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NO20013088D0 - 1,2-annelerte kinolinderivater - Google Patents

1,2-annelerte kinolinderivater

Info

Publication number
NO20013088D0
NO20013088D0 NO20013088A NO20013088A NO20013088D0 NO 20013088 D0 NO20013088 D0 NO 20013088D0 NO 20013088 A NO20013088 A NO 20013088A NO 20013088 A NO20013088 A NO 20013088A NO 20013088 D0 NO20013088 D0 NO 20013088D0
Authority
NO
Norway
Prior art keywords
annealed
quinoline derivatives
quinoline
derivatives
annealed quinoline
Prior art date
Application number
NO20013088A
Other languages
English (en)
Other versions
NO20013088L (no
NO318922B1 (no
Inventor
Patrick Rene Angibaud
Marc Gaston Venet
Xavier Marc Bourdrez
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20013088L publication Critical patent/NO20013088L/no
Publication of NO20013088D0 publication Critical patent/NO20013088D0/no
Publication of NO318922B1 publication Critical patent/NO318922B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
NO20013088A 1998-12-23 2001-06-21 1,2-annelerte kinolinderivater NO318922B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204444 1998-12-23
PCT/EP1999/010214 WO2000039082A2 (en) 1998-12-23 1999-12-17 1,2-annelated quinoline derivatives

Publications (3)

Publication Number Publication Date
NO20013088L NO20013088L (no) 2001-06-21
NO20013088D0 true NO20013088D0 (no) 2001-06-21
NO318922B1 NO318922B1 (no) 2005-05-23

Family

ID=8234557

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013088A NO318922B1 (no) 1998-12-23 2001-06-21 1,2-annelerte kinolinderivater

Country Status (32)

Country Link
US (2) US6458800B1 (no)
EP (1) EP1140935B1 (no)
JP (1) JP4725940B2 (no)
KR (2) KR100818541B1 (no)
CN (1) CN1178938C (no)
AR (1) AR021995A1 (no)
AT (1) ATE240327T1 (no)
AU (1) AU765437B2 (no)
BG (1) BG65124B1 (no)
BR (1) BR9916827A (no)
CA (1) CA2355717C (no)
CZ (1) CZ302374B6 (no)
DE (1) DE69907964T2 (no)
DK (1) DK1140935T3 (no)
EA (1) EA004542B1 (no)
EE (1) EE04962B1 (no)
ES (1) ES2200591T3 (no)
HK (1) HK1038746B (no)
HR (1) HRP20010454B1 (no)
HU (1) HU229404B1 (no)
ID (1) ID29241A (no)
IL (2) IL143859A0 (no)
NO (1) NO318922B1 (no)
PL (1) PL199080B1 (no)
PT (1) PT1140935E (no)
SI (1) SI1140935T1 (no)
SK (1) SK286072B6 (no)
TR (1) TR200101961T2 (no)
TW (1) TW531533B (no)
UA (1) UA71592C2 (no)
WO (1) WO2000039082A2 (no)
ZA (1) ZA200105136B (no)

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JP5491681B2 (ja) * 2000-02-04 2014-05-14 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 乳ガンの治療のためのファルネシルタンパク質トランスフェラーゼ阻害剤
EP1267848B1 (en) 2000-02-24 2007-10-17 Janssen Pharmaceutica N.V. Dosing regimen comprising a farnesyl protein transferase inhibitor for the treatment of cancer
WO2001064196A2 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with vinca alkaloids
JP2003525246A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 白金化合物とのファルネシルタンパク質トランスフェラーゼ阻害剤の組み合わせ剤
EP1261341A2 (en) * 2000-02-29 2002-12-04 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with camptothecin compounds
AU2001244167A1 (en) * 2000-02-29 2001-09-12 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
JP2003525244A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗腫瘍性アルキル化剤とのファルネシルタンパク質トランスフェラーゼ阻害剤組み合わせ剤
JP2003525238A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗腫瘍性ポドフィロトキシン誘導体とのファルネシルタンパク質トランスフェラーゼ阻害剤組み合わせ剤
JP2003525255A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ファルネシルタンパク質トランスフェラーゼ阻害剤とさらなる抗癌剤との組み合わせ剤
WO2001064218A2 (en) * 2000-02-29 2001-09-07 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations
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US20030181473A1 (en) * 2000-02-29 2003-09-25 Palmer Peter Albert Farnesyl protein transferase inhibitor combinations with taxane compounds
US20030186925A1 (en) * 2000-02-29 2003-10-02 Palmer Peter Albert Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives
JO2361B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Enaniumer 1,2-anylated quinoline inhibitor for the transporter - farnesyl
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US7196094B2 (en) * 2000-09-25 2007-03-27 Janssen Pharmaceutica, N.V. Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives
AU2001293829A1 (en) * 2000-09-25 2002-04-02 Janssen Pharmaceutica N.V. Farnesyl transferase inhibiting 6-((substituted phenyl)methyl)-quinoline and quinazoline derivatives
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EP1332133B1 (en) * 2000-10-02 2008-07-09 Janssen Pharmaceutica N.V. Metabotropic glutamate receptor antagonists
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US20040157773A1 (en) * 2001-04-25 2004-08-12 End David William Farnesyl protein transferase inhibitors for treating cachexia
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US20030125268A1 (en) * 2002-08-28 2003-07-03 Rybak Mary Ellen Margaret Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives
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US8697716B2 (en) 2006-04-20 2014-04-15 Janssen Pharmaceutica Nv Method of inhibiting C-KIT kinase
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NZ593090A (en) 2008-11-13 2013-06-28 Link Medicine Corp Azaquinolinone derivatives and uses thereof
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CN104093709B (zh) * 2012-02-13 2017-09-22 霍夫曼-拉罗奇有限公司 作为醛固酮合酶抑制剂的咪唑基酮衍生物
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US9221804B2 (en) 2013-10-15 2015-12-29 Janssen Pharmaceutica Nv Secondary alcohol quinolinyl modulators of RORγt
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
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Also Published As

Publication number Publication date
SI1140935T1 (en) 2003-10-31
UA71592C2 (uk) 2004-12-15
JP4725940B2 (ja) 2011-07-13
TR200101961T2 (tr) 2001-12-21
CZ20012142A3 (cs) 2002-01-16
AR021995A1 (es) 2002-09-04
KR100818541B1 (ko) 2008-04-02
KR100712226B1 (ko) 2007-04-27
EP1140935B1 (en) 2003-05-14
AU765437B2 (en) 2003-09-18
WO2000039082A3 (en) 2000-10-26
ID29241A (id) 2001-08-16
HUP0104582A2 (hu) 2002-04-29
IL143859A0 (en) 2002-04-21
DK1140935T3 (da) 2003-09-01
NO20013088L (no) 2001-06-21
ZA200105136B (en) 2002-06-21
CA2355717A1 (en) 2000-07-06
NO318922B1 (no) 2005-05-23
AU2795300A (en) 2000-07-31
HRP20010454A2 (en) 2002-06-30
DE69907964D1 (de) 2003-06-18
DE69907964T2 (de) 2004-02-19
IL143859A (en) 2008-04-13
HUP0104582A3 (en) 2002-12-28
BG105631A (en) 2002-02-28
ATE240327T1 (de) 2003-05-15
CA2355717C (en) 2011-02-08
HRP20010454B1 (en) 2004-06-30
EP1140935A2 (en) 2001-10-10
SK286072B6 (sk) 2008-02-05
US6914066B2 (en) 2005-07-05
CN1331693A (zh) 2002-01-16
JP2002533435A (ja) 2002-10-08
HU229404B1 (en) 2013-12-30
WO2000039082A2 (en) 2000-07-06
EE04962B1 (et) 2008-02-15
EA004542B1 (ru) 2004-06-24
PL349504A1 (en) 2002-07-29
CN1178938C (zh) 2004-12-08
SK8732001A3 (en) 2002-02-05
US6458800B1 (en) 2002-10-01
BR9916827A (pt) 2001-10-16
KR20010087396A (ko) 2001-09-15
PT1140935E (pt) 2003-10-31
PL199080B1 (pl) 2008-08-29
CZ302374B6 (cs) 2011-04-20
BG65124B1 (bg) 2007-03-30
HK1038746A1 (en) 2002-03-28
KR20060117380A (ko) 2006-11-16
ES2200591T3 (es) 2004-03-01
EE200100318A (et) 2002-10-15
EA200100708A1 (ru) 2001-12-24
TW531533B (en) 2003-05-11
HK1038746B (en) 2003-09-05
US20030119843A1 (en) 2003-06-26

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