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MX2008014873A - Inhibidores de metaloproteasa heterobiciclicas. - Google Patents

Inhibidores de metaloproteasa heterobiciclicas.

Info

Publication number
MX2008014873A
MX2008014873A MX2008014873A MX2008014873A MX2008014873A MX 2008014873 A MX2008014873 A MX 2008014873A MX 2008014873 A MX2008014873 A MX 2008014873A MX 2008014873 A MX2008014873 A MX 2008014873A MX 2008014873 A MX2008014873 A MX 2008014873A
Authority
MX
Mexico
Prior art keywords
mmp
heterobicyclic
metalloprotease inhibitors
heterobicyclic metalloprotease
present
Prior art date
Application number
MX2008014873A
Other languages
English (en)
Inventor
Frank Richter
Matthias Schneider
Arthur G Taveras
Christoph Steeneck
Matthias Hochguertel
Harald Bluhm
Irving Sucholeiki
Xinyuan Wu
Bert Nolte
Joshua Van Veldhuizen
Hongbo Deng
Michael Essers
Heiko Kroth
Christian Gege
Tim Feuerstein
Torsten Arndt
Ralf Biesinger
Brian M Gallagher Jr
Original Assignee
Alantos Pharm Holding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/440,087 external-priority patent/US20060293345A1/en
Application filed by Alantos Pharm Holding filed Critical Alantos Pharm Holding
Publication of MX2008014873A publication Critical patent/MX2008014873A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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  • Health & Medical Sciences (AREA)
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Abstract

La presente invención se refiere generalmente a grupo amida que contiene agentes farmacéuticos, y en particular, a amida que contiene compuestos de inhibidor de metaloproteasa heterobicíclica. Más particularmente, la presente invención proporciona una nueva clase de compuestos MMP-13 heterobicíclica que inhibe y MMP-3 que inhibe, que exhiben una potencia incrementada en relación a inhibidores MMP-13 y MMP-3 actualmente conocidos.
MX2008014873A 2006-05-22 2007-05-22 Inhibidores de metaloproteasa heterobiciclicas. MX2008014873A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/440,087 US20060293345A1 (en) 2005-05-20 2006-05-22 Heterobicyclic metalloprotease inhibitors
US11/602,140 US20070155738A1 (en) 2005-05-20 2006-11-20 Heterobicyclic metalloprotease inhibitors
PCT/US2007/012337 WO2007139856A2 (en) 2006-05-22 2007-05-22 Heterobicyclic metalloprotease inhibitors

Publications (1)

Publication Number Publication Date
MX2008014873A true MX2008014873A (es) 2009-05-05

Family

ID=40158159

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008014873A MX2008014873A (es) 2006-05-22 2007-05-22 Inhibidores de metaloproteasa heterobiciclicas.

Country Status (7)

Country Link
US (4) US20070155738A1 (es)
EP (1) EP2038283A2 (es)
JP (1) JP2009538314A (es)
AU (1) AU2007267936A1 (es)
CA (1) CA2653131A1 (es)
MX (1) MX2008014873A (es)
WO (1) WO2007139856A2 (es)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070155738A1 (en) * 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
US20070155737A1 (en) * 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
AU2006251989B2 (en) * 2005-05-20 2010-05-27 Alantos-Pharmaceuticals, Inc. Pyrimidine or triazine fused bicyclic metalloprotease inhibitors
ES2645995T3 (es) * 2006-05-31 2017-12-11 Abbvie Inc. Compuestos como ligandos del receptor cannabinoide y sus usos
US8841334B2 (en) * 2006-05-31 2014-09-23 Abbvie Inc. Compounds as cannabinoid receptor ligands and uses thereof
WO2008063671A2 (en) * 2006-11-20 2008-05-29 Alantos Pharmaceuticals Holding, Inc. Heterobicyclic metalloprotease inhibitors
MX2009005478A (es) * 2006-11-27 2009-08-12 Lundbeck & Co As H Derivados de heteroarilamida.
WO2008064432A1 (en) * 2006-12-01 2008-06-05 The University Of Sydney Polycyclic molecular compounds
CA2680312A1 (en) 2007-03-07 2008-09-12 Alantos Pharmaceuticals Holding, Inc. Metalloprotease inhibitors containing a heterocyclic moiety
WO2008121558A1 (en) 2007-03-28 2008-10-09 Abbott Laboratories 1, 3-thiazol-2 (3h) -ylidene compounds as cannabinoid receptor ligands
US7872033B2 (en) * 2007-04-17 2011-01-18 Abbott Laboratories Compounds as cannabinoid receptor ligands
JP2010527929A (ja) * 2007-05-18 2010-08-19 アボット・ラボラトリーズ カンナビノイド受容体リガンドとしての新規な化合物
KR20100065340A (ko) 2007-08-27 2010-06-16 바스프 에스이 무척추 해충을 방제하기 위한 피라졸 화합물
US9193713B2 (en) * 2007-10-12 2015-11-24 Abbvie Inc. Compounds as cannabinoid receptor ligands
US9216983B2 (en) * 2007-12-21 2015-12-22 Board Of Regents, University Of Texas System Dihydroorotate dehydrogenase inhibitors with selective anti-malarial activity
US8846730B2 (en) * 2008-09-08 2014-09-30 Abbvie Inc. Compounds as cannabinoid receptor ligands
AR073599A1 (es) * 2008-09-16 2010-11-17 Abbott Lab Compuestos heterociclicos como ligandos de receptores de canabinoides
JP5536073B2 (ja) 2008-09-24 2014-07-02 ビーエーエスエフ ソシエタス・ヨーロピア 無脊椎動物系害虫を防除するためのピラゾール化合物
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US20090137547A1 (en) 2009-05-28
US8835441B2 (en) 2014-09-16
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AU2007267936A1 (en) 2007-12-06
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