NO20055367L - Kombinasjoner som innbefatter paroksetin og 2-(S)-4-fluor-2-metyl-fenyl)-piperazin-1-karboksylsyer (1-(R)-(3,5-bis-trifluor-2-metyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst - Google Patents
Kombinasjoner som innbefatter paroksetin og 2-(S)-4-fluor-2-metyl-fenyl)-piperazin-1-karboksylsyer (1-(R)-(3,5-bis-trifluor-2-metyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angstInfo
- Publication number
- NO20055367L NO20055367L NO20055367A NO20055367A NO20055367L NO 20055367 L NO20055367 L NO 20055367L NO 20055367 A NO20055367 A NO 20055367A NO 20055367 A NO20055367 A NO 20055367A NO 20055367 L NO20055367 L NO 20055367L
- Authority
- NO
- Norway
- Prior art keywords
- phenyl
- methyl
- combinations
- anxiety
- piperazine
- Prior art date
Links
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title abstract 2
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 208000020401 Depressive disease Diseases 0.000 title abstract 2
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title abstract 2
- 230000036506 anxiety Effects 0.000 title abstract 2
- 229960002296 paroxetine Drugs 0.000 title abstract 2
- MGJXBDMLVWIYOQ-UHFFFAOYSA-N methylazanide Chemical compound [NH-]C MGJXBDMLVWIYOQ-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- -1 4-fluoro-2-methylphenyl Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Forehggende oppfirmelse angår terapeutiske kombinasjoner som irmbefatter paroksetin eller fysiologisk akseptable salter eller solvater derav og 2-(S)-(4-fluor-2-metyIfenyl)-piperazin-l-karboksylsyre [1-(R)- (3,5-bis-trifluormetyl-fenyl)-etyl]-metyl-amid eller fysiologisk akseptable salter eller solvater derav, farmasøytiske sammensetninger som irmeholder nevnte kombinasjoner og deres anvendelse ved behandling av depresjon og/eller angst.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0308968.7A GB0308968D0 (en) | 2003-04-17 | 2003-04-17 | Medicaments |
| PCT/EP2004/004126 WO2004091624A1 (en) | 2003-04-17 | 2004-04-16 | Combinations comprising paroxetine and 2- (s) - (4-fluoro-2-methyl-phenyl) -piperazine-1-carboxylic acid [1- (r)- (3,5-bis-trifluoro-2-methyl-phenyl) -ethyl]-methyl amide for treatment of depression and/or anxiety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20055367L true NO20055367L (no) | 2005-11-14 |
Family
ID=9956996
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20055368A NO20055368L (no) | 2003-04-17 | 2005-11-14 | Kombinasjoner av paroksetin og 4-(S)-(4-acetyl-piperazin-1-yl-)-2-(R)-(4-trifluor-2-metyl-fenyl)-piperidin-1-karboksylsyre{1\\[1-(R)-3,5-bis-trifluormetyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst |
| NO20055367A NO20055367L (no) | 2003-04-17 | 2005-11-14 | Kombinasjoner som innbefatter paroksetin og 2-(S)-4-fluor-2-metyl-fenyl)-piperazin-1-karboksylsyer (1-(R)-(3,5-bis-trifluor-2-metyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20055368A NO20055368L (no) | 2003-04-17 | 2005-11-14 | Kombinasjoner av paroksetin og 4-(S)-(4-acetyl-piperazin-1-yl-)-2-(R)-(4-trifluor-2-metyl-fenyl)-piperidin-1-karboksylsyre{1\\[1-(R)-3,5-bis-trifluormetyl-fenyl)-etyl]metylamid for behandling av depresjon og/eller angst |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US20060241143A1 (no) |
| EP (4) | EP1615641A1 (no) |
| JP (4) | JP2006523649A (no) |
| KR (2) | KR20060003876A (no) |
| CN (2) | CN1809355A (no) |
| AU (2) | AU2004229179A1 (no) |
| BR (2) | BRPI0409377A (no) |
| CA (2) | CA2522313A1 (no) |
| CO (1) | CO5700753A2 (no) |
| GB (1) | GB0308968D0 (no) |
| IS (2) | IS8128A (no) |
| MA (2) | MA27731A1 (no) |
| MX (2) | MXPA05011064A (no) |
| NO (2) | NO20055368L (no) |
| PL (2) | PL377858A1 (no) |
| RU (2) | RU2005135647A (no) |
| WO (4) | WO2004091616A1 (no) |
| ZA (2) | ZA200508068B (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0203020D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| GB0403149D0 (en) * | 2004-02-12 | 2004-03-17 | Glaxo Group Ltd | Medicament |
| GB0409098D0 (en) * | 2004-04-23 | 2004-05-26 | Glaxo Group Ltd | Medicament |
| GB0426942D0 (en) * | 2004-12-08 | 2005-01-12 | Glaxo Group Ltd | Medicament |
| WO2007012968A2 (en) * | 2005-07-29 | 2007-02-01 | Aurobindo Pharma Ltd | Stable dosage form of an antidepressant |
| GB0621229D0 (en) * | 2006-10-20 | 2006-12-06 | Glaxo Group Ltd | Novel use |
| WO2008090114A1 (en) | 2007-01-24 | 2008-07-31 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| WO2012175434A1 (en) * | 2011-06-20 | 2012-12-27 | Glaxo Group Limited | Pharmaceutical formulations comprising vestipitant |
| CN103446066B (zh) * | 2013-09-16 | 2014-12-24 | 南通丝乡丝绸有限公司 | 帕罗西汀冻干粉针及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL111002A (en) * | 1993-09-22 | 1998-09-24 | Glaxo Group Ltd | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
| US6117855A (en) * | 1996-10-07 | 2000-09-12 | Merck Sharp & Dohme Ltd. | Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent |
| WO1998047514A1 (en) * | 1997-04-24 | 1998-10-29 | Merck Sharp & Dohme Limited | Use of an nk-1 receptor antagonist and an ssri for treating obesity |
| GB9923748D0 (en) * | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
| IL150033A0 (en) * | 1999-12-17 | 2002-12-01 | Schering Corp | Selective neurokinin antagonists |
| US6436928B1 (en) * | 1999-12-17 | 2002-08-20 | Schering Corporation | Selective neurokinin antagonists |
| GT200100147A (es) * | 2000-07-31 | 2002-06-25 | Derivados de imidazol | |
| GB0025354D0 (en) * | 2000-10-17 | 2000-11-29 | Glaxo Group Ltd | Chemical compounds |
| GB0119797D0 (en) * | 2001-08-14 | 2001-10-03 | Glaxo Group Ltd | Chemical compounds |
| ES2291538T3 (es) * | 2001-11-13 | 2008-03-01 | Schering Corporation | Antagonistas de nk1. |
| GB0203020D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
-
2003
- 2003-04-17 GB GBGB0308968.7A patent/GB0308968D0/en not_active Ceased
-
2004
- 2004-04-16 CA CA002522313A patent/CA2522313A1/en not_active Abandoned
- 2004-04-16 EP EP04739085A patent/EP1615641A1/en not_active Withdrawn
- 2004-04-16 BR BRPI0409377-1A patent/BRPI0409377A/pt not_active Application Discontinuation
- 2004-04-16 WO PCT/EP2004/004122 patent/WO2004091616A1/en not_active Ceased
- 2004-04-16 KR KR1020057019521A patent/KR20060003876A/ko not_active Withdrawn
- 2004-04-16 US US10/552,870 patent/US20060241143A1/en not_active Abandoned
- 2004-04-16 EP EP04739086A patent/EP1615642A1/en not_active Withdrawn
- 2004-04-16 MX MXPA05011064A patent/MXPA05011064A/es unknown
- 2004-04-16 US US10/552,869 patent/US20060241124A1/en not_active Abandoned
- 2004-04-16 RU RU2005135647/15A patent/RU2005135647A/ru not_active Application Discontinuation
- 2004-04-16 PL PL377858A patent/PL377858A1/pl not_active Application Discontinuation
- 2004-04-16 MX MXPA05011063A patent/MXPA05011063A/es unknown
- 2004-04-16 AU AU2004229179A patent/AU2004229179A1/en not_active Abandoned
- 2004-04-16 KR KR1020057019520A patent/KR20060003875A/ko not_active Withdrawn
- 2004-04-16 JP JP2006505185A patent/JP2006523649A/ja active Pending
- 2004-04-16 CA CA002522311A patent/CA2522311A1/en not_active Abandoned
- 2004-04-16 WO PCT/EP2004/004124 patent/WO2004091617A1/en not_active Ceased
- 2004-04-16 CN CNA2004800171620A patent/CN1809355A/zh active Pending
- 2004-04-16 JP JP2006505187A patent/JP2006523651A/ja active Pending
- 2004-04-16 AU AU2004229181A patent/AU2004229181A1/en not_active Abandoned
- 2004-04-16 EP EP04727895A patent/EP1613325A1/en not_active Withdrawn
- 2004-04-16 BR BRPI0409379-8A patent/BRPI0409379A/pt not_active Application Discontinuation
- 2004-04-16 JP JP2006505188A patent/JP2006523652A/ja active Pending
- 2004-04-16 WO PCT/EP2004/004126 patent/WO2004091624A1/en not_active Ceased
- 2004-04-16 WO PCT/EP2004/004121 patent/WO2004091615A1/en not_active Ceased
- 2004-04-16 JP JP2006505186A patent/JP2006523650A/ja active Pending
- 2004-04-16 RU RU2005135649/15A patent/RU2005135649A/ru not_active Application Discontinuation
- 2004-04-16 US US10/552,871 patent/US20060217395A1/en not_active Abandoned
- 2004-04-16 EP EP04727896A patent/EP1653956A1/en not_active Withdrawn
- 2004-04-16 US US10/552,982 patent/US20060287325A1/en not_active Abandoned
- 2004-04-16 CN CNA2004800172252A patent/CN1809359A/zh active Pending
- 2004-04-16 PL PL377857A patent/PL377857A1/pl not_active Application Discontinuation
-
2005
- 2005-10-06 ZA ZA200508068A patent/ZA200508068B/en unknown
- 2005-10-06 ZA ZA200508067A patent/ZA200508067B/en unknown
- 2005-10-14 CO CO05105292A patent/CO5700753A2/es not_active Application Discontinuation
- 2005-10-19 MA MA28562A patent/MA27731A1/fr unknown
- 2005-10-19 MA MA28561A patent/MA27730A1/fr unknown
- 2005-11-14 NO NO20055368A patent/NO20055368L/no not_active Application Discontinuation
- 2005-11-14 NO NO20055367A patent/NO20055367L/no not_active Application Discontinuation
- 2005-11-15 IS IS8128A patent/IS8128A/is unknown
- 2005-11-15 IS IS8129A patent/IS8129A/is unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |