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NO20064852L - Azaindoler som er nyttige som inhibitorer av jak og andre proteinkinaser - Google Patents

Azaindoler som er nyttige som inhibitorer av jak og andre proteinkinaser

Info

Publication number
NO20064852L
NO20064852L NO20064852A NO20064852A NO20064852L NO 20064852 L NO20064852 L NO 20064852L NO 20064852 A NO20064852 A NO 20064852A NO 20064852 A NO20064852 A NO 20064852A NO 20064852 L NO20064852 L NO 20064852L
Authority
NO
Norway
Prior art keywords
inhibitors
protein kinases
yak
azaindoles useful
azaindoles
Prior art date
Application number
NO20064852A
Other languages
English (en)
Other versions
NO340403B1 (no
Inventor
David Jeffrey Lauffer
Francesco Gerald Salituro
Luc J Farmer
Jeremy Green
Randy Bethiel
Edmund Harrington
John Court
Jon Come
Alex Aronow
Hayley Binch
Dean Boyall
Jean-Damine Charrier
Simon Eveitt
Damien Fraysse
Michael Mortimore
Francoise Pierard
Daniela Robinson
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20064852(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20064852L publication Critical patent/NO20064852L/no
Publication of NO340403B1 publication Critical patent/NO340403B1/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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Abstract

Foreliggende oppfinnelse vedrører inhibitorer av proteinkinaser. Oppfinnelsen tilveiebringer også farmasøytiske sammensetninger omfattende forbindelsene ifølge oppfinnelsen og metoder for å anvende sammensetningene i behandlingen av forskjellige forstyrrelser.
NO20064852A 2004-03-30 2006-10-24 Azaindoler som er nyttige som inhibitorer av jak og andre proteinkinaser NO340403B1 (no)

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