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AR070010A1 - Proceso para la produccion de 1,2,2,2 -eter tetrafluoroetil difluorometilo (desflurano) - Google Patents

Proceso para la produccion de 1,2,2,2 -eter tetrafluoroetil difluorometilo (desflurano)

Info

Publication number
AR070010A1
AR070010A1 ARP080103001A ARP080103001A AR070010A1 AR 070010 A1 AR070010 A1 AR 070010A1 AR P080103001 A ARP080103001 A AR P080103001A AR P080103001 A ARP080103001 A AR P080103001A AR 070010 A1 AR070010 A1 AR 070010A1
Authority
AR
Argentina
Prior art keywords
desflurane
production
difluoromethyl ether
tetrafluoroetil
difluorometilo
Prior art date
Application number
ARP080103001A
Other languages
English (en)
Inventor
Damodharan Satagopan
Abhay Atmaram Upare
Hariharan Sivaramakrishnan
Owen Chambers
Original Assignee
Piramal Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Piramal Healthcare Ltd filed Critical Piramal Healthcare Ltd
Publication of AR070010A1 publication Critical patent/AR070010A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

El presente invento proporciona un proceso continuo para la produccion de 1,2,2,2-éter tetrafluoroetil difluorometilo (desflurano) que comprende la alimentacion en forma continua de cantidades molares optimas de 1-cloro-2,2,2-éter trifluoroetil difluorometilo (CF3CHCIOCHF2, Isoflurano) y fluoruro de hidrogeno anhidro, en un reactor en la fase de vapor sobre un sistema de catalizador de fluorizacion que comprende un pentahaluro metálico absorbido sobre un sustrato de soporte a un temperatura que oscila de 100°C a 180C y separando 1,2,2,2-éter tetrafluoroetil difluorometilo (desflurano) en forma continua del reactor. El proceso del presente invento permite la remocion continua del producto desflurano, por lo tanto minimizando la co-produccion de subproductos y dando por resultado alta eficiencia de conversion y rendimiento de desflurano.
ARP080103001A 2007-07-13 2008-07-11 Proceso para la produccion de 1,2,2,2 -eter tetrafluoroetil difluorometilo (desflurano) AR070010A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1343MU2007 2007-07-13

Publications (1)

Publication Number Publication Date
AR070010A1 true AR070010A1 (es) 2010-03-10

Family

ID=40260165

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080103001A AR070010A1 (es) 2007-07-13 2008-07-11 Proceso para la produccion de 1,2,2,2 -eter tetrafluoroetil difluorometilo (desflurano)

Country Status (12)

Country Link
US (1) US8378149B2 (es)
EP (1) EP2167453A4 (es)
JP (1) JP2010533211A (es)
CN (1) CN101743215A (es)
AR (1) AR070010A1 (es)
AU (1) AU2008277290B2 (es)
BR (1) BRPI0814554A2 (es)
CA (1) CA2692874A1 (es)
MX (1) MX2010000522A (es)
TW (1) TW200909404A (es)
WO (1) WO2009010908A2 (es)
ZA (1) ZA201001059B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6886104B2 (ja) 2016-12-29 2021-06-16 セントラル硝子株式会社 ハロゲン化α−フルオロエーテル類の製造方法
US10683252B2 (en) 2016-12-29 2020-06-16 Central Glass Company, Limited Production method for 1,2,2,2-tetrafluoroethyl difluoromethyl ether (desflurane)
JP2019064948A (ja) * 2017-09-29 2019-04-25 セントラル硝子株式会社 １，２，２，２−テトラフルオロエチルジフルオロメチルエーテル（デスフルラン）の製造方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2478362A (en) * 1948-06-15 1949-08-09 Kinetic Chemicals Inc Distillation process for separating products of perchloro-ethylene fluorination
US3535388A (en) * 1969-05-12 1970-10-20 Air Reduction 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether
US3897502A (en) * 1971-10-22 1975-07-29 Airco Inc Process for making fluorinated ethers
DE2361058A1 (de) 1973-12-07 1975-06-19 Hoechst Ag 1.2.2.2-tetrafluoraethyl-chlorfluormethylaether und verfahren zu dessen herstellung
DE2546532C2 (de) * 1975-10-17 1977-11-17 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Trichlormethyl-trifluormethylbenzolen
US4436942A (en) * 1977-10-27 1984-03-13 Occidental Chemical Corporation Process for the catalyzed fluorination of haloalkyl aromatic compounds
FR2501064A1 (fr) * 1980-12-29 1982-09-10 Ugine Kuhlmann Catalyseurs de fluoruration en phase gazeuse des hydrocarbures chlores et chlorofluores aliphatiques, a base d'oxyde de chrome depose sur charbon actif, et procedes de fluoruration utilisant ces catalyseurs
US4762856A (en) * 1987-02-02 1988-08-09 Boc, Inc. Anesthetic composition and method of using the same
US5015781A (en) * 1988-05-06 1991-05-14 Boc, Inc. Anesthetic compound and method of preparing
US4874901A (en) 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
JPH01301636A (ja) 1988-05-31 1989-12-05 Central Glass Co Ltd １，２，２，２−テトラフルオロエチルジフルオロメチルエーテルの製造法
US5026924A (en) * 1989-03-14 1991-06-25 Anaquest, Inc. Process for production of 1,2,2,2-tetrafluoroethyl difluoromethyl ether
GB9023370D0 (en) * 1990-10-26 1990-12-05 Rhone Poulenc Chemicals Synthesis of fluorinated substituted ethanes
EP0712826A1 (en) * 1994-11-17 1996-05-22 Elf Atochem North America, Inc. 1,1,1-Trifluoroethane synthesis using a supported lewis acid
DE69611307T2 (de) * 1995-10-10 2001-04-26 Imperial Chemical Industries Plc, London Verfahren zur rückgewinnung von wasserstofffluorid
US6310154B1 (en) * 1997-01-08 2001-10-30 Eastman Chemical Company Solid acids as catalysts for the preparation of hydrocarbon resins
US6074985A (en) * 1999-08-03 2000-06-13 Elf Atochem North America, Inc. Fluorination catalysts
JP3837628B2 (ja) * 2000-09-08 2006-10-25 独立行政法人産業技術総合研究所 １−クロロ−１，１，２，２−テトラフロロ−２−メトキシエタン及びその製造方法
US6635231B2 (en) * 2001-03-06 2003-10-21 Lithdyne International Preparation of arsenic pentafluoride
US6800786B1 (en) * 2002-09-25 2004-10-05 Baxter International, Inc. Preparation of desflurane
EA012298B1 (ru) * 2004-11-17 2009-08-28 Минрад Инк. Способ получения 1,2,2,2-тетрафторэтилдифторметилового эфира
EP1843996B1 (en) * 2005-01-12 2013-04-10 Halocarbon Products Corporation Synthesis of fluorinated ethers
JP5432454B2 (ja) 2005-02-15 2014-03-05 ヘイロウカーボン プロダクツ コーポレイション フッ化水素からのデスフルランの分離／精製方法

Also Published As

Publication number Publication date
EP2167453A4 (en) 2013-03-06
WO2009010908A2 (en) 2009-01-22
US20100185020A1 (en) 2010-07-22
US8378149B2 (en) 2013-02-19
ZA201001059B (en) 2010-10-27
AU2008277290A1 (en) 2009-01-22
CA2692874A1 (en) 2009-01-22
MX2010000522A (es) 2010-04-01
BRPI0814554A2 (pt) 2015-01-06
AU2008277290B2 (en) 2013-09-05
WO2009010908A3 (en) 2009-12-30
TW200909404A (en) 2009-03-01
EP2167453A2 (en) 2010-03-31
CN101743215A (zh) 2010-06-16
JP2010533211A (ja) 2010-10-21

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