 20080133 L NO20080133 L NO 20080133L NO 20080133 A NO20080133 A NO 20080133A NO 20080133 A NO20080133 A NO 20080133A NO 20080133 L NO20080133 L NO 20080133L
Authority
NO
Norway
Prior art keywords
azolopyridin
derivatives
lipase
phospholipase inhibitors
phospholipase
Prior art date
Application number
NO20080133A
Other languages
English (en)
Inventor
Hubert Heuer
Gerhard Zoller
Stefan Petry
Guenter Mueller
Norbert Tennagels
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20080133L publication Critical patent/NO20080133L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Det er beskrevet azolopyridin-2-on-derivater av generell formel (1) med betydningene angitt i beskrivelsen, farmasøytisk anvendbare salter derav, og anvendelsen derav som medisinske stoffer.
NO20080133A 2005-06-09 2008-01-08 Azolopyridin-2-on derivater som lipase og fosfolipaseinhibitorer NO20080133L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005026762A DE102005026762A1 (de) 2005-06-09 2005-06-09 Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
PCT/EP2006/005095 WO2006131231A1 (de) 2005-06-09 2006-05-27 Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen

Publications (1)

Publication Number Publication Date
NO20080133L true NO20080133L (no) 2008-03-05

Family

ID=37076291

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080133A NO20080133L (no) 2005-06-09 2008-01-08 Azolopyridin-2-on derivater som lipase og fosfolipaseinhibitorer

Country Status (30)

Country Link
US (2) US7846943B2 (no)
EP (1) EP1896485B1 (no)
JP (1) JP2008542410A (no)
KR (1) KR20080019215A (no)
CN (1) CN101193896A (no)
AR (1) AR054132A1 (no)
AT (1) ATE468342T1 (no)
AU (1) AU2006257022A1 (no)
BR (1) BRPI0611688A2 (no)
CA (1) CA2610325A1 (no)
CY (1) CY1110213T1 (no)
DE (2) DE102005026762A1 (no)
DK (1) DK1896485T3 (no)
ES (1) ES2346561T3 (no)
HR (1) HRP20100409T1 (no)
IL (1) IL187730A0 (no)
MA (1) MA29481B1 (no)
MX (1) MX2007015347A (no)
MY (1) MY142792A (no)
NO (1) NO20080133L (no)
NZ (1) NZ564063A (no)
PL (1) PL1896485T3 (no)
PT (1) PT1896485E (no)
RS (1) RS51268B (no)
RU (1) RU2414473C2 (no)
SI (1) SI1896485T1 (no)
TW (1) TW200716653A (no)
UY (1) UY29593A1 (no)
WO (1) WO2006131231A1 (no)
ZA (1) ZA200709501B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006014685A1 (de) 2006-03-28 2007-10-04 Sanofi-Aventis Imidazo-pyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholiphasen
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP2310372B1 (en) 2008-07-09 2012-05-23 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
US8957219B2 (en) 2008-10-17 2015-02-17 Shionogi & Co., Ltd. Acetic acid amide derivative having inhibitory activity on endothelial lipase
CN102725291B (zh) * 2009-10-29 2016-12-21 西特里斯药业公司 作为沉默调节蛋白调节剂的双环吡啶和相关的类似物
CN102753545A (zh) 2009-12-15 2012-10-24 盐野义制药株式会社 具有血管内皮脂酶抑制活性的噁二唑衍生物
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
CN114560873B (zh) * 2021-12-27 2023-02-28 浙江日出药业有限公司 一种3-氯甲基-6-氯-噁唑[4,5-b]吡啶-2(3H)酮的制备方法

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Also Published As

Publication number Publication date
AR054132A1 (es) 2007-06-06
BRPI0611688A2 (pt) 2010-09-28
RU2414473C2 (ru) 2011-03-20
SI1896485T1 (sl) 2010-09-30
MY142792A (en) 2010-12-31
DE502006006986D1 (de) 2010-07-01
RS51268B (sr) 2010-12-31
RU2007145499A (ru) 2009-06-20
AU2006257022A1 (en) 2006-12-14
US20110039883A1 (en) 2011-02-17
ES2346561T3 (es) 2010-10-18
TW200716653A (en) 2007-05-01
EP1896485B1 (de) 2010-05-19
EP1896485A1 (de) 2008-03-12
US20080167339A1 (en) 2008-07-10
KR20080019215A (ko) 2008-03-03
CY1110213T1 (el) 2012-05-23
NZ564063A (en) 2010-07-30
CA2610325A1 (en) 2006-12-14
CN101193896A (zh) 2008-06-04
DE102005026762A1 (de) 2006-12-21
ATE468342T1 (de) 2010-06-15
JP2008542410A (ja) 2008-11-27
UY29593A1 (es) 2007-01-31
PT1896485E (pt) 2010-08-05
IL187730A0 (en) 2008-08-07
WO2006131231A1 (de) 2006-12-14
DK1896485T3 (da) 2010-09-06
US7846943B2 (en) 2010-12-07
MA29481B1 (fr) 2008-05-02
PL1896485T3 (pl) 2010-10-29
ZA200709501B (en) 2008-10-29
MX2007015347A (es) 2008-02-15
HRP20100409T1 (hr) 2010-09-30

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