MA27183A1 - Composes oxo-azabicycliques - Google Patents

Composes oxo-azabicycliques

Info

Publication number: MA27183A1
Authority: MA; Morocco
Prior art keywords: group; atom; description; chosen; inclusive
Prior art date: 2002-03-08

Application number

MA27842A

Other languages

English (en)

French (fr)

Inventor

Bernard Gaudilliere

Catherine Kostlan

Wen-Song Yue

Henry Jacobelli

Jack Li

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-08

Filing date

2004-08-31

Publication date

2005-01-03

2004-08-31 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2005-01-03 Publication of MA27183A1 publication Critical patent/MA27183A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Biomedical Technology (AREA)
Vascular Medicine (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MA27842A 2002-03-08 2004-08-31 Composes oxo-azabicycliques MA27183A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2002/003240 WO2003076416A1 (en)	2002-03-08	2002-03-08	Oxo azabicyclic compounds

Publications (1)

Publication Number	Publication Date
MA27183A1 true MA27183A1 (fr)	2005-01-03

Family

ID=27798761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA27842A MA27183A1 (fr)	2002-03-08	2004-08-31	Composes oxo-azabicycliques

Country Status (25)

Country	Link
EP (1)	EP1492775A2 (xx)
JP (1)	JP2005526070A (xx)
KR (1)	KR20040095270A (xx)
CN (1)	CN1738806A (xx)
AP (1)	AP2004003125A0 (xx)
AR (1)	AR039562A1 (xx)
AU (2)	AU2002249275A1 (xx)
BR (1)	BR0308280A (xx)
CA (1)	CA2478706A1 (xx)
CO (1)	CO5601020A2 (xx)
EA (1)	EA200401053A1 (xx)
EC (1)	ECSP045278A (xx)
IL (1)	IL163818A0 (xx)
IS (1)	IS7414A (xx)
MA (1)	MA27183A1 (xx)
MX (1)	MXPA04008681A (xx)
NO (1)	NO20044041L (xx)
OA (1)	OA12782A (xx)
PA (1)	PA8568501A1 (xx)
PE (1)	PE20031018A1 (xx)
PL (1)	PL372622A1 (xx)
SV (1)	SV2003001495A (xx)
TN (1)	TNSN04169A1 (xx)
UY (1)	UY27700A1 (xx)
WO (2)	WO2003076416A1 (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PA8539501A1 (es)	2001-02-14	2002-09-30	Warner Lambert Co	Compuestos triazolo como inhibidores de mmp
US6962922B2 (en)	2001-10-12	2005-11-08	Warner-Lambert Company Llc	Alkynylated quinazoline compounds
US6894057B2 (en)	2002-03-08	2005-05-17	Warner-Lambert Company	Oxo-azabicyclic compounds
CA2497658A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Chromone derivatives as matrix metalloproteinase inhibitors
AU2003249540A1 (en)	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Fused bicyclic metalloproteinase inhibitors
DE60313350T2 (de)	2002-08-13	2008-01-03	Warner-Lambert Company Llc	Pyrimidin-2,4-dion-derivate als matrix-metalloproteinase-hemmer
CA2494014A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Monocyclic derivatives as matrix metalloproteinase inhibitors
AU2003250466A1 (en)	2002-08-13	2004-02-25	Warner-Lambert Company Llc	3-isoquinolinone derivatives as matrix metalloproteinase inhiitors
PA8578101A1 (es)	2002-08-13	2004-05-07	Warner Lambert Co	Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz
WO2004014923A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Pyrimidinone fused bicyclic metalloproteinase inhibitors
AU2003253186A1 (en)	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors
MXPA05001786A (es)	2002-08-13	2005-04-25	Warner Lambert Co	Derivados de azaisoquinolina como inhibidores de la metaloproteinasa de matriz.
AU2003249539A1 (en) *	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors
WO2005016926A1 (en) *	2003-08-19	2005-02-24	Warner-Lambert Company Llc	Pyrido [3,4-d] pyrimidine derivatives as matrix metalloproteinase-13 inhibitors
DE10360835A1 (de) *	2003-12-23	2005-07-21	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Bicyclische Imidazolverbindungen, deren Herstellung und deren Verwendung als Arzneimittel
MXPA06012333A (es) *	2004-04-30	2007-01-17	Takeda Pharmaceutical	Compuesto de amida heterociclico y uso del mismo como un inhibidor mmp-13.
MXPA06014696A (es) *	2004-06-15	2007-02-12	Astrazeneca Ab	Quinazolonas sustituidas como agentes anticancerosos.
WO2008043087A2 (en)	2006-10-05	2008-04-10	Cv Therapeutics, Inc.	Bicyclic nitrogen-containing heterocyclic compounds for use as stearoyl coa desaturase inhibitors
AR083475A1 (es)	2010-10-18	2013-02-27	Merz Pharma Gmbh & Co Kgaa	Moduladores de receptores de glutamato metabotropicos
CN103524431B (zh) *	2013-09-24	2016-01-13	西安交通大学	3-苄基-4-喹唑啉酮类化合物及其合成方法和应用
JO3512B1 (ar)	2014-03-26	2020-07-05	Astex Therapeutics Ltd	مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
ES2811845T3 (es)	2015-09-23	2021-03-15	Janssen Pharmaceutica Nv	Heterociclos tricíclicos para el tratamiento del cáncer
US11542247B2 (en)	2015-09-23	2023-01-03	Janssen Pharmaceutica Nv	Bi-heteroaryl substitute 1,4-benzodiazepines and uses thereof for the treatment of cancer
FR3046793B1 (fr) *	2016-01-14	2018-01-05	Les Laboratoires Servier	Nouveaux derives de phosphinanes et azaphosphinanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0946095A1 (en) *	1996-12-17	1999-10-06	E.I. Du Pont De Nemours And Company	Fungicidal quinazolinones
PA8539401A1 (es) *	2001-02-14	2002-10-28	Warner Lambert Co	Quinazolinas como inhibidores de mmp-13
PA8539301A1 (es) *	2001-02-14	2002-09-30	Warner Lambert Co	Inhibidores de la metaloproteinasa de la matriz

2002
- 2002-03-08 AU AU2002249275A patent/AU2002249275A1/en not_active Abandoned
- 2002-03-08 WO PCT/EP2002/003240 patent/WO2003076416A1/en not_active Ceased
2003
- 2003-03-04 SV SV2003001495A patent/SV2003001495A/es not_active Application Discontinuation
- 2003-03-06 UY UY27700A patent/UY27700A1/es not_active Application Discontinuation
- 2003-03-06 IL IL16381803A patent/IL163818A0/xx unknown
- 2003-03-06 JP JP2003574636A patent/JP2005526070A/ja not_active Withdrawn
- 2003-03-06 BR BR0308280-6A patent/BR0308280A/pt not_active IP Right Cessation
- 2003-03-06 EA EA200401053A patent/EA200401053A1/ru unknown
- 2003-03-06 EP EP03708181A patent/EP1492775A2/en not_active Withdrawn
- 2003-03-06 PA PA20038568501A patent/PA8568501A1/es unknown
- 2003-03-06 MX MXPA04008681A patent/MXPA04008681A/es unknown
- 2003-03-06 OA OA1200400234A patent/OA12782A/en unknown
- 2003-03-06 CN CNA038048752A patent/CN1738806A/zh active Pending
- 2003-03-06 PE PE2003000218A patent/PE20031018A1/es not_active Application Discontinuation
- 2003-03-06 AP APAP/P/2004/003125A patent/AP2004003125A0/en unknown
- 2003-03-06 WO PCT/EP2003/002277 patent/WO2003076417A2/en not_active Ceased
- 2003-03-06 AU AU2003212307A patent/AU2003212307A1/en not_active Abandoned
- 2003-03-06 PL PL03372622A patent/PL372622A1/xx not_active Application Discontinuation
- 2003-03-06 CA CA002478706A patent/CA2478706A1/en not_active Abandoned
- 2003-03-06 AR ARP030100749A patent/AR039562A1/es not_active Application Discontinuation
- 2003-03-06 KR KR10-2004-7013994A patent/KR20040095270A/ko not_active Ceased
2004
- 2004-08-19 IS IS7414A patent/IS7414A/is unknown
- 2004-08-25 CO CO04082792A patent/CO5601020A2/es not_active Application Discontinuation
- 2004-08-31 MA MA27842A patent/MA27183A1/fr unknown
- 2004-09-03 EC EC2004005278A patent/ECSP045278A/es unknown
- 2004-09-03 TN TNP2004000169A patent/TNSN04169A1/fr unknown
- 2004-09-24 NO NO20044041A patent/NO20044041L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CO5601020A2 (es)	2006-01-31
KR20040095270A (ko)	2004-11-12
MXPA04008681A (es)	2004-12-06
AR039562A1 (es)	2005-02-23
NO20044041L (no)	2004-10-07
TNSN04169A1 (fr)	2007-03-12
CA2478706A1 (en)	2003-09-18
PA8568501A1 (es)	2003-12-19
PL372622A1 (en)	2005-07-25
AU2002249275A1 (en)	2003-09-22
JP2005526070A (ja)	2005-09-02
AU2003212307A1 (en)	2003-09-22
SV2003001495A (es)	2003-11-04
EA200401053A1 (ru)	2005-04-28
AP2004003125A0 (en)	2004-09-30
CN1738806A (zh)	2006-02-22
PE20031018A1 (es)	2004-01-09
IL163818A0 (en)	2005-12-18
WO2003076417A2 (en)	2003-09-18
EP1492775A2 (en)	2005-01-05
UY27700A1 (es)	2003-10-31
WO2003076417A3 (en)	2003-11-13
OA12782A (en)	2006-07-10
WO2003076416A1 (en)	2003-09-18
ECSP045278A (es)	2004-10-26
IS7414A (is)	2004-08-19
BR0308280A (pt)	2004-12-28

Publication	Publication Date	Title
MA27183A1 (fr)	2005-01-03	Composes oxo-azabicycliques
CA2481461A1 (en)	2003-10-30	Derivatives of n-[phenyl(piperidin-2-yl) methyl] benzamide, the preparation method thereof and application of same in therapeutics
MA26989A1 (fr)	2004-12-20	Derives de pyridine inhibiteurs de metalloproteinases de matrice
MA27439A1 (fr)	2005-07-01	Quinazolinones spirocondensees nouvelles et leur utilisation comme inhibiteurs de phosphodiesterase
MA27774A1 (fr)	2006-02-01	Inhibiteurs de phosphatidylinositol 3-kinase
CA2656716C (fr)	2014-10-14	Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
LU90011I2 (fr)	1997-03-11	Remifentanil facultativement sous la forme d'un sel d'addition d'acide pharmaceutiquement acceptable y compris le chlorhydrate de remifentanil
MA56883B1 (fr)	2025-04-30	Dérivés de 2-hydroxycycloalcane-1-carbamoyle
MA30014B1 (fr)	2008-12-01	Derives spirocycliques
MA30784B1 (fr)	2009-10-01	Derives phenyliques et utilisation de ceux-ci en tant qu'immunomodulateurs.
MA27138A1 (fr)	2005-01-03	Composes heteroaryliques condenses a substituant azabicyclique pour le traitement d'une maladie
TNSN07145A1 (fr)	2008-11-21	Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique
TNSN08270A1 (fr)	2009-10-30	Dérivés pyrimidiques destinés à traiter une croissance cellulaire anormale
MA27573A1 (fr)	2005-10-03	Sinomenine et derives de sinomenine, synthese et utilisation.
KR970701698A (ko)	1997-04-12	프로스타글란딘 i₂작용물질로서의 나프탈렌 유도체(naphthalene derivatives as prostaglandin i₂agonists)
CA2496040A1 (en)	2004-03-11	Derivatives of dioxan-2-alkyl carbamates, preparation method thereof and application of same in therapeutics
MA27135A1 (fr)	2005-01-03	Agents antidiabetiques oraux
MA27197A1 (fr)	2005-01-03	Sels de tolterodine
MA31674B1 (fr)	2010-09-01	Dérivés de 7 -alkynyl-1,8-naphthyridones, leur préparation et leur application en thérapeutique
MA57000B1 (fr)	2024-03-29	Dérivés d'alpha-d-galactopyranoside
FR2870541A1 (fr)	2005-11-25	Derives de pyrimidines antigonistes du recepteur de la vitronectine
MA26953A1 (fr)	2004-12-20	Derives de pipérazine pontés.
MA27887A1 (fr)	2006-05-02	Dicetopiperazines substituees et leur utilisation comme antagonistes de l'ocytocine
CA2275192A1 (fr)	1999-12-18	Nouveau procede de preparation de derives de la 4-phenyl-1,2,3,6-tetrahydropyridine et les produits intermediaires mis en oeuvre
MA27712A1 (fr)	2006-01-02	Triazoles utiles en therapeutique