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MX2018009218A - Anticuerpos de cgrp y sus usos. - Google Patents

Anticuerpos de cgrp y sus usos.

Info

Publication number
MX2018009218A
MX2018009218A MX2018009218A MX2018009218A MX2018009218A MX 2018009218 A MX2018009218 A MX 2018009218A MX 2018009218 A MX2018009218 A MX 2018009218A MX 2018009218 A MX2018009218 A MX 2018009218A MX 2018009218 A MX2018009218 A MX 2018009218A
Authority
MX
Mexico
Prior art keywords
cgrp
cgrp antibodies
antibodies
human
kits
Prior art date
Application number
MX2018009218A
Other languages
English (en)
Inventor
Allan Barrett
Chai Xiyun
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2018009218A publication Critical patent/MX2018009218A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/585Calcitonins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2842Pain, e.g. neuropathic pain, psychogenic pain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se relaciona con anticuerpos que se unen a CGRP humano, composiciones y kits que comprenden tales anticuerpos CGRP y métodos para usar tales anticuerpos CGRP para la detección de CGRP humano.
MX2018009218A 2016-01-28 2017-01-20 Anticuerpos de cgrp y sus usos. MX2018009218A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662288045P 2016-01-28 2016-01-28
PCT/US2017/014325 WO2017132062A1 (en) 2016-01-28 2017-01-20 Cgrp antibodies and uses thereof

Publications (1)

Publication Number Publication Date
MX2018009218A true MX2018009218A (es) 2018-11-09

Family

ID=57910192

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018009218A MX2018009218A (es) 2016-01-28 2017-01-20 Anticuerpos de cgrp y sus usos.

Country Status (11)

Country Link
US (1) US20190031748A1 (es)
EP (1) EP3408290A1 (es)
JP (1) JP2019501152A (es)
KR (1) KR20180091930A (es)
CN (1) CN108473567A (es)
AU (1) AU2017211043A1 (es)
BR (1) BR112018010596A2 (es)
CA (1) CA3007018A1 (es)
EA (1) EA201891196A1 (es)
MX (1) MX2018009218A (es)
WO (1) WO2017132062A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202102758RA (en) * 2018-09-20 2021-04-29 Teva Pharmaceuticals Int Gmbh Injection spring for aged prefilled syringe and auto injector
WO2020239014A1 (zh) * 2019-05-30 2020-12-03 山东博安生物技术有限公司 抗cgrp抗体及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007054809A2 (en) * 2005-11-14 2007-05-18 Rinat Neuroscience Corp. Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
WO2007076336A1 (en) * 2005-12-22 2007-07-05 Eli Lilly And Company Treatment of migraine with anti-cgrp antibodies
EP2265287B1 (en) * 2008-03-04 2018-09-05 Teva Pharmaceuticals International GmbH Methods of treating chronic pain
ES2584907T3 (es) 2008-03-04 2016-09-30 Labrys Biologics Inc. Métodos para tratamiento del dolor inflamatorio
JO3330B1 (ar) * 2010-06-10 2019-03-13 Lilly Co Eli الأجسام المضادة cgrp
EP3662932B1 (en) * 2011-05-20 2021-04-07 H. Lundbeck A/S Anti-cgrp compositions and use thereof

Also Published As

Publication number Publication date
AU2017211043A1 (en) 2018-06-14
EP3408290A1 (en) 2018-12-05
JP2019501152A (ja) 2019-01-17
BR112018010596A2 (pt) 2018-11-13
KR20180091930A (ko) 2018-08-16
WO2017132062A1 (en) 2017-08-03
US20190031748A1 (en) 2019-01-31
CA3007018A1 (en) 2017-08-03
EA201891196A1 (ru) 2018-12-28
CN108473567A (zh) 2018-08-31

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