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MA24777A1 - Compose et son utilisation - Google Patents

Compose et son utilisation

Info

Publication number
MA24777A1
MA24777A1 MA25489A MA25489A MA24777A1 MA 24777 A1 MA24777 A1 MA 24777A1 MA 25489 A MA25489 A MA 25489A MA 25489 A MA25489 A MA 25489A MA 24777 A1 MA24777 A1 MA 24777A1
Authority
MA
Morocco
Prior art keywords
compound
Prior art date
Application number
MA25489A
Other languages
English (en)
Inventor
Arthur Griffith-Skinner Nigel
Anthony Hill Derek
William Packham Terence
Mary Edmeades Lorraine
Thronton Hill Graham
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10833464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA24777(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MA24777A1 publication Critical patent/MA24777A1/fr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90Plate chromatography, e.g. thin layer or paper chromatography
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555Hetero-N
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555Hetero-N
    • Y10T436/147777Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA25489A 1998-06-10 1999-03-10 Compose et son utilisation MA24777A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9812413.4A GB9812413D0 (en) 1998-06-10 1998-06-10 Compound and its use

Publications (1)

Publication Number Publication Date
MA24777A1 true MA24777A1 (fr) 1999-10-01

Family

ID=10833464

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25489A MA24777A1 (fr) 1998-06-10 1999-03-10 Compose et son utilisation

Country Status (31)

Country Link
US (1) US6333198B1 (fr)
EP (2) EP1170588A1 (fr)
JP (1) JP2989189B1 (fr)
KR (1) KR100322354B1 (fr)
CN (2) CN1238454A (fr)
AP (3) AP0102286A0 (fr)
AR (1) AR014074A1 (fr)
AT (1) ATE218552T1 (fr)
AU (1) AU2031999A (fr)
BR (1) BR9900984A (fr)
CA (1) CA2265194C (fr)
DE (1) DE69901656T2 (fr)
DK (1) DK0963980T3 (fr)
EA (1) EA000666B1 (fr)
ES (1) ES2178342T3 (fr)
GB (1) GB9812413D0 (fr)
HR (1) HRP990074A2 (fr)
HU (1) HUP9900592A3 (fr)
ID (1) ID22957A (fr)
MA (1) MA24777A1 (fr)
NO (2) NO991151L (fr)
NZ (1) NZ334590A (fr)
PE (1) PE20000332A1 (fr)
PL (1) PL331870A1 (fr)
PT (1) PT963980E (fr)
SG (1) SG85628A1 (fr)
SI (1) SI0963980T1 (fr)
TR (1) TR199900520A3 (fr)
UY (1) UY25946A1 (fr)
YU (1) YU12399A (fr)
ZA (1) ZA991951B (fr)

Families Citing this family (92)

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EP1309557B9 (fr) 2000-12-29 2006-11-15 Pfizer Limited Amlodipine hemimaleate
SI1309555T1 (sl) 2000-12-29 2005-12-31 Pfizer Ltd Postopek izdelave amlodipin-maleata
MXPA03005882A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado amida de amlodipina.
EP1309556B1 (fr) 2000-12-29 2004-11-24 Pfizer Limited Fumarate d'amlodipine
US6653481B2 (en) 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
MXPA03005886A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado de aspartato de amlodipina como antagonista del canal de calcio.
EP1346214A2 (fr) 2000-12-29 2003-09-24 Pfizer Limited Standards de reference destines a la determination de la purete ou de la stabilite de maleate d'amlodipine et procedes correspondants
EP1309554A1 (fr) 2000-12-29 2003-05-14 Synthon Licensing, Ltd. Derive d'amide d'amlodipine
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
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CA2366521C (fr) 2001-12-24 2007-03-06 Brantford Chemicals Inc. Un procede nouveau et efficace de preparation de lamotrigine et d'autres 3,5-diamino-1,2,4-triazines substituees en position 6
AU2003235435A1 (en) * 2002-03-20 2003-10-08 Teva Pharmaceutical Industries Ltd. Crystalline forms of quetiapine hemifumarate
HU225667B1 (en) * 2002-09-20 2007-05-29 Richter Gedeon Nyrt Method for producing high-purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
ES2209639B1 (es) 2002-10-31 2005-08-01 Vita Cientifica, S.L. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y obtencion de su intermedio.
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CA2657076A1 (fr) 2003-08-28 2005-03-17 Teva Pharmaceutical Industries Ltd. Procede de preparation de sels calciques de rosuvastatine
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ES2364143T3 (es) * 2003-12-02 2011-08-25 Teva Pharmaceutical Industries Ltd. Estandar de referencia para caracterización de rosuvastatina.
US7851624B2 (en) * 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
MXPA06008584A (es) * 2004-01-30 2007-04-16 Teva Pharma Polimorfos de acido libre de montelukast.
EP1709002A2 (fr) * 2004-01-30 2006-10-11 Teva Pharmaceutical Industries Ltd. Montelukast de sodium polymorphe
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ES2327762T3 (es) * 2004-04-21 2009-11-03 Teva Pharmaceutical Industries Ltd Procedimiento para preparar montelukast sodico.
TW200613294A (en) * 2004-04-26 2006-05-01 Teva Gyogyszergyar Reszvenytarsasag Process for preparation of mycophenolic acid and ester derivatives thereof
MXPA06005658A (es) * 2004-04-27 2007-04-10 Teva Gyogyszergyar Zartkoruen Proceso para preparacion de micofenolato mofetil, y otros esteres de acido micofenolico.
US7439399B2 (en) * 2004-06-28 2008-10-21 Teva Pharmaceutical Fine Chemicals Processes for the preparation of atomoxetine hydrochloride
CA2561386A1 (fr) * 2004-06-28 2006-01-12 Teva Pharmaceutical Fine Chemicals S.R.L. Mandelate d'atomoxetine et de tomoxetine enantiomeriquement purs
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EP1699773A2 (fr) * 2004-07-20 2006-09-13 Ceva Gyogyszergyar R Szv Nytarsasag Procede pour la preparation de mycophenolate sodique cristalline
CA2568629A1 (fr) * 2004-07-22 2006-02-23 Teva Pharmaceutical Fine Chemicals S.R.L. Polymorphes du chlorhydrate d'atomoxetine
WO2006029253A2 (fr) * 2004-09-04 2006-03-16 Teva Pharmaceutical Industries Ltd. Impurete de valacyclovir isolee, son procede de preparation et son utilisation comme standard de reference
US20060081361A1 (en) * 2004-09-13 2006-04-20 Gabbey Lawrence W Oil cooler with integral filter
ES2263407T1 (es) * 2004-09-28 2006-12-16 Teva Pharmaceutical Industries Ltd Procedimiento para la preparacion de formas de atorvastatina calcica sustancialmente libres de impurezas.
JP2007514777A (ja) * 2004-10-19 2007-06-07 テバ ファーマシューティカル インダストリーズ リミティド テガセロッドマレエートの精製
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US20060194869A1 (en) * 2004-12-23 2006-08-31 Santiago Ini Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof
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US20070167625A1 (en) * 2005-02-22 2007-07-19 Anna Balanov Preparation of rosuvastatin
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EP1866295A2 (fr) * 2005-02-24 2007-12-19 Teva Pharmaceutical Industries Ltd Procedes de preparation d'intermediaire linezolid
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EP1904448B1 (fr) * 2005-07-05 2011-02-02 Teva Pharmaceutical Industries, Ltd. Purification du montélukast
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US20070197529A1 (en) * 2005-12-01 2007-08-23 Viviana Braude Isolated desfluoro-linezolid, preparation thereof and its use as a reference marker and standard
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WO2007069264A2 (fr) * 2005-12-15 2007-06-21 Alembic Limited Nouveaux composes
CA2630478A1 (fr) * 2005-12-27 2007-07-05 Teva Pharmaceutical Industries, Ltd Procedes de preparation de bromhydrate de darifenacine
BRPI0702852A2 (pt) * 2006-03-27 2012-08-07 Teva Pharmaceutical Ind Ltda processos para preparaÇço de Ácido hidroclorÍdrico de memantine substancialmente livre de impurezas, para determinar o grau de pureza do mesmo e para fabricaÇço de produto famacÊutico derivado; seus compostos e componentes
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GB0609835D0 (en) * 2006-05-18 2006-06-28 Pliva Istrazivanje I Razvoj D Impurities of a pharmaceutical product
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CA2649117A1 (fr) * 2006-05-31 2007-12-13 Teva Pharmaceutical Industries Ltd. Utilisation de la resolution enzymatique pour la preparation d'intermediaires de pregabaline
US20080015385A1 (en) * 2006-05-31 2008-01-17 Lilach Hedvati Preparation of (S)-pregabalin-nitrile
EP2032712B1 (fr) * 2006-06-29 2010-02-10 Ivax Pharmaceuticals S.R.O. Régulation de la production de métabolites acides
US20120142919A1 (en) * 2006-08-02 2012-06-07 Medichem, S.A. Method for synthesizing lamotrigine
WO2008019798A1 (fr) * 2006-08-14 2008-02-21 Lonza Ag Procédé de préparation de lamotrigine
US20080242877A1 (en) * 2007-02-26 2008-10-02 Vinod Kumar Kansal Intermediates and processes for the synthesis of Ramelteon
BRPI0803092A2 (pt) * 2007-03-22 2011-08-30 Teva Pharma sìntese de (s)-(+)-3-(aminometil)-5-metil ácido hexanóico, (s)-pregabalina
US20080254520A1 (en) * 2007-04-11 2008-10-16 Eva Gulyas Method for reducing impurity level in mycophenolic acid fermentation
EP2098519A1 (fr) * 2007-05-31 2009-09-09 Teva Pharmaceutical Industries Ltd. Procédé de synthèse du rameltéon et ses intermédiaires
KR20090101462A (ko) * 2007-10-03 2009-09-28 테바 파마슈티컬 인더스트리즈 리미티드 프레가발린-4-엘리미네이트, 프레가발린 5-엘리미네이트, 기준 마커 및 표준물로서의 이들의 용도, 및 이들을 낮은 수준으로 함유하는 프레가발린의 제조 방법
KR20100058660A (ko) * 2007-10-23 2010-06-03 테바 파마슈티컬 인더스트리즈 리미티드 다사티닙 다형체 및 이의 제조 방법
WO2009056993A2 (fr) * 2007-11-01 2009-05-07 Teva Pharmaceutical Industries Ltd. Procédé de synthèse de rameltéon et intermédiaires de ce dernier
US8486927B2 (en) * 2007-11-09 2013-07-16 Thar Pharmaceuticals Crystalline forms of lamotrigine
WO2009151494A1 (fr) * 2008-03-06 2009-12-17 Teva Pharmaceutical Industries Ltd. Procédés de préparation de la o-desméthylvenlafaxine, exempte de ses impuretés dimères
WO2009158343A1 (fr) * 2008-06-23 2009-12-30 Teva Pharmaceutical Industries, Ltd. Synthèse enzymatique stéréosélective de l’ester (s) ou (r)-isobutylglutarique
US20100152468A1 (en) * 2008-10-16 2010-06-17 Teva Pharmaceutical Industries Ltd. Process for the synthesis of ramelteon and its intermediates
CA2795023A1 (fr) * 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Formes cristallines du fumarate de o-desmethylvenlafaxine
WO2012034065A1 (fr) 2010-09-09 2012-03-15 Teva Pharmaceutical Industries Ltd. Intermédiaires d'aliskirène et procédé destiné à analyser la pureté de l'aliskirène
CN102766104A (zh) * 2012-08-20 2012-11-07 三金集团湖南三金制药有限责任公司 一种治疗双向情感障碍及癫痫病药物拉莫三嗪的合成方法
US10189859B2 (en) 2013-12-21 2019-01-29 Nektar Therapeutics Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine
CN110467560B (zh) 2018-05-09 2025-11-25 深圳微芯生物科技股份有限公司 一种苯基氨基丙酸钠衍生物、其制备方法和应用
KR102270026B1 (ko) * 2020-01-31 2021-06-28 현대약품 주식회사 (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법
CN113156009B (zh) * 2021-04-20 2023-12-22 三金集团湖南三金制药有限责任公司 高效液相色谱分析拉莫三嗪的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68380B (fr) 1979-06-01 1981-12-28 Wellcome Found
EP0021120B1 (fr) 1979-06-01 1983-04-06 The Wellcome Foundation Limited Dérivés de la diamino-3,5 triazine-1,2,4, procédé pour la préparation de tels composés et compositions pharmaceutiques les contenant
GB8613183D0 (en) 1986-05-30 1986-07-02 Wellcome Found Triazine salt
GB9426448D0 (en) * 1994-12-30 1995-03-01 Wellcome Found Process
WO1996020934A1 (fr) * 1994-12-30 1996-07-11 The Wellcome Foundation Limited Procede de preparation de lamotrigine
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation

Also Published As

Publication number Publication date
DE69901656D1 (de) 2002-07-11
US6333198B1 (en) 2001-12-25
HRP990074A2 (en) 2000-10-31
EA000666B1 (ru) 2000-02-28
ID22957A (id) 1999-12-23
NO991151D0 (no) 1999-03-10
CN1306210A (zh) 2001-08-01
PL331870A1 (en) 1999-12-20
KR100322354B1 (ko) 2002-02-07
TR199900520A2 (en) 2000-01-21
EP0963980B1 (fr) 2002-06-05
PT963980E (pt) 2002-10-31
ATE218552T1 (de) 2002-06-15
ES2178342T3 (es) 2002-12-16
EP1170588A1 (fr) 2002-01-09
SI0963980T1 (en) 2002-12-31
HUP9900592A2 (hu) 2000-04-28
PE20000332A1 (es) 2000-04-10
CN1238454A (zh) 1999-12-15
HUP9900592A3 (en) 2002-04-29
TR199900520A3 (tr) 2000-01-21
AU2031999A (en) 2000-01-06
EA199900159A1 (ru) 1999-12-29
KR20000005611A (ko) 2000-01-25
DE69901656T2 (de) 2003-01-30
JP2989189B1 (ja) 1999-12-13
BR9900984A (pt) 2000-05-02
EP0963980A3 (fr) 2000-05-31
EP0963980A2 (fr) 1999-12-15
GB9812413D0 (en) 1998-08-05
ZA991951B (en) 1999-08-16
UY25946A1 (es) 2000-12-29
JP2000009714A (ja) 2000-01-14
AP0102286A0 (en) 2000-09-10
CA2265194C (fr) 2000-10-10
YU12399A (sh) 2002-08-12
NO20032753D0 (no) 2003-06-17
AP2001002286A0 (en) 2001-12-31
HU9900592D0 (en) 1999-04-28
NZ334590A (en) 2000-07-28
NO20032753L (no) 1999-12-13
NO991151L (no) 1999-12-13
AP9901481A0 (en) 1999-03-31
DK0963980T3 (da) 2002-09-16
AR014074A1 (es) 2001-01-31
SG85628A1 (en) 2002-01-15

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