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MX2018006063A - Medios y metodos de fermentacion para producir polisacarido en cultivo celular bacteriano. - Google Patents

Medios y metodos de fermentacion para producir polisacarido en cultivo celular bacteriano.

Info

Publication number
MX2018006063A
MX2018006063A MX2018006063A MX2018006063A MX2018006063A MX 2018006063 A MX2018006063 A MX 2018006063A MX 2018006063 A MX2018006063 A MX 2018006063A MX 2018006063 A MX2018006063 A MX 2018006063A MX 2018006063 A MX2018006063 A MX 2018006063A
Authority
MX
Mexico
Prior art keywords
media
fermentation methods
relates
cell culture
bacterial cell
Prior art date
Application number
MX2018006063A
Other languages
English (en)
Other versions
MX385736B (es
Inventor
Gururao Desai Sunil
Allen Hanson Michael
Patrick Kinross Jonathan
R Lasko Daniel
Ellis LOMBERK Scott
Arnold Lotvin Jason
Kaushikbhai PATEL-BROWN Sujata
Sun Weiqiang
Anthony Tomasello Peter
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX2018006063A publication Critical patent/MX2018006063A/es
Publication of MX385736B publication Critical patent/MX385736B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a medios y métodos de fermentación para producir polisacáridos en cultivo celular bacteriano. En un aspecto, la invención se refiere a un medio de cultivo complejo que comprende un hidrolisato vegetal , un extracto de levadura y una fuente de carbono. En otro aspecto, la invención se refiere a un medio definido que tiene una concentración total de aminoácido mayor de aproximadamente 50 mM. Otro aspecto de la invención se refiere al uso de métodos de lotes alimentados y fermentación por perfusión para cultivar bacteria que produce polisacárido.
MX2018006063A 2015-11-17 2016-11-10 Medios y métodos de fermentación para producir polisacárido en cultivo celular bacteriano. MX385736B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562256347P 2015-11-17 2015-11-17
US201662413051P 2016-10-26 2016-10-26
PCT/IB2016/056780 WO2017085602A1 (en) 2015-11-17 2016-11-10 Media and fermentation methods for producing polysaccharides in bacterial cell culture

Publications (2)

Publication Number Publication Date
MX2018006063A true MX2018006063A (es) 2018-09-17
MX385736B MX385736B (es) 2025-03-18

Family

ID=57394621

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018006063A MX385736B (es) 2015-11-17 2016-11-10 Medios y métodos de fermentación para producir polisacárido en cultivo celular bacteriano.
MX2021010518A MX2021010518A (es) 2015-11-17 2018-05-16 Medios y metodos de fermentacion para producir polisacarido en cultivo celular bacteriano.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021010518A MX2021010518A (es) 2015-11-17 2018-05-16 Medios y metodos de fermentacion para producir polisacarido en cultivo celular bacteriano.

Country Status (13)

Country Link
US (3) US10947494B2 (es)
EP (1) EP3377613A1 (es)
JP (3) JP7311966B2 (es)
KR (1) KR102069988B1 (es)
CN (1) CN108473945A (es)
AU (1) AU2016357567B2 (es)
BR (1) BR112018008864A8 (es)
CA (2) CA3005308C (es)
HK (1) HK1259103A1 (es)
IL (2) IL319202A (es)
MX (2) MX385736B (es)
RU (2) RU2761633C2 (es)
WO (1) WO2017085602A1 (es)

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BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
HRP20240433T1 (hr) 2016-09-02 2024-07-05 Sanofi Pasteur, Inc. Cjepivo protiv neisseria meningitidis
KR20240169144A (ko) 2017-01-31 2024-12-02 머크 샤프 앤드 돔 엘엘씨 다당류-단백질 접합체 제조 방법
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MX394767B (es) 2017-09-07 2025-03-24 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina transportadora.
CN116898959A (zh) 2017-09-07 2023-10-20 默沙东有限责任公司 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途
AU2018400751B2 (en) 2017-12-06 2022-07-21 Merck Sharp & Dohme Llc Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
JP7397000B2 (ja) 2018-04-30 2023-12-12 メルク・シャープ・アンド・ドーム・エルエルシー 凍結乾燥変異ジフテリア毒素のジメチルスルホキシド中均一溶液を提供する方法
JP7506605B6 (ja) 2018-04-30 2024-07-16 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎球菌莢膜多糖類担体タンパク質複合体の製造方法
CN112074294B (zh) 2018-04-30 2025-07-11 默沙东有限责任公司 从冻干球生产肺炎链球菌荚膜多糖载体蛋白缀合物的方法
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CA3122085A1 (en) * 2018-12-11 2020-06-18 Erbi Biosystems, Inc. Methods of manufacturing cell based products using small volume perfusion processes
GEAP202415690A (en) 2018-12-19 2024-01-10 Merck Sharp & Dohme Llc Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
CN111254103B (zh) * 2019-11-19 2023-06-02 河南省生物工程技术研究中心 一种非洲猪瘟基因工程疫苗高密度发酵补料培养基及发酵工艺
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CN114181872B (zh) * 2022-01-07 2023-11-24 北京大北农科技集团股份有限公司 一种屎肠球菌高密度发酵培养方法
KR102864280B1 (ko) * 2022-12-27 2025-09-26 (주)진성유니텍 포도상구균 증균을 위한 최소배지 및 이를 이용한 포도상구균 증균방법
KR102866798B1 (ko) * 2022-12-27 2025-10-01 (주)진성유니텍 살모넬라균 증균을 위한 최소배지 및 이를 이용한 살모넬라균 증균방법
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Also Published As

Publication number Publication date
BR112018008864A8 (pt) 2019-02-26
RU2021135165A (ru) 2021-12-29
JP7311966B2 (ja) 2023-07-20
CN108473945A (zh) 2018-08-31
IL259404A (en) 2018-07-31
IL259404B2 (en) 2025-08-01
IL319202A (en) 2025-04-01
CA3005308A1 (en) 2017-05-26
US10947494B2 (en) 2021-03-16
US20260008994A1 (en) 2026-01-08
RU2018118035A3 (es) 2019-12-18
KR20180073699A (ko) 2018-07-02
RU2761633C2 (ru) 2021-12-13
AU2016357567A1 (en) 2018-05-17
BR112018008864A2 (pt) 2018-11-06
RU2018118035A (ru) 2019-12-18
KR102069988B1 (ko) 2020-01-23
IL259404B1 (en) 2025-04-01
US20190292513A1 (en) 2019-09-26
AU2016357567B2 (en) 2020-05-07
JP2022017529A (ja) 2022-01-25
WO2017085602A1 (en) 2017-05-26
US20210180008A1 (en) 2021-06-17
MX2021010518A (es) 2021-10-01
EP3377613A1 (en) 2018-09-26
JP2018533366A (ja) 2018-11-15
JP2024037949A (ja) 2024-03-19
MX385736B (es) 2025-03-18
HK1259103A1 (zh) 2019-11-22
CA3138763A1 (en) 2017-05-26
CA3005308C (en) 2022-01-04

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