MX2010000522A - Proceso para la produccion del eter 1,2,2,2,-tetrafluoroetil difluorometilico (desflurano). - Google Patents
Proceso para la produccion del eter 1,2,2,2,-tetrafluoroetil difluorometilico (desflurano).Info
- Publication number
- MX2010000522A MX2010000522A MX2010000522A MX2010000522A MX2010000522A MX 2010000522 A MX2010000522 A MX 2010000522A MX 2010000522 A MX2010000522 A MX 2010000522A MX 2010000522 A MX2010000522 A MX 2010000522A MX 2010000522 A MX2010000522 A MX 2010000522A
- Authority
- MX
- Mexico
- Prior art keywords
- desflurane
- difluoromethyl ether
- production
- tetrafluoroethyl difluoromethyl
- reactor
- Prior art date
Links
- DPYMFVXJLLWWEU-UHFFFAOYSA-N desflurane Chemical compound FC(F)OC(F)C(F)(F)F DPYMFVXJLLWWEU-UHFFFAOYSA-N 0.000 title abstract 8
- 229960003537 desflurane Drugs 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- PIWKPBJCKXDKJR-UHFFFAOYSA-N Isoflurane Chemical compound FC(F)OC(Cl)C(F)(F)F PIWKPBJCKXDKJR-UHFFFAOYSA-N 0.000 abstract 2
- 229960002725 isoflurane Drugs 0.000 abstract 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000010924 continuous production Methods 0.000 abstract 1
- 238000003682 fluorination reaction Methods 0.000 abstract 1
- 229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La presente invenci?n proporciona un proceso continuo para la producci?n del ?ter 1,2,2,2-tetrafluoroetil difluoromet?lico(desfl urano), que comprende alimentar de manera continua cantidades molares ?ptimas del ?ter 1-cloro-2,2,2-trifluoroetil difluoromet?lico (CF3CHCIOCHF2, isoflurano), y ?cido fluorh?drico anhidro, en un reactor en la fase vapor sobre un sistema de catalizador de fluoraci?n, que comprende un pentahaluro met?lico absorbido en un sustrato de soporte a una temperatura que var?a de 100?C a 180?C, y separar el ?ter 1,2,2,2-tetrafluoroetil difluoromet?lico (desflurano) de manera continua del reactor. El proceso de la presente invenci?n permite el retiro continuo del producto desflurano, reduciendo al m?nimo por lo tanto, la coproducci?n de subproductos y resultado en una alta eficiencia de conversi?n y rendimiento de desflurano.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1343MU2007 | 2007-07-13 | ||
| PCT/IB2008/052801 WO2009010908A2 (en) | 2007-07-13 | 2008-07-11 | Process for production of 1,2,2,2-tetrafluoroethyl difluoromethyl ether (desflurane) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010000522A true MX2010000522A (es) | 2010-04-01 |
Family
ID=40260165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010000522A MX2010000522A (es) | 2007-07-13 | 2008-07-11 | Proceso para la produccion del eter 1,2,2,2,-tetrafluoroetil difluorometilico (desflurano). |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8378149B2 (es) |
| EP (1) | EP2167453A4 (es) |
| JP (1) | JP2010533211A (es) |
| CN (1) | CN101743215A (es) |
| AR (1) | AR070010A1 (es) |
| AU (1) | AU2008277290B2 (es) |
| BR (1) | BRPI0814554A2 (es) |
| CA (1) | CA2692874A1 (es) |
| MX (1) | MX2010000522A (es) |
| TW (1) | TW200909404A (es) |
| WO (1) | WO2009010908A2 (es) |
| ZA (1) | ZA201001059B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6886104B2 (ja) | 2016-12-29 | 2021-06-16 | セントラル硝子株式会社 | ハロゲン化α−フルオロエーテル類の製造方法 |
| US10683252B2 (en) | 2016-12-29 | 2020-06-16 | Central Glass Company, Limited | Production method for 1,2,2,2-tetrafluoroethyl difluoromethyl ether (desflurane) |
| JP2019064948A (ja) * | 2017-09-29 | 2019-04-25 | セントラル硝子株式会社 | １，２，２，２−テトラフルオロエチルジフルオロメチルエーテル（デスフルラン）の製造方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2478362A (en) | 1948-06-15 | 1949-08-09 | Kinetic Chemicals Inc | Distillation process for separating products of perchloro-ethylene fluorination |
| US3535388A (en) | 1969-05-12 | 1970-10-20 | Air Reduction | 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether |
| US3897502A (en) | 1971-10-22 | 1975-07-29 | Airco Inc | Process for making fluorinated ethers |
| DE2361058A1 (de) | 1973-12-07 | 1975-06-19 | Hoechst Ag | 1.2.2.2-tetrafluoraethyl-chlorfluormethylaether und verfahren zu dessen herstellung |
| DE2546532C2 (de) * | 1975-10-17 | 1977-11-17 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von Trichlormethyl-trifluormethylbenzolen |
| US4436942A (en) | 1977-10-27 | 1984-03-13 | Occidental Chemical Corporation | Process for the catalyzed fluorination of haloalkyl aromatic compounds |
| FR2501064A1 (fr) * | 1980-12-29 | 1982-09-10 | Ugine Kuhlmann | Catalyseurs de fluoruration en phase gazeuse des hydrocarbures chlores et chlorofluores aliphatiques, a base d'oxyde de chrome depose sur charbon actif, et procedes de fluoruration utilisant ces catalyseurs |
| US4762856A (en) | 1987-02-02 | 1988-08-09 | Boc, Inc. | Anesthetic composition and method of using the same |
| US4874901A (en) | 1988-05-06 | 1989-10-17 | Boc, Inc. | Process for the production of polyfluorinated ethers |
| US5015781A (en) | 1988-05-06 | 1991-05-14 | Boc, Inc. | Anesthetic compound and method of preparing |
| JPH01301636A (ja) | 1988-05-31 | 1989-12-05 | Central Glass Co Ltd | １，２，２，２−テトラフルオロエチルジフルオロメチルエーテルの製造法 |
| US5026924A (en) | 1989-03-14 | 1991-06-25 | Anaquest, Inc. | Process for production of 1,2,2,2-tetrafluoroethyl difluoromethyl ether |
| GB9023370D0 (en) | 1990-10-26 | 1990-12-05 | Rhone Poulenc Chemicals | Synthesis of fluorinated substituted ethanes |
| EP0712826A1 (en) * | 1994-11-17 | 1996-05-22 | Elf Atochem North America, Inc. | 1,1,1-Trifluoroethane synthesis using a supported lewis acid |
| AU6997296A (en) | 1995-10-10 | 1997-04-30 | Imperial Chemical Industries Plc | Hydrogen fluoride recovery process |
| JP2001508102A (ja) * | 1997-01-08 | 2001-06-19 | ハーキュリーズ・インコーポレーテッド | 炭化水素樹脂の製造のための触媒としての金属酸化物固体酸 |
| US6074985A (en) | 1999-08-03 | 2000-06-13 | Elf Atochem North America, Inc. | Fluorination catalysts |
| JP3837628B2 (ja) * | 2000-09-08 | 2006-10-25 | 独立行政法人産業技術総合研究所 | １−クロロ−１，１，２，２−テトラフロロ−２−メトキシエタン及びその製造方法 |
| US6635231B2 (en) | 2001-03-06 | 2003-10-21 | Lithdyne International | Preparation of arsenic pentafluoride |
| US6800786B1 (en) | 2002-09-25 | 2004-10-05 | Baxter International, Inc. | Preparation of desflurane |
| NZ555173A (en) * | 2004-11-17 | 2010-04-30 | Piramal Critical Care Inc | Process for producing desflurane from isoflurane with antimony pentafluoride and HF |
| ES2406004T3 (es) * | 2005-01-12 | 2013-06-04 | Halocarbon Products Corporation | Síntesis de éteres fluorados |
| BRPI0607384A2 (pt) | 2005-02-15 | 2009-09-01 | Halocarbon Prod Corp | separação/purificação de desflurano do fluoreto de hidrogênio |
-
2008
- 2008-07-11 MX MX2010000522A patent/MX2010000522A/es active IP Right Grant
- 2008-07-11 BR BRPI0814554-7A2A patent/BRPI0814554A2/pt not_active IP Right Cessation
- 2008-07-11 EP EP08789277A patent/EP2167453A4/en not_active Withdrawn
- 2008-07-11 CN CN200880024550A patent/CN101743215A/zh active Pending
- 2008-07-11 AR ARP080103001A patent/AR070010A1/es not_active Application Discontinuation
- 2008-07-11 CA CA 2692874 patent/CA2692874A1/en not_active Abandoned
- 2008-07-11 WO PCT/IB2008/052801 patent/WO2009010908A2/en not_active Ceased
- 2008-07-11 AU AU2008277290A patent/AU2008277290B2/en not_active Ceased
- 2008-07-11 TW TW097126467A patent/TW200909404A/zh unknown
- 2008-07-11 US US12/668,984 patent/US8378149B2/en not_active Expired - Fee Related
- 2008-07-11 JP JP2010516622A patent/JP2010533211A/ja not_active Ceased
-
2010
- 2010-02-12 ZA ZA201001059A patent/ZA201001059B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0814554A2 (pt) | 2015-01-06 |
| AR070010A1 (es) | 2010-03-10 |
| US20100185020A1 (en) | 2010-07-22 |
| AU2008277290B2 (en) | 2013-09-05 |
| AU2008277290A1 (en) | 2009-01-22 |
| CN101743215A (zh) | 2010-06-16 |
| WO2009010908A2 (en) | 2009-01-22 |
| EP2167453A2 (en) | 2010-03-31 |
| EP2167453A4 (en) | 2013-03-06 |
| TW200909404A (en) | 2009-03-01 |
| WO2009010908A3 (en) | 2009-12-30 |
| ZA201001059B (en) | 2010-10-27 |
| JP2010533211A (ja) | 2010-10-21 |
| US8378149B2 (en) | 2013-02-19 |
| CA2692874A1 (en) | 2009-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |