NO20076467L - Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner - Google Patents
Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteinerInfo
- Publication number
- NO20076467L NO20076467L NO20076467A NO20076467A NO20076467L NO 20076467 L NO20076467 L NO 20076467L NO 20076467 A NO20076467 A NO 20076467A NO 20076467 A NO20076467 A NO 20076467A NO 20076467 L NO20076467 L NO 20076467L
- Authority
- NO
- Norway
- Prior art keywords
- hiv
- derivative
- tat
- proteins
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- AIDS & HIV (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Oppfinnelsen tilveiebringer (a) et HIV-Tat-protein eller derivat derav koblet til enten (i) en fusjonspartner eller (ii) et HTV Nef-protein eller derivat derav; eller (b) et HTV Nef-protein eller derivat derav koblet til enten (i) en fusjonspartner eller (ii) et HIV-Tat-protein eller derivat derav; eller (c) et HTV-Nef-protein eller derivat derav koblet til et HIV-Tat-protein eller derivat derav og en fusjonspartner. Oppfinnelsen tilveiebringer videre en nukleinsyre som koder for et slikt protein og en vertscelle, slik som Pichia Pastoris, transformert med den før nevnte nukleinsyren.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9720585.0A GB9720585D0 (en) | 1997-09-26 | 1997-09-26 | Vaccine |
| PCT/EP1998/006040 WO1999016884A1 (en) | 1997-09-26 | 1998-09-17 | Fusion proteins comprising hiv-1 tat and/or nef proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076467L true NO20076467L (no) | 2000-05-18 |
Family
ID=10819735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001508A NO328824B1 (no) | 1997-09-26 | 2000-03-23 | Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. |
| NO20076467A NO20076467L (no) | 1997-09-26 | 2007-12-14 | Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001508A NO328824B1 (no) | 1997-09-26 | 2000-03-23 | Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1015596B2 (no) |
| JP (2) | JP2001518300A (no) |
| KR (1) | KR100554487B1 (no) |
| CN (1) | CN1188519C (no) |
| AR (2) | AR017147A1 (no) |
| AT (1) | ATE338128T1 (no) |
| AU (1) | AU746564B2 (no) |
| BR (1) | BR9812547A (no) |
| CA (1) | CA2305013C (no) |
| CO (1) | CO4810339A1 (no) |
| CZ (1) | CZ302878B6 (no) |
| DE (1) | DE69835756T3 (no) |
| DK (1) | DK1015596T4 (no) |
| ES (1) | ES2272012T5 (no) |
| GB (1) | GB9720585D0 (no) |
| HU (1) | HUP0004896A3 (no) |
| IL (1) | IL135102A0 (no) |
| NO (2) | NO328824B1 (no) |
| NZ (1) | NZ503482A (no) |
| PL (1) | PL195243B1 (no) |
| PT (1) | PT1015596E (no) |
| SA (1) | SA98190877B1 (no) |
| SI (1) | SI1015596T2 (no) |
| TR (1) | TR200000864T2 (no) |
| TW (1) | TW499436B (no) |
| WO (1) | WO1999016884A1 (no) |
| ZA (1) | ZA988789B (no) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9720585D0 (en) * | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
| GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| CA2363118A1 (en) * | 1999-02-25 | 2000-08-31 | Smithkline Beecham Biologicals S.A. | Immunogens comprising a peptide and a carrier derived from h.influenzae protein d |
| AU4342900A (en) * | 1999-04-12 | 2000-11-14 | Modex Therapeutiques, S.A. | Transiently immortalized cells for use in gene therapy |
| EP1198249B1 (en) * | 1999-06-29 | 2005-10-19 | GlaxoSmithKline Biologicals S.A. | Use of cpg as an adjuvant for hiv vaccine |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| EA200200724A1 (ru) * | 2000-01-31 | 2003-02-27 | Смитклайн Бичем Байолоджикалз С.А. | Вакцина для профилактической или терапевтической иммунизации против вируса иммунодефицита человека (вич) |
| US6472176B2 (en) | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| GB0110431D0 (en) * | 2001-04-27 | 2001-06-20 | Glaxosmithkline Biolog Sa | Novel compounds |
| EP1279404A1 (en) * | 2001-07-26 | 2003-01-29 | Istituto Superiore di Sanità | Use of HIV-1 tat, fragments or derivatives thereof, to target or to activate antigen-presenting cells, to deliver cargo molecules for vaccination or to treat other diseases |
| GB0118367D0 (en) * | 2001-07-27 | 2001-09-19 | Glaxosmithkline Biolog Sa | Novel use |
| EP1944043A1 (en) | 2001-11-21 | 2008-07-16 | The Trustees of the University of Pennsylvania | Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use |
| CN1578678B (zh) | 2001-11-21 | 2010-05-26 | 宾夕法尼亚州立大学托管会 | 猿猴腺病毒的核酸和氨基酸序列,含有它们的载体以及用法 |
| KR100466382B1 (ko) * | 2002-01-08 | 2005-01-14 | 주식회사 엘지생명과학 | 인간 면역 결핍 바이러스-1, -2 타입의 단백질이 융합된 재조합 콤보 단백질, 이의 생산방법, 이를 포함하는 벡터, 형질전환된 대장균 및 진단키트 |
| GB0206360D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| GB0206359D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| ES2253675T3 (es) | 2002-05-16 | 2006-06-01 | Bavarian Nordic A/S | Proteina de fusion de proteinas reguladoras/accesorias de hiv. |
| GB0225788D0 (en) | 2002-11-05 | 2002-12-11 | Glaxo Group Ltd | Vaccine |
| US20050208482A1 (en) | 2004-03-16 | 2005-09-22 | Cohen David I | Tat-based immunomodulatory compositions and methods for their discovery and use |
| TW200613554A (en) | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| GB0507003D0 (en) * | 2005-04-06 | 2005-05-11 | Molmed Spa | Therapeutic |
| JP2009511081A (ja) | 2005-10-18 | 2009-03-19 | ナショナル ジューイッシュ メディカル アンド リサーチ センター | 条件的に不死化された長期幹細胞およびそのような細胞を作製および使用する方法 |
| CA2707029A1 (en) | 2007-11-28 | 2009-08-27 | Soumitra Roy | Simian subfamily c adenoviruses sadv-40, -31, and -34 and uses thereof |
| WO2009073104A2 (en) | 2007-11-28 | 2009-06-11 | The Trustees Of The University Of Pennsylvania | Simian e adenoviruses sadv-39, -25. 2, -26, -30, -37, and -38 |
| EP2250255A2 (en) | 2008-03-04 | 2010-11-17 | The Trustees of the University of Pennsylvania | Simian adenoviruses sadv-36,-42.1, -42.2, and -44 and uses thereof |
| KR101803099B1 (ko) | 2008-05-16 | 2017-11-30 | 타이가 바이오테크놀로지스, 인코포레이티드 | 항체 및 그 제조 방법 |
| US9169462B2 (en) | 2008-07-21 | 2015-10-27 | Taiga Biotechnologies, Inc. | Methods for preparing mature erythrocytes from conditionally immortalized hematopoietic stem cells |
| JP5812861B2 (ja) | 2008-08-28 | 2015-11-17 | タイガ バイオテクノロジーズ,インク. | Mycの修飾物質、該mycの修飾物質を使用する方法、およびmycを調節する薬剤を同定する方法 |
| EP2774985B1 (en) | 2008-10-31 | 2016-12-14 | The Trustees Of The University Of Pennsylvania | Simian adenovirus SAdV-43 and uses thereof |
| DK2411043T3 (da) | 2009-03-23 | 2013-10-21 | Pin Pharma Inc | Behandling af cancer med immunostimulatorisk hiv tat derivat-polypeptider |
| CA2762203A1 (en) | 2009-05-29 | 2010-12-02 | Soumitra Roy | Simian adenovirus 41 and uses thereof |
| WO2012071318A2 (en) | 2010-11-23 | 2012-05-31 | The Trustees Of The University Of Pennsylvania | Subfamily e simian adenoviruses a1321, a1325, a1295, a1309, a1316 and a1322 and uses thereof |
| EP2708561A4 (en) * | 2011-03-15 | 2014-09-24 | Univ Yonsei Iacf | BIO-PIN |
| EP2850194A4 (en) | 2012-05-18 | 2016-06-08 | Univ Pennsylvania | APE-ADENOVIRES A1302, A1320, A1331 AND A1337 OF THE FAMILY E AND USES THEREOF |
| WO2014012090A1 (en) | 2012-07-13 | 2014-01-16 | The Broad Institute, Inc. | Molecular sleds comprising a positively-charged amino acid sequence and a molecular cargo and uses thereof |
| CA2879667C (en) | 2012-07-20 | 2021-11-16 | Taiga Biotechnologies, Inc. | Enhanced reconstitution and autoreconstitution of the hematopoietic compartment comprising a myc polypeptide |
| US9365825B2 (en) | 2013-03-11 | 2016-06-14 | Taiga Biotechnologies, Inc. | Expansion of adult stem cells in vitro |
| US10272115B2 (en) | 2013-03-11 | 2019-04-30 | Taiga Biotechnologies, Inc. | Production and use of red blood cells |
| RU2695653C2 (ru) | 2013-10-04 | 2019-07-25 | Пин Фарма, Инк. | Иммуностимулирующие полипептидные производные тат вич для применения в лечении рака |
| DK3142750T3 (da) | 2014-05-13 | 2020-09-14 | Univ Pennsylvania | Sammensætninger omfattende aav, som udtrykker dobbelt-antistofkonstrukter og anvendelser deraf |
| US11207421B2 (en) | 2015-04-16 | 2021-12-28 | The Research Foundation For The State University Of New York | Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags |
| ES2865392T7 (es) * | 2015-04-16 | 2022-09-07 | The Research Foundation For The State Univ Of New York Univ At Buffalo | Nanoestructuras que comprenden conjugados de porfirina de cobalto-fosfolípido y etiquetas de polihistidina |
| WO2018102678A1 (en) | 2016-12-02 | 2018-06-07 | Taiga Biotechnologies, Inc. | Nanoparticle formulations |
| US10149898B2 (en) | 2017-08-03 | 2018-12-11 | Taiga Biotechnologies, Inc. | Methods and compositions for the treatment of melanoma |
| EP3952909A4 (en) | 2019-04-08 | 2023-06-07 | Taiga Biotechnologies, Inc. | COMPOSITIONS AND METHODS FOR CRYOPRESERVING IMMUNE CELLS |
| CA3137031A1 (en) | 2019-05-14 | 2020-11-19 | Yosef Refaeli | Compositions and methods for treating t cell exhaustion |
| WO2022232289A1 (en) | 2021-04-27 | 2022-11-03 | Generation Bio Co. | Non-viral dna vectors expressing therapeutic antibodies and uses thereof |
| WO2023177655A1 (en) | 2022-03-14 | 2023-09-21 | Generation Bio Co. | Heterologous prime boost vaccine compositions and methods of use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9003010D0 (en) * | 1990-02-09 | 1990-04-04 | Glaxo Group Ltd | Gene expression in yeast cells |
| AU681572B2 (en) * | 1991-10-21 | 1997-09-04 | Med Immune, Inc. | Bacterial expression vectors containing DNA encoding secretion signals of lipoproteins |
| JP2702285B2 (ja) * | 1992-08-21 | 1998-01-21 | バイオジェン,インコーポレイテッド | Tat由来の輸送ポリペプチド |
| DE69434469T2 (de) * | 1993-01-26 | 2006-06-14 | Univ Pennsylvania | Zusammensetzungen und verfahren zur verabreichung von genetischem material |
| EP0814834B2 (fr) * | 1995-03-08 | 2009-03-18 | Neovacs | Immunogenes denues de toxicite derivant d'une proteine de regulation retrovirale, anticorps diriges contre ces immunogenes, procede pour leur preparation et compositions pharmaceutiques les renfermant |
| GB9720585D0 (en) * | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
-
1997
- 1997-09-26 GB GBGB9720585.0A patent/GB9720585D0/en not_active Ceased
-
1998
- 1998-09-17 EP EP98952625A patent/EP1015596B2/en not_active Expired - Lifetime
- 1998-09-17 AT AT98952625T patent/ATE338128T1/de active
- 1998-09-17 DE DE69835756T patent/DE69835756T3/de not_active Expired - Lifetime
- 1998-09-17 BR BR9812547-8A patent/BR9812547A/pt not_active IP Right Cessation
- 1998-09-17 IL IL13510298A patent/IL135102A0/xx not_active IP Right Cessation
- 1998-09-17 CA CA002305013A patent/CA2305013C/en not_active Expired - Fee Related
- 1998-09-17 NZ NZ503482A patent/NZ503482A/en not_active IP Right Cessation
- 1998-09-17 DK DK98952625.6T patent/DK1015596T4/da active
- 1998-09-17 AU AU10255/99A patent/AU746564B2/en not_active Ceased
- 1998-09-17 KR KR1020007003180A patent/KR100554487B1/ko not_active Expired - Fee Related
- 1998-09-17 JP JP2000513953A patent/JP2001518300A/ja not_active Withdrawn
- 1998-09-17 PL PL98339432A patent/PL195243B1/pl not_active IP Right Cessation
- 1998-09-17 TR TR2000/00864T patent/TR200000864T2/xx unknown
- 1998-09-17 CN CNB988114321A patent/CN1188519C/zh not_active Expired - Fee Related
- 1998-09-17 WO PCT/EP1998/006040 patent/WO1999016884A1/en not_active Ceased
- 1998-09-17 SI SI9830860T patent/SI1015596T2/sl unknown
- 1998-09-17 ES ES98952625T patent/ES2272012T5/es not_active Expired - Lifetime
- 1998-09-17 PT PT98952625T patent/PT1015596E/pt unknown
- 1998-09-17 CZ CZ20001091A patent/CZ302878B6/cs not_active IP Right Cessation
- 1998-09-17 HU HU0004896A patent/HUP0004896A3/hu unknown
- 1998-09-24 AR ARP980104779A patent/AR017147A1/es active IP Right Grant
- 1998-09-25 CO CO98056054A patent/CO4810339A1/es unknown
- 1998-09-25 ZA ZA9808789A patent/ZA988789B/xx unknown
- 1998-10-22 TW TW087117493A patent/TW499436B/zh not_active IP Right Cessation
- 1998-12-15 SA SA98190877A patent/SA98190877B1/ar unknown
-
2000
- 2000-03-23 NO NO20001508A patent/NO328824B1/no not_active IP Right Cessation
-
2007
- 2007-12-14 NO NO20076467A patent/NO20076467L/no unknown
-
2009
- 2009-06-30 JP JP2009155916A patent/JP2009213492A/ja active Pending
-
2011
- 2011-02-28 AR ARP110100606A patent/AR080331A2/es not_active Application Discontinuation
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