[go: up one dir, main page]

NO20090346L - Pyrazolderivater som inhibitorer av cytokrom P450 - Google Patents

Pyrazolderivater som inhibitorer av cytokrom P450

Info

Publication number
NO20090346L
NO20090346L NO20090346A NO20090346A NO20090346L NO 20090346 L NO20090346 L NO 20090346L NO 20090346 A NO20090346 A NO 20090346A NO 20090346 A NO20090346 A NO 20090346A NO 20090346 L NO20090346 L NO 20090346L
Authority
NO
Norway
Prior art keywords
cytochrome
inhibitors
pyrazole derivatives
processes
solvates
Prior art date
Application number
NO20090346A
Other languages
English (en)
Inventor
Simon Paul Planken
Scott Channing Sutton
Rongliang Chen
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20090346L publication Critical patent/NO20090346L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Det beskrives forbindelser av formel (I), eller farmasøytisk akseptable salter eller solvater derav, fremgangsmåter for fremstilling av disse, fremgangsmåter for anvendelse av disse, og farmasøytiske formuleringer omfattende samme.
NO20090346A 2006-07-05 2009-01-22 Pyrazolderivater som inhibitorer av cytokrom P450 NO20090346L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80659606P 2006-07-05 2006-07-05
US91098807P 2007-04-10 2007-04-10
US94180807P 2007-06-04 2007-06-04
PCT/IB2007/001878 WO2008004096A1 (en) 2006-07-05 2007-06-25 Pyrazole derivatives as cytochrome p450 inhibitors

Publications (1)

Publication Number Publication Date
NO20090346L true NO20090346L (no) 2009-02-19

Family

ID=38515807

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090346A NO20090346L (no) 2006-07-05 2009-01-22 Pyrazolderivater som inhibitorer av cytokrom P450

Country Status (24)

Country Link
US (1) US7919488B2 (no)
EP (1) EP2046774A1 (no)
KR (1) KR20090034958A (no)
CN (1) CN101511812A (no)
AP (1) AP2009004763A0 (no)
AR (1) AR062154A1 (no)
AU (1) AU2007270814B2 (no)
CA (1) CA2660031A1 (no)
CO (1) CO6150178A2 (no)
CR (1) CR10573A (no)
EA (1) EA200900135A1 (no)
GT (1) GT200700053A (no)
IL (1) IL196490A0 (no)
MA (1) MA30629B1 (no)
MX (1) MX2009000482A (no)
NO (1) NO20090346L (no)
NZ (1) NZ574207A (no)
PE (1) PE20080998A1 (no)
RS (1) RS20090036A (no)
TN (1) TN2009000033A1 (no)
TW (1) TWI334867B (no)
UY (1) UY30460A1 (no)
WO (1) WO2008004096A1 (no)
ZA (1) ZA200900478B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8754107B2 (en) * 2006-11-17 2014-06-17 Abbvie Inc. Aminopyrrolidines as chemokine receptor antagonists
EP2132176A1 (en) * 2007-03-13 2009-12-16 Arete Therapeutics, Inc. 4-piperidinylurea compounds as soluble epoxide hydrolase inhibitors
EP2257536A4 (en) 2008-02-14 2011-03-23 Amira Pharmaceuticals Inc CYCLIC DIARYL ETHERS AS ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS
JP2011518130A (ja) 2008-04-02 2011-06-23 アミラ ファーマシューティカルズ，インク． プロスタグランジンｄ２受容体のアミノアルキルフェニルアンタゴニスト
DE102008057343A1 (de) 2008-11-14 2010-05-20 Bayer Schering Pharma Aktiengesellschaft Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung
DE102008057344A1 (de) 2008-11-14 2010-05-20 Bayer Schering Pharma Aktiengesellschaft Aminoalkyl-substituierte Aryl-Verbindungen und ihre Verwendung
DE102009041241A1 (de) 2009-09-11 2011-08-04 Bayer Schering Pharma Aktiengesellschaft, 13353 Substituierte Aryl-Verbindungen und ihre Verwendung
DE102009041242A1 (de) 2009-09-11 2011-12-15 Bayer Schering Pharma Aktiengesellschaft Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung
DE102008057364A1 (de) 2008-11-14 2010-05-20 Bayer Schering Pharma Aktiengesellschaft Substituierte Aryl-Verbindungen und ihre Verwendung
WO2010057118A2 (en) 2008-11-17 2010-05-20 Amira Pharmaceuticals, Inc. Heterocyclic antagonists of prostaglandin d2 receptors
CN107021951B (zh) 2010-06-30 2020-10-20 赛克里翁治疗有限公司 sGC刺激物
ES2572803T3 (es) 2010-11-09 2016-06-02 Ironwood Pharmaceuticals, Inc. Estimuladores de GCs
EP3112363A1 (en) 2011-12-27 2017-01-04 Ironwood Pharmaceuticals, Inc. 2-[1-[(2-fluorophenyl)methyl]-5-(3-isoxazolyl)-1h-pyrazol-3-yl]-pyrimidine derivatives and related compounds as soluble guanylate cyclase (sgc) stimulators for the treatment of pulmonary hypertension
CN104540813A (zh) * 2012-06-27 2015-04-22 默沙东公司 磺酰胺衍生物以及使用它们用于改善药物的药物动力学的方法
WO2014000178A1 (en) 2012-06-27 2014-01-03 Merck Sharp & Dohme Corp. Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug
WO2014194519A1 (en) * 2013-06-07 2014-12-11 Merck Sharp & Dohme Corp. Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug
WO2015070366A1 (en) 2013-11-12 2015-05-21 Merck Sharp & Dohme Corp. Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
WO2015070367A1 (en) 2013-11-12 2015-05-21 Merck Sharp & Dohme Corp. Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0024795D0 (en) 2000-10-10 2000-11-22 Hoffmann La Roche Pyrazole derivatives for the treatment of viral diseases
CA2439593C (en) * 2001-04-05 2010-02-09 Torrent Pharmaceuticals Ltd. Heterocyclic compounds for aging-related and diabetic vascular complications
US7008953B2 (en) * 2003-07-30 2006-03-07 Agouron Pharmaceuticals, Inc. 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
US7662844B2 (en) * 2004-07-12 2010-02-16 Osi Pharmaceuticals, Inc. Naphthylene derivatives as cytochrome P450 inhibitors
SI1937639T1 (sl) 2005-09-23 2010-07-30 Pfizer Prod Inc S piridinaminosulfonilom substituirani benzamidi kot inhibitorji citokromov P450

Also Published As

Publication number Publication date
US7919488B2 (en) 2011-04-05
US20080021011A1 (en) 2008-01-24
AP2009004763A0 (en) 2009-02-28
GT200700053A (es) 2009-08-03
TW200811159A (en) 2008-03-01
EP2046774A1 (en) 2009-04-15
TN2009000033A1 (fr) 2010-08-19
CO6150178A2 (es) 2010-04-20
CN101511812A (zh) 2009-08-19
IL196490A0 (en) 2011-07-31
UY30460A1 (es) 2008-02-29
AU2007270814A1 (en) 2008-01-10
PE20080998A1 (es) 2008-08-15
KR20090034958A (ko) 2009-04-08
RS20090036A (sr) 2010-06-30
MA30629B1 (fr) 2009-08-03
ZA200900478B (en) 2010-04-28
NZ574207A (en) 2010-10-29
TWI334867B (en) 2010-12-21
AR062154A1 (es) 2008-10-22
WO2008004096A1 (en) 2008-01-10
CR10573A (es) 2009-02-12
CA2660031A1 (en) 2008-01-10
MX2009000482A (es) 2009-01-27
AU2007270814B2 (en) 2011-07-14
EA200900135A1 (ru) 2009-06-30

Similar Documents

Publication Publication Date Title
NO20090346L (no) Pyrazolderivater som inhibitorer av cytokrom P450
WO2007087548A3 (en) Chemical compounds
NO20090628L (no) Pyridizinon derivativater
NO20081554L (no) Isoindollmidforbindelser og sammensetninger omfattende samme, og anvendelse derav
IL189666A0 (en) Pyridinaminosulfonyl substituted benzamides as inhibitors of cytochrome p450 3a4 (cyp3a4)
NO20091893L (no) Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav.
NO20066055L (no) Pyridinderivater
NO20090295L (no) Substituerte heteroarylderivater
MX2009003038A (es) Derivados de quinazolinona 5-sustituidos como agentes antitumorales.
NO20083863L (no) Pyrazoler som 11-beta-hsd-1
NO20092723L (no) Indazolylester og amidderivater for behandling av gluccocorticoid reseptormedierte sykdommer
NO20074703L (no) Antibakterielle piperidinderivater
MX2009008540A (es) Inhibidores de virus de hepatitis c macrociclicos sustituidos con pirimidina.
PL1899329T3 (pl) Pirymidyno-podstawione pochodne benzimidazolu jako inhibitory kinaz białkowych
NO20083246L (no) Nye benzimidazolderivater som vanilloid-reseptor 1 (VRL) inhibitorer
NO20082256L (no) Pyrazolderivater, preparater som inneholder slike forbindelser, og fremgangsmåter for anvendelse
NO20092058L (no) Heteroaryl pyrrolidinyl ketonderivater
NO20080035L (no) Benzooksazol-2-on derivater som lipase og fosfolipaseinhibitorer
NO20080133L (no) Azolopyridin-2-on derivater som lipase og fosfolipaseinhibitorer
NO20080110L (no) Benzimidazolderivativer som 5-HT6,5-HT24
UA90285C2 (ru) Производные гидантоина, полезные как ингибиторы металлопротеиназ
NO20080034L (no) Benzotiazol-2-on derivater som lipase og fosfolipaseinhibitorer
WO2008004100A3 (en) Therapeutic compounds
NO20065231L (no) Nye imidazoler
WO2008039894A3 (en) Atorvastatin pharmaceutical compositions

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application