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MX2009006009A - Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulacion de la actividad del adrenoreceptor beta 2. - Google Patents

Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulacion de la actividad del adrenoreceptor beta 2.

Info

Publication number
MX2009006009A
MX2009006009A MX2009006009A MX2009006009A MX2009006009A MX 2009006009 A MX2009006009 A MX 2009006009A MX 2009006009 A MX2009006009 A MX 2009006009A MX 2009006009 A MX2009006009 A MX 2009006009A MX 2009006009 A MX2009006009 A MX 2009006009A
Authority
MX
Mexico
Prior art keywords
compounds
hydr0xy
benzothiazol
dihydro
modulation
Prior art date
Application number
MX2009006009A
Other languages
English (en)
Inventor
Stephen Connolly
Premji Meghani
Alexander Humphries
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2009006009A publication Critical patent/MX2009006009A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invención proporciona los compuestos de la fórmula (I) donde Ra, Rb, R1, R2, R3, R4, R5, R6 y R29 son como se definió en la descripción, los procesos para su preparación, las composiciones farmacéuticas que los contienen y su uso en terapia.
MX2009006009A 2006-12-20 2007-12-19 Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulacion de la actividad del adrenoreceptor beta 2. MX2009006009A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87092206P 2006-12-20 2006-12-20
US91004507P 2007-04-04 2007-04-04
US95198007P 2007-07-26 2007-07-26
PCT/GB2007/004861 WO2008075026A1 (en) 2006-12-20 2007-12-19 4-hydr0xy-2-0x0-2, 3 -dihydro- 1, 3-benzothiazol- 7yl compounds for modulation of b2-adrenoreceptor activity

Publications (1)

Publication Number Publication Date
MX2009006009A true MX2009006009A (es) 2009-06-16

Family

ID=39167020

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006009A MX2009006009A (es) 2006-12-20 2007-12-19 Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulacion de la actividad del adrenoreceptor beta 2.

Country Status (20)

Country Link
US (3) US7700782B2 (es)
EP (1) EP2121642B1 (es)
JP (1) JP2010513440A (es)
KR (1) KR20090091342A (es)
AR (1) AR064635A1 (es)
AT (1) ATE517879T1 (es)
AU (1) AU2007336075B2 (es)
BR (1) BRPI0722096A2 (es)
CA (1) CA2672811A1 (es)
CL (1) CL2007003765A1 (es)
CO (1) CO6190554A2 (es)
EC (1) ECSP099426A (es)
IL (1) IL199014A0 (es)
MX (1) MX2009006009A (es)
NO (1) NO20092691L (es)
PE (1) PE20081544A1 (es)
SA (1) SA07280728B1 (es)
TW (1) TW200833670A (es)
UY (1) UY30808A1 (es)
WO (1) WO2008075026A1 (es)

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TW200833670A (en) * 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) * 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
BRPI0822693A2 (pt) 2008-05-13 2015-07-07 Astrazeneca Ab Derivados de quinuclidina como antagonistas do receptor muscarínico m3
AU2009247021B2 (en) * 2008-05-13 2012-06-07 Astrazeneca Ab Pharmaceutical product comprising a muscarinic receptor antagonist and a beta2-adrenoceptor agonist
KR20110017456A (ko) 2008-06-18 2011-02-21 아스트라제네카 아베 호흡기 장애의 치료를 위한 베타2-아드레날린성 수용체 효능제로서 작용하는 벤족사지논 유도체
EP2303266A4 (en) * 2008-06-20 2015-01-21 Astrazeneca Ab PHARMACEUTICAL COMPOSITION COMPRISING A 4-HYDROXY-2-OXO-2,3-DIHYDRO-1,3-BENZOTHIAZOL-7-YLE COMPOUND FOR THE MODULATION OF BETA-2-ADRENORECEPTOR ACTIVITY
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GB201016912D0 (en) 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
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Also Published As

Publication number Publication date
NO20092691L (no) 2009-09-16
WO2008075026A1 (en) 2008-06-26
UY30808A1 (es) 2008-07-31
HK1136572A1 (en) 2010-07-02
SA07280728B1 (ar) 2010-12-01
BRPI0722096A2 (pt) 2014-04-01
PE20081544A1 (es) 2009-01-11
AU2007336075B2 (en) 2011-10-27
US20100249200A1 (en) 2010-09-30
EP2121642A1 (en) 2009-11-25
CO6190554A2 (es) 2010-08-19
US20100022491A1 (en) 2010-01-28
AU2007336075A1 (en) 2008-06-26
EP2121642B1 (en) 2011-07-27
US7700782B2 (en) 2010-04-20
AR064635A1 (es) 2009-04-15
US20080207698A1 (en) 2008-08-28
ECSP099426A (es) 2009-07-31
IL199014A0 (en) 2010-02-17
JP2010513440A (ja) 2010-04-30
CL2007003765A1 (es) 2008-08-22
CA2672811A1 (en) 2008-06-26
KR20090091342A (ko) 2009-08-27
TW200833670A (en) 2008-08-16
ATE517879T1 (de) 2011-08-15

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