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MX2017001008A - Tratamiento de cancer utilizando un receptor quimerico de antigeno cd33. - Google Patents

Tratamiento de cancer utilizando un receptor quimerico de antigeno cd33.

Info

Publication number
MX2017001008A
MX2017001008A MX2017001008A MX2017001008A MX2017001008A MX 2017001008 A MX2017001008 A MX 2017001008A MX 2017001008 A MX2017001008 A MX 2017001008A MX 2017001008 A MX2017001008 A MX 2017001008A MX 2017001008 A MX2017001008 A MX 2017001008A
Authority
MX
Mexico
Prior art keywords
ancient
cancer treatment
car
chemical receiver
receiver
Prior art date
Application number
MX2017001008A
Other languages
English (en)
Other versions
MX390943B (es
Inventor
Huber Thomas
Murphy Leon
Singh Reshma
Brogdon Jennifer
Glass David
Mannick Joan
Song Huijuan
Gill Saar
Kenderian Saad
Ebersbach Hilmar
Jascur Julia
C Milone Michael
Richardson Celeste
Wu Qilong
Zhang Jiquan
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2017001008A publication Critical patent/MX2017001008A/es
Publication of MX390943B publication Critical patent/MX390943B/es

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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Abstract

La invención proporciona composiciones y métodos para el tratamiento de enfermedades asociadas con la expresión de CD33. La invención se refiere también a receptor quimérico antígeno (CAR) específico para CD33, los vectores que codifica el mismo, y las células T recombinantes que comprenden el CAR CD33. La invención también incluye métodos de administración de una célula T modificado genéticamente que expresa un CAR que comprende un dominio de unión a CD33.
MX2017001008A 2014-07-21 2015-07-21 Receptores de antígeno quimérico cd33 y usos de los mismos. MX390943B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2014082589 2014-07-21
CN2014090504 2014-11-06
PCT/US2015/041390 WO2016014576A1 (en) 2014-07-21 2015-07-21 Treatment of cancer using a cd33 chimeric antigen receptor

Publications (2)

Publication Number Publication Date
MX2017001008A true MX2017001008A (es) 2017-08-02
MX390943B MX390943B (es) 2025-03-21

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MX2017001008A MX390943B (es) 2014-07-21 2015-07-21 Receptores de antígeno quimérico cd33 y usos de los mismos.

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US (4) US9777061B2 (es)
EP (2) EP3172234B1 (es)
JP (2) JP6831777B2 (es)
KR (1) KR102594343B1 (es)
CN (2) CN112481283A (es)
AU (2) AU2015292755B2 (es)
BR (1) BR112017001242A2 (es)
CA (1) CA2955154C (es)
CO (1) CO2017000510A2 (es)
ES (1) ES2805475T3 (es)
IL (1) IL250138B (es)
MX (1) MX390943B (es)
RU (1) RU2747384C2 (es)
SG (2) SG11201700416TA (es)
TW (1) TWI719942B (es)
WO (1) WO2016014576A1 (es)
ZA (1) ZA201700157B (es)

Families Citing this family (204)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2014010185A (es) 2012-02-22 2014-11-14 Univ Pennsylvania Uso de dominio de señalizacion cd2 en receptores de antigeno quimericos de segunda generacion.
EP3653212B1 (en) 2012-12-20 2023-04-26 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
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