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MX2008001982A - Compuestos nitro-o, sus composiciones farmaceuticas y sus usos. - Google Patents

Compuestos nitro-o, sus composiciones farmaceuticas y sus usos.

Info

Publication number
MX2008001982A
MX2008001982A MX2008001982A MX2008001982A MX2008001982A MX 2008001982 A MX2008001982 A MX 2008001982A MX 2008001982 A MX2008001982 A MX 2008001982A MX 2008001982 A MX2008001982 A MX 2008001982A MX 2008001982 A MX2008001982 A MX 2008001982A
Authority
MX
Mexico
Prior art keywords
nitro compounds
pharmaceutical compositons
pharmaceutical compositions
nitro
pharmaceutical
Prior art date
Application number
MX2008001982A
Other languages
English (en)
Inventor
Mark D Bednarski
Susan Knox
Louis Cannizzo
Kirsten Warner
Robert Wardle
Stephen Velarde
Shoucheng Ning
Original Assignee
Alliant Techsystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alliant Techsystems Inc filed Critical Alliant Techsystems Inc
Publication of MX2008001982A publication Critical patent/MX2008001982A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a compuestos nitro-O, las composiciones farmacéuticas de los compuestos-O y los métodos para utilizar los compuestos nitro-O y/o sus composiciones farmacéuticas, para tratar o prevenir enfermedades o desórdenes caracterizados por la proliferación celular anormal, como el cáncer, inflamación, enfermedades cardiovasculares y enfermedades autoinmunes.
MX2008001982A 2005-08-12 2006-08-14 Compuestos nitro-o, sus composiciones farmaceuticas y sus usos. MX2008001982A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70789605P 2005-08-12 2005-08-12
US11/502,974 US20070135380A1 (en) 2005-08-12 2006-08-11 O-nitro compounds, pharmaceutical compositions thereof and uses thereof
PCT/US2006/031722 WO2007022121A2 (en) 2005-08-12 2006-08-14 O-nitro compounds, pharmaceutical compositons thereof and uses thereof

Publications (1)

Publication Number Publication Date
MX2008001982A true MX2008001982A (es) 2008-09-26

Family

ID=37758284

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008001982A MX2008001982A (es) 2005-08-12 2006-08-14 Compuestos nitro-o, sus composiciones farmaceuticas y sus usos.

Country Status (9)

Country Link
US (3) US20070135380A1 (es)
EP (2) EP2433495B1 (es)
JP (1) JP5241494B2 (es)
KR (1) KR20090023327A (es)
AU (1) AU2006279678B8 (es)
CA (1) CA2620611C (es)
IL (1) IL189438A0 (es)
MX (1) MX2008001982A (es)
WO (1) WO2007022121A2 (es)

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US20070135380A1 (en) 2005-08-12 2007-06-14 Radiorx, Inc. O-nitro compounds, pharmaceutical compositions thereof and uses thereof
US7507842B2 (en) 2005-08-12 2009-03-24 Radiorx, Inc. Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof
JP5791064B2 (ja) * 2009-07-17 2015-10-07 エア・ウォーター株式会社 医薬用組成物
US8471041B2 (en) 2010-02-09 2013-06-25 Alliant Techsystems Inc. Methods of synthesizing and isolating N-(bromoacetyl)-3,3-dinitroazetidine and a composition including the same
US8664247B2 (en) 2011-08-26 2014-03-04 Radiorx, Inc. Acyclic organonitro compounds for use in treating cancer
ES2935573T3 (es) 2011-10-07 2023-03-08 Epicentrx Inc Compuestos de organonitro tioéter y usos médicos de estos
WO2013052803A2 (en) 2011-10-07 2013-04-11 Radiorx, Inc. Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products
US10342778B1 (en) 2015-10-20 2019-07-09 Epicentrx, Inc. Treatment of brain metastases using organonitro compound combination therapy
US9987270B1 (en) 2015-10-29 2018-06-05 Epicentrix, Inc. Treatment of gliomas using organonitro compound combination therapy
DK3402480T3 (da) 2016-01-11 2021-06-28 Epicentrx Inc Sammensætninger og fremgangsmåder til intravenøs administration af 2-brom-1-(3,3-dinitroazetidin-1-yl)ethanon
EA201990949A1 (ru) 2016-10-14 2019-10-31 Сульфоксиалкильные органические нитросоединения и родственные соединения и фармацевтические композиции для применения в медицине
SG11201914046WA (en) 2017-07-07 2020-01-30 Epicentrx Inc Compositions for parenteral administration of therapeutic agents
WO2019164593A2 (en) 2018-01-08 2019-08-29 Epicentrx, Inc. Methods and compositions utilizing rrx-001 combination therapy for radioprotection

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Also Published As

Publication number Publication date
KR20090023327A (ko) 2009-03-04
AU2006279678B2 (en) 2012-04-12
EP1924143A2 (en) 2008-05-28
AU2006279678B8 (en) 2012-05-10
WO2007022121A3 (en) 2007-07-19
US20120237615A1 (en) 2012-09-20
JP5241494B2 (ja) 2013-07-17
US8530681B2 (en) 2013-09-10
CA2620611A1 (en) 2007-02-22
EP1924143A4 (en) 2009-05-13
CA2620611C (en) 2017-01-03
US9133150B2 (en) 2015-09-15
EP2433495B1 (en) 2016-10-05
IL189438A0 (en) 2008-08-07
JP2009505982A (ja) 2009-02-12
WO2007022121A2 (en) 2007-02-22
EP2433495A1 (en) 2012-03-28
US20070135380A1 (en) 2007-06-14
AU2006279678A1 (en) 2007-02-22
US20130309324A1 (en) 2013-11-21

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Legal Events

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FA Abandonment or withdrawal