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MX2019012750A - Moduladores del receptor s1p para el tratamiento de esclerosis multiple. - Google Patents

Moduladores del receptor s1p para el tratamiento de esclerosis multiple.

Info

Publication number
MX2019012750A
MX2019012750A MX2019012750A MX2019012750A MX2019012750A MX 2019012750 A MX2019012750 A MX 2019012750A MX 2019012750 A MX2019012750 A MX 2019012750A MX 2019012750 A MX2019012750 A MX 2019012750A MX 2019012750 A MX2019012750 A MX 2019012750A
Authority
MX
Mexico
Prior art keywords
multiple sclerosis
receptor modulators
treating multiple
amino
neo
Prior art date
Application number
MX2019012750A
Other languages
English (en)
Inventor
C Hiestand Peter
Schnell Christian
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36888144&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019012750(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2019012750A publication Critical patent/MX2019012750A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a usos de un modulador del receptor S1P, o derivados de 2-amino-propanol, por ejemplo un compuesto que comprende un grupo de la fórmula (X): (ver Fórmula) para el tratamiento o la prevención de neo-angiogénesis asociada con una enfermedad desmielinizante, tal como esclerosis múltiple.
MX2019012750A 2006-06-27 2008-12-16 Moduladores del receptor s1p para el tratamiento de esclerosis multiple. MX2019012750A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0612721.1A GB0612721D0 (en) 2006-06-27 2006-06-27 Organic compounds

Publications (1)

Publication Number Publication Date
MX2019012750A true MX2019012750A (es) 2020-02-03

Family

ID=36888144

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2008016133A MX2008016133A (es) 2006-06-27 2007-06-25 Moduladores del receptor s1p para el tratamiento de esclerosis multiple.
MX2019012750A MX2019012750A (es) 2006-06-27 2008-12-16 Moduladores del receptor s1p para el tratamiento de esclerosis multiple.
MX2022008950A MX2022008950A (es) 2006-06-27 2008-12-16 Moduladores del receptor s1p para el tratamiento de esclerosis multiple.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2008016133A MX2008016133A (es) 2006-06-27 2007-06-25 Moduladores del receptor s1p para el tratamiento de esclerosis multiple.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022008950A MX2022008950A (es) 2006-06-27 2008-12-16 Moduladores del receptor s1p para el tratamiento de esclerosis multiple.

Country Status (20)

Country Link
US (3) US20100168078A1 (es)
EP (4) EP3797765A1 (es)
JP (8) JP2009541386A (es)
KR (6) KR20190030776A (es)
CN (2) CN101478961B (es)
AU (7) AU2007264031C1 (es)
BR (1) BRPI0713985A2 (es)
CA (1) CA2653569C (es)
DE (1) DE15177166T1 (es)
DK (1) DK2959894T3 (es)
ES (1) ES2887042T3 (es)
GB (1) GB0612721D0 (es)
HU (1) HUE059922T4 (es)
LT (1) LT2959894T (es)
MX (3) MX2008016133A (es)
PL (1) PL2959894T3 (es)
PT (1) PT2959894T (es)
RU (1) RU2617502C2 (es)
SI (1) SI2959894T1 (es)
WO (1) WO2008000419A1 (es)

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Also Published As

Publication number Publication date
PT2959894T (pt) 2022-10-18
JP2025016462A (ja) 2025-02-04
HUE059922T4 (hu) 2024-05-28
KR20210010956A (ko) 2021-01-28
JP2023098949A (ja) 2023-07-11
PL2959894T3 (pl) 2022-11-14
KR20170138583A (ko) 2017-12-15
JP2013166761A (ja) 2013-08-29
EP2959894B1 (en) 2022-10-12
DE15177166T1 (de) 2022-01-27
JP2018109018A (ja) 2018-07-12
AU2013200356B2 (en) 2016-09-29
RU2617502C2 (ru) 2017-04-25
AU2016266058A1 (en) 2016-12-22
DK2959894T3 (da) 2022-10-17
HUE059922T2 (hu) 2023-01-28
AU2021202395A1 (en) 2021-05-20
BRPI0713985A2 (pt) 2012-11-20
JP2016185957A (ja) 2016-10-27
EP2959894A1 (en) 2015-12-30
LT2959894T (lt) 2022-11-10
ES2887042T3 (es) 2022-11-14
MX2008016133A (es) 2009-01-15
US20140228446A1 (en) 2014-08-14
AU2007264031C1 (en) 2016-12-15
RU2569732C2 (ru) 2015-11-27
DK2959894T1 (da) 2021-12-20
AU2013200356A1 (en) 2013-02-14
WO2008000419A1 (en) 2008-01-03
CA2653569A1 (en) 2008-01-03
JP7258832B2 (ja) 2023-04-17
AU2018202210A1 (en) 2018-04-26
CN101478961A (zh) 2009-07-08
SI2959894T1 (sl) 2022-11-30
EP2698154A1 (en) 2014-02-19
RU2013131176A (ru) 2015-01-20
JP2021035955A (ja) 2021-03-04
ES2887042T1 (es) 2021-12-21
HUE15177166T1 (hu) 2022-05-28
US9187405B2 (en) 2015-11-17
AU2019219818A1 (en) 2019-09-12
AU2011201844A1 (en) 2011-05-19
KR20150122812A (ko) 2015-11-02
US8741963B2 (en) 2014-06-03
AU2011201844B2 (en) 2012-10-25
GB0612721D0 (en) 2006-08-09
JP6931019B2 (ja) 2021-09-01
CA2653569C (en) 2016-06-21
US20110237682A1 (en) 2011-09-29
PL15177166T1 (pl) 2022-03-07
RU2009102278A (ru) 2010-08-10
CN103550195A (zh) 2014-02-05
JP2009541386A (ja) 2009-11-26
KR20140069178A (ko) 2014-06-09
KR20090024281A (ko) 2009-03-06
HK1214758A1 (en) 2016-08-05
AU2007264031B2 (en) 2011-01-27
US20100168078A1 (en) 2010-07-01
EP2037906A1 (en) 2009-03-25
MX2022008950A (es) 2022-08-11
AU2007264031A1 (en) 2008-01-03
KR20190030776A (ko) 2019-03-22
CN101478961B (zh) 2013-11-27
JP2019167352A (ja) 2019-10-03
EP3797765A1 (en) 2021-03-31

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