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NO20071107L - 1,1,2,2-tetra(hetero)aryletaner eller 1,1,2-tri(hetero)aryl-2-heterosyklyletaner som kaliumkanalinhibitorer - Google Patents

1,1,2,2-tetra(hetero)aryletaner eller 1,1,2-tri(hetero)aryl-2-heterosyklyletaner som kaliumkanalinhibitorer

Info

Publication number
NO20071107L
NO20071107L NO20071107A NO20071107A NO20071107L NO 20071107 L NO20071107 L NO 20071107L NO 20071107 A NO20071107 A NO 20071107A NO 20071107 A NO20071107 A NO 20071107A NO 20071107 L NO20071107 L NO 20071107L
Authority
NO
Norway
Prior art keywords
hetero
heterocyclylethanes
arylethanes
tetra
tri
Prior art date
Application number
NO20071107A
Other languages
English (en)
Inventor
Mark T Bilodeau
Zhicai Wu
John Hartnett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO20071107L publication Critical patent/NO20071107L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Foreliggende oppfinnelse angår forbindelser som har strukturen av formel (I) som er anvendbare som kaliumkanalinhibitorer for behandling av hjertearytmier.
NO20071107A 2004-07-29 2007-02-27 1,1,2,2-tetra(hetero)aryletaner eller 1,1,2-tri(hetero)aryl-2-heterosyklyletaner som kaliumkanalinhibitorer NO20071107L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59218104P 2004-07-29 2004-07-29
PCT/US2005/026334 WO2006028590A1 (en) 2004-07-29 2005-07-25 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri (hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors

Publications (1)

Publication Number Publication Date
NO20071107L true NO20071107L (no) 2007-04-19

Family

ID=35613661

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071107A NO20071107L (no) 2004-07-29 2007-02-27 1,1,2,2-tetra(hetero)aryletaner eller 1,1,2-tri(hetero)aryl-2-heterosyklyletaner som kaliumkanalinhibitorer

Country Status (15)

Country Link
KR (1) KR20070043985A (no)
AR (1) AR049847A1 (no)
BR (1) BRPI0513793A (no)
CR (1) CR8876A (no)
EC (1) ECSP077208A (no)
IL (1) IL180846A0 (no)
MA (1) MA28980B1 (no)
MX (1) MX2007001188A (no)
NO (1) NO20071107L (no)
PE (1) PE20060382A1 (no)
RU (1) RU2344134C2 (no)
TW (1) TW200607493A (no)
UA (1) UA88018C2 (no)
WO (1) WO2006028590A1 (no)
ZA (1) ZA200700477B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012520829A (ja) * 2009-03-18 2012-09-10 メディキュア・インターナショナル・インコーポレーテッド チロフィバンの経皮用医薬製剤および投与
ES2675314T3 (es) 2012-06-11 2018-07-10 Bristol-Myers Squibb Company Profármacos de ácido fosforamídico de 5-[5-fenil-4-(piridin-2-ilmetilamino) quinazolin-2-il] piridin-3-sulfonamida

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2140865B2 (de) * 1971-08-14 1979-10-11 Bayer Ag, 5090 Leverkusen 1 -Imidazolyl-methanphosphonsäureester, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE19951701A1 (de) * 1999-10-27 2001-05-03 Aventis Pharma Gmbh Verwendung von 2-Imidazolyl-substituierten Carbinolen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten
EP1911740B1 (en) * 2002-01-04 2013-02-27 NeuroSearch A/S Potassium channel modulators

Also Published As

Publication number Publication date
AR049847A1 (es) 2006-09-06
ZA200700477B (en) 2009-08-26
TW200607493A (en) 2006-03-01
UA88018C2 (ru) 2009-09-10
CR8876A (es) 2007-08-28
PE20060382A1 (es) 2006-05-15
KR20070043985A (ko) 2007-04-26
BRPI0513793A (pt) 2008-05-13
RU2344134C2 (ru) 2009-01-20
WO2006028590A1 (en) 2006-03-16
ECSP077208A (es) 2007-02-28
RU2007107408A (ru) 2008-09-10
MX2007001188A (es) 2007-03-21
IL180846A0 (en) 2007-06-03
MA28980B1 (fr) 2007-11-01

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Legal Events

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