[go: up one dir, main page]

MX9300584A - Mezcla de oligosacaridos sulfatados, procedimiento para su preparacion y composicion farmaceutica que la contiene. - Google Patents

Mezcla de oligosacaridos sulfatados, procedimiento para su preparacion y composicion farmaceutica que la contiene.

Info

Publication number
MX9300584A
MX9300584A MX9300584A MX9300584A MX9300584A MX 9300584 A MX9300584 A MX 9300584A MX 9300584 A MX9300584 A MX 9300584A MX 9300584 A MX9300584 A MX 9300584A MX 9300584 A MX9300584 A MX 9300584A
Authority
MX
Mexico
Prior art keywords
preparation
procedure
mixture
pharmaceutical composition
composition containing
Prior art date
Application number
MX9300584A
Other languages
English (en)
Inventor
Andre Uzan
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of MX9300584A publication Critical patent/MX9300584A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0041—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención se refiere a nuevas mezclas de oligosacáridos sulfatados de masa molecular reducida, que presentan la estructura general de oligosacáridos constituyentes de la heparina, también se refiere a su preparación y a las composiciones farmacéuticas que los contienen.
MX9300584A 1992-02-07 1993-02-03 Mezcla de oligosacaridos sulfatados, procedimiento para su preparacion y composicion farmaceutica que la contiene. MX9300584A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9201383A FR2687158B1 (fr) 1992-02-07 1992-02-07 Polysaccharides sulfates, procede de preparation, composition pharmaceutique et utilisation.

Publications (1)

Publication Number Publication Date
MX9300584A true MX9300584A (es) 1993-08-01

Family

ID=9426428

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300584A MX9300584A (es) 1992-02-07 1993-02-03 Mezcla de oligosacaridos sulfatados, procedimiento para su preparacion y composicion farmaceutica que la contiene.

Country Status (17)

Country Link
EP (1) EP0625166B1 (es)
JP (1) JP3218039B2 (es)
KR (1) KR950700334A (es)
AT (1) ATE157991T1 (es)
AU (1) AU671817B2 (es)
CA (1) CA2126241C (es)
DE (1) DE69313826T2 (es)
DK (1) DK0625166T3 (es)
ES (1) ES2109478T3 (es)
FI (1) FI106034B (es)
FR (1) FR2687158B1 (es)
GR (1) GR3024695T3 (es)
HU (1) HU214327B (es)
MX (1) MX9300584A (es)
NO (1) NO307466B1 (es)
NZ (1) NZ249165A (es)
WO (1) WO1993016112A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744457A (en) * 1995-03-31 1998-04-28 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US6001820A (en) * 1995-03-31 1999-12-14 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
EP0735050B1 (en) * 1995-03-31 2002-09-25 Hamilton Civic Hospitals Research Development, Inc. Compositions for inhibiting thrombogenesis
US5763427A (en) * 1995-03-31 1998-06-09 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5767269A (en) * 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
US6075013A (en) * 1997-06-06 2000-06-13 Hamilton Civic Hospitals Research Development Inc. Modified low molecular weight heparin that inhibits clot associated coagulation factors
AU2003225724A1 (en) 2002-03-11 2003-09-29 Momenta Pharmaceuticals, Inc. Analysis of sulfated polysaccharides
EP2019843A2 (en) * 2006-05-25 2009-02-04 Momenta Pharmaceuticals, Inc. Low molecular weight heparin composition and uses thereof
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
US8932867B2 (en) * 2010-09-14 2015-01-13 University Of Miyazaki High purity heparin and production method therefor
US9068957B2 (en) 2011-02-21 2015-06-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2945595A1 (de) * 1979-11-12 1981-05-21 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur herstellung von niedermolekularem heparin bzw. seinen salzen
FR2622450B1 (fr) * 1987-11-03 1991-02-22 Sanofi Sa Association heparine/dermatane sulfate
EP0337327A1 (en) * 1988-04-09 1989-10-18 Bioiberica, S.A. Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin
FR2663639B1 (fr) * 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
FR2675806B1 (fr) * 1991-04-23 1994-06-10 Rhone Poulenc Rorer Sa Polysaccharides sulfates, procede de preparation, composition pharmaceutique et utilisation.

Also Published As

Publication number Publication date
NZ249165A (en) 1996-01-26
HU214327B (hu) 1998-03-02
DE69313826T2 (de) 1998-02-12
EP0625166B1 (fr) 1997-09-10
HU9401994D0 (en) 1994-09-28
ES2109478T3 (es) 1998-01-16
FR2687158A1 (fr) 1993-08-13
GR3024695T3 (en) 1997-12-31
CA2126241C (fr) 2004-06-22
JPH07503496A (ja) 1995-04-13
HUT67878A (en) 1995-05-29
EP0625166A1 (fr) 1994-11-23
FI943642A0 (fi) 1994-08-05
FR2687158B1 (fr) 1995-06-30
ATE157991T1 (de) 1997-09-15
DK0625166T3 (da) 1998-02-02
JP3218039B2 (ja) 2001-10-15
FI106034B (fi) 2000-11-15
NO942897D0 (es) 1994-08-04
FI943642L (fi) 1994-08-05
NO942897L (no) 1994-08-04
AU3505193A (en) 1993-09-03
DE69313826D1 (de) 1997-10-16
WO1993016112A1 (fr) 1993-08-19
AU671817B2 (en) 1996-09-12
KR950700334A (ko) 1995-01-16
NO307466B1 (no) 2000-04-10
CA2126241A1 (fr) 1993-08-19

Similar Documents

Publication Publication Date Title
ES2099145T3 (es) Heparosanos n,o-sulfatados, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
ES2144192T3 (es) Nuevos derivados de 1-fenil-2-dimetil-amino-metil-ciclohexan-1-ol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
MX9204354A (es) Compuestos heterociclicos de 5 miembros, procedimiento para prepararlos y composiciones farmaceuticas que los contienen.
MX9709874A (es) N-(INDOL-2-CARBONIL) beta-ALANILAMIDAS SUSTITUIDAS Y DERIVADOS COMO INHIBIDORES DE GLUCOGENO FOSFORILASA, USO DE LOS MISMOS Y COMPOSICIONES QUE LOS CONTIENEN.
ATE26281T1 (de) Depolymerisiertes und supersulfatiertes heparin, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zusammensetzungen.
MX9305769A (es) Nuevos derivados de analogos del taxol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
AR003940A1 (es) Nuevas 1-fenilpirazol-3-carboxamidas substituidas que tienen una gran afinidad por los receptores humanos de la neurotensina, un procedimiento parasu preparacion y composiciones farmaceuticas que las contienen como principios activos.
MX9100990A (es) Compuesto monohidrato de furoato de mometasona,al procedimiento para su preparacion y a las composiciones farmaceuticas
MX9207394A (es) Esteroides de 17-espirofuran-3'-ilideno.
ITMI920405A0 (it) Derivati polisaccarici di eparina eparan solfato loro frazioni e frammenti procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
MX9203394A (es) Benzazepinas substituidas, su preparacion y composiciones farmaceuticas que contienen las mismas.
SE8902326L (sv) Karboxamidfoereningar, foerfaranden foer framstaellning av dem och farmceutiska kompositioner som innehaaller dem
ES2126766T3 (es) 7-azaindol-3-ilcarboxiamidas de tropilo como agente antitusivo.
MX9203114A (es) Nuevos derivados morfolino de daunorubicina y doxorubicina y composiciones farmaceuticas que los contienen.
AR005999A1 (es) Nuevos derivados de eritromicina, su procedimiento de preparacion, composiciones farmaceuticas y medicamentos
MX9204844A (es) Derivados de benzodioxano, procedimiento para su preparacion composiciones farmaceuticas que los contienen.
MX9300584A (es) Mezcla de oligosacaridos sulfatados, procedimiento para su preparacion y composicion farmaceutica que la contiene.
IT8423564A0 (it) Derivati della 7-carbossimetossi-furo-(3,4-c)-piri dina, loro preparazione e composizioni farmaceutiche che licontengono.
MX9300628A (es) Nuevos derivados de taxano, procedimiento para su preparacion y composicion farmaceutica que los contiene.
AR002247A1 (es) Eleuterobina y analogos de la misma y composiciones que las comprenden.
ES2160308T3 (es) Nuevos derivados amino-metil-heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
MX174530B (es) Derivados de tripeptidos, procedimientos para la preparacion de derivados de tripeptidos y composiciones que los contienen
IT8522327A0 (it) Derivati macromolecolarizzati di cdp-colina, procedimento per laloro preparazione e composizioni farmaceutiche che li contengono.
AR240041A1 (es) Compuestos plaguicidas de 1-fenil-1-(fenoxifenil-prop-1-enil-ciclopropano, composicones que los contienen, procedimientos para su preparacion y compuestos intermediarios para dichos procedimientos.
MX9203732A (es) R-enentiomeros de compuestos de n-propargil-1-aminoindan, su preparacion y composiciones farmaceuticas que contienen los mismos.

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees