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MX9300662A - Derivados fosfonooxi y carbonato de taxol - Google Patents

Derivados fosfonooxi y carbonato de taxol

Info

Publication number
MX9300662A
MX9300662A MX9300662A MX9300662A MX9300662A MX 9300662 A MX9300662 A MX 9300662A MX 9300662 A MX9300662 A MX 9300662A MX 9300662 A MX9300662 A MX 9300662A MX 9300662 A MX9300662 A MX 9300662A
Authority
MX
Mexico
Prior art keywords
taxol
phosphonooxi
carbonate
derivatives
formula
Prior art date
Application number
MX9300662A
Other languages
English (en)
Inventor
Yasutsugu Ueda
Henry Wong
Vittorio Farina
Amarendra Mikkilineni
Dolatrai M Vyas
Terrence Doyle
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MX9300662A publication Critical patent/MX9300662A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
    • C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • H10W70/047—

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describe un derivado de taxol de la fórmula (I), o una sal farmecéuticamente aceptable del mismo. La presente invención proporciona compuestos que tienen actividades antitumorales.
MX9300662A 1992-02-13 1993-02-08 Derivados fosfonooxi y carbonato de taxol MX9300662A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83662392A 1992-02-13 1992-02-13
US83662192A 1992-02-13 1992-02-13
US07/981,151 US5272171A (en) 1992-02-13 1992-11-24 Phosphonooxy and carbonate derivatives of taxol

Publications (1)

Publication Number Publication Date
MX9300662A true MX9300662A (es) 1993-09-01

Family

ID=27420260

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300662A MX9300662A (es) 1992-02-13 1993-02-08 Derivados fosfonooxi y carbonato de taxol

Country Status (15)

Country Link
US (1) US5272171A (es)
EP (1) EP0558959B1 (es)
JP (1) JP3261548B2 (es)
AT (1) ATE151762T1 (es)
AU (1) AU651027B2 (es)
CA (1) CA2088931C (es)
DE (1) DE69309753T2 (es)
DK (1) DK0558959T3 (es)
ES (1) ES2099851T3 (es)
FI (1) FI107261B (es)
GR (1) GR3023928T3 (es)
HU (1) HU221842B1 (es)
MX (1) MX9300662A (es)
NO (1) NO306727B1 (es)
NZ (1) NZ245819A (es)

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CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels

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HU9300274D0 (en) 1993-04-28
HU221842B1 (hu) 2003-02-28
DK0558959T3 (da) 1997-06-16
NZ245819A (en) 1994-11-25
CA2088931A1 (en) 1993-08-14
EP0558959B1 (en) 1997-04-16
ATE151762T1 (de) 1997-05-15
FI930491A7 (fi) 1993-08-14
JPH061782A (ja) 1994-01-11
EP0558959A1 (en) 1993-09-08
HUT63400A (en) 1993-08-30
US5272171A (en) 1993-12-21
DE69309753D1 (de) 1997-05-22
NO930388D0 (no) 1993-02-04
FI107261B (fi) 2001-06-29
JP3261548B2 (ja) 2002-03-04
AU3215693A (en) 1993-08-19
CA2088931C (en) 2002-04-30
NO306727B1 (no) 1999-12-13
AU651027B2 (en) 1994-07-07
DE69309753T2 (de) 1997-12-11
ES2099851T3 (es) 1997-06-01
NO930388L (no) 1993-08-16
FI930491A0 (fi) 1993-02-04
GR3023928T3 (en) 1997-09-30

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