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MX2017013080A - Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r). - Google Patents

Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r).

Info

Publication number
MX2017013080A
MX2017013080A MX2017013080A MX2017013080A MX2017013080A MX 2017013080 A MX2017013080 A MX 2017013080A MX 2017013080 A MX2017013080 A MX 2017013080A MX 2017013080 A MX2017013080 A MX 2017013080A MX 2017013080 A MX2017013080 A MX 2017013080A
Authority
MX
Mexico
Prior art keywords
chain polypeptide
interleucine
receiver
antibodies against
directed antibodies
Prior art date
Application number
MX2017013080A
Other languages
English (en)
Inventor
J King David
John Mcknight Andrew
Bowers Peter
Londei Marco
Original Assignee
Anaptysbio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anaptysbio Inc filed Critical Anaptysbio Inc
Publication of MX2017013080A publication Critical patent/MX2017013080A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Transplantation (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La invención se refiere a un polipeptido de cadena pesada de inmunoglobulina aislado y un polipeptido de cadena ligera de inmunoglobulina aislado que enlaza a una proteína codificada por el receptor de interleucina 36 (IL-36R). La invención proporciona un agente de enlace IL-36R que comprende el polipeptido de cadena pesada de inmunoglobulina y el polipeptido de cadena ligera de inmunoglobulina antes mencionados. La invención también proporciona vectores relacionados, composiciones, y métodos para usar el agente de enlace IL-36R para tratar un trastorno o enfermedad que es sensible a la inhibición de IL-36R, tal como cáncer, una enfermedad infecciosa, o una enfermedad autoinmunitaria.
MX2017013080A 2015-04-15 2016-04-15 Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r). MX2017013080A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562147824P 2015-04-15 2015-04-15
PCT/US2016/027676 WO2016168542A1 (en) 2015-04-15 2016-04-15 Antibodies directed against interleukin 36 receptor (il-36r)

Publications (1)

Publication Number Publication Date
MX2017013080A true MX2017013080A (es) 2018-02-09

Family

ID=57126337

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017013080A MX2017013080A (es) 2015-04-15 2016-04-15 Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r).
MX2023001791A MX2023001791A (es) 2015-04-15 2017-10-11 Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r).

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023001791A MX2023001791A (es) 2015-04-15 2017-10-11 Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r).

Country Status (14)

Country Link
US (4) US10526410B2 (es)
EP (2) EP4176900A1 (es)
JP (4) JP6913026B2 (es)
KR (1) KR102666920B1 (es)
CN (2) CN115925932A (es)
AU (1) AU2016248208B2 (es)
CA (1) CA2982555A1 (es)
DK (1) DK3283110T3 (es)
ES (1) ES2914243T3 (es)
MX (2) MX2017013080A (es)
PL (1) PL3283110T3 (es)
RU (1) RU2745898C2 (es)
SG (1) SG11201708061TA (es)
WO (1) WO2016168542A1 (es)

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WO2022026829A1 (en) 2020-07-30 2022-02-03 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for skin toxicity
CN112094349B (zh) * 2020-11-04 2021-02-09 上海华奥泰生物药业股份有限公司 靶向于白介素36r的抗体及其制备方法和应用
WO2022150642A1 (en) 2021-01-08 2022-07-14 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for hidradenitis suppurativa
WO2022150644A1 (en) 2021-01-08 2022-07-14 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for acne
KR20230154455A (ko) * 2021-03-04 2023-11-08 베링거 인겔하임 인터내셔날 게엠베하 Gpp의 치료를 위한 방법
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Also Published As

Publication number Publication date
RU2745898C2 (ru) 2021-04-02
US20260022181A1 (en) 2026-01-22
HK1250941A1 (en) 2019-01-18
US20210388095A1 (en) 2021-12-16
AU2016248208B2 (en) 2022-03-24
JP2023040236A (ja) 2023-03-22
HK1252009A1 (zh) 2019-05-10
BR112017022086A2 (pt) 2018-07-03
WO2016168542A1 (en) 2016-10-20
CN107847590A (zh) 2018-03-27
AU2016248208A1 (en) 2017-11-09
JP6913026B2 (ja) 2021-08-04
EP3283110A1 (en) 2018-02-21
NZ736535A (en) 2024-08-30
RU2017139481A (ru) 2019-05-15
PL3283110T3 (pl) 2022-06-27
KR102666920B1 (ko) 2024-05-20
ES2914243T3 (es) 2022-06-08
RU2017139481A3 (es) 2019-09-19
CN107847590B (zh) 2022-07-26
EP4176900A1 (en) 2023-05-10
US12391761B2 (en) 2025-08-19
EP3283110B1 (en) 2022-04-20
KR20180002687A (ko) 2018-01-08
EP3283110A4 (en) 2019-02-27
US11130814B2 (en) 2021-09-28
JP7212098B2 (ja) 2023-01-24
JP7721585B2 (ja) 2025-08-12
JP2021118710A (ja) 2021-08-12
JP2018512157A (ja) 2018-05-17
MX2023001791A (es) 2023-03-10
US20200087408A1 (en) 2020-03-19
US10526410B2 (en) 2020-01-07
DK3283110T3 (da) 2022-05-23
JP2025163120A (ja) 2025-10-28
SG11201708061TA (en) 2017-10-30
CN115925932A (zh) 2023-04-07
CA2982555A1 (en) 2016-10-20
US20180094065A1 (en) 2018-04-05

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