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MX2017008198A - Composicion del medio para preparar toxina botulinica. - Google Patents

Composicion del medio para preparar toxina botulinica.

Info

Publication number
MX2017008198A
MX2017008198A MX2017008198A MX2017008198A MX2017008198A MX 2017008198 A MX2017008198 A MX 2017008198A MX 2017008198 A MX2017008198 A MX 2017008198A MX 2017008198 A MX2017008198 A MX 2017008198A MX 2017008198 A MX2017008198 A MX 2017008198A
Authority
MX
Mexico
Prior art keywords
medium
botulinum toxin
present
medium composition
plant
Prior art date
Application number
MX2017008198A
Other languages
English (en)
Inventor
Yun KIM Kyoung-
Young Sul Hye-
Min MIN Kyoung-
Original Assignee
Daewoong Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daewoong Co Ltd filed Critical Daewoong Co Ltd
Publication of MX2017008198A publication Critical patent/MX2017008198A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a una composición del medio para la producción de toxina botulínica y, más particularmente, a una composición del medio para el cultivo de Clostridium sp. capaz de producir toxina botulínica. La composición del medio de la presente invención comprende una peptona porcina y al menos una peptona derivada de plantas seleccionada del grupo que consiste de un hidrolizado de guisantes, un hidrolizado de semillas de algodón y un hidrolizado de gluten de trigo. Cuando el medio de acuerdo a la presente invención, que contiene peptonas derivadas de plantas y minerales, se utiliza para el cultivo de Clostridium botulinum, la velocidad de crecimiento de la bacteria en el medio es mayor que el de cada uno del medio que está en uso actual y el medio que comprende solo peptonas derivadas de plantas. Además, cuando el medio de la presente invención se utiliza, se puede producir una alta concentración de toxina botulínica cultivando la bacteria de forma segura.
MX2017008198A 2015-04-28 2016-04-28 Composicion del medio para preparar toxina botulinica. MX2017008198A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020150059656A KR101723168B1 (ko) 2015-04-28 2015-04-28 보툴리눔 독소의 제조를 위한 배지 조성물
PCT/KR2016/004432 WO2016175567A1 (en) 2015-04-28 2016-04-28 Medium composition for preparing botulinum toxin

Publications (1)

Publication Number Publication Date
MX2017008198A true MX2017008198A (es) 2017-09-13

Family

ID=57199572

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008198A MX2017008198A (es) 2015-04-28 2016-04-28 Composicion del medio para preparar toxina botulinica.

Country Status (13)

Country Link
US (1) US10308923B2 (es)
EP (1) EP3289071A4 (es)
JP (2) JP2018500881A (es)
KR (1) KR101723168B1 (es)
CN (1) CN107002026A (es)
AR (1) AR104418A1 (es)
AU (1) AU2016253790B2 (es)
BR (1) BR112017012893A2 (es)
CA (1) CA2968050A1 (es)
MX (1) MX2017008198A (es)
RU (1) RU2679836C2 (es)
TW (1) TWI592486B (es)
WO (1) WO2016175567A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101723167B1 (ko) * 2015-04-28 2017-04-05 주식회사 대웅 보툴리눔 독소의 제조를 위한 배지 조성물
KR101723168B1 (ko) * 2015-04-28 2017-04-05 주식회사 대웅 보툴리눔 독소의 제조를 위한 배지 조성물
KR20250065972A (ko) * 2023-11-06 2025-05-13 주식회사 대웅 보툴리눔 독소의 제조를 위한 배지 조성물

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558926B1 (en) 1999-07-16 2003-05-06 Massachusetts Institute Of Technology Method for production of tetanus toxin using media substantially free of animal products
US7160699B2 (en) 2003-09-25 2007-01-09 Allergan, Inc. Media for clostridium bacterium and processes for obtaining a clostridial toxin
US7148041B2 (en) * 2003-09-25 2006-12-12 Allergan, Inc. Animal product free media and processes for obtaining a botulinum toxin
RU2255761C1 (ru) 2004-07-01 2005-07-10 Общество с ограниченной ответственностью "Токсины и сопутствующие продукты" Препарат для лечения мышечных дистоний из токсина культуры clostridium botulinum и способ его получения
WO2006042542A2 (en) * 2004-10-19 2006-04-27 Statens Serum Institut Production of tetanus, diphtheria, and pertussis toxins and toxoids using fermentation media containing no components of animal or soy origin
MXPA06009853A (es) * 2005-03-03 2007-03-29 Allergan Inc Medios para bacteria de clostridium y procesos para obtener una toxina clostridial.
CA2850858A1 (en) * 2005-09-16 2007-04-05 Allergan, Inc. Compositions and methods for the intraocular transport of therapeutic agents
KR100680318B1 (ko) * 2005-12-16 2007-02-08 최성현 미생물 배양용 영양배지
US7811560B2 (en) * 2006-01-30 2010-10-12 Auxilium Us Holdings, Llc Compositions and methods for treating collagen-mediated diseases
FR2918671B1 (fr) * 2007-07-10 2010-10-15 Sanofi Pasteur Milieu de culture d'haemophilus influenzae type b.
KR20090120222A (ko) * 2008-05-19 2009-11-24 (주)메디톡스 식물 유래 성분 함유 배지 및 가요성 폐쇄 용기를 이용하여클로스트리디움 보툴리눔 독소를 생산하는 방법
US8236356B2 (en) 2008-06-11 2012-08-07 Roche Diagnostics Operations, Inc. Growth medium for Clostridium histolyticum
KR101339349B1 (ko) * 2013-08-02 2013-12-09 주식회사 대웅 보툴리눔 독소의 제조방법
KR101729251B1 (ko) * 2015-04-28 2017-04-21 주식회사 대웅 보툴리눔 독소의 제조를 위한 배지 조성물
KR101723168B1 (ko) * 2015-04-28 2017-04-05 주식회사 대웅 보툴리눔 독소의 제조를 위한 배지 조성물
KR101723167B1 (ko) * 2015-04-28 2017-04-05 주식회사 대웅 보툴리눔 독소의 제조를 위한 배지 조성물
KR101775682B1 (ko) * 2015-11-30 2017-09-06 주식회사 대웅 보툴리눔 독소의 제조방법

Also Published As

Publication number Publication date
AU2016253790A1 (en) 2017-05-25
RU2017120815A3 (es) 2018-12-14
KR101723168B1 (ko) 2017-04-05
BR112017012893A2 (pt) 2018-01-30
KR20160127999A (ko) 2016-11-07
TW201638330A (zh) 2016-11-01
JP2020022436A (ja) 2020-02-13
US20170260515A1 (en) 2017-09-14
AR104418A1 (es) 2017-07-19
TWI592486B (zh) 2017-07-21
US10308923B2 (en) 2019-06-04
EP3289071A4 (en) 2018-10-31
EP3289071A1 (en) 2018-03-07
JP2018500881A (ja) 2018-01-18
CN107002026A (zh) 2017-08-01
CA2968050A1 (en) 2016-11-03
RU2679836C2 (ru) 2019-02-13
RU2017120815A (ru) 2018-12-14
AU2016253790B2 (en) 2018-11-29
WO2016175567A1 (en) 2016-11-03

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