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NO20026160D0 - Preparater med langvarig frigivelse av kinolonantibiotika og fremgangsmåterfor fremstilling derav - Google Patents

Preparater med langvarig frigivelse av kinolonantibiotika og fremgangsmåterfor fremstilling derav

Info

Publication number
NO20026160D0
NO20026160D0 NO20026160A NO20026160A NO20026160D0 NO 20026160 D0 NO20026160 D0 NO 20026160D0 NO 20026160 A NO20026160 A NO 20026160A NO 20026160 A NO20026160 A NO 20026160A NO 20026160 D0 NO20026160 D0 NO 20026160D0
Authority
NO
Norway
Prior art keywords
preparation
methods
prolonged release
quinolone antibiotics
quinolone
Prior art date
Application number
NO20026160A
Other languages
English (en)
Other versions
NO20026160L (no
NO325415B1 (no
Inventor
Venkata-Rangarao Kanikanti
Roland Rupp
Wolfgang Weber
Peter Deuringer
Jan-Olav Henck
Heino Stass
Takaaki Nishioka
Yoshifumi Katakawa
Chika Taniguchi
Hitoshi Ichihashi
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO20026160L publication Critical patent/NO20026160L/no
Publication of NO20026160D0 publication Critical patent/NO20026160D0/no
Publication of NO325415B1 publication Critical patent/NO325415B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO20026160A 2000-06-26 2002-12-20 Preparater med langvarig frigivelse av kinolonantibiotika og fremgangsmater for fremstilling derav NO325415B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10031043A DE10031043A1 (de) 2000-06-26 2000-06-26 Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
PCT/EP2001/006695 WO2002000219A1 (de) 2000-06-26 2001-06-13 Retard-zubereitungen von chinolon-antibiotika und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
NO20026160L NO20026160L (no) 2002-12-20
NO20026160D0 true NO20026160D0 (no) 2002-12-20
NO325415B1 NO325415B1 (no) 2008-04-21

Family

ID=7646816

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20026160A NO325415B1 (no) 2000-06-26 2002-12-20 Preparater med langvarig frigivelse av kinolonantibiotika og fremgangsmater for fremstilling derav

Country Status (40)

Country Link
US (3) US7709022B2 (no)
EP (1) EP1296685B1 (no)
JP (1) JP4958373B2 (no)
KR (1) KR100939617B1 (no)
CN (1) CN1273138C (no)
AR (1) AR029688A1 (no)
AT (1) ATE355062T1 (no)
AU (1) AU2001270573A1 (no)
BG (1) BG65914B1 (no)
BR (1) BRPI0111911B8 (no)
CA (1) CA2414271C (no)
CU (1) CU23264B7 (no)
CY (1) CY1107574T1 (no)
CZ (1) CZ301812B6 (no)
DE (2) DE10031043A1 (no)
DK (1) DK1296685T3 (no)
DO (1) DOP2001000199A (no)
EE (1) EE04992B1 (no)
ES (1) ES2282270T3 (no)
GT (1) GT200100126A (no)
HN (1) HN2001000132A (no)
HR (1) HRP20030050B1 (no)
HU (1) HU229806B1 (no)
IL (2) IL153333A0 (no)
MA (1) MA25761A1 (no)
MX (1) MXPA02012727A (no)
MY (1) MY140994A (no)
NO (1) NO325415B1 (no)
NZ (1) NZ523352A (no)
PE (1) PE20020207A1 (no)
PL (1) PL203710B1 (no)
PT (1) PT1296685E (no)
RU (1) RU2332204C2 (no)
SI (1) SI1296685T1 (no)
SK (1) SK287384B6 (no)
SV (1) SV2002000505A (no)
TW (1) TWI279232B (no)
UA (1) UA83616C2 (no)
WO (1) WO2002000219A1 (no)
ZA (1) ZA200210350B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
KR100564229B1 (ko) * 2002-06-25 2006-03-28 (주)마이크로 사이언스 테크 항균성 또는 항응혈성 의료용품 및 이의 제조방법
PT1594500E (pt) * 2003-02-10 2010-12-17 Bayer Schering Pharma Ag Tratamento para doenças bacterianas dos órgãos respiratórios por aplicação local de fluoroquinolonas
WO2004073729A1 (ja) * 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
MXPA05010379A (es) 2003-03-27 2006-05-31 Bioactis Ltd Aparato para administrar una medicina en polvo en la cavidad intranasal.
CA2532714C (en) * 2003-08-04 2010-11-16 Kyorin Pharmaceutical Co., Ltd. Oral sustained-release tablet comprising 4-(2-methyl-1-imidazolyl)-2,2-diphenylbutylamide
US7943585B2 (en) * 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
WO2006007323A2 (en) * 2004-06-28 2006-01-19 Alza Corporation Dosage forms for low solubility and/or low dissolution rate free acid pharmaceutical agents
US20080206329A1 (en) * 2004-12-03 2008-08-28 Sanjay Verma Modified Release Ciprofloxacin Compositions
DK1868581T3 (da) * 2005-04-11 2012-07-09 Abbott Lab Farmaceutiske sammensætninger med forbedrede opløsningsprofiler til dårligt opløselige lægemidler
EP1880722B1 (en) * 2006-07-19 2010-03-17 Tabuk Pharmaceutical Manufacturing Co. Pharmaceutical compositions of ciprofloxacin
WO2008078730A1 (ja) 2006-12-26 2008-07-03 Translational Research, Ltd. 経鼻投与用製剤
JP2011515400A (ja) * 2008-03-21 2011-05-19 マイラン・ファーマシューティカルズ・インコーポレーテッド ワックスを含有する持続放出性製剤
KR101697800B1 (ko) 2009-02-13 2017-01-18 로마크 레버러토리즈, 엘.씨. 니타족사니드의 서방성 제약 제형
EP2429495A4 (en) * 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd INTRANASAL PHARMACEUTICAL COMPOSITION WITH IMPROVED PHARMACOKINETICS
US11033624B2 (en) * 2010-06-02 2021-06-15 Novaflux Inc. Medical item for prevention and treatment of ear infection
CN102247313A (zh) * 2010-06-11 2011-11-23 北京润德康医药技术有限公司 一种以莫西沙星为活性成分的口服缓释固体制剂
WO2015168642A1 (en) 2014-05-02 2015-11-05 Labib Mohamed E Drug-releasing device usable in mucosal body cavities
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
EP4419099A4 (en) * 2021-10-19 2025-09-24 Neurosense Therapeutics Ltd COMPOSITIONS COMPRISING CIPROFLOXACIN AND CELECOXIB
CN120815189A (zh) * 2025-09-18 2025-10-21 浙江奥翔药业股份有限公司 一种西他沙星包衣片的包衣液配制方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2951792A (en) * 1959-11-18 1960-09-06 Smith Kline French Lab Sustained release pharmaceutical tablets
FR2100858B1 (no) 1970-07-03 1975-06-06 Daiichi Seiyaku Co
US4122157A (en) * 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
US4293539A (en) * 1979-09-12 1981-10-06 Eli Lilly And Company Controlled release formulations and method of treatment
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
DE3142854A1 (de) 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4530928A (en) * 1982-01-13 1985-07-23 Merck & Co., Inc. Quinoline carboxylic acid complexes with guanidinium carbonate
US4440740A (en) * 1982-04-26 1984-04-03 Merck & Co., Inc. α-Keto aldehydes as enhancing agents of gastro-intestinal drug absorption
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
IT1198386B (it) 1982-07-06 1988-12-21 Lepetit Spa Un prodotto a rilascio protratto contenente il suloctidile
IL70071A (en) 1982-11-01 1987-12-31 Merrell Dow Pharma Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient
US4478822A (en) * 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4639458A (en) * 1985-01-22 1987-01-27 Merck & Co., Inc. Tablet and formulation
NL8500724A (nl) * 1985-03-13 1986-10-01 Univ Groningen Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
FR2585246A1 (fr) * 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US5188840A (en) * 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
US4734285A (en) * 1985-10-28 1988-03-29 The Dow Chemical Company Sustained release compositions
IT1188212B (it) * 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US5286754A (en) * 1986-01-21 1994-02-15 Bayer Aktiengesellschaft Pharmaceutical formulations of ciprofloxacin
DE3601566A1 (de) * 1986-01-21 1987-07-23 Bayer Ag Pharmazeutische zubereitungen von ciprofloxacin
JPS62195323A (ja) * 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
DE3775880D1 (no) 1986-09-18 1992-02-20 London School Of Pharmacy Innovations Ltd., London, Gb
US4869908A (en) * 1987-01-09 1989-09-26 K.V. Pharmaceutical Co. Fibre formulations
US4786503A (en) * 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
US5200193A (en) * 1987-04-22 1993-04-06 Mcneilab, Inc. Pharmaceutical sustained release matrix and process
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
US5472710A (en) * 1988-04-16 1995-12-05 Schwarz Pharma Ag Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture
US5032406A (en) * 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
IT1237904B (it) * 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
JPH0624959A (ja) * 1991-10-04 1994-02-01 Bayer Yakuhin Kk 胃内浮遊型薬物徐放性固形製剤
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
JP2958731B2 (ja) * 1992-02-14 1999-10-06 日本特殊陶業株式会社 酸化アルミニウム基焼結体及びその製造方法
US5582837A (en) * 1992-03-25 1996-12-10 Depomed, Inc. Alkyl-substituted cellulose-based sustained-release oral drug dosage forms
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
IT1256393B (it) * 1992-11-17 1995-12-04 Inverni Della Beffa Spa Forme matriciali multistrato per il rilascio controllato di principi attivi
JP2686215B2 (ja) 1993-04-28 1997-12-08 信越化学工業株式会社 徐放性錠剤
IT1264696B1 (it) 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
DE4406424A1 (de) * 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
US5464633A (en) * 1994-05-24 1995-11-07 Jagotec Ag Pharmaceutical tablets releasing the active substance after a definite period of time
US5900425A (en) * 1995-05-02 1999-05-04 Bayer Aktiengesellschaft Pharmaceutical preparations having controlled release of active compound and processes for their preparation
CN1048628C (zh) 1995-07-06 2000-01-26 东北制药总厂 环丙沙星注射液的制备方法
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US5972389A (en) * 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
US5891474A (en) * 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
EP0998271B3 (en) * 1997-06-06 2014-10-29 Depomed, Inc. Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
IN186245B (no) * 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
EP1017392B1 (de) * 1997-09-25 2002-07-17 Bayer Aktiengesellschaft Arzneimittelformulierung mit kontrollierter wirkstofffreisetzung
PA8466701A1 (es) * 1998-01-21 2000-09-29 Pfizer Prod Inc Comprimido de mesilato de trovafloxacino
ATE245414T1 (de) 1998-09-14 2003-08-15 Ranbaxy Lab Ltd Oral verabreichtes system zur zeitlich und räumlich gesteuerten arzneistoffabgabe
EP1790334A3 (en) 1999-11-02 2008-02-20 Depomed, Inc. Pharmacological inducement of the fed mode for enhanced drug administration to the stomach
MXPA02007254A (es) 2000-02-04 2002-12-09 Depomed Inc Forma de dosis de cubierta-y-nucleo que se aproxima a liberacion de droga de orden cero.
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US6780057B2 (en) * 2001-12-21 2004-08-24 Intel Corporation Coaxial dual pin sockets for high speed I/O applications

Also Published As

Publication number Publication date
DOP2001000199A (es) 2002-05-15
PE20020207A1 (es) 2002-04-27
MA25761A1 (fr) 2003-04-01
PL203710B1 (pl) 2009-11-30
WO2002000219A1 (de) 2002-01-03
PT1296685E (pt) 2007-05-31
HUP0300953A3 (en) 2009-04-28
SK18212002A3 (sk) 2003-04-01
CU23264B7 (es) 2008-03-14
MY140994A (en) 2010-02-12
KR100939617B1 (ko) 2010-02-01
HRP20030050B1 (en) 2011-07-31
AR029688A1 (es) 2003-07-10
US20070065509A1 (en) 2007-03-22
NO20026160L (no) 2002-12-20
CA2414271A1 (en) 2002-12-23
PL360632A1 (en) 2004-09-20
RU2332204C2 (ru) 2008-08-27
ZA200210350B (en) 2004-02-10
DE10031043A1 (de) 2002-02-14
SK287384B6 (sk) 2010-08-09
NO325415B1 (no) 2008-04-21
SI1296685T1 (sl) 2007-06-30
US20040024018A1 (en) 2004-02-05
BG65914B1 (bg) 2010-05-31
KR20030023883A (ko) 2003-03-20
AU2001270573A1 (en) 2002-01-08
CZ301812B6 (cs) 2010-06-30
US7709022B2 (en) 2010-05-04
BR0111911A (pt) 2003-05-13
GT200100126A (es) 2002-01-31
EP1296685B1 (de) 2007-02-28
EP1296685A1 (de) 2003-04-02
CZ20024216A3 (cs) 2003-04-16
US20070237824A1 (en) 2007-10-11
UA83616C2 (uk) 2008-08-11
ATE355062T1 (de) 2006-03-15
CA2414271C (en) 2005-09-27
DK1296685T3 (da) 2007-05-07
EE200200707A (et) 2004-08-16
DE50112123D1 (de) 2007-04-12
US7780986B2 (en) 2010-08-24
CY1107574T1 (el) 2013-03-13
HU229806B1 (en) 2014-07-28
MXPA02012727A (es) 2003-05-14
NZ523352A (en) 2004-08-27
TWI279232B (en) 2007-04-21
CN1273138C (zh) 2006-09-06
BRPI0111911B1 (pt) 2015-08-25
SV2002000505A (es) 2002-12-02
ES2282270T3 (es) 2007-10-16
BRPI0111911B8 (pt) 2021-05-25
HK1058479A1 (en) 2004-05-21
HUP0300953A2 (hu) 2003-08-28
IL153333A0 (en) 2003-07-06
EE04992B1 (et) 2008-04-15
HRP20030050A2 (en) 2004-06-30
US8187632B2 (en) 2012-05-29
IL153333A (en) 2010-05-31
HN2001000132A (es) 2001-09-11
CN1438889A (zh) 2003-08-27
JP2004504278A (ja) 2004-02-12
JP4958373B2 (ja) 2012-06-20
BG107372A (bg) 2003-09-30

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