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MX2018010425A - Metodos de preparacion de l-glufosinato. - Google Patents

Metodos de preparacion de l-glufosinato.

Info

Publication number
MX2018010425A
MX2018010425A MX2018010425A MX2018010425A MX2018010425A MX 2018010425 A MX2018010425 A MX 2018010425A MX 2018010425 A MX2018010425 A MX 2018010425A MX 2018010425 A MX2018010425 A MX 2018010425A MX 2018010425 A MX2018010425 A MX 2018010425A
Authority
MX
Mexico
Prior art keywords
glufosinate
methods
ppo
making
hydroxy
Prior art date
Application number
MX2018010425A
Other languages
English (en)
Other versions
MX388774B (es
Inventor
Michael Green Brian
Lorraine Gradley Michelle
Original Assignee
Agrimetis Llc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58267184&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2018010425(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agrimetis Llc filed Critical Agrimetis Llc
Publication of MX2018010425A publication Critical patent/MX2018010425A/es
Publication of MX388774B publication Critical patent/MX388774B/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03003—D-Amino-acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01019—4-Aminobutyrate—2-oxoglutarate transaminase (2.6.1.19)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catching Or Destruction (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proveen métodos para la producción de L-glufosinato (también conocido como fosfinotricina o ácido (S)-2-amino-4-(hidroxi(metil) fosfonoil)butanoico). Los métodos comprenden un proceso de dos etapas. La primera etapa comprende la desaminación oxidativa de D-glufosinato en PPO (ácido 2-oxo-4-(hidroxi(metil)fosfinoil)butír ico). La segunda etapa comprende la aminación específica de PPO en L-glufosinato, usando un grupo amina de uno o más donantes de aminas. Mediante la combinación de estas dos reacciones, la proporción de L-glufosinato en una mezcla de L-glufosinato y D-glufosinato puede ser incrementada sustancialmente.
MX2018010425A 2016-03-02 2017-02-28 Métodos de preparación de l-glufosinato. MX388774B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662302421P 2016-03-02 2016-03-02
US201662336989P 2016-05-16 2016-05-16
US201662413240P 2016-10-26 2016-10-26
PCT/US2017/019871 WO2017151573A1 (en) 2016-03-02 2017-02-28 Methods for making l-glufosinate

Publications (2)

Publication Number Publication Date
MX2018010425A true MX2018010425A (es) 2018-11-29
MX388774B MX388774B (es) 2025-03-20

Family

ID=58267184

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018010425A MX388774B (es) 2016-03-02 2017-02-28 Métodos de preparación de l-glufosinato.
MX2021013232A MX2021013232A (es) 2016-03-02 2018-08-29 Metodos de preparacion de l-glufosinato.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021013232A MX2021013232A (es) 2016-03-02 2018-08-29 Metodos de preparacion de l-glufosinato.

Country Status (14)

Country Link
US (11) US9834802B2 (es)
EP (2) EP3423585A1 (es)
JP (3) JP7041066B2 (es)
KR (2) KR20250156185A (es)
CN (3) CN109072261B (es)
AU (2) AU2017227553B2 (es)
BR (1) BR112018067523A8 (es)
CA (1) CA3015081A1 (es)
CL (2) CL2018002454A1 (es)
IL (2) IL261271B2 (es)
MA (1) MA43711A (es)
MX (2) MX388774B (es)
WO (1) WO2017151573A1 (es)
ZA (1) ZA201805680B (es)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250156185A (ko) * 2016-03-02 2025-10-31 바스프 에스이 L-글루포시네이트를 제조하는 방법
EP3654771A1 (en) 2017-07-18 2020-05-27 Agrimetis, LLC Methods for the purification of l-glufosinate
CA3069815A1 (en) * 2017-07-27 2019-01-31 Basf Se Use of herbicidal compositions based on l-glufosinate in tolerant field crops
EP3664606A1 (en) * 2017-08-09 2020-06-17 Basf Se Herbicidal mixtures comprising l-glufosinate or its salt and at least one protoporphyrinogen-ix oxidase inhibitor
EP3440937A1 (en) * 2017-08-09 2019-02-13 Basf Se Herbicidal mixtures comprising l-glufosinate or its salt and a second herbicide
EP3664608A1 (en) * 2017-08-09 2020-06-17 Basf Se Herbicidal mixtures comprising l-glufosinate or its salt and at least one vlcfa inhibitor
EP3440939A1 (en) * 2017-08-09 2019-02-13 Basf Se Herbicidal mixtures comprising l-glufosinate
US11666052B2 (en) 2017-08-09 2023-06-06 Basf Se Herbicidal mixtures comprising L-glufosinate or its salt and at least one bleacher herbicide
US11363818B2 (en) 2017-08-09 2022-06-21 Basf Se Herbicidal mixtures comprising L-glufosinate and their use in soybean cultures
BR122023020932A2 (pt) * 2017-08-09 2024-01-09 Basf Se Uso de uma mistura herbicida, mistura pesticida, composição pesticida e método para controlar a vegetação indesejável
CN107502647B (zh) * 2017-09-15 2020-12-15 浙江大学 一种生物酶法去消旋化制备l-草铵膦的方法
CN110055289B (zh) * 2018-01-19 2020-05-29 上海弈柯莱生物医药科技有限公司 一种l-草铵膦的制备方法
CN110343676B (zh) 2018-04-03 2020-06-23 上海弈柯莱生物医药科技有限公司 一种l-谷氨酸脱氢酶突变体及其应用
TWI851589B (zh) 2018-07-31 2024-08-11 德商拜耳廠股份有限公司 編碼改良之轉胺酶蛋白質之核酸
CN108912167B (zh) * 2018-08-08 2020-07-07 河北威远生物化工有限公司 一种从水解反应液中分离纯化草铵膦的方法
EP3847269A1 (en) * 2018-09-05 2021-07-14 Basf Se Methods for improving yields of l-glufosinate
CN111019916B (zh) * 2018-11-23 2020-12-08 弈柯莱生物科技(上海)股份有限公司 一种d-氨基酸氧化酶突变体及其应用
CN109609475B (zh) * 2018-12-28 2020-10-09 浙江工业大学 草铵膦脱氢酶突变体及其合成l-草铵膦的应用
CN109576236B (zh) * 2018-12-28 2019-12-17 浙江工业大学 一种d-氨基酸氧化酶突变体及其应用
CN109609474B (zh) * 2018-12-28 2020-07-28 浙江工业大学 一种氨基酸脱氢酶突变体及其在合成l-草铵膦中的应用
BR112021013261B1 (pt) 2019-01-11 2024-02-20 Cj Cheiljedang Corporation Método para produzir l-glufosinato
KR102582675B1 (ko) * 2019-01-11 2023-09-25 씨제이제일제당 주식회사 글루포시네이트 제조 방법
CN109609477B (zh) * 2019-01-14 2022-02-18 浙江工业大学 一种α-转氨酶突变体及其在不对称合成L-草铵膦中的应用
CN111172125B (zh) * 2019-03-05 2023-08-08 上海七洲紫岳生物科技有限公司 一种固定化d-氨基酸氧化酶及其制备方法和应用
US12234254B2 (en) 2019-04-16 2025-02-25 Basf Se Methods for producing crystalline L-glufosinate ammonium monohydrate
CN111979208B (zh) 2019-05-23 2023-01-10 弈柯莱生物科技(上海)股份有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN112391438B (zh) * 2019-08-13 2023-01-13 四川利尔生物科技有限公司 一种l-草铵膦或其盐的生产方法
CA3155389A1 (en) * 2019-11-20 2021-05-27 Philip Pentland Herbicidal glufosinate composition
CA3160673A1 (en) * 2019-12-09 2021-06-17 Hunan Lier Biotechnology Co., Ltd. Modified daao and the use thereof
BR112022014758A2 (pt) 2020-01-31 2022-10-11 Basf Se Combinação de herbicidas, composição, métodos para produzir uma combinação de herbicidas, para controlar o crescimento indesejado das plantas e para tratar ou proteger culturas e uso da combinação de herbicidas
BR112022015061A2 (pt) * 2020-01-31 2022-09-20 Basf Se Combinação de herbicidas, composição, métodos para produzir uma combinação de herbicidas, para controlar o crescimento indesejado das plantas, para tratar ou proteger culturas e uso de uma combinação de herbicidas
WO2021151736A1 (en) 2020-01-31 2021-08-05 Basf Se Herbicide combinations comprising glufosinate and fluthiacet-methyl
US20230054749A1 (en) * 2020-01-31 2023-02-23 Basf Se Herbicide Combinations Comprising Glufosinate and Flumiclorac-pentyl
WO2021151753A1 (en) 2020-01-31 2021-08-05 Basf Se Herbicide combinations comprising glufosinate and selected ppo inhibitors
WO2021151752A1 (en) 2020-01-31 2021-08-05 Basf Se Herbicide combinations comprising glufosinate and selected ppo inhibitors
US20230054333A1 (en) 2020-01-31 2023-02-23 Basf Se Herbicide Combinations Comprising Glufosinate and Saflufenacil
US20230088774A1 (en) 2020-01-31 2023-03-23 Basf Se Herbicide Combinations Comprising Glufosinate and Oxadiazon
US20230067406A1 (en) 2020-01-31 2023-03-02 Basf Se Herbicide Combinations Comprising Glufosinate and Flumioxazin
BR112022014809A2 (pt) 2020-01-31 2022-09-20 Basf Se Combinação de herbicidas, composição, métodos para produzir uma combinação de herbicidas, para controlar o crescimento de plantas indesejadas e para tratar ou proteger culturas e uso de uma combinação de herbicidas
US20230091043A1 (en) * 2020-01-31 2023-03-23 Basf Se Herbicide Combinations Comprising Glufosinate and Carfentrazone-Ethyl
BR112022014727A2 (pt) 2020-01-31 2022-10-11 Basf Se Combinação de herbicidas, composição, métodos para produzir uma combinação de herbicidas, para controlar o crescimento indesejado das plantas, para tratar ou proteger culturas em linha e para tratar ou proteger culturas especiais e uso de uma combinação de herbicidas
WO2021151738A1 (en) 2020-01-31 2021-08-05 Basf Se Herbicide combinations comprising glufosinate and epyrifenacil
WO2021151744A1 (en) 2020-01-31 2021-08-05 Basf Se Herbicide combinations comprising glufosinate and oxyfluorfen
US12262715B2 (en) 2020-02-05 2025-04-01 Basf Se Herbicidal mixtures comprising L-glufosinate or its salt and at least one protoporphyrinogen-IX oxidase inhibitor
CN111321193B (zh) * 2020-03-18 2020-11-10 浙江工业大学 一种生物多酶偶联法氧化还原不对称制备l-草铵膦的方法
CN111574559A (zh) * 2020-04-30 2020-08-25 河北威远生物化工有限公司 L-草铵膦酶水解液的后处理方法
JP2023532699A (ja) 2020-07-09 2023-07-31 フーナン リアー バイオテック カンパニー リミテッド 改変型グルタミン酸デヒドロゲナーゼ及びその使用
CN112553285B (zh) * 2020-12-25 2022-10-28 浙江大学杭州国际科创中心 一种ω-转氨酶的应用及生物酶法去消旋化制备L-草铵膦的方法
CN117120625A (zh) 2021-04-01 2023-11-24 巴斯夫欧洲公司 制备l-草铵膦的方法
WO2022207543A1 (en) 2021-04-01 2022-10-06 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate and its phosphoesters
CN113969269B (zh) 2021-04-29 2024-05-03 永农生物科学有限公司 D-氨基酸氧化酶突变体及其在制备l-草铵膦中的应用
CN113295783A (zh) * 2021-05-08 2021-08-24 青岛谱尼测试有限公司 一种精草铵膦衍生转化的检测方法
CN113234767B (zh) * 2021-05-13 2022-05-17 永农生物科学有限公司 制备不含结晶水的l-草铵膦铵盐的固体粉末的方法
EP4105335A1 (en) 2021-06-16 2022-12-21 Evonik Operations GmbH Enzymatic method for the production of l-glufosinate p-alkyl esters
EP4151643A1 (en) 2021-09-16 2023-03-22 Evonik Operations GmbH Improved process for production of phosphoesters of glufosinate precursors
CN118475689A (zh) 2021-12-31 2024-08-09 湖南利尔生物科技有限公司 经修饰的谷氨酸脱氢酶及其应用
CN116555206A (zh) * 2022-01-30 2023-08-08 弈柯莱生物科技(上海)股份有限公司 一种d-氨基酸氧化酶及其在制备l-草铵膦或其中间体中的应用
CN114540440B (zh) * 2022-03-01 2024-09-27 浙江工业大学 一种加压催化制备2-羰基-4-(羟基甲基膦酰基)丁酸的方法
US12398410B2 (en) 2022-03-14 2025-08-26 Evonik Operations Gmbh Enzymatic method for the production of L-glufosinate P-esters
CN115074403B (zh) * 2022-05-18 2025-04-22 湖北泰盛化工有限公司 L-草铵膦的关键中间体4-(甲基羟基磷酰基)-2-羰基丁酸
WO2023222226A1 (en) 2022-05-19 2023-11-23 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate
WO2023222227A1 (en) 2022-05-19 2023-11-23 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate
WO2023232225A1 (en) 2022-05-31 2023-12-07 Evonik Operations Gmbh Enzymatic method for the diastereoselective production of l-glufosinate p-esters
WO2024002741A1 (en) * 2022-06-29 2024-01-04 Basf Se Herbicidal mixtures comprising l-glufosinate or its salt and a second herbicide
CN119894375A (zh) * 2022-09-20 2025-04-25 巴斯夫欧洲公司 储存稳定的草铵膦配制品
WO2024061456A1 (en) 2022-09-21 2024-03-28 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate and its phosphoesters
WO2024061455A1 (en) 2022-09-21 2024-03-28 Evonik Operations Gmbh Enzymatic method for producing l-glufosinate and its phosphoesters
CN115896054A (zh) * 2022-10-11 2023-04-04 湖南福来格生物技术有限公司 一种d-氨基酸氧化酶突变体及其应用
CN116789695B (zh) * 2022-11-17 2024-03-29 永农生物科学有限公司 一种草铵膦的制备方法
CN115896195B (zh) * 2022-12-27 2024-07-02 河北威远生物化工有限公司 一种l-草铵膦的制备方法
EP4655280A1 (en) * 2023-01-25 2025-12-03 Vulpes Agricultural Corp. Optically active amino acid salts and method for their preparation
AU2024229805A1 (en) * 2023-03-01 2025-08-28 Hunan Lier Biotech Co., Ltd. A process preparing L-glufosinate directly from L-homoserine
AR132230A1 (es) * 2023-03-27 2025-06-04 Upl Ltd Un proceso para la preparación de l-glufosinato o sales del mismo
WO2025219237A1 (en) 2024-04-15 2025-10-23 Basf Se A process for the preparation of 2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid
WO2025219236A1 (en) 2024-04-15 2025-10-23 Basf Se Process for preparing phosphorous containing diols or diol derivatives
WO2025219238A1 (en) 2024-04-15 2025-10-23 Basf Se Process for producing l-glufosinate from a diol or diol derivative

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7199E (fr) 1907-06-01 Societe Muller Et Roger Et Cie Dispositif de robinet bivalve
DE2839087A1 (de) 1978-09-08 1980-03-20 Hoechst Ag Herbizide mittel
DE3070229D1 (en) 1979-12-08 1985-03-28 Fbc Ltd Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production
FR2512015A1 (fr) 1981-08-26 1983-03-04 Dautreville & Lebas Sa Sels de l'acide 2-oxo-1,5-pentane dioique, leur procede de fabrication et medicaments renfermant ces sels
ES2058076T3 (es) 1986-06-04 1994-11-01 Hoechst Ag Procedimiento para la obtencion de l-fosfinotricina por transaminacion.
AU599985B2 (en) 1986-06-09 1990-08-02 Meiji Seika Kaisha Ltd. New process for the production of L-2-amino-4- (hydroxymethyl-phosphinyl)-butyric acid
DE3818851A1 (de) 1988-06-03 1989-12-14 Hoechst Ag Neue transaminase, ihre herstellung und ihre verwendung
ES2075056T3 (es) * 1988-10-13 1995-10-01 Fujisawa Pharmaceutical Co Oxidasa de los d-aminoacidos.
DE3842025A1 (de) 1988-12-14 1990-07-05 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin
DE3842174A1 (de) 1988-12-15 1990-06-21 Hoechst Ag Gen und genstruktur, codierend fuer eine aminotransferase, und mikroorganismen, die dieses gen exprimieren
DE3932015A1 (de) 1988-12-15 1991-04-04 Hoechst Ag Gen und genstruktur, codierend fuer eine aminotransferase, mikroorganismen, die dieses gen exprimieren, und transaminierungsverfahren unter verwendung des expressionsprodukts
DE3920570A1 (de) 1989-06-23 1991-01-03 Hoechst Ag Verfahren zur isolierung von l-2-amino-4-methylphosphinobuttersaeure-ammoniumsalz aus einer enzymatischen transaminierungsloesung
DE4030578A1 (de) * 1990-09-27 1992-04-16 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin durch eine gekoppelte enzymatische reaktion
JP3152991B2 (ja) 1991-04-27 2001-04-03 ヘキスト・アクチェンゲゼルシャフト 液状除草剤組成物
JPH06245780A (ja) 1993-02-25 1994-09-06 Meiji Seika Kaisha Ltd Ｌ−２−アミノ−４−（ヒドロキシメチルホスフィニル）−酪酸の製造法
DE4407197A1 (de) 1994-03-04 1995-09-07 Hoechst Schering Agrevo Gmbh Verfahren zur Herstellung von /L/-Homoalanin-4-yl-(methyl)phosphinsäure und deren Salze durch Racematspaltung
US5877013A (en) * 1997-07-31 1999-03-02 Food Industry Research And Development Institute Rhodosporidium D-amino acid oxidase
DE19836700A1 (de) 1998-08-13 2000-02-17 Hoechst Schering Agrevo Gmbh Herbizide Mittel für tolerante oder resistente Getreidekulturen
DE19836726A1 (de) 1998-08-13 2000-02-17 Hoechst Schering Agrevo Gmbh Herbizide Mittel für tolerante und resistente Rapskulturen
DE19919848A1 (de) 1999-04-30 2000-11-02 Aventis Cropscience Gmbh Verfahren zur Herstellung von L-Phosphinothricin durch enzymatische Transaminierung mit Aspartat
US7202070B2 (en) 2000-10-31 2007-04-10 Biocatalytics, Inc. Method for reductive amination of a ketone using a mutated enzyme
ATE497538T1 (de) * 2002-02-26 2011-02-15 Syngenta Ltd Verfahren zur selektiven herstellung männlich- oder weiblich-steriler pflanzen
GB0316190D0 (en) 2003-07-10 2003-08-13 Syngenta Ltd Improvements in or relating to organic compounds
JP4248987B2 (ja) 2003-10-01 2009-04-02 奇美電子股▲ふん▼有限公司 アレイ基板の製造方法
DE102004008445A1 (de) 2004-02-19 2005-09-08 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren aus D-Aminosäuren
CA2558273A1 (en) * 2004-03-17 2005-09-29 Basf Plant Science Gmbh Post harvest control of genetically modified crop growth employing d-amino acid compounds
DE102004026937A1 (de) 2004-06-01 2005-12-22 Bayer Cropscience Gmbh Konzentrierte wäßrige Formulierungen für den Pflanzenschutz
WO2006124606A2 (en) * 2005-05-17 2006-11-23 Rhodia Inc. Agricultural adjuvant compositions, herbicide compositions, and methods for using such compositions
EP1918375B1 (en) 2005-08-02 2015-03-11 Kaneka Corporation D-amino acid oxidase, and method for production of l-amino acid, 2-oxo acid or cyclic imine
KR100632571B1 (ko) 2005-10-07 2006-10-09 에스케이 주식회사 탄화수소 원료 혼합물로부터 접촉분해공정을 통해서 경질올레핀계 탄화수소 화합물을 증산하는 방법
US7842647B2 (en) * 2006-02-03 2010-11-30 Bayer Cropscience Lp Stable, concentrated herbicidal compositions
EP1818411A1 (en) 2006-02-13 2007-08-15 Lonza AG Process for the preparation of optically active chiral amines
JP2007240025A (ja) 2006-03-06 2007-09-20 Daikin Ind Ltd 冷凍装置
BRPI0709553A2 (pt) * 2006-03-17 2011-07-19 Basf Plant Science Gmbh métodos para gerar uma planta de soja transgênica, e uma célula ou planta de soja, sequência de nucleotìdeo heteróloga, planta ou célula da soja, parte ou semente de uma planta de soja, método para a transformação subsequente de pelo menos duas construções de dna e uma planta de soja, planta de soja, composição para seleção, regeneração, crescimento, cultivo ou manutenção de uma célula vegetal transgênica, cultura de célula, e, meio de seleção
EP1869978A1 (de) 2006-06-21 2007-12-26 Bayer CropScience AG Schaumarme Zubereitungen für den Pflanzenschutz
CN102174632A (zh) 2009-05-19 2011-09-07 重庆邮电大学 一种非天然l-氨基酸的生物催化去消旋化制备方法
WO2011104213A2 (de) * 2010-02-26 2011-09-01 Bayer Cropscience Ag Herbizide zusammensetzung enthaltend die hydrate von saflufenacil und glyphosate oder glufosinate
WO2011129820A1 (en) * 2010-04-14 2011-10-20 Strategic Enzyme Applications, Inc. Process for producing phosphinothricin employing nitrilases
US20110287933A1 (en) * 2010-05-21 2011-11-24 Bayer Cropscience Ag Herbicidal composition for tolerant or resistant oilseed rape crops
TWI561170B (en) 2010-12-21 2016-12-11 Meiji Seika Pharma Co Ltd Stabilized liquid aqueous crop protection composition
US9255115B2 (en) 2011-09-30 2016-02-09 Meiji Seika Pharma Co. Ltd. Method for producing glufosinate P free acid
CA2934681C (en) 2013-12-19 2021-03-16 Adjuvants Unlimited, LLC Solvent systems for producing pumpable formulations of high active ether sulfates
US10888095B2 (en) * 2014-02-03 2021-01-12 Upl Limited Stable herbicidal compositions
CN104529755B (zh) 2014-12-29 2016-01-06 精晶药业股份有限公司 一种从转化液中分离α-酮戊二酸的方法
EP3277822B1 (en) * 2015-04-03 2020-05-06 Temasek Life Sciences Laboratory Limited D-amino acid-inducible gene expression system for rhodosporidium and rhodotorula
US10912301B2 (en) 2015-05-11 2021-02-09 Basf Se Herbicide combinations comprising L-glufosinate and indaziflam
CN105198732A (zh) 2015-07-06 2015-12-30 山东阳成生物科技有限公司 一种从发酵液中提取α-酮戊二酸的方法
CN105198730B (zh) 2015-09-09 2017-07-28 湖州新天字味精有限公司 一种山梨酸钾的制备方法
CN105177065B (zh) 2015-09-11 2019-07-23 浙江树人大学 一种生物转化法合成α-酮戊二酸的方法
CN105218579B (zh) 2015-09-28 2017-11-07 江苏七洲绿色化工股份有限公司 一种l‑型草铵膦铵盐的合成方法
CN105567780A (zh) 2016-01-14 2016-05-11 重庆惠健生物科技有限公司 一种l-草铵膦的酶-化学催化去消旋化制备方法
CN105603015B (zh) * 2016-01-22 2018-12-11 浙江大学 一种l-草铵膦的生产方法
KR20250156185A (ko) * 2016-03-02 2025-10-31 바스프 에스이 L-글루포시네이트를 제조하는 방법
WO2018108797A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von l-glufosinat oder dessen salzen unter verwendung von ephedrin
CN108342423A (zh) 2017-01-24 2018-07-31 武汉茵茂特生物技术有限公司 L-草铵膦的生物合成制备方法
CN106916857B (zh) 2017-03-09 2019-08-27 浙江大学 一种生产l-草铵膦的方法
CN107119084B (zh) 2017-03-23 2019-12-17 浙江大学 一种利用转氨酶和乙烯合成酶生产l-草铵膦的方法
CN108660167A (zh) 2017-03-29 2018-10-16 武汉茵茂特生物技术有限公司 L-草铵膦的生物合成方法
CN106978368B (zh) 2017-03-31 2020-04-21 浙江工业大学 解鸟氨酸拉乌尔菌及其应用
CN107445986B (zh) 2017-07-13 2019-05-31 浙江大学 一种l-草铵膦盐酸盐的分离提纯方法
CN107467061A (zh) 2017-09-26 2017-12-15 安徽国星生物化学有限公司 一种l‑草铵膦水剂及其制备方法

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