MA33214B1 - Compose pyrazole - Google Patents
Compose pyrazoleInfo
- Publication number
- MA33214B1 MA33214B1 MA34275A MA34275A MA33214B1 MA 33214 B1 MA33214 B1 MA 33214B1 MA 34275 A MA34275 A MA 34275A MA 34275 A MA34275 A MA 34275A MA 33214 B1 MA33214 B1 MA 33214B1
- Authority
- MA
- Morocco
- Prior art keywords
- atom
- hydrogen atom
- substituted
- halogen
- substituent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE UN COMPOSÉ AYANT UNE EXCELLENTE ACTIVITÉ INHIBITRICE SUR LA SÉCRÉTION D'UN ACIDE ET PRÉSENTANT ENTRE AUTRES UNE ACTIVITÉ ANTITUMORALE. LA PRÉSENTE INVENTION CONCERNE SPÉCIFIQUEMENT UN COMPOSÉ REPRÉSENTÉ PAR LA FORMULE (1) [DANS LAQUELLE R1 REPRÉSENTE UN SUBSTITUANT; R2 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, OU UN GROUPE CYANO; ET R3 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN ATOME D'HALOGÈNE, UN GROUPE CYANO, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, UN GROUPE ALCOXY EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE; L'UN DES R2 ET R3 REPRÉSENTANT UN ATOME D'HYDROGÈNE ET L'AUTRE REPRÉSENTANT UN SUBSTITUANT AUTRE QU'UN ATOME D'HYDROGÈNE] OU UN SEL DE CELUI-CI.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009077078 | 2009-03-26 | ||
| PCT/JP2010/055257 WO2010110378A1 (fr) | 2009-03-26 | 2010-03-25 | Composé pyrazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33214B1 true MA33214B1 (fr) | 2012-04-02 |
Family
ID=42781069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34275A MA33214B1 (fr) | 2009-03-26 | 2010-03-25 | Compose pyrazole |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8895588B2 (fr) |
| EP (1) | EP2412713B1 (fr) |
| JP (1) | JP5552481B2 (fr) |
| KR (1) | KR101656906B1 (fr) |
| CN (1) | CN102448953B (fr) |
| AU (1) | AU2010228220B2 (fr) |
| BR (1) | BRPI1009090A2 (fr) |
| CA (1) | CA2756086A1 (fr) |
| CL (1) | CL2011002351A1 (fr) |
| CO (1) | CO6460700A2 (fr) |
| CR (1) | CR20110533A (fr) |
| DO (1) | DOP2011000296A (fr) |
| EA (1) | EA019853B1 (fr) |
| EC (1) | ECSP11011419A (fr) |
| GE (1) | GEP20156222B (fr) |
| IL (1) | IL215235A (fr) |
| MA (1) | MA33214B1 (fr) |
| MX (1) | MX2011009943A (fr) |
| NZ (1) | NZ595890A (fr) |
| PE (1) | PE20120618A1 (fr) |
| SG (1) | SG174476A1 (fr) |
| TN (1) | TN2011000474A1 (fr) |
| UA (1) | UA107457C2 (fr) |
| WO (1) | WO2010110378A1 (fr) |
| ZA (1) | ZA201107435B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110917130A (zh) | 2012-06-27 | 2020-03-27 | 武田药品工业株式会社 | 用盐稳定的胺和有机酸的液体制剂 |
| ES2959427T3 (es) * | 2012-09-27 | 2024-02-26 | Elanco Animal Health Incorporated | Composiciones farmacéuticas para el tratamiento de la inapetencia |
| KR20180108916A (ko) | 2015-01-28 | 2018-10-04 | 아라타나 세라퓨틱스, 인크. | 체중-증량 화합물의 장기 사용을 위한 조성물 및 방법 |
| CN105067814A (zh) * | 2015-07-24 | 2015-11-18 | 中国科学院成都生物研究所 | 解旋酶水解atp活性测定方法 |
| HUE070031T2 (hu) * | 2020-06-17 | 2025-05-28 | Ildong Pharmaceutical Co Ltd | Új savszekréciós inhibitor és alkalmazása |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3285991A (en) | 1963-03-26 | 1966-11-15 | Union Carbide Corp | Polyepoxides cured with the reaction product of a dihydroxydiphenylsul-fone, an amine, and an aldehyde |
| US4847289A (en) | 1987-06-08 | 1989-07-11 | Merck & Co., Inc. | Thiophene sulfonamide antiglaucoma agents |
| ZA927272B (en) | 1991-10-29 | 1994-03-23 | Du Pont | Herbicidal triazolecarboxamides |
| MX9702030A (es) | 1994-09-26 | 1997-06-28 | Shionogi & Co | Derivado de imidazol. |
| JPH0948778A (ja) | 1995-08-04 | 1997-02-18 | Sagami Chem Res Center | ２−置換−３−アルコキシ−５−（ピロール−２−イル）フラン誘導体 |
| ATE236632T1 (de) | 1995-11-06 | 2003-04-15 | Univ Pittsburgh | Inhibitoren der protein-isoprenyl-transferase |
| HUP0000735A3 (en) | 1996-12-23 | 2002-03-28 | Bristol Myers Squibb Pharma Co | Nitrogen containing heteroaromatics as factor xa inhibitors |
| AU1918299A (en) | 1998-02-23 | 1999-09-06 | Warner-Lambert Company | Substituted quinoxaline derivatives as interleukin-8 receptor antagonists |
| WO2004012659A2 (fr) | 2002-08-01 | 2004-02-12 | Nitromed, Inc. | Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation |
| ES2314418T3 (es) | 2003-05-02 | 2009-03-16 | Elan Pharmaceuticals, Inc. | Derivados de amidas del acido 4-bromo-5-(2-clorobenzoilamino)-1h-pirazol-3-carboxicilico y compuestos relacionados como antagonistas del receptor b1 de bradiquinina para el tratamiento de enfermedades inflamatorias. |
| JP4716996B2 (ja) | 2003-05-26 | 2011-07-06 | 武田薬品工業株式会社 | スルホピロール |
| US7872014B2 (en) | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
| EP1803709B1 (fr) | 2004-09-30 | 2013-01-02 | Takeda Pharmaceutical Company Limited | Inhibiteurs de pompe a protons |
| ATE504567T1 (de) * | 2005-08-30 | 2011-04-15 | Takeda Pharmaceutical | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl-substitutierte 1-h-pyrrolderivate als säuresekretionshemmer |
| US7994205B2 (en) | 2006-03-31 | 2011-08-09 | Takeda Pharmaceutical Company Limited | Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors |
| US8933105B2 (en) * | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| JP2009077078A (ja) | 2007-09-19 | 2009-04-09 | Brother Ind Ltd | 位置検出システム |
| EP2196459B1 (fr) | 2007-09-28 | 2016-11-02 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique à 5 chaînons |
| WO2009041705A2 (fr) | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique à 5 chaînons |
| PE20091846A1 (es) | 2008-05-19 | 2009-12-16 | Plexxikon Inc | DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS |
| MX2011000460A (es) | 2008-07-18 | 2011-03-15 | Takeda Pharmaceutical | Derivados de benzazepina y su uso como antagonistas de histamina h3. |
-
2010
- 2010-03-25 BR BRPI1009090A patent/BRPI1009090A2/pt not_active IP Right Cessation
- 2010-03-25 AU AU2010228220A patent/AU2010228220B2/en not_active Ceased
- 2010-03-25 GE GEAP201012426A patent/GEP20156222B/en unknown
- 2010-03-25 US US13/260,507 patent/US8895588B2/en active Active
- 2010-03-25 UA UAA201112488A patent/UA107457C2/uk unknown
- 2010-03-25 MA MA34275A patent/MA33214B1/fr unknown
- 2010-03-25 CA CA2756086A patent/CA2756086A1/fr not_active Abandoned
- 2010-03-25 CN CN201080023162.7A patent/CN102448953B/zh active Active
- 2010-03-25 EA EA201171168A patent/EA019853B1/ru not_active IP Right Cessation
- 2010-03-25 PE PE2011001696A patent/PE20120618A1/es not_active Application Discontinuation
- 2010-03-25 WO PCT/JP2010/055257 patent/WO2010110378A1/fr not_active Ceased
- 2010-03-25 EP EP10756174.8A patent/EP2412713B1/fr active Active
- 2010-03-25 SG SG2011067808A patent/SG174476A1/en unknown
- 2010-03-25 JP JP2011506117A patent/JP5552481B2/ja active Active
- 2010-03-25 KR KR1020117024240A patent/KR101656906B1/ko active Active
- 2010-03-25 MX MX2011009943A patent/MX2011009943A/es active IP Right Grant
- 2010-03-25 NZ NZ595890A patent/NZ595890A/xx not_active IP Right Cessation
-
2011
- 2011-08-25 EC EC2011011419A patent/ECSP11011419A/es unknown
- 2011-09-19 IL IL215235A patent/IL215235A/en not_active IP Right Cessation
- 2011-09-21 TN TN2011000474A patent/TN2011000474A1/fr unknown
- 2011-09-23 CL CL2011002351A patent/CL2011002351A1/es unknown
- 2011-09-23 DO DO2011000296A patent/DOP2011000296A/es unknown
- 2011-10-11 ZA ZA2011/07435A patent/ZA201107435B/en unknown
- 2011-10-12 CR CR20110533A patent/CR20110533A/es unknown
- 2011-10-26 CO CO11144548A patent/CO6460700A2/es active IP Right Grant
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