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MX2019003489A - Moleculas del receptor de envolvimiento quimerico. - Google Patents

Moleculas del receptor de envolvimiento quimerico.

Info

Publication number
MX2019003489A
MX2019003489A MX2019003489A MX2019003489A MX2019003489A MX 2019003489 A MX2019003489 A MX 2019003489A MX 2019003489 A MX2019003489 A MX 2019003489A MX 2019003489 A MX2019003489 A MX 2019003489A MX 2019003489 A MX2019003489 A MX 2019003489A
Authority
MX
Mexico
Prior art keywords
receptor molecules
engulfment receptor
chimeric engulfment
molecules
chimeric
Prior art date
Application number
MX2019003489A
Other languages
English (en)
Other versions
MX389789B (es
Inventor
Mark Corey Daniel
Original Assignee
Cero Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cero Therapeutics Inc filed Critical Cero Therapeutics Inc
Publication of MX2019003489A publication Critical patent/MX2019003489A/es
Publication of MX389789B publication Critical patent/MX389789B/es

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    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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Abstract

La presente divulgación se refiere a moléculas receptoras de envolvimiento quiméricas, células hospedadoras modificadas para incluir las moléculas de envolvimiento fagocíticas y métodos para fabricar y usar tales moléculas receptoras y células modificadas.
MX2019003489A 2016-09-27 2017-09-26 Moléculas del receptor de envolvimiento quimérico. MX389789B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662400578P 2016-09-27 2016-09-27
US201762445235P 2017-01-11 2017-01-11
PCT/US2017/053553 WO2018064076A1 (en) 2016-09-27 2017-09-26 Chimeric engulfment receptor molecules

Publications (2)

Publication Number Publication Date
MX2019003489A true MX2019003489A (es) 2020-01-23
MX389789B MX389789B (es) 2025-03-20

Family

ID=61760098

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019003489A MX389789B (es) 2016-09-27 2017-09-26 Moléculas del receptor de envolvimiento quimérico.

Country Status (12)

Country Link
US (3) US20200055917A1 (es)
EP (2) EP4089116A1 (es)
JP (3) JP7730008B2 (es)
KR (1) KR20190054094A (es)
CN (1) CN110036033B (es)
AU (1) AU2017335634A1 (es)
CA (1) CA3035080A1 (es)
ES (1) ES2912269T3 (es)
IL (1) IL265606A (es)
MX (1) MX389789B (es)
RU (1) RU2019112860A (es)
WO (1) WO2018064076A1 (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170151281A1 (en) 2015-02-19 2017-06-01 Batu Biologics, Inc. Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
WO2018064076A1 (en) 2016-09-27 2018-04-05 Cero Therapeutics, Inc. Chimeric engulfment receptor molecules
KR20200100598A (ko) * 2017-09-26 2020-08-26 세로 테라퓨틱스, 인코포레이티드 키메라 포식작용 수용체 분자 및 사용 방법
GB201717974D0 (en) * 2017-10-31 2017-12-13 Univ Court Of The Univ Of Aberdeen Modified receptors
WO2019191332A1 (en) * 2018-03-28 2019-10-03 Cero Therapeutics, Inc. Chimeric engulfment receptors and uses thereof for neurodegenerative diseases
US12291557B2 (en) 2018-03-28 2025-05-06 Cero Therapeutics Holdings, Inc. Chimeric TIM4 receptors and uses thereof
MX2020010235A (es) * 2018-03-28 2020-10-28 Cero Therapeutics Inc Vectores de expresion para receptores de engullimiento quimerico, celulas hospederas geneticamente modificadas y usos de los mismos.
WO2019191340A1 (en) * 2018-03-28 2019-10-03 Cero Therapeutics, Inc. Cellular immunotherapy compositions and uses thereof
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