ITMI920405A0 - Derivati polisaccarici di eparina eparan solfato loro frazioni e frammenti procedimento per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents
Derivati polisaccarici di eparina eparan solfato loro frazioni e frammenti procedimento per la loro preparazione e composizioni farmaceutiche che li contengonoInfo
- Publication number
- ITMI920405A0 ITMI920405A0 IT92MI405A ITMI920405A ITMI920405A0 IT MI920405 A0 ITMI920405 A0 IT MI920405A0 IT 92MI405 A IT92MI405 A IT 92MI405A IT MI920405 A ITMI920405 A IT MI920405A IT MI920405 A0 ITMI920405 A0 IT MI920405A0
- Authority
- IT
- Italy
- Prior art keywords
- polysacric
- eparan
- heparin
- fractions
- fragments
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical class OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 title 1
- WZHCOOQXZCIUNC-UHFFFAOYSA-N cyclandelate Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C(O)C1=CC=CC=C1 WZHCOOQXZCIUNC-UHFFFAOYSA-N 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920405A IT1254216B (it) | 1992-02-25 | 1992-02-25 | Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
| ES93102527T ES2110015T3 (es) | 1992-02-25 | 1993-02-18 | Derivados de polisacaridos de heparina, sulfato de heparan, sus fracciones y fragmentos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. |
| AT93102527T ATE161273T1 (de) | 1992-02-25 | 1993-02-18 | Polysaccharidderivate von heparin, heparansulfate, ihre fraktionen und fragmente, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, welche diese enthalten |
| DE69315724T DE69315724D1 (de) | 1992-02-25 | 1993-02-18 | Polysaccharidderivate von Heparin, Heparansulfate, ihre Fraktionen und Fragmente, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, welche diese enthalten |
| EP93102527A EP0557887B1 (en) | 1992-02-25 | 1993-02-18 | Polysaccharide derivatives of heparin, heparan sulphate, fraction and fragments thereof, process for their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920405A IT1254216B (it) | 1992-02-25 | 1992-02-25 | Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI920405A0 true ITMI920405A0 (it) | 1992-02-25 |
| ITMI920405A1 ITMI920405A1 (it) | 1993-08-25 |
| IT1254216B IT1254216B (it) | 1995-09-14 |
Family
ID=11362117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI920405A IT1254216B (it) | 1992-02-25 | 1992-02-25 | Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0557887B1 (it) |
| AT (1) | ATE161273T1 (it) |
| DE (1) | DE69315724D1 (it) |
| ES (1) | ES2110015T3 (it) |
| IT (1) | IT1254216B (it) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU688272B2 (en) * | 1992-07-24 | 1998-03-12 | Paringenix, Inc. | Medicameny for inhibiting neutrophil elastase and cathepsin |
| US5668118A (en) * | 1992-07-24 | 1997-09-16 | Cavalier Pharmaceuticals | Method of synthesis of 2-O-desulfated Heparin and use thereof for inhibition of elastase and Cathepspin G |
| US5696100A (en) * | 1992-12-22 | 1997-12-09 | Glycomed Incorporated | Method for controlling O-desulfation of heparin and compositions produced thereby |
| US5583121A (en) * | 1994-01-12 | 1996-12-10 | Michigan State University | Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes |
| US6127347A (en) * | 1994-01-12 | 2000-10-03 | Univ Michigan | Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes |
| US5633233A (en) * | 1995-06-07 | 1997-05-27 | Alberta Research Council | Modified kojibiosides analogues |
| US6217863B1 (en) | 1995-10-30 | 2001-04-17 | Massachusetts Institute Of Technology | Rationally designed polysaccharide lyases derived from heparinase I |
| FR2781485B1 (fr) | 1998-07-21 | 2003-08-08 | Denis Barritault | Polymeres biocompatibles leur procede de preparation et les compositions les contenant |
| US7056504B1 (en) | 1998-08-27 | 2006-06-06 | Massachusetts Institute Of Technology | Rationally designed heparinases derived from heparinase I and II |
| CA2341412A1 (en) | 1998-08-27 | 2000-03-09 | Massachusetts Institute Of Technology | Rationally designed heparinases derived from heparinase i and ii |
| EP1190364A2 (en) | 1999-04-23 | 2002-03-27 | Massachusetts Institute Of Technology | System and method for polymer notation |
| EP1266013B1 (en) | 2000-03-08 | 2014-10-15 | Massachusetts Institute Of Technology | Heparinase iii and uses thereof |
| ATE426805T1 (de) | 2000-09-12 | 2009-04-15 | Massachusetts Inst Technology | Verfahren und produkte, die mit niedermolekularem heparin assoziiert sind |
| AU2000272704A1 (en) * | 2000-09-15 | 2002-03-26 | Boehringer Ingelheim International G.M.B.H | Use of compounds for the treatment of obesity |
| EP1328260A2 (en) | 2000-10-18 | 2003-07-23 | Massachusetts Institute Of Technology | Methods and products related to pulmonary delivery of polysaccharides |
| AU2003225724A1 (en) | 2002-03-11 | 2003-09-29 | Momenta Pharmaceuticals, Inc. | Analysis of sulfated polysaccharides |
| US9139876B1 (en) | 2007-05-03 | 2015-09-22 | Momenta Pharmacueticals, Inc. | Method of analyzing a preparation of a low molecular weight heparin |
| US8592393B2 (en) | 2007-11-02 | 2013-11-26 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
| US9351992B2 (en) | 2007-11-02 | 2016-05-31 | Momenta Pharmaceuticals, Inc. | Non-anticoagulant polysaccharide compositions |
| US8569262B2 (en) | 2007-11-02 | 2013-10-29 | Momenta Pharmaceuticals, Inc. | Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization |
| CN101584705B (zh) * | 2008-05-24 | 2010-10-27 | 鲁南制药集团股份有限公司 | 一种治疗糖尿病及其并发症的药物组合物 |
| CN101584688B (zh) * | 2008-05-24 | 2010-11-10 | 鲁南制药集团股份有限公司 | 一种治疗糖尿病及其并发症的药物组合物 |
| BR112012026542A2 (pt) | 2010-04-16 | 2016-07-12 | Momenta Pharmaceuticals Inc | abordagem seletiva de tecido |
| CN103096870B (zh) | 2010-06-17 | 2017-04-19 | 动量制药公司 | 调节毛发生长的方法和组合物 |
| US9068957B2 (en) | 2011-02-21 | 2015-06-30 | Momenta Pharmaceuticals, Inc. | Evaluating heparin preparations |
| SG10201914117QA (en) | 2012-05-09 | 2020-02-27 | Cantex Pharmaceuticals Inc | Treatment Of Myelosuppression |
| EP3003324A4 (en) | 2013-05-28 | 2017-01-25 | Momenta Pharmaceuticals, Inc. | Pharmaceutical compositions |
| EP3258941A4 (en) | 2015-02-17 | 2018-09-26 | Cantex Pharmaceuticals, Inc. | Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1234508B (it) * | 1988-06-10 | 1992-05-19 | Alfa Wassermann Spa | Derivati eparinici e procedimento per la loro preparazione |
| IT1234826B (it) * | 1989-01-30 | 1992-05-29 | Alfa Wassermann Spa | Derivati eparinici e procedimento per la loro preparazione |
-
1992
- 1992-02-25 IT ITMI920405A patent/IT1254216B/it active
-
1993
- 1993-02-18 ES ES93102527T patent/ES2110015T3/es not_active Expired - Lifetime
- 1993-02-18 DE DE69315724T patent/DE69315724D1/de not_active Expired - Lifetime
- 1993-02-18 AT AT93102527T patent/ATE161273T1/de not_active IP Right Cessation
- 1993-02-18 EP EP93102527A patent/EP0557887B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI920405A1 (it) | 1993-08-25 |
| EP0557887B1 (en) | 1997-12-17 |
| EP0557887A2 (en) | 1993-09-01 |
| IT1254216B (it) | 1995-09-14 |
| ES2110015T3 (es) | 1998-02-01 |
| ATE161273T1 (de) | 1998-01-15 |
| EP0557887A3 (it) | 1994-02-09 |
| DE69315724D1 (de) | 1998-01-29 |
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