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MX2018002795A - Preparacion de acido alginico secada por congelacion. - Google Patents

Preparacion de acido alginico secada por congelacion.

Info

Publication number
MX2018002795A
MX2018002795A MX2018002795A MX2018002795A MX2018002795A MX 2018002795 A MX2018002795 A MX 2018002795A MX 2018002795 A MX2018002795 A MX 2018002795A MX 2018002795 A MX2018002795 A MX 2018002795A MX 2018002795 A MX2018002795 A MX 2018002795A
Authority
MX
Mexico
Prior art keywords
freeze
alginic acid
dried
monovalent metal
metal salt
Prior art date
Application number
MX2018002795A
Other languages
English (en)
Inventor
Endo Shuichi
YOSHIOKA Naoya
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of MX2018002795A publication Critical patent/MX2018002795A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

La presente invención proporciona: una composición secada por congelación que comprende (a) un alginato de metal monovalente y (b) una sal seleccionada de una sal de metal monovalente y una sal de amonio; y un método para producir una composición de alginato de metal monovalente secada por congelación que comprende las etapas de congelar una solución acuosa formada al disolver por lo menos el componente (a) y el componente (b), realizar el primer secado, y luego realizar el segundo secado como sea deseado para reducir un contenido de agua a 3% en masa o menos. Esta es una composición de alginato de metal monovalente secada por congelación con disminución de viscosidad suprimida con el transcurso de tiempo.
MX2018002795A 2015-09-07 2016-09-06 Preparacion de acido alginico secada por congelacion. MX2018002795A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015175583 2015-09-07
PCT/JP2016/076176 WO2017043485A1 (ja) 2015-09-07 2016-09-06 アルギン酸凍結乾燥製剤

Publications (1)

Publication Number Publication Date
MX2018002795A true MX2018002795A (es) 2018-04-24

Family

ID=58239809

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018002795A MX2018002795A (es) 2015-09-07 2016-09-06 Preparacion de acido alginico secada por congelacion.

Country Status (12)

Country Link
US (3) US10966929B2 (es)
EP (1) EP3348271B1 (es)
JP (2) JP7020913B2 (es)
KR (1) KR102740598B1 (es)
CN (2) CN113274360A (es)
AU (1) AU2016319444B2 (es)
CA (1) CA2997684A1 (es)
ES (1) ES2991647T3 (es)
IL (1) IL257884A (es)
MX (1) MX2018002795A (es)
RU (1) RU2018112431A (es)
WO (1) WO2017043485A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2801355T3 (pl) * 2004-10-08 2015-10-30 Fwp Ip Aps Kompozycje farmaceutycznie o kontrolowanym uwalnianiu zawierające ester kwasu fumarowego
KR102740598B1 (ko) 2015-09-07 2024-12-09 모찌다 세이야쿠 가부시끼가이샤 알긴산 동결 건조 제제
WO2017163603A1 (ja) * 2016-03-23 2017-09-28 国立大学法人北海道大学 椎間板治療用組成物
WO2018164128A1 (ja) * 2017-03-07 2018-09-13 持田製薬株式会社 アルギン酸液剤
JP7295032B2 (ja) * 2017-05-02 2023-06-20 マサチューセッツ インスティテュート オブ テクノロジー 凍結乾燥方法および関連製品
CN118831199B (zh) * 2024-06-26 2025-02-11 北京冠合医疗科技有限公司 一种海藻酸钠栓塞颗粒及其制备方法与应用

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FR2592383B1 (fr) 1985-12-26 1990-01-19 Adeline Andre Procede de preparation d'un film souple d'alginate de calcium
JPH06343479A (ja) * 1993-06-04 1994-12-20 Usuki Seiyaku Kk 増粘剤およびその用途
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JP2005145885A (ja) * 2003-11-14 2005-06-09 Japan Science & Technology Agency アルギン酸オリゴマーからなる免疫機構賦活剤
CN101209344B (zh) * 2006-12-28 2012-07-04 赵超英 高渗液组合物在制备促进伤口愈合的药物中的应用
CN104906126B (zh) * 2007-02-21 2019-05-28 持田制药株式会社 用于治疗软骨疾病的组合物
US20090208492A1 (en) 2007-06-14 2009-08-20 Elan Pharmaceuticals, Inc. Lyophilized Immunoglobulin Formulations and Methods of Preparation
AU2008296975B2 (en) * 2007-08-28 2014-07-24 Fmc Corporation Delayed self-gelling alginate systems and uses thereof
AU2008315175B2 (en) * 2007-10-24 2013-12-12 Mochida Pharmaceutical Co., Ltd. Composition for treatment of joint disease
CN101260160A (zh) * 2008-04-23 2008-09-10 海南大学 一种部分氧化海藻酸钠的方法
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KR102740598B1 (ko) 2015-09-07 2024-12-09 모찌다 세이야쿠 가부시끼가이샤 알긴산 동결 건조 제제

Also Published As

Publication number Publication date
CA2997684A1 (en) 2017-03-16
KR102740598B1 (ko) 2024-12-09
WO2017043485A1 (ja) 2017-03-16
US12151025B2 (en) 2024-11-26
EP3348271A1 (en) 2018-07-18
US20210186882A1 (en) 2021-06-24
RU2018112431A3 (es) 2020-02-13
JP7367089B2 (ja) 2023-10-23
JP2022048356A (ja) 2022-03-25
US20180338921A1 (en) 2018-11-29
CN108135928A (zh) 2018-06-08
US10966929B2 (en) 2021-04-06
KR20180040158A (ko) 2018-04-19
IL257884A (en) 2018-05-31
EP3348271A4 (en) 2018-08-22
CN108135928B (zh) 2021-06-08
AU2016319444B2 (en) 2022-05-12
CN113274360A (zh) 2021-08-20
US20230210777A1 (en) 2023-07-06
ES2991647T3 (es) 2024-12-04
RU2018112431A (ru) 2019-10-09
AU2016319444A1 (en) 2018-04-19
EP3348271B1 (en) 2024-09-04
JPWO2017043485A1 (ja) 2018-08-16
JP7020913B2 (ja) 2022-02-16

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