DE60322064D1 - 4,4' -dithiobis- (3-aminobutane-1-sulfonate)-derivate und sie enthaltende zusammensetzungen - Google Patents
4,4' -dithiobis- (3-aminobutane-1-sulfonate)-derivate und sie enthaltende zusammensetzungenInfo
- Publication number
- DE60322064D1 DE60322064D1 DE60322064T DE60322064T DE60322064D1 DE 60322064 D1 DE60322064 D1 DE 60322064D1 DE 60322064 T DE60322064 T DE 60322064T DE 60322064 T DE60322064 T DE 60322064T DE 60322064 D1 DE60322064 D1 DE 60322064D1
- Authority
- DE
- Germany
- Prior art keywords
- aminobutane
- dithiobis
- sulphonate
- derivatives
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HJPXZXVKLGEMGP-UHFFFAOYSA-N 3-amino-4-[(2-amino-4-sulfobutyl)disulfanyl]butane-1-sulfonic acid Chemical class OS(=O)(=O)CCC(N)CSSCC(N)CCS(O)(=O)=O HJPXZXVKLGEMGP-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0208977A FR2842522B1 (fr) | 2002-07-16 | 2002-07-16 | Derives de 4,4'-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositons les contenant |
| FR0303425A FR2852597A1 (fr) | 2003-03-20 | 2003-03-20 | Derives de 4,4'-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositions les contenant |
| PCT/FR2003/002242 WO2004007441A2 (fr) | 2002-07-16 | 2003-07-16 | Derives de 4,4' -dithiobis- (3-aminobutane-1-sulfonates) nouveaux et compositions les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60322064D1 true DE60322064D1 (de) | 2008-08-21 |
Family
ID=30117028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60322064T Expired - Lifetime DE60322064D1 (de) | 2002-07-16 | 2003-07-16 | 4,4' -dithiobis- (3-aminobutane-1-sulfonate)-derivate und sie enthaltende zusammensetzungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7235687B2 (de) |
| EP (1) | EP1525188B1 (de) |
| AT (1) | ATE400552T1 (de) |
| AU (1) | AU2003271811A1 (de) |
| CY (1) | CY1109013T1 (de) |
| DE (1) | DE60322064D1 (de) |
| DK (1) | DK1525188T3 (de) |
| ES (1) | ES2309336T3 (de) |
| PT (1) | PT1525188E (de) |
| SI (1) | SI1525188T1 (de) |
| WO (1) | WO2004007441A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007012782A (es) | 2005-04-15 | 2008-03-14 | Epigenomics Ag | Metodos y acidos nucleicos para analisis de trastornos proliferativos celulares. |
| FR2931151A1 (fr) * | 2008-05-13 | 2009-11-20 | Pharmaleads Soc Par Actions Si | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
| EP2322514A1 (de) * | 2009-11-11 | 2011-05-18 | Bayer Schering Pharma Aktiengesellschaft | Homoglutaminsäure und Glutaminsäurederivate |
| EP2439192A1 (de) * | 2010-10-07 | 2012-04-11 | Quantum Genomics | Verfahren zur Herstellung von (3S,3S') 4,4'-disulfandiylbis (3-aminobutan 1-sulfonsäure) |
| SI2793878T1 (sl) * | 2011-12-21 | 2017-07-31 | Quantum Genomics Tour Montparnasse | Kombinacija (3s,3s')4,4'-disulfandiilbis (3-aminobutan 1-sulfonska kislina) in drugo antihipertenzivno sredstvo |
| EP2722327A1 (de) * | 2012-10-22 | 2014-04-23 | Quantum Genomics | Kristalline Phase von (3S,3S') 4,4'-disulfandiylbis (3-Aminobutan 1-Sulfonsäure) mit L-Lysin |
| CA2964474A1 (en) * | 2014-10-17 | 2016-04-21 | University Of Florida Research Foundation | Novel small molecule anticancer agents |
| US10501426B1 (en) | 2019-01-11 | 2019-12-10 | King Saud University | Synthesis of thiazole derivative as anticancer and anti-antibiotics resistant bacteria agent |
| CN110845347B (zh) * | 2019-11-21 | 2021-10-15 | 利尔化学股份有限公司 | 一种氯代高丝氨酸烷基酯的制备方法 |
| TW202207917A (zh) | 2020-05-06 | 2022-03-01 | 法商量子基因科技有限公司 | 包含腦胺肽酶抑制劑、利尿劑及全身性腎素－血管收縮素系統阻斷劑之醫藥組合物 |
| WO2022225712A1 (en) | 2021-04-22 | 2022-10-27 | Teva Pharmaceuticals International Gmbh | Solid state forms of firibastat and processes for preparation thereof |
| CN115448833B (zh) * | 2022-08-25 | 2024-07-05 | 湖北泰盛化工有限公司 | 一种多官能团脂肪族伯醇衍生物的羟基直接氯代方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2773712B1 (fr) | 1998-01-16 | 2000-06-02 | Inst Nat Sante Rech Med | Composition pharmaceutique comprenant au moins un inhibiteur de l'aminopeptidase a |
-
2003
- 2003-07-16 SI SI200331379T patent/SI1525188T1/sl unknown
- 2003-07-16 EP EP03753648A patent/EP1525188B1/de not_active Expired - Lifetime
- 2003-07-16 AU AU2003271811A patent/AU2003271811A1/en not_active Abandoned
- 2003-07-16 ES ES03753648T patent/ES2309336T3/es not_active Expired - Lifetime
- 2003-07-16 AT AT03753648T patent/ATE400552T1/de active
- 2003-07-16 DE DE60322064T patent/DE60322064D1/de not_active Expired - Lifetime
- 2003-07-16 DK DK03753648T patent/DK1525188T3/da active
- 2003-07-16 WO PCT/FR2003/002242 patent/WO2004007441A2/fr not_active Ceased
- 2003-07-16 US US10/521,171 patent/US7235687B2/en not_active Expired - Lifetime
- 2003-07-16 PT PT03753648T patent/PT1525188E/pt unknown
-
2008
- 2008-10-07 CY CY20081101109T patent/CY1109013T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003271811A8 (en) | 2004-02-02 |
| AU2003271811A1 (en) | 2004-02-02 |
| WO2004007441A2 (fr) | 2004-01-22 |
| US7235687B2 (en) | 2007-06-26 |
| EP1525188A2 (de) | 2005-04-27 |
| PT1525188E (pt) | 2008-10-16 |
| EP1525188B1 (de) | 2008-07-09 |
| ATE400552T1 (de) | 2008-07-15 |
| DK1525188T3 (da) | 2008-11-17 |
| ES2309336T3 (es) | 2008-12-16 |
| WO2004007441A3 (fr) | 2004-04-08 |
| US20060135602A1 (en) | 2006-06-22 |
| SI1525188T1 (sl) | 2008-12-31 |
| CY1109013T1 (el) | 2014-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, , FR Owner name: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERC, FR Owner name: UNIVERSITE PARIS DESCARTES, PARIS, FR |