NO20026168L - Heksanderivater som har opioid reseptor affinitet - Google Patents

Heksanderivater som har opioid reseptor affinitet

Info

Publication number: NO20026168L
Authority: NO; Norway
Prior art keywords: opioid receptor; receptor affinity; hexane derivatives; hexane; derivatives
Prior art date: 2000-06-23

Application number

NO20026168A

Other languages

English (en)

Norwegian (no)

Other versions

NO20026168D0 (no

Inventor

Bernard Joseph

Douglas James Critcher

Ashley FENWICK

David Morris Gethin

Stephen Paul Gibson

Graham Lunn

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-23

Filing date

2002-12-20

Publication date

2003-02-18

2002-12-20 Application filed by Pfizer filed Critical Pfizer

2002-12-20 Publication of NO20026168D0 publication Critical patent/NO20026168D0/no

2003-02-18 Publication of NO20026168L publication Critical patent/NO20026168L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Addiction (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Otolaryngology (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Nutrition Science (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

NO20026168A 2000-06-23 2002-12-20 Heksanderivater som har opioid reseptor affinitet NO20026168L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0015562.2A GB0015562D0 (en)	2000-06-23	2000-06-23	Heterocycles
PCT/IB2001/001035 WO2001098267A1 (fr)	2000-06-23	2001-06-07	Derives 3-azabicyclo[3.1.0] hexane ayant une affinite pour le recepteur opioide

Publications (2)

Publication Number	Publication Date
NO20026168D0 NO20026168D0 (no)	2002-12-20
NO20026168L true NO20026168L (no)	2003-02-18

Family

ID=9894368

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20026168A NO20026168L (no)	2000-06-23	2002-12-20	Heksanderivater som har opioid reseptor affinitet

Country Status (34)

Country	Link
EP (1)	EP1292574A1 (fr)
JP (1)	JP2004512263A (fr)
KR (1)	KR20040002386A (fr)
CN (1)	CN1639121A (fr)
AP (1)	AP2002002698A0 (fr)
AR (1)	AR028969A1 (fr)
AU (1)	AU781837B2 (fr)
BG (1)	BG107329A (fr)
BR (1)	BR0111867A (fr)
CA (1)	CA2412188A1 (fr)
CZ (1)	CZ20023967A3 (fr)
DO (1)	DOP2001000187A (fr)
DZ (1)	DZ3368A1 (fr)
EA (1)	EA005117B1 (fr)
GB (1)	GB0015562D0 (fr)
HR (1)	HRP20020998A2 (fr)
HU (1)	HUP0301228A3 (fr)
IL (1)	IL153427A0 (fr)
IS (1)	IS6637A (fr)
MA (1)	MA26915A1 (fr)
MX (1)	MXPA02012878A (fr)
NO (1)	NO20026168L (fr)
NZ (1)	NZ523141A (fr)
OA (1)	OA12293A (fr)
PA (1)	PA8519401A1 (fr)
PE (1)	PE20020253A1 (fr)
PL (1)	PL365956A1 (fr)
SK (1)	SK17172002A3 (fr)
TN (1)	TNSN01094A1 (fr)
UA (1)	UA73176C2 (fr)
UY (1)	UY26787A1 (fr)
WO (1)	WO2001098267A1 (fr)
YU (1)	YU91802A (fr)
ZA (1)	ZA200210278B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR0213464A (pt) *	2001-10-22	2004-11-09	Pfizer Prod Inc	Derivados de 3-azabiciclo[3.1.0]hexano como antagonistas receptores de opióide
DK1505974T3 (da) *	2002-05-17	2009-08-17	Tioga Pharmaceuticals Inc	Anvendelse af forbindelser, der er effektive som selektive opiatreceptormodulatorer
DE10259245A1 (de)	2002-12-17	2004-07-01	Merck Patent Gmbh	Derivate des Asimadolins mit kovalent gebundenen Säuren
CN1946714B (zh) *	2004-02-23	2011-06-15	葛兰素集团有限公司	用作多巴胺d3受体调节剂的氮杂二环(3.1.0)己烷衍生物
GB0507680D0 (en)	2005-04-15	2005-05-25	Glaxo Group Ltd	Compounds
US7807698B2 (en)	2005-06-14	2010-10-05	Glaxo Group Limited	Azabicyclo[3.1.0]hexane derivatives as modulators of the dopamine D3 receptor
WO2007113258A1 (fr) *	2006-04-03	2007-10-11	Glaxo Group Limited	Dérivés d'azabicyclo [3. 1. o] hexane utilisés comme modulateurs des récepteurs de la dopamine d3
ES2393815T3 (es)	2007-03-30	2012-12-28	Tioga Pharmaceuticals, Inc.	Agonistas opioides kappa para el tratamiento de síndrome del intestino irritable con diarrea predominante y alternante
TWI423801B (zh) *	2007-08-27	2014-01-21	Theravance Inc	作為μ類鴉片受體拮抗劑之８－氮雜雙環〔３．２．１〕辛基－２－羥基苯甲醯胺化合物
JP5736040B2 (ja)	2010-06-11	2015-06-17	ローズテクノロジーズ	Ｎ−アリル化合物の調製のための遷移金属触媒プロセスおよびその使用
BR112013007566A2 (pt)	2010-09-28	2016-08-02	Panacea Biotec Ltd	novos compostos bicíclicos
WO2015076310A1 (fr) *	2013-11-20	2015-05-28	株式会社三和化学研究所	Nouveau dérivé 3-azabicyclo[3.1.0]hexane et son utilisation à des fins médicales
MX388953B (es)	2015-05-20	2025-03-20	Ube Industries	Cristal de sal de derivado de 3-azabiciclo[3.1.0]hexano novedoso y usos medicionales del mismo.
WO2018152286A1 (fr)	2017-02-17	2018-08-23	Trevena, Inc.	Composés modulateurs du récepteur des opioïdes delta contenant des hétérocycles aza à 7 chaînons, et leurs procédés de préparation et d'utilisation
KR20190129867A (ko) *	2017-02-17	2019-11-20	트레베나, 인코포레이티드.	5-원 아자-헤테로고리 함유 델타-오피오이드 수용체 조절 화합물, 및 그의 사용 및 제조 방법
KR20190120212A (ko)	2017-03-02	2019-10-23	가부시키가이샤산와카가쿠켄큐쇼	알코올 사용 장해의 치료약
CN108250088B (zh) *	2018-01-04	2020-10-30	四川之江高新材料股份有限公司	N，n，n′-三甲基-n′-羟乙基双氨基乙基醚的制备方法
CN115825305B (zh) *	2022-10-21	2024-09-20	昆明理工大学	一种分子印迹固相微萃取纤维及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3065230A (en) *	1959-03-16	1962-11-20	Burroughs Wellcome Co	Azabicyclohexanes and method of preparing them
NZ224236A (en) *	1987-04-16	1990-08-28	Lilly Co Eli	Trans 3,4 pyridine derivatives and pharmaceutical compositions
US5159081A (en) *	1991-03-29	1992-10-27	Eli Lilly And Company	Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
DE4341403A1 (de) *	1993-12-04	1995-06-08	Basf Ag	N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
TWI244481B (en) *	1998-12-23	2005-12-01	Pfizer	3-azabicyclo[3.1.0]hexane derivatives useful in therapy
PE20001420A1 (es) *	1998-12-23	2000-12-18	Pfizer	Moduladores de ccr5

2000
- 2000-06-23 GB GBGB0015562.2A patent/GB0015562D0/en not_active Ceased
2001
- 2001-06-06 DO DO2001000187A patent/DOP2001000187A/es unknown
- 2001-06-07 BR BR0111867-6A patent/BR0111867A/pt not_active IP Right Cessation
- 2001-06-07 HU HU0301228A patent/HUP0301228A3/hu unknown
- 2001-06-07 AU AU62591/01A patent/AU781837B2/en not_active Ceased
- 2001-06-07 JP JP2002504223A patent/JP2004512263A/ja not_active Withdrawn
- 2001-06-07 PL PL01365956A patent/PL365956A1/xx not_active Application Discontinuation
- 2001-06-07 CN CNA018116086A patent/CN1639121A/zh active Pending
- 2001-06-07 HR HR20020998A patent/HRP20020998A2/hr not_active Application Discontinuation
- 2001-06-07 KR KR1020027017503A patent/KR20040002386A/ko not_active Ceased
- 2001-06-07 CA CA002412188A patent/CA2412188A1/fr not_active Abandoned
- 2001-06-07 EP EP01936728A patent/EP1292574A1/fr not_active Withdrawn
- 2001-06-07 CZ CZ20023967A patent/CZ20023967A3/cs unknown
- 2001-06-07 IL IL15342701A patent/IL153427A0/xx unknown
- 2001-06-07 YU YU91802A patent/YU91802A/sh unknown
- 2001-06-07 WO PCT/IB2001/001035 patent/WO2001098267A1/fr not_active Ceased
- 2001-06-07 OA OA1200200386A patent/OA12293A/en unknown
- 2001-06-07 AP APAP/P/2002/002698A patent/AP2002002698A0/en unknown
- 2001-06-07 NZ NZ523141A patent/NZ523141A/en unknown
- 2001-06-07 SK SK1717-2002A patent/SK17172002A3/sk unknown
- 2001-06-07 EA EA200201269A patent/EA005117B1/ru not_active IP Right Cessation
- 2001-06-07 DZ DZ013368A patent/DZ3368A1/fr active
- 2001-06-07 MX MXPA02012878A patent/MXPA02012878A/es unknown
- 2001-06-12 PA PA20018519401A patent/PA8519401A1/es unknown
- 2001-06-21 UY UY26787A patent/UY26787A1/es not_active Application Discontinuation
- 2001-06-21 PE PE2001000604A patent/PE20020253A1/es not_active Application Discontinuation
- 2001-06-21 AR ARP010102957A patent/AR028969A1/es unknown
- 2001-06-22 TN TNTNSN01094A patent/TNSN01094A1/fr unknown
- 2001-07-06 UA UA20021210406A patent/UA73176C2/uk unknown
2002
- 2002-11-28 IS IS6637A patent/IS6637A/is unknown
- 2002-11-28 BG BG107329A patent/BG107329A/xx unknown
- 2002-12-16 MA MA26955A patent/MA26915A1/fr unknown
- 2002-12-19 ZA ZA200210278A patent/ZA200210278B/xx unknown
- 2002-12-20 NO NO20026168A patent/NO20026168L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0301228A2 (hu)	2003-08-28
PL365956A1 (en)	2005-01-24
BG107329A (en)	2003-07-31
UY26787A1 (es)	2002-01-31
CN1639121A (zh)	2005-07-13
JP2004512263A (ja)	2004-04-22
PA8519401A1 (es)	2002-12-30
MA26915A1 (fr)	2004-12-20
PE20020253A1 (es)	2002-04-08
BR0111867A (pt)	2003-07-01
AR028969A1 (es)	2003-05-28
TNSN01094A1 (fr)	2005-11-10
WO2001098267A1 (fr)	2001-12-27
EP1292574A1 (fr)	2003-03-19
HRP20020998A2 (en)	2004-02-29
YU91802A (sh)	2006-05-25
NO20026168D0 (no)	2002-12-20
MXPA02012878A (es)	2003-05-14
DOP2001000187A (es)	2002-03-30
OA12293A (en)	2004-03-18
DZ3368A1 (fr)	2001-12-27
IS6637A (is)	2002-11-28
ZA200210278B (en)	2003-12-19
UA73176C2 (en)	2005-06-15
AU781837B2 (en)	2005-06-16
NZ523141A (en)	2005-06-24
AU6259101A (en)	2002-01-02
WO2001098267A8 (fr)	2003-02-27
IL153427A0 (en)	2003-07-06
GB0015562D0 (en)	2000-08-16
EA200201269A1 (ru)	2003-06-26
KR20040002386A (ko)	2004-01-07
AP2002002698A0 (en)	2002-12-31
CZ20023967A3 (cs)	2004-02-18
SK17172002A3 (sk)	2004-09-08
CA2412188A1 (fr)	2001-12-27
HUP0301228A3 (en)	2005-08-29
EA005117B1 (ru)	2004-10-28

Publication	Publication Date	Title
NO20026168L (no)	2003-02-18	Heksanderivater som har opioid reseptor affinitet
DE60140155D1 (de)	2009-11-26	Ortsabhängige Dienstebereitstellung
DK1414440T3 (da)	2007-05-21	N-phenylpyrrolguanidinderivater som melanocortinreceptorligander
DE60227072D1 (de)	2008-07-24	Sitz
DE60218849D1 (de)	2007-04-26	Kopfstützenanordnung
DE50106084D1 (de)	2005-06-09	Kopfstütze
DE10196653T1 (de)	2003-08-07	Kopfstütze
DE50115672D1 (de)	2010-12-02	Halterung
NO20042955L (no)	2004-07-12	Substituerte fenylaftalener som estrogene midler
DK1596887T3 (da)	2022-06-20	Polymer-Faktor VIII-konjugat
DE60231490D1 (de)	2009-04-23	Verstellbarer sitz
NO20032920D0 (no)	2003-06-25	Tynnere for inverterbare emulsjoner
DK1446379T3 (da)	2009-07-27	Arylanilin-beta2-adrenergiske receptoragonister
FI20002173L (fi)	2002-04-03	Mikromekaaninen rakenne
ATE450505T1 (de)	2009-12-15	Cb 1 rezeptor inversagonisten
DK1309559T3 (da)	2006-10-02	4-phenyl-pyridinderivater som neurokinin-1-receptorantagonister
NO20032921D0 (no)	2003-06-25	Tynnere for inverterbare emulsjoner
NO20032382D0 (no)	2003-05-27	LFA-1-antagonistforbindelser
DK1440059T3 (da)	2008-07-14	3-azabicyclo(3.1.0)hexanderivater som opioidreceptorantagonister
NO20032142D0 (no)	2003-05-13	Substituerte 2-fenylaminoimidazolin-fenylketon-derivater som IP-antagonister
IS6704A (is)	2003-01-30	Fenoxýbensýlamínafleiður sem valvísir serótónín endurupptöku hindrar
DE60209431D1 (de)	2006-04-27	Sitzstruktur
DK1305319T3 (da)	2006-08-14	4-phenyl-pyridinderivater som neurokinin-1-receptorantagonister
DE60219736D1 (de)	2007-06-06	Hydrierverfahren
DE50213154D1 (de)	2009-02-05	Sitz

Legal Events

Date	Code	Title	Description
2006-01-30	FC2A	Withdrawal, rejection or dismissal of laid open patent application