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MX2019015895A - Nuevos derivados de azaquinolina. - Google Patents

Nuevos derivados de azaquinolina.

Info

Publication number
MX2019015895A
MX2019015895A MX2019015895A MX2019015895A MX2019015895A MX 2019015895 A MX2019015895 A MX 2019015895A MX 2019015895 A MX2019015895 A MX 2019015895A MX 2019015895 A MX2019015895 A MX 2019015895A MX 2019015895 A MX2019015895 A MX 2019015895A
Authority
MX
Mexico
Prior art keywords
compounds
new
azaquinoline
preparing
pharmaceutical compositions
Prior art date
Application number
MX2019015895A
Other languages
English (en)
Inventor
Hallenbach Werner
Schwarz Hans-Georg
Hübsch Walter
Zhuang Wei
Börngen Kirsten
Köhler Adeline
Görgens Ulrich
Kulke Daniel
Griebenow Nils
Alig Bernd
Ilg Thomas
Böhm Claudia
Heisler Iring
Jana Irina Janssen Isa
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of MX2019015895A publication Critical patent/MX2019015895A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención abarca compuestos de azaquinolina de la fórmula general (I): (ver Fórmula) (I), con A es A1 o A2: (ver Fórmulas), y en la cual T, R1, R2, R3, R4, R5, R6, y Q son como se definen en el presente, procedimientos para la preparación de dichos compuestos, compuestos intermedios útiles para la preparación de dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la elaboración de composiciones farmacéuticas para el tratamiento, control y/o prevención de enfermedades, en especial de infecciones con helmintos, como un único agente o en combinación con otros ingredientes activos.
MX2019015895A 2017-06-30 2018-06-22 Nuevos derivados de azaquinolina. MX2019015895A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17179149 2017-06-30
PCT/EP2018/066776 WO2019002132A1 (en) 2017-06-30 2018-06-22 NEW AZAQUINOLINE DERIVATIVES

Publications (1)

Publication Number Publication Date
MX2019015895A true MX2019015895A (es) 2020-02-07

Family

ID=59269946

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019015895A MX2019015895A (es) 2017-06-30 2018-06-22 Nuevos derivados de azaquinolina.

Country Status (22)

Country Link
US (1) US11485733B2 (es)
EP (1) EP3615527B1 (es)
JP (1) JP7210483B2 (es)
KR (1) KR20200020911A (es)
CN (1) CN110770227B (es)
AR (1) AR112216A1 (es)
AU (1) AU2018293627B2 (es)
CA (1) CA3068350A1 (es)
CL (1) CL2019003892A1 (es)
CO (1) CO2019014484A2 (es)
CR (1) CR20190595A (es)
DK (1) DK3615527T3 (es)
ES (1) ES2984497T3 (es)
IL (1) IL271607B2 (es)
MX (1) MX2019015895A (es)
PE (1) PE20200608A1 (es)
PH (1) PH12019502851A1 (es)
PL (1) PL3615527T3 (es)
TW (1) TWI799429B (es)
UA (1) UA125800C2 (es)
UY (1) UY37789A (es)
WO (1) WO2019002132A1 (es)

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JP7644121B2 (ja) * 2019-12-18 2025-03-11 インターベット インターナショナル ベー． フェー． アザインドール構造を含む駆虫剤化合物
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CN116685584A (zh) * 2020-11-18 2023-09-01 礼蓝动物保健有限公司 用于治疗心丝虫感染的n-(2,3-二氢-1,4-苯并噁嗪-4-基)-3-异丙基-7-(2,3,5-三氟苯基)苯并噻吩-2-甲酰胺衍生物和类似化合物
CN116888124A (zh) * 2020-12-04 2023-10-13 礼蓝动物保健有限公司 二环衍生物
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Also Published As

Publication number Publication date
EP3615527B1 (en) 2024-03-06
US20200131175A1 (en) 2020-04-30
IL271607B1 (en) 2023-03-01
US11485733B2 (en) 2022-11-01
TWI799429B (zh) 2023-04-21
WO2019002132A1 (en) 2019-01-03
JP7210483B2 (ja) 2023-01-23
BR112019028181A2 (pt) 2020-07-07
UA125800C2 (uk) 2022-06-08
NZ759633A (en) 2024-05-31
AU2018293627B2 (en) 2022-07-21
CA3068350A1 (en) 2019-01-03
PE20200608A1 (es) 2020-03-10
DK3615527T3 (da) 2024-05-06
AU2018293627A1 (en) 2019-12-12
UY37789A (es) 2019-01-31
JP2020525444A (ja) 2020-08-27
CR20190595A (es) 2020-03-03
IL271607B2 (en) 2023-07-01
CN110770227B (zh) 2024-03-01
CN110770227A (zh) 2020-02-07
CL2019003892A1 (es) 2020-07-10
PH12019502851A1 (en) 2020-10-19
RU2020103733A (ru) 2021-07-30
AR112216A1 (es) 2019-10-02
TW201904961A (zh) 2019-02-01
CO2019014484A2 (es) 2020-01-17
EP3615527A1 (en) 2020-03-04
ES2984497T3 (es) 2024-10-29
IL271607A (en) 2020-02-27
RU2020103733A3 (es) 2021-10-22
KR20200020911A (ko) 2020-02-26
PL3615527T3 (pl) 2024-07-01

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