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NO20076137L - Nye 2-azetidinonderivater og deres anvendelse som kolestrolabsorpsjonsinhibitorer for behandling av hyperlipidemi - Google Patents

Nye 2-azetidinonderivater og deres anvendelse som kolestrolabsorpsjonsinhibitorer for behandling av hyperlipidemi

Info

Publication number
NO20076137L
NO20076137L NO20076137A NO20076137A NO20076137L NO 20076137 L NO20076137 L NO 20076137L NO 20076137 A NO20076137 A NO 20076137A NO 20076137 A NO20076137 A NO 20076137A NO 20076137 L NO20076137 L NO 20076137L
Authority
NO
Norway
Prior art keywords
hyperlipidemia
treatment
cholesterol absorption
new
absorption inhibitors
Prior art date
Application number
NO20076137A
Other languages
English (en)
Inventor
Mikael Dahlstrom
Ann-Margret Lindqvist
Suzanne Alenfalk
Tore Skjaret
Malin Lemurell
Ingemar Starke
Fana Hunegnaw
Staffan Karlsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37570721&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20076137(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20076137L publication Critical patent/NO20076137L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Forbindelser med formel (I): (I) (hvor variable grupper er som definert) farmasøytisk akseptable salter, solvater, solvater av slike salter og prodrug derav og anvendelse av dem som kolesterolabsorpsjonsinhibitorer for behandling av hyperlipidemi er beskrevet. Prosesser for fremstilling av dem og farmasøytiske preparater inneholdende dem er også beskrevet.
NO20076137A 2005-06-20 2007-11-28 Nye 2-azetidinonderivater og deres anvendelse som kolestrolabsorpsjonsinhibitorer for behandling av hyperlipidemi NO20076137L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0501425 2005-06-20
PCT/SE2006/000741 WO2006137782A1 (en) 2005-06-20 2006-06-19 Novel 2-azetidinone derivatives and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia

Publications (1)

Publication Number Publication Date
NO20076137L true NO20076137L (no) 2008-01-18

Family

ID=37570721

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076137A NO20076137L (no) 2005-06-20 2007-11-28 Nye 2-azetidinonderivater og deres anvendelse som kolestrolabsorpsjonsinhibitorer for behandling av hyperlipidemi

Country Status (18)

Country Link
US (1) US7863265B2 (no)
EP (1) EP1896407A4 (no)
JP (1) JP2008546766A (no)
KR (1) KR20080019710A (no)
CN (1) CN101228123A (no)
AR (1) AR054484A1 (no)
AU (1) AU2006259949A1 (no)
BR (1) BRPI0612254A2 (no)
CA (1) CA2610890A1 (no)
EC (1) ECSP088114A (no)
IL (1) IL187736A0 (no)
MX (1) MX2007016483A (no)
NO (1) NO20076137L (no)
RU (1) RU2007147338A (no)
TW (1) TW200730493A (no)
UY (1) UY29607A1 (no)
WO (1) WO2006137782A1 (no)
ZA (1) ZA200710415B (no)

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Also Published As

Publication number Publication date
US7863265B2 (en) 2011-01-04
EP1896407A1 (en) 2008-03-12
EP1896407A4 (en) 2010-06-16
ZA200710415B (en) 2008-10-29
ECSP088114A (es) 2008-02-20
BRPI0612254A2 (pt) 2016-09-06
US20100216759A1 (en) 2010-08-26
KR20080019710A (ko) 2008-03-04
TW200730493A (en) 2007-08-16
JP2008546766A (ja) 2008-12-25
AU2006259949A1 (en) 2006-12-28
CN101228123A (zh) 2008-07-23
MX2007016483A (es) 2008-03-10
RU2007147338A (ru) 2009-07-27
UY29607A1 (es) 2007-01-31
IL187736A0 (en) 2008-08-07
AR054484A1 (es) 2007-06-27
WO2006137782A1 (en) 2006-12-28
CA2610890A1 (en) 2006-12-28

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