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MX2016012799A - Metodos para tratar el virus de la hepatitis c. - Google Patents

Metodos para tratar el virus de la hepatitis c.

Info

Publication number
MX2016012799A
MX2016012799A MX2016012799A MX2016012799A MX2016012799A MX 2016012799 A MX2016012799 A MX 2016012799A MX 2016012799 A MX2016012799 A MX 2016012799A MX 2016012799 A MX2016012799 A MX 2016012799A MX 2016012799 A MX2016012799 A MX 2016012799A
Authority
MX
Mexico
Prior art keywords
treatment
virus
methods
weeks
compound
Prior art date
Application number
MX2016012799A
Other languages
English (en)
Other versions
MX388482B (es
Inventor
M Bernstein Barry
J Podsadecki Thomas
Dutta Sandeep
Lin Chih-Wei
Wang Tianli
Liu Wei
L Campbell Andrew
M Menon Rajeev
M Awni Walid
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52829479&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016012799(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MX2016012799A publication Critical patent/MX2016012799A/es
Publication of MX388482B publication Critical patent/MX388482B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención caracteriza terapias libres de interferón para el tratamiento del VHC. Preferiblemente, el tratamiento es sobre una duración más corta de tratamiento, tal como no más de 12 semanas. En un aspecto, el tratamiento comprende administrar al menos dos agentes antivíricos de acción directa a un sujeto con la infección del VRC, en donde el tratamiento tiene una duración de 12 semanas y no incluye administración de ya sea interferón o ribavirina, y al menos los dos agentes antiviricos de acción directa comprenden (a) Compuesto 1 o una sal farmacéuticamente aceptable del mismo y (b) Compuesto 2 o una sal farmacéuticamente aceptable del mismo.
MX2016012799A 2014-04-02 2015-04-01 Métodos para tratar el virus de la hepatitis c. MX388482B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201461973929P 2014-04-02 2014-04-02
US201461989951P 2014-05-07 2014-05-07
US201462016459P 2014-06-24 2014-06-24
PCT/US2015/023923 WO2015153793A1 (en) 2014-04-02 2015-04-01 Methods for treating hcv

Publications (2)

Publication Number Publication Date
MX2016012799A true MX2016012799A (es) 2016-12-12
MX388482B MX388482B (es) 2025-03-20

Family

ID=52829479

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016012799A MX388482B (es) 2014-04-02 2015-04-01 Métodos para tratar el virus de la hepatitis c.

Country Status (9)

Country Link
US (2) US10286029B2 (es)
EP (1) EP3125889A1 (es)
JP (2) JP6632992B2 (es)
CN (4) CN110302361A (es)
AU (3) AU2015240754B2 (es)
BR (1) BR112016022976A8 (es)
CA (1) CA2942823C (es)
MX (1) MX388482B (es)
WO (1) WO2015153793A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200368229A9 (en) * 2013-03-14 2020-11-26 Abbvie Inc. Methods for Treating HCV
CN106456621A (zh) * 2013-03-14 2017-02-22 艾伯维公司 用于治疗hcv的方法
US11484534B2 (en) 2013-03-14 2022-11-01 Abbvie Inc. Methods for treating HCV
US20180042982A1 (en) * 2013-03-14 2018-02-15 Abbvie Inc. Methods for Treating HCV
CN110302361A (zh) 2014-04-02 2019-10-08 艾伯维公司 治疗hcv的方法
US20160375017A1 (en) 2015-06-26 2016-12-29 Abbvie Inc. Solid Pharmaceutical Compositions for Treating HCV
US20180177779A1 (en) * 2015-07-08 2018-06-28 Abbvie Inc. Methods for Treating HCV
MA46292A (fr) * 2016-09-23 2019-07-31 Abbvie Inc Réglage de dose
JP2018131439A (ja) * 2017-02-14 2018-08-23 アッヴィ・インコーポレイテッド Ｈｃｖを処置する方法
CA2981993A1 (en) * 2017-08-02 2019-02-02 Abbvie Inc. Methods for treating hcv
AU2019384793A1 (en) 2018-11-20 2021-06-10 Abbvie Inc. Methods for treating acute HCV
JP6734610B1 (ja) 2020-03-31 2020-08-05 株式会社ビードットメディカル 超電導電磁石装置及び荷電粒子ビーム照射装置
JP6807125B1 (ja) 2020-06-17 2021-01-06 株式会社ビードットメディカル 荷電粒子ビーム照射装置

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US3466159A (en) 1965-03-26 1969-09-09 Chemical Construction Corp Process and catalyst for production of methane-rich gas
US3492386A (en) 1967-06-06 1970-01-27 Okura Industrial Co Ltd Extending process and device for tubular films of thermoplastic synthetic resin
US3685984A (en) 1970-09-04 1972-08-22 Dow Chemical Co Removing metal carbides from furnace systems
US3648037A (en) 1970-12-31 1972-03-07 Gen Electric Symmetrical function generator
BE791313A (fr) 1971-12-13 1973-05-14 Baker Perkins Inc Appareillage de demoulage, notamment pour produits de boulangerie
US3853176A (en) 1973-03-01 1974-12-10 Bergeson Caswell Inc Well cleaning apparatus
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AU2003900553A0 (en) * 2003-02-10 2003-02-20 Borody, Thomas Julius Novel Improved Method for Detection of Dientamoeba fragilis and other Parasites
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NZ608720A (en) * 2010-09-21 2015-03-27 Enanta Pharm Inc Macrocyclic proline derived hcv serine protease inhibitors
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MX2015003492A (es) * 2012-09-18 2015-06-04 Abbvie Inc Metodos para el tratamiento de la hepatitis c.
LT2897611T (lt) 2012-09-18 2019-12-10 Abbvie Inc Hepatito c gydymo būdai
WO2014099908A1 (en) 2012-12-17 2014-06-26 Genentech, Inc. Methods for inhibiting viral infection in transplant patients
CN106456621A (zh) 2013-03-14 2017-02-22 艾伯维公司 用于治疗hcv的方法
RS60881B1 (sr) * 2013-03-14 2020-11-30 Abbvie Inc Kombinacija dva antivirusa za lečenje hepatitisa c
CN105658219A (zh) 2013-10-25 2016-06-08 艾伯维公司 用于治疗hcv的方法
CN110302361A (zh) 2014-04-02 2019-10-08 艾伯维公司 治疗hcv的方法
US20180177779A1 (en) 2015-07-08 2018-06-28 Abbvie Inc. Methods for Treating HCV

Also Published As

Publication number Publication date
BR112016022976A2 (pt) 2017-08-15
JP2020063275A (ja) 2020-04-23
CN112704726A (zh) 2021-04-27
US20150283198A1 (en) 2015-10-08
JP6632992B2 (ja) 2020-01-22
US10286029B2 (en) 2019-05-14
MX388482B (es) 2025-03-20
JP2017509670A (ja) 2017-04-06
AU2020239800A1 (en) 2020-10-29
AU2015240754A1 (en) 2016-09-29
WO2015153793A1 (en) 2015-10-08
CA2942823C (en) 2023-01-03
BR112016022976A8 (pt) 2021-07-20
AU2015240754B2 (en) 2020-06-25
CN106413711A (zh) 2017-02-15
US20160317602A9 (en) 2016-11-03
CN112891511A (zh) 2021-06-04
EP3125889A1 (en) 2017-02-08
AU2022209336A1 (en) 2022-08-25
US20190336565A1 (en) 2019-11-07
CN110302361A (zh) 2019-10-08
CA2942823A1 (en) 2015-10-08

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