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MX2010003614A - Compuestos de diarilo oxadiazol. - Google Patents

Compuestos de diarilo oxadiazol.

Info

Publication number
MX2010003614A
MX2010003614A MX2010003614A MX2010003614A MX2010003614A MX 2010003614 A MX2010003614 A MX 2010003614A MX 2010003614 A MX2010003614 A MX 2010003614A MX 2010003614 A MX2010003614 A MX 2010003614A MX 2010003614 A MX2010003614 A MX 2010003614A
Authority
MX
Mexico
Prior art keywords
sup
diaryl compounds
compounds
oxadiazole
oxadiazole diaryl
Prior art date
Application number
MX2010003614A
Other languages
English (en)
Inventor
Wolfgang Sauer
Anna Quattropani
Agn S Bombrun
Cyril Montagne
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of MX2010003614A publication Critical patent/MX2010003614A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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Abstract

La invenci?n se refiere a compuestos de f?rmula (I): (ver f?rmula (I)) en donde R1, R2, Ra, Rb, Rc y W tienen los significados dados en la reivindicaci?n 1; los compuestos son ?tiles, por ejemplo, en el tratamiento de trastornos autoinmunes, tales como esclerosis m?ltiple.
MX2010003614A 2007-10-04 2008-10-01 Compuestos de diarilo oxadiazol. MX2010003614A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07117925 2007-10-04
US99813607P 2007-10-09 2007-10-09
PCT/EP2008/063185 WO2009043890A1 (en) 2007-10-04 2008-10-01 Oxadiazole diaryl compounds

Publications (1)

Publication Number Publication Date
MX2010003614A true MX2010003614A (es) 2010-04-21

Family

ID=38961274

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010003614A MX2010003614A (es) 2007-10-04 2008-10-01 Compuestos de diarilo oxadiazol.

Country Status (15)

Country Link
US (2) US8404676B2 (es)
EP (1) EP2193126B1 (es)
JP (3) JP5727223B2 (es)
KR (1) KR20100083814A (es)
CN (2) CN101815707B (es)
AR (1) AR068730A1 (es)
AU (1) AU2008306886B2 (es)
BR (1) BRPI0817597A2 (es)
CA (1) CA2696829C (es)
EA (1) EA201070423A1 (es)
ES (1) ES2547877T3 (es)
IL (1) IL204520A (es)
MX (1) MX2010003614A (es)
WO (1) WO2009043890A1 (es)
ZA (1) ZA201001217B (es)

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